Clinical trials: Thyroidectomy
Cough Suppression, Thyroidectomy
Effects of Dexmedetomidine Combined With Lidocaine Topical Administration on Cough Reflex During Extubation in Thyroidectomy Patient.
Study Hypothesis: The combination of dexmedetomidine and lidocaine administered as laryngopharyngeal topical spray provides superior suppression of extubation cough reflex compared to lidocaine alone or placebo, without…
- Trial name
- NCT07832214
- Testing
- · Dex-Lido solution: Dexmedetomidine 100 μg/mL (concentration) was diluted with 2% lidocaine to achieve final concentration of dexmedetomidine 1 μg/kg in 5 mL total volume, · Lido solution: 2% lidocaine, 5 mL, · Control solution: 0.9% normal saline, 5 mL
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Sohag University
Laryngeal Nerve Injuries, Thyroidectomy
Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid Surgery
The frequent occurrence of impaired function in the external branch of the superior laryngeal nerves following thyroid surgery is recognized as a prevalent complication leading to a diminished quality of life.
- Conditions
- Laryngeal Nerve Injuries, Thyroidectomy, Voice Change
- Trial name
- NCT06002984
- Testing
- Using Neuromonitoring to find EBSLN
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Thyroid Carcinoma
A Study Into the Effect of Seprafilm in Open Total Thyroidectomy
The investigators intend to determine the role of Seprafilm, a popular anti-adhesive agent in minimising internal adhesion formation in the neck after thyroid surgery and therefore reduce swallowing discomfort experienced by…
- Trial name
- NCT01865838
- Testing
- Seprafilm (Sanofi, USA)
- Where
- 2 sites in Singapore
- Volunteers
- 19 people
- Sponsor
- National Cancer Centre, Singapore
Goiter
Subtotal Versus Total Thyroidectomy for Benign Goiter
The extent of thyroid resection in benign goiter is controversial. Potential advantages of TT over BST may include: one-stage removal of incidental thyroid cancer reported in up to 10% of operatively treated benign thyroid…
- Trial name
- NCT01273714
- Testing
- thyroid resection
- Where
- Poland
- Volunteers
- 8,006 people
- Sponsor
- Jagiellonian University
Thyroiditis, Postpartum
Effectiveness of Cervical Rehabilitation Program on Neck Pain, ROM and Disability After Thyroidectomy.
The aim of this research is to determine the Effects of cervical rehabilitation program on neck pain, ROM and disability after thyroidectomy. Randomized controlled trials will be done at Pakistan ordinance factory (POF) Hospital.
- Trial name
- NCT05497752
- Testing
- cervical rehabilitation program, control group
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Thyroidectomy
Use of an Oxidized Regenerated Cellulose After Thyroid Surgery: A Prospective, Randomized Study
The purpose of this study is to evaluate the effects and safety of oxidized, regenerated cellulose as an absorbable adhesion barrier after thyroidectomy.
- Trial name
- ORC (NCT01171079)
- Testing
- application of oxidized regenerated cellulose
- Where
- South Korea
- Sponsor
- Seoul National University Hospital
Thyroidectomy, Bupivacaine
Ketamine Versus Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound Guided Bilateral Superficial Cervical Plexus Block in Thyroidectomy
The aim of this study is to compare the analgesic efficacy of Dexmedetomidine and Ketamine as adjuvants to Bupivacaine in ultrasound-guided Bilateral SCPB in patients undergoing thyroidectomy
- Conditions
- Thyroidectomy, Bupivacaine, Dexmedetomidine
- Trial name
- NCT07838831
- Testing
- Group C (Control group), Group D (Dexmedetomidine group), Group K (Ketamine group)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Phoniatric Evaluation of Total Thyroidectomy
Phoniatric Evaluation and Comparison of Patients Who Underwent Sutureless Thyroidectomy With Vessel Closure Devices and Conventional Total Thyroidectomy With Suture
The purpose of this study is to compare effect of sutureless thyroidectomy with vessel closure devices and conventional thyroidectomy with suturing on voice quality with phoniatric evaluation.
- Trial name
- NCT01865006
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Istanbul University
Hypocalcemia After Total Thyroidectomy
Predicting Factors of Post-Total Thyroidectomy Hypocaӏcemia
Predicting post-total thyroidectomy hypocalcemia involves a combination of patient-specific, disease-related, and surgical factors.
- Trial name
- NCT07211581
- Testing
- total thyroidectomy
- Where
- Tunisia
- Volunteers
- 123 people
- Sponsor
- Al Safwa University College
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This is a single-site, two-component prospective study evaluating whether near-infrared autofluorescence (NIRAF) imaging can improve intraoperative identification of parathyroid glands during thyroidectomy and reduce…
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Graves Disease, Amiodarone-Induced Thyrotoxicosis
Thyroidectomy for Graves' Disease or Amiodarone-induced Thyrotoxicosis
The goal of this observational study is to learn about the potential differences in morbidity of thyroidectomy (removal of the thyroid gland) depending on the preoperative hormonal status.
- Conditions
- Graves Disease, Amiodarone-Induced Thyrotoxicosis, Thyroidectomy
- Trial name
- GRATES (NCT06963203)
- Where
- 15 sites in Belgium, France and 3 more
- Volunteers
- 486 people
- Sponsor
- Andrea Goldmann
Thyroid Diseases, Parathyroid Diseases
The Analysis of Thyroidectomy and Parathyroidectomy
To analyze surgery or not, different surgical methods, timing of surgery, and alternative managements for patients of thyroid or parathyroid disease.
- Trial name
- NCT04569513
- Testing
- Thyroid and parathyroid disease
- Where
- Taiwan
- Volunteers
- 12,000 people
- Sponsor
- National Taiwan University Hospital
Thyroidectomy, Quality of Life
Comparison of QoL for Sutureless Thyroidectomy
Patients underwent thyroidectomy filled an computer or paper based QoL questionnaire before and after operation.
- Trial name
- NCT02683551
- Testing
- Sutureless Thyroidectomy
- Volunteers
- 193 people
- Sponsor
- Istanbul University
Thyroid Neoplasm, Goiter
Total Thyroidectomy With Harmonic Scalpel®
Harmonic scalpel is a new surgical instrument. Its use has been recommended in patients submitted to total thyroidectomy. Few randomized controlled trials has been published.
- Conditions
- Thyroid Neoplasm, Goiter, Thyroid Nodule
- Trial name
- NCT00385983
- Testing
- Harmonic Scalpel
- Where
- 9 sites in Brazil
- Volunteers
- 280 people
- Sponsor
- Brazilian Society of Head and Neck Surgery
Papillary Thyroid Cancer
A Clinical Study of Transaxillary Endoscopic and Open Thyroidectomy for PTC
To evaluate the feasibility and safety of gasless transaxillary posterior endoscopic thyroidectomy (Resection of thyroid lobe and isthmus, lymph node dissection in the central area of the affected side) and open radical…
- Trial name
- NCT05545852
- Testing
- GTPET(Gasless Transaxillary Posterial Endoscopic Thyroidectomy), COT(Conventional Open Thyroidectomy)
- Where
- China
- Volunteers
- 290 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Throid Surgery, Airway Complication of Anaesthesia
Comparison of the Effects of Total Intravenous Anaesthesia With Target-Controlled Infusion (TCI) and Inhalation Anaesthesia on Airway Complications During Extubation and in the Early Postoperative Period in Thyroidectomy Surgery
Thyroid surgery is one of the most complex operations in the head and neck region due to its close relationship with anatomical structures and the high risk of recurrent laryngeal nerve injury.
- Conditions
- Throid Surgery, Airway Complication of Anaesthesia, Coughing Responses at Tracheal Extubation, Laryngospasm on Emergence
- Trial name
- NCT07325669
- Testing
- tıva
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- dilara gocmen
Block
The Perioperative Analgesic Efficiency of Bilateral Superficial Cervical Plexus Block in Patients With Thyroidectomy
To determine the postoperative analgesic efficiency of bilateral superficial plexus block, patients are divided into two groups. Study group received bilateral superficial plexus block, where control had none.
- Trial name
- NCT02680353
- Testing
- Bilateral superficial cervical plexus block
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Tokat Gaziosmanpasa University
Thyroidectomy, Education
Effect of Web-Based Training With Thyroidectomy Patients
This study evaluates the effect of an internet website, created by the nurse for the purpose of internet-based training related to perioperative period, on the anxiety and postoperative recovery measures (length of…
- Conditions
- Thyroidectomy, Education, General Surgery, Patient
- Trial name
- NCT04082845
- Testing
- Education
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Thyroid Diseases, Thyroid Cancer
Effectiveness of WeChat-Supported Neck Rehabilitation Exercises on Early Recovery After Thyroidectomy
This study aimed to evaluate the effectiveness, safety, and implementation outcomes of a WeChat mini program-supported tele-neck rehabilitation exercises for improving early postoperative neck recovery after thyroidectomy.
- Conditions
- Thyroid Diseases, Thyroid Cancer, Surgery, Postoperative Pain
- Trial name
- NCT07707401
- Testing
- WeChat-supported Neck Rehabilitation Exercise, Standardized Postoperative Care and Video Education
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai 6th People's Hospital