Clinical trials: Tinnitus, active
Tinnitus, Misophonia
Mindfulness Application Effects on Mental Health Symptoms in Children With Severe Tinnitus and Misophonia
Children with "bothersome" tinnitus and misophonia have elevated anxiety and depression symptoms. The mainstay therapy for adults and children with these disorders is cognitive behavioral therapy (CBT).
- Trial name
- NCT06493825
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Tinnitus
Fudan Tinnitus Doctor for Tinnitus Management
The goal of this clinical trial is to evaluate whether a conversational artificial intelligence-based digital intervention can improve symptoms in adults with chronic subjective tinnitus.
- Trial name
- NCT07558837
- Testing
- Fudan Tinnitus Doctor (FTD) System, Non-conversational Digital Education Program
- Where
- China
- Volunteers
- 256 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Pulsatile Tinnitus, Venous Sinus Stenosis
BosSTENT ImpLant to trEat debilitatiNg Pulse-synchronous Tinnitus
This study is evaluating the safety and clinical performance of the BosSTENT, a new stent designed specifically for treating pulse-synchronous tinnitus due to venous sinus stenosis.
- Trial name
- B-SILENT (NCT07070089)
- Testing
- BosSTENT implantation
- Where
- 6 sites in Canada, France
- Volunteers
- 90 people
- Sponsor
- Sonorous NV, Inc
Chronic Subjective Tinnitus
Efficacy Analysis of Transcutaneous Auricular Vagus Nerve Stimulation Combined With Tailor-Made Notched Music Therapy in the Treatment of Chronic Subjective Tinnitus
The goal of this multicenter, randomized, double-blind clinical trial is to compare two treatments for adults with chronic subjective tinnitus.
- Trial name
- NCT07794462
- Testing
- taVNS Combined With TMNMT
- Where
- 6 sites in China
- Volunteers
- 444 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Tinnitus, Subjective
Neuromodulatory Effects of Audio-proprio-phonatory Reinforcement Training on Subjective Tinnitus, Demonstrated by High-density Electroencephalogram (HD EEG)
Our ecological approach to neuromodulation in the field of "acouphonology" empowers tinnitus patients to act as their own source of sound stimuli through audio-proprio-phonatory reinforcement (APPR).
- Trial name
- PHONACOU (NCT06880367)
- Testing
- The intervention is an audio-proprio-phonatory training, high-density electroencephalogram (HD-EEG)
- Where
- France
- Volunteers
- 56 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Tinnitus, Hearing Loss, Bilateral or Unilateral
Evaluating How a Tinnitus Implant Affects Tinnitus Loudness in Adults With Chronic Tinnitus and Varying Levels of Hearing Loss
This study will test an experimental Tinnitus Implant System that consists of a cochlear implant, sound processor and programming software.
- Conditions
- Tinnitus, Hearing Loss, Bilateral or Unilateral, Normal Hearing
- Trial name
- TINIS (NCT06641999)
- Testing
- Tinnitus Implant System
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 16 people
- Sponsor
- Cochlear
Tinnitus, Subjective, Cupping Therapy
Wet Cupping Therapy as an Integrative Medicine Treatment for Subjective Tinnitus
Cupping therapy is an ancient complementary medicine therapy. It was a cornerstone in many ancient healing systems, including Traditional Chinese Medicine, Unani Medicine, Traditional Korean Medicine, and Islamic Medicine.
- Trial name
- NCT07685171
- Testing
- Wet Cupping Therapy plus Usual care, usual care only
- Volunteers
- 142 people
- Sponsor
- Hamad Medical Corporation
Tinnitus, Acupuncture
Efficacy of Acupuncture on Chronic Tinnitus and Its Association With Auditory Brainstem Response Measures
The goal of this clinical trial is to learn if acupuncture works to treat chronic tinnitus in adults. It will also learn about the neurophysiological effects of acupuncture on auditory conduction pathway function.
- Conditions
- Tinnitus, Acupuncture, Auditory Brainstem Response
- Trial name
- NCT07522567
- Testing
- Acupuncture
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Sensorineural Hearing Loss, Tinnitus
Effect of a Totally Implantable Cochlear Implant on Tinnitus Severity in Adults With Preoperative Tinnitus
The purpose of this study is to investigate the degree of benefit to tinnitus symptoms by using a Totally Implantable cochlear implant (TICI) in a group of patients who have moderate-to-severe tinnitus pre-operatively.
- Trial name
- EXCITE (NCT07893860)
- Testing
- Cochlear implant
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Cochlear
Tinnitus
Peripheral-central Correlation Study on the Treatment of Chronic Tinnitus With "Dao qi Tong Luo" Based on the Theory of "Connecting the Two Ears to the Brain"
By comparing the clinical manifestations, ABR parameters and cerebral cortex blood oxygen levels of chronic tinnitus patients and healthy subjects under two different body states, the peripheral-central correlation of chronic…
- Trial name
- NCT06401993
- Testing
- The "dao qi tong luo" group, The acupuncture group
- Where
- China
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Chronic Subjective Tinnitus
Trial of Management of Chronic Tinnitus by Sound Therapy and Cognitive Behavioral Therapy
clinical trial: The main aim of this study is to compare the effectiveness of Cognitive Behavioral Therapy (CBT) and Sound Therapy, both individually and in combination, in the management of patients with chronic subjective…
- Trial name
- NCT07665385
- Testing
- Group A: sound therapy, Group B: Cognitive Behavioral Therapy, Group C: Combined CBT + Sound Therapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Sohag University
Somatosensory Tinnitus, Subjektif tınnitus
COMPARISON OF MANUAL THERAPY, TINNITUS RETRAINING THERAPY
This randomized controlled trial aims to compare the effectiveness of Manual Therapy (MT), Tinnitus Retraining Therapy (TRT), and their combination in adults with somatosensory tinnitus.
- Trial name
- TINNITUS (NCT07740954)
- Testing
- Manuel therapy
- Volunteers
- 65 people
- Sponsor
- Suleyman Demirel University
Hearing Loss, Adult-Onset, Tinnitus
AI-assisted Diagnosis, Triage and Assessment of Hearing Loss and Tinnitus
Hearing loss affects approximately 11 million people in the UK, while tinnitus impacts around 7 million. Both conditions can significantly reduce quality of life and are linked to poorer mental health and employment challenges.
- Trial name
- NCT07586098
- Testing
- Artificial Intelligence (AI) Assisted Clinical Decision Support Tool for managing Hearing Loss and Tinnitus
- Where
- United Kingdom
- Volunteers
- 1,500 people
- Sponsor
- Royal Cornwall Hospitals Trust
Tinnitus, Insomnia
Efficacy of Internet-based Cognitive Behavioral Therapy for Insomnia in Patients With Tinnitus and Insomnia
This single-center, single-blind, randomized controlled trial is designed to evaluate the efficacy of therapist-guided, internet-based cognitive behavioral therapy for insomnia (CBT-I) compared with patient education in patients…
- Trial name
- NCT07769515
- Testing
- Internet-based Cognitive Behavioral Therapy for Insomnia (CBT-I), Online Patient Education
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Tinnitus, Neural Therapy of Huneke
The Effects of Conventional Therapy on Tinnitus, Disability, and Quality of Life in Patients With Tinnitus
A randomized, single-blind, controlled trial to evaluate the effects of neural therapy on tinnitus severity, disability, and quality of life in patients with tinnitus.
- Trial name
- NCT07334002
- Testing
- Neural Therapy of Huneke, Betahistine 24 mg bid (Betaserc)
- Volunteers
- 30 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Tinnitus, Subjective, Tinnitus
Bimodal Electrical-Sound Stimulation and Auditory Training for Chronic Tonal Tinnitus
This study tests whether pairing non-invasive stimulation of the greater occipital nerve (NITESGON) with an attentionally demanding auditory frequency discrimination training task reduces tinnitus loudness and tinnitus-related…
- Conditions
- Tinnitus, Subjective, Tinnitus, Chronic Tinnitus
- Trial name
- NITESGON-ADT (NCT07393880)
- Testing
- Real NITESGON, Active Listening, Passive Listening (Control)
- Where
- Ireland
- Volunteers
- 100 people
- Sponsor
- University of Dublin, Trinity College
Tinnitus
Application of Machine Learning Based on fNIRS in Predicting Acupuncture's Efficacy in Treating Tinnitus
This trial aims to use machine learning to analyze fNIRS imaging data of specific brain regions of tinnitus patients, thereby constructing a predictive model of the clinical efficacy of acupuncture for SNT.
- Trial name
- NCT06364670
- Testing
- acupuncture
- Where
- China
- Volunteers
- 500 people
- Sponsor
- The Third Affiliated hospital of Zhejiang Chinese Medical University
Tinnitus
Manual Acupuncture for Acute Primary Tinnitus
This clinical trial aims to assess the efficacy of manual acupuncture for patients with acute primary tinnitus.
- Trial name
- NCT07515482
- Testing
- Manual acupuncture, Usaual care
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Dan Bing
Tinnitus, Noise Induced
TNF-α Treatment of Blast-Induced Tinnitus
The purpose of this multi-site research study is to determine if Etanercept, compared to a placebo, significantly reduces the severity of tinnitus (ringing in the ears) associated with history of blast and/or noise exposure or…
- Trial name
- NCT04066348
- Testing
- Etanercept, Saline
- Where
- 4 sites in United States
- Volunteers
- 88 people
- Sponsor
- Wayne State University
Head Cancer, Neck Cancer
Association Between Tinnitus and Hearing Loss in Locally Advanced Head and Neck Cancer Treated by Radiotherapy Alone or With Chemotherapy: a Prospective and Multicenter Study
The aim of the AURACCO study is to evaluate the association between the onset of tinnitus and hearing loss in patients with locally advanced head and neck cancer treated by concomitant chemoradiotherapy or exclusive radiotherapy
- Trial name
- AURACCO (NCT05946577)
- Where
- France
- Volunteers
- 140 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris