Deep Iliacus Plane BlockNCT07798830
Deep Iliacus Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty
A study testing Deep iliacus plane block and Quadratus lumborum block in people with Deep Iliacus Plane Block and Transmuscular Quadratus Lumborum Block, run by Tanta University at 1 site in Egypt.
Trial summary
This study aims to compare the analgesic efficacy, opioid consumption, motor function preservation, and quality of recovery of ultrasound-guided deep iliacus plane block (DIPB) and transmuscular quadratus lumborum block (QLB) in patients undergoing total hip arthroplasty (THA). Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Deep Iliacus Plane Block, Transmuscular Quadratus Lumborum Block, Postoperative Analgesia
- What is being tested?
- Deep iliacus plane block and Quadratus lumborum block
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 80 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Sep 2026to 1 Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age ≥ 18 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status I-III.
- Scheduled for elective unilateral total hip arthroplasty (THA) under spinal anesthesia.
Who cannot join
- Known allergy to local anesthetics or study medications.
- Coagulopathy or anticoagulant therapy contraindicating regional anesthesia.
- Infection at the site of injection.
- Pre-existing neurological deficits affecting the lower limbs.
- Chronic opioid use or opioid dependence.
- Severe hepatic, renal, respiratory, or cardiac disease.
- Body mass index (BMI) > 40 kg/m².
- Contraindications to spinal anesthesia.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt1 site, 1 recruiting
- Recruiting
Tanta University
Tanta, El-Gharbia, 31527
Mohammed S Elsharkawy, MD, 00201148207870, mselsharkawy@med.tanta.edu.eg
About this study
Official title: Deep Iliacus Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty: A Randomized Clinical Trial
This study aims to compare the analgesic efficacy, opioid consumption, motor function preservation, and quality of recovery of ultrasound-guided deep iliacus plane block (DIPB) and transmuscular quadratus lumborum block (QLB) in patients undergoing total hip arthroplasty (THA).
Read the detailed description
Total hip arthroplasty (THA) is one of the most commonly performed orthopedic procedures for the treatment of end-stage hip disorders. It is indicated for conditions such as osteoarthritis, rheumatoid arthritis, avascular necrosis, and femoral neck fractures.
The quadratus lumborum block (QLB) is an ultrasound-guided fascial plane block that has been increasingly used for analgesia in hip surgery.
The deep iliacus plane block (DIPB) is a recently introduced regional anesthesia technique specifically developed for hip analgesia. The block is performed by depositing local anesthetic in the deep fascial plane between the iliacus muscle and the iliac bone.
- Conditions
- Deep Iliacus Plane Block, Transmuscular Quadratus Lumborum Block, Postoperative Analgesia, Total Hip Arthroplasty
- Being tested
- Deep iliacus plane block, Quadratus lumborum block
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Deep iliacus plane blockDrug
Patients will receive ultrasound-guided deep iliacus plane block (DIPB) using 25 mL of 0.25% bupivacaine.
Quadratus lumborum blockDrug
Patients will receive ultrasound-guided transmuscular quadratus lumborum block (QLB) using 25 mL of 0.25% bupivacaine.
| Study group | Role | What they receive |
|---|---|---|
| Group DIPB | Experimental | Patients will receive ultrasound-guided deep iliacus plane block (DIPB) using 25 mL of 0.25% bupivacaine. Receives: Drug: Deep iliacus plane block |
| Group QLB | Experimental | Patients will receive ultrasound-guided transmuscular quadratus lumborum block (QLB) using 25 mL of 0.25% bupivacaine. Receives: Drug: Quadratus lumborum block |
What is being measured
The primary outcome is the main question the study is designed to answer.
Degree of pain
Measured: Each patient will be instructed about postoperative pain assessment with VAS. VAS (0 represents "no pain" while 10 represents "the worst pain imaginable"). VAS will be assessed at post-anesthesia care unit (PACU), 2, 4, 6, 12, and 24 h postoperatively.
Secondary outcomes (5)
Total morphine consumption
Rescue analgesia of morphine will be given as 3 mg bolus if the Visual Analog Scale (VAS) > 3 to be repeated after 30 min if pain persists until the VAS < 4.
Measured: 24 hours postoperatively
Time to the 1st rescue analgesia
Time to the first request for the rescue analgesia will be recorded from the end of block to first dose of morphine administrated.
Measured: 24 hours postoperatively
Time for ambulation
Time to ambulation: the time interval (in hours) from the end of surgery to the first successful mobilization of the patient, defined as the ability to stand and walk at least 3-5 steps with or without assistance
Measured: 24 hours postoperatively
Length of hospital stay
Length of hospital stay will be recorded from admission till the discharge from hospital.
Measured: 24 hours postoperatively
Incidence of adverse events
Incidence of adverse events such as bradycardia, hypotension, nausea, vomiting, respiratory depression, or any other complication will be recorded.
Measured: 24 hours postoperatively
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Sep 2026
- Study start1 Sep 2026
- Primary completion1 Mar 2027 (estimated)
- Study completion1 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Deep Iliacus Plane BlockStudies of the same condition, open and under way.
- More trials run by Tanta UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Tanta University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohammed Said ElSharkawy, Tanta University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07798830
- Sponsor's protocol ID
- 36265PR111/6/26
- Status last verified
- Sep 2026
- First submitted
- 24 Aug 2026
- Last updated
- 2 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
Study at a glance
From the registry record, last updated by the sponsor on 2 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Deep Iliacus Plane Block Versus Transmuscular Quadratus Lumborum Block for Postoperative Analgesia After Total Hip Arthroplasty: A Randomized Clinical Trial
- ClinicalTrials.gov ID
- NCT07798830
- Acronym / sponsor ID
- 36265PR111/6/26
- Conditions
- Deep Iliacus Plane Block, Transmuscular Quadratus Lumborum Block, Postoperative Analgesia, Total Hip Arthroplasty
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Tanta UniversityUniversity, hospital or other
- Study start
- 1 Sep 2026 (actual)
- Primary completion
- 1 Mar 2027 (estimated)
- Study completion
- 1 Mar 2027 (estimated)
- First posted
- 1 Sep 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare the analgesic efficacy, opioid consumption, motor function preservation, and quality of recovery of ultrasound-guided deep iliacus plane block (DIPB) and transmuscular quadratus lumborum block (QLB) in patients undergoing total hip arthroplasty (THA).
Detailed description
Total hip arthroplasty (THA) is one of the most commonly performed orthopedic procedures for the treatment of end-stage hip disorders. It is indicated for conditions such as osteoarthritis, rheumatoid arthritis, avascular necrosis, and femoral neck fractures.
The quadratus lumborum block (QLB) is an ultrasound-guided fascial plane block that has been increasingly used for analgesia in hip surgery.
The deep iliacus plane block (DIPB) is a recently introduced regional anesthesia technique specifically developed for hip analgesia. The block is performed by depositing local anesthetic in the deep fascial plane between the iliacus muscle and the iliac bone.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group DIPB | Experimental | Drug: Deep iliacus plane blockPatients will receive ultrasound-guided deep iliacus plane block (DIPB) using 25 mL of 0.25% bupivacaine. |
| Group QLB | Experimental | Drug: Quadratus lumborum blockPatients will receive ultrasound-guided transmuscular quadratus lumborum block (QLB) using 25 mL of 0.25% bupivacaine. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Age ≥ 18 years.
- Both sexes.
- American Society of Anesthesiologists (ASA) physical status I-III.
- Scheduled for elective unilateral total hip arthroplasty (THA) under spinal anesthesia.
Key exclusion criteria (8 listed)
- Known allergy to local anesthetics or study medications.
- Coagulopathy or anticoagulant therapy contraindicating regional anesthesia.
- Infection at the site of injection.
- Pre-existing neurological deficits affecting the lower limbs.
- Chronic opioid use or opioid dependence.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Deep iliacus plane blockPatients will receive ultrasound-guided deep iliacus plane block (DIPB) using 25 mL of 0.25% bupivacaine. | Drug | Group DIPB |
| Quadratus lumborum blockPatients will receive ultrasound-guided transmuscular quadratus lumborum block (QLB) using 25 mL of 0.25% bupivacaine. | Drug | Group QLB |
Primary outcome
Degree of pain
Time frame: Each patient will be instructed about postoperative pain assessment with VAS. VAS (0 represents "no pain" while 10 represents "the worst pain imaginable"). VAS will be assessed at post-anesthesia care unit (PACU), 2, 4, 6, 12, and 24 h postoperatively.
5 secondary outcomes
Total morphine consumption
Time frame: 24 hours postoperatively
Time to the 1st rescue analgesia
Time frame: 24 hours postoperatively
Time for ambulation
Time frame: 24 hours postoperatively
Length of hospital stay
Time frame: 24 hours postoperatively
Incidence of adverse events
Time frame: 24 hours postoperatively
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Sep 2026.
- Individual participant dataSharing planned: Yes. The data will be available upon a reasonable request from the corresponding author after the end of study for one year.
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PENG vs Deep Iliacus Plane Block in Intertrochanteric Femur Fractures
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DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery
Hip Arthroplasty, Postoperative Pain
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Deep iliacus plane block and Quadratus lumborum block in people with Deep Iliacus Plane Block and Transmuscular Quadratus Lumborum Block, run by Tanta University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 2 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Mohammed S Elsharkawy, MD (00201148207870, mselsharkawy@med.tanta.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Degree of pain (time frame: Each patient will be instructed about postoperative pain assessment with VAS. VAS (0 represents "no pain" while 10 represents "the worst pain imaginable"). VAS will be assessed at post-anesthesia care unit (PACU), 2, 4, 6, 12, and 24 h postoperatively.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Sep 2026.