Clinical trials: Tooth Disease
Dentin Hypersensitivity, Dentin Sensitivity
Study to Characterize the Efficacy of a Dual Active Dentifrice for the Relief of Dentin Hypersensitivity
This exploratory study will characterize the efficacy profile of an experimental dual active 5 percent (%) potassium nitrate/0.454% stannous fluoride dentifrice, compared to a single active 0.454% stannous fluoride desensitizing…
- Trial name
- NCT03943095
- Testing
- Potassium Nitrate, Stannous Fluoride
- Where
- Canada
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Endodontically Treated Teeth
Marginal Integrity and Clinical Evaluation of Polyetheretherketone (PEEK) Versus Lithium Disilicate (E-max) Endocrowns.
Patients need Endocrowns for their teeth usually use Emax as an etchable ceramic. Yet they have disadvantages that may influence the outcome of the endocrowns, among which is the high stiffness and rigidity owing to the higher…
- Trial name
- NCT04023357
- Testing
- PEEK, Emax
- Volunteers
- 22 people
- Sponsor
- Cairo University
Dental Caries
Clinical Evaluation of Zirconia Crowns and Anterior Strip Crowns
The hypothesis to be investigated is that no difference will be found upon comparing resin composite strip crowns and NuSmile zirconia crowns (NuSmile ZR) esthetic primary anterior in restoring anterior primary teeth.
- Trial name
- NCT03184012
- Testing
- NuSmile Zirconia crowns by NuSmile company, Composite resin strip crowns by 3M company
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Dental Caries
Checking Occlusion During Stainless Steel Crown Placement
Stainless steel crowns are arguably the most successful posterior restorations in primary teeth and have been so for more than 50 years.
- Trial name
- NCT02437565
- Testing
- Stainless steel crown, Occlusal Template
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Root Canal Infection, Pain, Postoperative
Effect of Cryotherapy and LLLT on Postoperative Pain After Root Canal Treatment
The aim of this study is to evaluate the effect of low-level laser therapy (LLLT) and intracanal cryotherapy applications on postoperative pain in endodontic interventions of primary molar teeth with apical periodontitis.
- Conditions
- Root Canal Infection, Pain, Postoperative, Cryotherapy Effect, Laser
- Trial name
- NCT05476445
- Testing
- Control, Laser, Cryotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Dental Caries
Effect of Water Rinsing After Topical Fluoride Application on Dental Plaque pH
The aim of this study was to determine whether rinsing with water or cleansing teeth after topical fluoride therapy affect the dental plaque pH.
- Trial name
- NCT01569165
- Testing
- cleansing teeth after topical fluoride therapy
- Where
- Iran
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mashhad University of Medical Sciences
Decayed Teeth, Carious Lesion
Clinical Comparison Between Stainless-steel Crown, Zirconia Crown and Bioflx Crown in Primary Molars
The purpose of this clinical trial was to compare clinically three different crowns for primary molars; stainless steel crown, zirconia crown and Bioflx crown.
- Trial name
- NCT06706167
- Testing
- stainless steel crown, Zirconia crown, Bioflx crown
- Where
- Egypt
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Delta University for Science and Technology
Pulp Necrosis, Root Canal Infection
Comparison of Ultrasonic vs 980-nm Diode Laser Irrigant Activation for Reducing Residual Bacterial DNA in Necrotic Teeth
This randomized clinical trial aimed to compare residual oral bacterial DNA detection after ultrasonic irrigant activation and 980-nm diode laser irrigant activation during root canal treatment of necrotic single-rooted teeth.
- Trial name
- NCT07607028
- Testing
- Ultrasonic Activation, 980-nm Diode Laser Activation
- Where
- Indonesia
- Volunteers
- 16 people
- Sponsor
- Hasanuddin University
Dental Plaque and Gingivitis, Oral Hygiene Reinforcement During Fixed Orthodontic Treatment
Mobile Application Push Notification in Improving Oral Hygiene Behaviour in Adolescent Orthodontic Patients
This research looks at whether using a mobile phone app that sends push-notification reminders can help adolescent orthodontic patients keep their teeth and gums cleaner during treatment.
- Trial name
- IMGS_EZGIGI (NCT07288853)
- Testing
- Ezgigi with push notification, EzGigi
- Where
- Malaysia
- Volunteers
- 78 people
- Sponsor
- Kumeran A/L Mohan
Dental Caries, Dental Fillings
SEM Evaluation of the Quantity of microRepair® on Resin Composite Surfaces: an in Vivo Randomized Clinical Trial.
The aim of this study is to evaluate the quantity of Biorepair Total Protection toothpaste on composite surfaces inside oral cavity.
- Trial name
- NCT04808557
- Testing
- Biorepair Total Protection, Sensodyne Repair & Protect
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Dentin Hypersensitivity
The Effects of Different Dentin Hypersensitivity Treatment Methods on Quality of Life
The aim of this study was to evaluate the effects of a self etch adhesive resin and two desensitizing agents(Calcium phosphate, 5% glutaraldehyde) in treatment of dentin hypersensitivity on the quality of life of individuals.
- Trial name
- NCT04887181
- Testing
- Teethmate Desensitizer, Gluma Desensitizer, Hybrid Bond
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Missing Teeth
A Proof of Concept for All-ceramic Zirconia Resin Bonded Bridges for Canine, Premolar and Short Span Posterior Teeth
Trial Design - Objectives and Purpose The aim of this study is to perform a proof of concept for the successful retention and outcome measures of zirconia RBBs for the replacement of missing canine or posterior teeth (6-8mm span)…
- Trial name
- NCT02793037
- Testing
- Zirconia resin bonded bridge
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Cross Bite, Malocclusion
Impact of Anterior Cross Bite Treatment on Children's Speech Performance
The goal of this prospective, single-arm clinical trial is to evaluate the speech performance of children with anterior dental crossbite before and after correction.
- Conditions
- Cross Bite, Malocclusion, Speech, Quality of Life
- Trial name
- NCT06168695
- Testing
- removable anterior expansion screw, Speech and language evaluation, Oral Health Related Quality of Life (OHRQoL) Assessment
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Malocclusion, Angle Class II
Effects of the Herbst Appliance With Different Anchorages and Twin-Block Appliance in Class II Malocclusion
The purpose of this study is to determine if the Herbst appliance with indirect skeletal anchorage in mini-implants is capable of preventing excessive inclination of the lower incisors at the end of the treatment when compared to…
- Trial name
- HASA (NCT02411812)
- Testing
- Herbst appliance with skeletal anchorage, Herbst appliance with dental anchorage, Twin-Block appliance
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Klaus Barretto-Lopes
Dental Caries, Reversible Pulpitis
The CAP-1 Trial: Stepwise Excavation Versus One Completed Excavation in Deep Caries
Brief summary Background: A large proportion of dental practice involves the treatment of caries in the permanent dentition. In USA alone tooth related pain is annually responsible for 15 billions days lost through sickness.
- Trial name
- NCT00187837
- Testing
- SW, DCE
- Where
- Denmark
- Volunteers
- 314 people
- Sponsor
- University of Copenhagen
Impression Technic, Dental, Jaw Relationship
Fabrication and Insertion of Michigan Splints by Dental Students
The aim of this study is to investigate the potential effects of different jaw relation determination (KRB) techniques on the fabrication of Michigan splints, in particular by comparing conventional methods with a wax plate and…
- Conditions
- Impression Technic, Dental, Jaw Relationship, Bruxism
- Trial name
- NCT06377475
- Testing
- Jaw relation, Questionnaire
- Where
- Switzerland
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Juliana Marotti Großhausen
Dental Implant Failed, Teeth Absent
Gelatin Sponge VS PTFE Membrane for Socket Sealing After Immediate Implant Placement
Digital panoramas will be made to assess the implant sites. The included patients are assigned to their respective groups randomly.
- Conditions
- Dental Implant Failed, Teeth Absent, Soft Tissue Injuries
- Trial name
- NCT05982353
- Testing
- PTFE application, Gelatin sponge
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periapical Periodontitis
Periapical Healing After One or Two-visits to Endodontic Treatment in Adolescents Patients
The main objective of this study is the prevention and repair of apical periodontitis in lower molars with pulp necrosis after the execution of endodontic treatment in one or two visits in adolescent patients.
- Trial name
- PHAP (NCT01312194)
- Testing
- Root canal therapy in one visit, Root Canal Therapy in two-vist
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dental Caries
Pre-etching of Dentin Before Restorations With High Viscosity Glass Ionomer Cement
The objective of this randomized clinical trial is to evaluate the survival of restoration with high viscosity glass ionomer cement (HVGIC) with pre-etching with polyacrilic acid compared with no pre-etching in order to treat…
- Trial name
- CEPECO4 (NCT03785769)
- Testing
- HVGIC restoration with pre-etching, HVGIC restoration with non pre-etching
- Where
- Brazil
- Volunteers
- healthy volunteers welcome
- Sponsor
- Universidade Ibirapuera
Molar-Incisor Hypomineralization (MIH)
Er:YAG Laser Versus Conventional Cavity Preparation in Children With Molar-Incisor Hypomineralization
This randomized clinical trial compares Er:YAG laser-assisted and conventional rotary cavity preparation in children aged 6-12 years with molar-incisor hypomineralization.
- Trial name
- NCT07759739
- Testing
- Er:YAG Laser-Assisted Cavity Preparation, Conventional Rotary Cavity Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ege University