Clinical trials: Tooth Sensitivity
Hypersensitivity Dentin, Fluoride Varnishes
Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity
This randomized controlled clinical trial aims to determine whether different fluoride varnish formulations reduce dentin hypersensitivity (DH) in young adults diagnosed with DH.
- Trial name
- NCT07286344
- Testing
- Aqueous fluoride varnish, 9,500 ppm NaF, Resin/rosin-based varnish, 22,600 ppm NaF
- Where
- Chile
- Volunteers
- 92 people
- Sponsor
- University of Concepcion, Chile
Dentin Sensitivity
Clinical Benefit of a Mouthrinse for the Treatment of Dentine Hypersensitivity
This study is to evaluate the benefit and tolerability of a Mouthrinse (IQP-OLP-101) in the treatment of dentine hypersensitivity.
- Trial name
- NCT03232255
- Testing
- Mouthrinse (IQP-OLP-101)
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- InQpharm Group
Dentin Hypersensitivity, Post Operative Sensitivity Control
Dipotassium Oxalate for Postoperative Sensitivity in NCCLs
Postoperative sensitivity is a common complication following Class V composite restorations, particularly in non-carious cervical lesions (NCCLs).
- Trial name
- DIPOX-RCT (NCT07540299)
- Testing
- Dipotassium Oxalate Gel
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Postgraduate Medical Institute, Lahore
Dentin Hypersensitivity
The Effect of the Egg Shell Nanoparticles Combined With Titanium Dioxide Nanoparticles
Dentin hypersensitivity is one of the most commonly occurring clinical dental conditions which is characterized by short and sharp pain which arises from exposed dentin in response to external stimuli, which typically are…
- Trial name
- NCT06025084
- Testing
- Egg Shell nanoparticles
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Egymedicalpedia
Dentine Hypersensitivity
Neurological Responses in Patients with Dentine Hypersensitivity
Dentine hypersensitivity (also known as sensitive teeth) is a common dental condition in which the dentine, a layer of sensitive hard tissue under the enamel of the teeth, becomes exposed making the teeth sensitive to stimuli…
- Trial name
- NCT06633627
- Testing
- Recording of brain activity using electroencephalography (EEG)
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Inflammation, Pulpitis
Assessing of Tooth Sensitivity Using Ibuprofen Before in Office-tooth Bleaching
Ibuprofen has been recognized as anti-inflammatory and analgesic. The purpose of this study is to determine the effect of ibuprofen 400 mg on tooth sensitivity (TS) caused by in-office bleaching.
- Trial name
- NCT01530217
- Testing
- Ibuprofen.
- Volunteers
- 30 people
- Sponsor
- Universidade Estadual de Ponta Grossa
Dentin Sensitivity
Effectiveness of a Homecare Dentin Hypersensitivity Gel
Aim: To evaluate the effectiveness of a desensitizing gel for topical and home use in the treatment of dentin hypersensitivity (DH) through a randomized clinical trial, double-blind, with three parallel treatment.
- Trial name
- ECR (NCT02128633)
- Testing
- 5% sodium fluoride, potassium oxalate 5%, strontium chloride 10%, Fluoride neutral NaF gel 2 %
- Where
- Brazil
- Volunteers
- 126 people
- Sponsor
- Universidade Federal de Santa Maria
Dentin Sensitivity
A Study to Measure the Efficacy of a Toothpaste on Dentinal Hypersensitivity
Double blind parallel study to measure the efficacy of a toothpaste containing calcium-silicate/phosphate on dentinal hypersensitivity compared to a control toothpaste containing fluoride
- Trial name
- NCT03244618
- Testing
- CSSP Toothpaste, Fluoride Toothpaste
- Where
- United Kingdom
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Dentin Hypersensitivity, Dentin Sensitivity
Fluoride Varnish X Glass Ionomer Sealant on Cervical Dentin Hypersensitivity
Dentin hypersensitivity (DH) can be defined as acute, short-duration pain from open dentin tubules in exposed dentin. The symptom of DH is subjective and varies from patient to patient and may present as mild discomfort or as a…
- Trial name
- NCT04591444
- Testing
- Fluoride Varnish, Glass Ionomer Sealant
- Where
- Brazil
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dentin Sensitivity
A Pilot Clinical Study to Evaluate the Safety and Efficacy of Marketed Oxalate Strips Compared to a Marketed Safety Pen
This pilot study will evaluate the safety and effectiveness of a marketed sensitivity strip on existing dentinal hypersensitivity compared to a marketed sensitivity pen.
- Trial name
- NCT02384044
- Testing
- Crest® Sensi-Stop™ Strips, Colgate® Sensitivity Relief Pen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Sensitivity
A Clinical Study to Evaluate the Effectiveness of an Test Toothpaste for the Relief of Dentin Hypersensitivity in a Chinese Population
The purpose of this study is to evaluate the clinical efficacy of a 0.454 percent (%) weight/weight (w/w) stannous fluoride (SnF2) toothpaste in reducing dentin hypersensitivity (DH) to an evaporative (air) stimulus and tactile…
- Trial name
- NCT07352956
- Testing
- Test toothpaste, Sodium fluoride toothpaste
- Where
- China
- Volunteers
- 177 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
Clinical Trial to Compare the Efficacy of a Fluoride Gel and a Dental Bonding Agent in Treatment of Tooth Sensitivity
This study compares the efficacy of two dental interventions in the treatment of cervical dentine sensitivity. The participants will be selected from adult dental patients registered at a general dental practice in West Sussex…
- Trial name
- NCT02919202
- Testing
- Colgate Fluoride Varnish Suspension. 2.26% Sodium Fluoride., Self-etching Dentine Bonding Agent
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- University of Kent
Dentin Sensitivity
A Clinical Study to Evaluate the Anti-Sensitivity Efficacy of a Stannous Fluoride Toothpaste in a Population of Dentin Hypersensitivity Sufferers
The aim of this study is to confirm the clinical Dentin Hypersensitivity (DH) efficacy of a 0.454 percent (%) Stannous Fluoride (SnF2) toothpaste.
- Trial name
- NCT06354270
- Testing
- Stannous fluoride toothpaste, Regular fluoride toothpaste (Crest Cavity Protection)
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- HALEON
Dental Caries, Dental Restoration Failure
Effect on Placement Tecnique of Bulkfill Composite
The objective of this study was to evaluate the clinical performance of a bulk-fill composite resin (3M ESPE Filtek Bulk Fill, St Paul, MN, USA) in restorations placed in occlusal cavities by comparing different placement…
- Trial name
- NCT07673952
- Testing
- bulk tecnique, incrementally technique
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Gingival Recession, Mucogingival Deformity - Insufficient Keratinized Tissue
Modified Coronally Advanced Tunnel for Mandibular Lingual Root Coverage
This study will follow adults who have gum recession on the tongue side of the lower teeth. Participants will receive a gum surgery called the Modified Coronally Advanced Tunnel technique with a connective tissue graft taken from…
- Trial name
- NCT07590960
- Testing
- Modified Coronally Advanced Tunnel with Connective Tissue Graft
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Dentin Sensitivity
A Pilot Study to Assess Nominal Versus Controlled Stimuli on Dentinal Hypersensitivity
This pilot study will evaluate the use of nominal stimuli to assess dentinal hypersensitivity response relative to a clinically-controlled stimulus.
- Trial name
- NCT02406573
- Testing
- Crest® Sensi-Stop™ Strips
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Sensitive Dentin, Hypomineralization Molar Incisor
BIOSILITACE AS A DESENSITIZING AGENTIN HMI
Molar-Incisor Hypomineralization (MIH) is a qualitative enamel defect caused by systemic hypomineralization that affects one to four first permanent molars, and may or may not involve incisors.
- Conditions
- Sensitive Dentin, Hypomineralization Molar Incisor, Pain
- Trial name
- BDAHMI (NCT07080645)
- Testing
- Pain Relieving, topical application
- Where
- 2 sites in Brazil
- Volunteers
- 42 people
- Sponsor
- University of Sao Paulo
Dentin Sensitivity
A Clinical Study to Determine the Safety and Effectiveness of Dentinal Hypersensitivity Treatment With Two Different Toothbrushes
This study will determine the effects toothbrush type (power or manual) has on the safety and effectiveness of professional dentinal hypersensitivity treatment with a marketed oxalate-containing solution.
- Trial name
- NCT02513212
- Testing
- Potassium Oxalate, Stannous fluoride paste, Manual toothbrush
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Procter and Gamble
Dentin Sensitivity
Study to Evaluate the Effectiveness of Test Dentifrice in the Relief of Dentinal Hypersensitivity
The purpose of this study is to compare the clinical efficacy of test fluoride dentifrice in reducing Dentin Hypersensitivity (DH) with that of a standard fluoride dentifrice, as measured by evaporative air sensitivity after 12…
- Trial name
- NCT07317128
- Testing
- Test Dentifrice, Colgate Sensitive ProRelief, Colgate Triple Protection
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- HALEON
Molar Incisor Hypomineralisation
Correlation Between Colour and Hypersensitivity of First Permanent Molars With Molar Incisor Hypomineralisation (MIH)
Cheese molars (MIH: molar incisor hypomineralisation) can be recognized not only by their colour abnormalities but also by their hypersensitivity.
- Trial name
- NCT07727044
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Basel