Clinical trials: Total Hip Replacement
Total Hip Arthroplasty (THA)
Comparison of Blood Loss Between Cemented and Uncemented Femoral Stems in Anterior Total Hip Arthroplasty
Total hip arthroplasty (THA) yields excellent results. To perform the procedure, the surgeon must make certain decisions, including the choice of fixation method for the femoral implant.
- Trial name
- FEMFIX (NCT07492212)
- Testing
- Total hip replacement with cemented fixation, Total hip replacement with non-cemented fixation
- Where
- 2 sites in France
- Volunteers
- 86 people
- Sponsor
- Clinique du Pré
Revision Total Hip Arthroplasty
Exercise Intervention Targeting Hip Strengthening Compared to Usual Care in Patients Undergoing Revision Hip Replacement
There is sparse evidence on revision total hip replacement (THR), regarding the effectiveness on pain and function, and no consensus exists on optimal rehabilitation after revision THR.
- Trial name
- StrongHip (NCT05657054)
- Testing
- Exercise Intervention Targeting Hip Strengthening, Usual Care
- Where
- 9 sites in Denmark
- Volunteers
- 84 people
- Sponsor
- University of Aarhus
Fracture Neck of Femur
Functional Outcome After Arthroplasty
Bipolar hemiarthroplasty (BA) has long been the preferred treatment and is performed in most fracture neck of femur (FNF) cases. It is justified by the reasonable operative time, low blood loss and acceptable functional outcomes.
- Trial name
- NCT04680572
- Testing
- arthroplasty
- Where
- Egypt
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Osteoarthritis, Blood Loss, Surgical
Non-inferiority Trial of Oral Tranexamic Acid vs. Intravenous Tranexamic Acid in Joint Replacement Surgery
The purpose of this research is to determine if the oral form of a medication (tranexamic acid) to reduce bleeding can be used in place of an intravenous (IV) form, to learn the best way to give tranexamic acid: either a pill by…
- Conditions
- Osteoarthritis, Blood Loss, Surgical, Blood Loss, Postoperative
- Trial name
- NCT02438566
- Testing
- Tranexamic Acid (Oral), Tranexamic Acid (Intravenous)
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- The New England Baptist Hospital
Coxarthrosis, Avascular Necrosis of Hip
Effect of Peri-operative Glucocorticoids on Short-term Functional Outcome After THA
This randomized, single surgeon, placebo controlled, double blind study will be conducted in order to investigate whether or not peri-operative high doses of intravenous glucocorticoids improve short-term functional outcome after…
- Trial name
- DEXA (NCT04317872)
- Testing
- High dose of peri-operative intravenous dexamethasone, Low dose of peri-operative intravenous dexamethasone
- Where
- Belgium
- Volunteers
- 71 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Regional Anesthesia Block, Regional Anesthesia
PENG and LFCN Block Versus FIC Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis Focused on Movement (Retro-PvF)
Total hip arthroplasty is a major surgical procedure performed on a growing number of patients. Optimal pain control with limited muscle weakness is paramount for a swift initiation of physical therapy and ambulation, thus…
- Conditions
- Regional Anesthesia Block, Regional Anesthesia, Total Hip Replacement Surgery, Total Hip Arthroplasty \(THA\)
- Trial name
- Retro-PvF (NCT06342102)
- Testing
- PENG + LFCN block, FIC block
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Ospedale Edoardo Bassini
Stress
The SENSE Study: Surgical ENvironment Stress Evaluation
Surgical procedures such as total hip and knee arthroplasty require a complex set of physical and cognitive skills, expert execution, and inevitably place a high stress load on the surgeon.
- Trial name
- SENSE (NCT07506330)
- Testing
- total joint arthroplasty
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- University College, London
Allergic Contact Dermatitis (ACD)
Use of Silk Fibroin Dressings in Primary Total Hip Arthroplasty
The purpose of this study is to document the incidence of allergic contact dermatitis (ACD) to silk fibroin and 2-octyl cyanoacrylate mesh dressings, to document the incidence of acute wound dehiscence requiring reoperation after…
- Trial name
- NCT07868900
- Testing
- Dermabond PRINEO, Silk fibroin
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- The University of Texas Health Science Center, Houston
Osteoarthritis, Hip, Blood Loss
Bipolar Sealer for Reduction of Blood Loss in Anterior Total Hip Arthroplasties
The overall objectives and purpose of this study is to show that the Smith and Nephew Werewolf Fastseal 6.0 Bipolar Sealer is an effective tool to aide the surgical team in providing significant hemostasis during anterior total…
- Trial name
- NCT05356637
- Testing
- Werewolf Fastseal 6.0
- Where
- 2 sites in United States
- Volunteers
- 75 people
- Sponsor
- North Texas Medical Research Institute, PLLC
Hip Arthropathy
Quality of Life, Functional Outcomes and Costs in Hip Arthroplasty
This prospective observational study aims to collect and analyse data on functional outcomes, quality of life indicators, and costs in patients undergoing primary total hip arthroplasty (hip replacement) surgery.
- Trial name
- NCT05882656
- Testing
- Questionnaire administration
- Where
- Russia
- Volunteers
- 85 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Nerve Block, Quality of Recovery
Study of H-FICB ＆ PENG Block in Elderly Patients' THA on the Post-operative Quality of Recovery
Total joint replacement is projected to become the most common elective surgical procedure in the coming decade; the prevalence of total hip arthroplasty (THA) was estimated as more than 2.5 million individuals in the entire…
- Trial name
- NCT05528822
- Testing
- ultrasound-guided high fascia iliaca compartment block, ultrasound-guided pericapsular nerve group (PENG) block
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Affiliated Hospital of Nantong University
Bone Mineral Density
Changes of Bone Mineral Density in Total Hip Arthroplasty
The study was performed as a prospective, single center study at the Department of Orthopedics, Sacred Heart of Jesus Hospital Vienna, Austria. 117 patients were enrolled in a from January 2016 to May 2017.
- Trial name
- NCT04962854
- Volunteers
- 117 people
- Sponsor
- St. Vincent Hospital, Vienna
Total Hip Replacement
Short Term and Long Term Outcome for Elderly Patients Treated With Total Hip Replacement
The is a retrospective analysis to study the characteristics of elderly patients treated with total hip replacements during past 5 years．
- Trial name
- THR (NCT03120312)
- Testing
- total hip replacement
- Where
- China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Second Hospital of Shanxi Medical University
Total Hip Surgery, Pericapsular Nerve
Comparison of Pericapsular Nerve Group Block and Quadratus Lumborum Block
Adequate pain management following total hip arthroplasty (THA) is a key component for patient satisfaction and early ambulation.
- Conditions
- Total Hip Surgery, Pericapsular Nerve, Quadratus Lumborum
- Trial name
- NCT05654519
- Testing
- PENG/LFCN and QL Blocks
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Hip Replacement, Knee Replacement
Effects of Balance Exercises Circuit in Patients With Hip or Knee Arthroplasty
This study evaluates the effect of balance circuit in patients with more than one year of postoperative total hip or knee arthroplasty.
- Conditions
- Hip Replacement, Knee Replacement, Postural Balance
- Trial name
- BECA (NCT02920151)
- Testing
- balance exercises circuit
- Volunteers
- 65 people
- Sponsor
- Grupo de Estudos e Pesquisas Sobre Atividade Física Para Idosos
Osteoarthritis
Comparison of Anesthetic Techniques on Total Hip Arthroplasty
To compare analgesia and orthopedic rehabilitation milestones in patients receiving either spinal anesthesia (local anesthetic plus opioid) or general endotracheal anesthesia with lumbar plexus block.
- Trial name
- NCT01359865
- Testing
- Lumbar Plexus Block
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Hip Osteoarthritis
Effectiveness of Total Hip Arthroplasty for Patients With Osteoarthritis, a Target Trial Emulation Study
The aim of this study is to assess the effect of total hip arthroplasty on hip disability and pain compared to non-surgery in patients with hip osteoarthritis, using target trial emulation to emulate a randomized controlled trial.
- Trial name
- EAGLE (NCT06263569)
- Testing
- Total hip arthroplasty
- Where
- Netherlands
- Volunteers
- 156 people
- Sponsor
- JointResearch
Rheumatoid Arthritis, Osteoarthritis
A Single Centre Study to Assess the Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-ceramic Bearing in Primary Total Hip Replacement
The purpose of this study is to monitor the performance of the Pinnacle™ Cup with a ceramic-on-ceramic bearing combination in the treatment of patients with hip joint disease requiring a total hip replacement.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00872222
- Testing
- Pinnacle™ Acetabular System
- Where
- Czechia
- Volunteers
- 98 people
- Sponsor
- DePuy International
Arthroplasty, Replacement, Thromboembolism
Pradaxa (Dabigatran Etexilate) 150 mg/q.d. in Patients With Moderate Renal Impairment After Hip or Knee Replacement Surgery
An observational cohort study on safety and efficacy to generate additional data on the benefit/risk profile of the 150 mg dose of Pradaxa in patients with renal impairment
- Trial name
- NCT00847301
- Where
- 53 sites in Austria, France and 5 more
- Volunteers
- 472 people
- Sponsor
- Boehringer Ingelheim
Deep Iliacus Plane Block, Transmuscular Quadratus Lumborum Block
Deep Iliacus Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty
This study aims to compare the analgesic efficacy, opioid consumption, motor function preservation, and quality of recovery of ultrasound-guided deep iliacus plane block (DIPB) and transmuscular quadratus lumborum block (QLB) in…
- Conditions
- Deep Iliacus Plane Block, Transmuscular Quadratus Lumborum Block, Postoperative Analgesia, Total Hip Arthroplasty
- Trial name
- NCT07798830
- Testing
- Deep iliacus plane block, Quadratus lumborum block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Tanta University