Clinical trials: Tooth Extractions
Tooth Extraction, Alveolar Bone Loss
Autogenous Dentin Graft for Alveolar Ridge Preservatio
When a tooth is extracted, the bone around the empty socket naturally shrinks over time, which can make it difficult to place a dental implant later without additional bone-building procedures.
- Trial name
- ARF-PRF (NCT07789262)
- Testing
- Autogenous Dentin Graft, Platelet-Rich Fibrin (PRF), Freeze-Dried Bone Allograft (FDBA)
- Where
- Turkey (Türkiye)
- Volunteers
- 9 people
- Sponsor
- Ankara Yildirim Beyazıt University
Anesthesia, Local
Efficiency of Single Buccal Infiltration Versus Buccal and Intrapapillary Infiltration
Everyday practice in dentistry is based on giving the painless injection and achieving adequate local anesthesia. Various techniques of reducing injection pain in children can be broadly categorized as psychological and physical.
- Trial name
- NCT04458142
- Testing
- Single buccal infiltration
- Volunteers
- 25 people
- Sponsor
- Cairo University
Tooth Extraction
Safety, Tolerability and Efficacy Study of TT-173 in Healthy Volunteers After Tooth Extraction
The purpose of this study is to evaluate the safety, tolerability and efficacy of TT-173 in healthy volunteers after tooth extraction.
- Trial name
- NCT01595360
- Testing
- TT-173
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Thrombotargets Europe S.L
Class II Division 1 Malocclusion
Bilateral Premolar Extraction vs Distalization: A Randomised Clinical Trial
Rationale: Class II Division 1 malocclusion is characterized by upper anterior teeth protrusion resulting in upper lip protrusion and convex facial profile, which are considered esthetically unfavorable.
- Trial name
- NCT04743258
- Testing
- MAXILLARY PREMOLAR EXTRACTION, DISTALIZATION
- Where
- India
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Tooth Extraction Site Healing
Efficacy of Albumin Platelet Rich Fibrin on Complications After Mandibular Third Molar Extraction.
Sixteen patients with bilateral impacted lower third molars seeking treatment will be recruited from the out-patient clinic of Oral and Maxillofacial Surgery Department, Faculty of Dentistry at Mansoura University.
- Trial name
- NCT07153133
- Testing
- Alb-PRF Autologous Albumin Gel, Surgical extraction of impacted third molar
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Mansoura University
Oral Hygiene
Clinical Study to Investigate the Tooth Stain Removal Efficacy of Two Experimental Toothpastes Compared to a Standard Toothpaste When Used Twice Daily for 8 Weeks
The aim of this study is to investigate the stain removal efficacy of 2 experimental anti-dentin hypersensitivity (DH) dentifrices with four and eight weeks twice daily use.
- Trial name
- NCT05459558
- Testing
- Experimental Dentifrice 1, Experimental Dentifrice 2, Reference Dentifrice
- Where
- United States
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- HALEON
Endodontic Disease
Effect of Three Mechanical Systems on Removal of Endotoxins From Necrotic Teeth
The patients will be randomly assigned into two equal groups Group : OneShape Group: ProtaperNext Endodontics procedure steps: Patient will be anesthetized by using infiltration local anesthesia or nerve block according to the…
- Trial name
- RCT2019 (NCT04200638)
- Testing
- ProTaper Next
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Caries Arrested
Selective Versus Stepwise Removal of Deep Carious Lesions in Permanent Teeth Using Different Medicaments
The study involved 54 adult patients between the ages of 18 and 50 years who had a posterior permanent tooth with a deep occlusal (Class I) carious lesion that extended to the inner third of the dentin (D3) and divided them into…
- Trial name
- NCT06585436
- Testing
- partial caries removal
- Where
- Egypt
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Impacted Third Molar Tooth
The Effect of Melatonin Application Following Removal of Impacted Third Molar
In the present study, the main hypothesis hypothesizes that the local application of melatonin in the post-extraction socket produces favorable differences in the immediate postoperative period, as anti-inflammatory, analgesic…
- Trial name
- NCT04424875
- Testing
- 3 mg melatonin
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Fayoum University
Dental Extraction
Human Placenta Extract Use in Socket Preservation
This split-mouth pilot study evaluates the effectiveness of flowable decellularized Human Placental Connective Tissue Matrix (HPCTM) in alveolar ridge preservation following tooth extraction.
- Trial name
- NCT06915675
- Testing
- Placental Extract, Allograft
- Where
- Lebanon
- Volunteers
- 10 people
- Sponsor
- Saint-Joseph University
Missing Tooth, Osseointegration Failure of Dental Implant
X-space Implants in Post-extraction Sites.
Several recent systematic reviews have highlighted how the macrodesign of dental implants can influence stress distribution and biomechanical and biological behavior in implants immediately inserted in post-extraction sites.
- Trial name
- NCT04492111
- Testing
- post-extraction dental implant
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Bari
Gingival and Periodontal Disease, Caries, Dental
Clinical Evaluation of the Antibacterial Activity of Thioglycosides Extracted from White Mustard - Bamberka in Oral Hygiene. Evaluation of Periodontal Parameters and Oral Microbiota in Patients.
Brief Summary The goal of this randomized clinical trial is to evaluate the clinical and antibacterial effects of a herbal toothpaste containing white mustard (Sinapis alba) extract in patients diagnosed with gingivitis.
- Trial name
- NCT06908265
- Testing
- Toothpaste including mustard extract
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Periodontitis Complex
Periodontal Regeneration Versus Tooth Extraction and Replacement Denture in Teeth With Periodontal Hopeless Prognosis
Periodontal regeneration can change tooth prognosis and represents an alternative to extraction in teeth compromised by severe intrabony defects.
- Trial name
- NCT04227964
- Testing
- Enamel matrix derivative, bone replacement graft, barrier membrane, Tooth extraction and replacement
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The European Research Group on Periodontology (ERGOPerio)
Endodontic Disease
Effect of Different Root Canal Instruments on Removal of Endotoxins From Necrotic Root Canals
Grouping: The patients will be randomly assigned into two equal groups Group : OneShape Group: ProtaperNext Endodontics procedure steps: 1.
- Trial name
- NCT03641612
- Testing
- one shape, protaper next
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heba Elasfouri
Alveolar Ridge Preservation Post-Extraction Bone Healing Dental Implant Site Development Tooth Loss
Early Dental Implant Installation in Regeneration Sites: a Prof of Concept Prospective Case Study
This study will evaluate bone healing after tooth extraction and alveolar ridge preservation, a common procedure used to maintain the bone volume needed for future dental implant placement.
- Trial name
- NCT07766057
- Testing
- Alveolar Ridge preservation and early implant placement
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Franco Cavalla
Dental Caries
The Study Aims to Compare the Effectiveness of Mesoporous Bioactive Glass-containing Adhesives vs Conventional Universal Adhesives on the Clinical Performance Composite Restorations Through Promoting Dentin Remineralization After Selective Caries Removal Over a Two-year Follow-up
a two-year, double-blind, randomized controlled trial evaluates the effectiveness of a bioactive glass adhesive (Hi-Bond Universal) versus a conventional adhesive (OptiBond Universal) in Class II carious lesions.
- Trial name
- NCT06990945
- Testing
- Hi-Bond Universal Adhesive, OptiBond Universal Adhesive
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction
Autogenous Tooth Bone Graft for Alveolar Socket Preservation
The purpose of this clinical experiment is to assess how well autogenous tooth bone grafting preserves the alveolar socket after surgical tooth extraction.
- Conditions
- Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction, Tooth Extraction Site Healing
- Trial name
- ATBG (NCT07267637)
- Testing
- "Autogenous Tooth Bone Graft"
- Where
- Yemen
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haifaa Mohammed Al-hussini
Deep Caries Lesion of Pemanent Teeth
Outcome of Selective Caries Removal Performed by Undergraduate Students
Deep tooth decay can sometimes reach very close to the nerve of a tooth. Traditionally, dentists may remove all of the decayed tooth tissue, but removing too much tissue can increase the risk of exposing or damaging the nerve.
- Trial name
- NCT07765810
- Testing
- Selective caries removal to soft dentine, Selective Caries Removal to Firm/Leathery Dentine
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Impacted Third Molar Tooth
Clinical Efficacy of a New Piezoelectric Technique for Wisdom Teeth Extraction
the aim of this randomized controlled clinical study is to evaluate the efficacy of a new piezoelectric technique for wisdom teeth extraction without using manual tools versus the conventional one.Patients referred to the…
- Trial name
- NCT03619460
- Testing
- piezoelectric extraction, conventional extraction
- Where
- Italy
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera di Bolzano
Dental Caries, Primary Teeth
Carie Care, Chemomechanical Caries Removal Technique in Primary Teeth
Chemomechanical caries removal systems have emerged as a possible valuable alternative to conventional rotary caries removal techniques in pediatric patients.
- Trial name
- NCT05538559
- Testing
- Chemomechanical caries removal by Carie-Care, Mechanical caries removal by Atraumatic Restorative Technique
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Hams Hamed Abdelrahman