Clinical trials: Tooth Injuries
Dental Diseases
Intensive Preventative Dental Program Pilot Study
Radiation therapy to treat cancer may cause a dry mouth from damage to salivary glands which may increase the risk of cavities on the teeth.
- Trial name
- IPDP (NCT07218068)
- Testing
- Fluoride varnish, Regular Care, Medical Oncology Care Team
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Wake Forest University Health Sciences
Neurologic Diseases, Hemiparesis
NuroSleeve Powered Brace & Stimulation System to Restore Arm Function
The purpose of this study is to investigate if a person with weakness or paralysis in one or both arms, can use the NuroSleeve combined powered arm brace (orthosis) and muscle stimulation system to help restore movement in one…
- Conditions
- Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies
- Trial name
- NCT04798378
- Testing
- Neurosleeve
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Impacted Third Molar Tooth
Effectiveness of Platelet Rich Plasma in Wound Healing
Purpose: This prospective randomized comparative clinical study was conducted to assess the effect of platelet-rich plasma (PRP) gel on soft tissue healing and bone regeneration potential on lower third molar extraction sockets.
- Trial name
- NCT02831374
- Testing
- Local anesthesia, surgical extraction of impacted third molar, Preparation of PRP gel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Linyi People's Hospital
Wisdom Teeth Extraction or Jaw Implant
Levels of Fear, Anxiety and Wound Healing Among Aental Surgery Patients Under Local Versus General Anesthesia
Tooth extraction is one of the most common procedures in dentistry. Surgical extraction of damaged wisdom teeth involves bone resection and injury to the soft tissue.
- Trial name
- NCT06380608
- Testing
- Local anesthesia, General anesthesia
- Where
- Israel
- Volunteers
- 46 people
- Sponsor
- Zoya Haitov Ben Zikri
Connective Tissue Graft, Gum Recession
Microderm for Root Coverage Procedures
This randomized pilot study will compare Acellular Dermal Matrix (ADM) and a microsurfaced Acellular Dermal Matrix (mADM) for wound healing, root coverage, gum tissue coverage of the surgical site, blood flow to the site, and…
- Trial name
- NCT07203326
- Testing
- Alloderm, MicroDerm
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Non-restorable Teeth, Intraoral Surgical Incisions
Efficacy of Using Knotless Barbed Suture vs N-Butyl Cyanoacrylate Glue Tissue Adhesive for Closure of Intraoral Surgical Incisions
This clinical study aims to compare the efficacy of knotless barbed sutures versus N-butyl cyanoacrylate glue tissue adhesive for the closure of intra-oral surgical incisions, with traditional PGA vicryl sutures as a control…
- Conditions
- Non-restorable Teeth, Intraoral Surgical Incisions, Wound Closure, Surgical Tooth Extraction
- Trial name
- KBA vs CA (NCT07491276)
- Testing
- PDO Knotless Barbed Suture, N-Butyl Cyanoacrylate Glue (PERIACRYL), 3/0 Resorbable PGA Suture
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Future University in Egypt
Head and Neck Cancer, Caries, Dental
Post-radiation Dental Disease Amongst Head and Neck Cancer Patients
Background Post-radiotherapy head and neck cancer (HANC) patients are at increased risk of dental caries and periodontal disease due to radiation-related damage to the teeth and salivary glands.
- Conditions
- Head and Neck Cancer, Caries, Dental, Periodontal Diseases, Radiotherapy Side Effect
- Trial name
- NCT03703648
- Testing
- Radiotherapy (curative) for head and neck cancer
- Where
- United Kingdom
- Volunteers
- 215 people
- Sponsor
- Belfast Health and Social Care Trust
Idiopathic Toe Walking, Cerebral Palsy
The Effect of Targeting the Plantaris Muscle-tendon in Surgical Correction of Ankle Equinus in Children
Tight ankle muscles can produce ankle equinus (limited ability to pull the foot upward) and occur often in children, significantly impacting their ability to walk.
- Conditions
- Idiopathic Toe Walking, Cerebral Palsy, Hereditary Spastic Paraparesis, Traumatic Brain Injury
- Trial name
- Plantaris Sx (NCT07090057)
- Testing
- Tendoachilles (TA) lengthening or gastrocnemius (GN) recession, then Plantaris tenotomy, Plantaris tenotomy, then Tendoachilles (TA) lengthening or gastrocnemius (GN) recession
- Where
- Canada
- Volunteers
- 42 people
- Sponsor
- University of Alberta
Tooth Fractures (Class IV), Composite Resins
Evaluation of Clinical Performance, Shade Matching, and Patient Satisfaction of Different Resin Composite Layering Techniques Using 3D Printed Cast
The aim of this randomized clinical trial is to compare different resin composite layering techniques (monochromatic, complex multichromatic, and single-shaded structurally-colored composite) using 3D printed casts for the…
- Conditions
- Tooth Fractures (Class IV), Composite Resins, Permanent Anterior Teeth
- Trial name
- NCT07813949
- Testing
- Resin Composite Layering Techniques using 3D Printed Casts
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Vitamin D Deficiency, Obesity
D-tecting Disease - From Exposure to Vitamin D During Critical Periods of Life
Vitamin D deficiency is common among otherwise healthy pregnant women and may have consequences for them as well as the early development and long-term health of their children.
- Conditions
- Vitamin D Deficiency, Obesity, Diabetes Mellitus, Pre-Eclampsia
- Trial name
- D-tect (NCT03330301)
- Testing
- D-tect
- Where
- Denmark
- Volunteers
- 222,776 people
- Sponsor
- Bispebjerg Hospital
Tooth, Impacted
Bradykinin Receptors and Pain
This study will examine whether bradykinin receptors are produced at the site of wisdom tooth extraction and if they contribute to the amount of inflammation and pain that follows surgery.
- Trial name
- NCT00083356
- Testing
- Wisdom tooth extraction
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- National Institute of Nursing Research (NINR)
Irreversible Pulpitis
Outcome Following Use of NaOCl and Chlorhexidine as Wound Lavage Agents
The goal of this clinical trial is to to compare effect of wound lavage agents NaOCl and Chlorhexidine on the outcome of partial pulpotomy in mature permanent posterior teeth with signs and symptoms indicative of irreversible…
- Trial name
- NCT06240130
- Testing
- Partial pulpotomy
- Where
- India
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Caries,Dental, Broken Teeth
Evaluation of CAD/CAM Onlays Fabricated by Subtractive Versus Additive Digital Manufacturing Techniques.
Aim of the study: The aim of this RCT is to evaluate CAD/CAM onlays fabricated by subtractive technique (brilliant crios) versus additive technique (varseosmile crown plus material), in terms of clinical functional evaluation…
- Conditions
- Caries,Dental, Broken Teeth, Fracture Tooth, Defective Dentition
- Trial name
- NCT05943782
- Testing
- onlay manufactured by milling, Onlay manufactured by 3D printing
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Tooth Discoloration, Tooth Fractures
One Year Clinical Evaluation of IPS Empress CAD Versus Polished Celtra Duo Ceramic Laminate Veneers
When restoring teeth with IPS Empress laminate veneers, fracture of restorations may occur. So, material with higher mechanical properties is required.
- Conditions
- Tooth Discoloration, Tooth Fractures, Diastema
- Trial name
- NCT03136276
- Testing
- IPS Empress CAD, polished Celtra Duo
- Volunteers
- 36 people
- Sponsor
- Cairo University
Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC)
Assessment of Oral Health-Related Quality of Life in Preschool-Aged Children in Alto Alentejo
The observational study aims to improve understanding of Oral Health-Related Quality of Life (OHRQoL) among preschool children in the District of Portalegre, Portugal, by examining the roles of sociodemographic, behavioral, and…
- Conditions
- Oral Health Related Quality of Life (OHRQoL), Early Childhood Caries (ECC), Traumatic Dental Injuries, Gingivitis
- Trial name
- NCT07648121
- Where
- Portugal
- Volunteers
- 454 people, healthy volunteers welcome
- Sponsor
- University of Lisbon
Teeth Mesial Drift, Bone Injury
Biological Anchorage With Selective Micro-osteoperforations (MOPs) in Canine Distalization
To evaluate the effect of selective micro-osteoperforations (MOPs) on the amount of distal movement of the upper canine, the mesio-distal inclination of the canine and the messiah movement of the upper first molar.
- Conditions
- Teeth Mesial Drift, Bone Injury, Orthodontic Pathological Resorption of External Root
- Trial name
- NCT03741504
- Testing
- micro-osteoperforations (MOPs)
- Where
- 2 sites in Colombia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fundación Universitaria CIEO
Tooth Avulsion
Impact of a Alveolar Ridge Preservation Technique on the Need of Performing Guided Bone Regeneration for Dental Implant Placement
The aim of this study is to investigate how a socket preservation procedure may reduce the need of guided bone regeneration surgery after tooth extraction and facilitate the placement of a dental implant in the optimal…
- Trial name
- NCT04299750
- Testing
- Tooth extraction and Alveolar ridge preservation, Tooth extraction
- Where
- Italy
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Simone Lumetti
Malocclusion, Crowded Teeth
Evaluation of the Levels of Pain and Discomfort Between Two Methods of Correcting Misaligned Teeth
Applying flapless piezocision corticotomies on the alveolar bone and separating anterior mandibular teeth using a piezosurgery device (i.e.
- Conditions
- Malocclusion, Crowded Teeth, Surgical Incision
- Trial name
- NCT02975765
- Testing
- Piezosurgery
- Where
- Syria
- Volunteers
- 36 people
- Sponsor
- Damascus University
Post-extraction Pain (PEP), Post-extraction Lip or Cheek Biting Injury (PEBI)
Evaluation of Post-operative Discomforts in Children After Extraction of Temporary Teeth
This prospective observational study aim to evaluate discomforts after extraction of temporary tooth under local anesthesia. The first objective is to describe the prevalence of the post-extraction pain (PEP), post-extraction…
- Conditions
- Post-extraction Pain (PEP), Post-extraction Lip or Cheek Biting Injury (PEBI), Post-extraction Bleeding (PEB), Tooth Removal
- Trial name
- DEXTRAFANT (NCT03878173)
- Testing
- No intervention
- Where
- France
- Volunteers
- 125 people
- Sponsor
- Nantes University Hospital
Carpal Tunnel Syndrome, Median Nerve Entrapment
Hydrodissection in Carpal Tunnel Syndrome
The aim of this study was to compare the effectiveness of perineural hydrodissection methods performed with 5 mL D5W solution and three different injection techniques [ultrasound-guided in-plane, ultrasound-guided out-of-plane…
- Trial name
- KTS (NCT07207460)
- Testing
- Comparison of three different injection techniques using hydrodissection with 5% dextrose in the treatment of CTS
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Ankara City Hospital Bilkent