Clinical trials: Thyroid Pathology
Hypothyroidism, Hyperthyroidism
Brown Adipose Tissue Activity and Thyroid Hormone
Rationale: During the last decades, research in possible therapies for existing obesity and developmental factors causing obesity has explosively increased.
- Conditions
- Hypothyroidism, Hyperthyroidism, Obesity
- Trial name
- NCT02499471
- Testing
- Levothyroxine therapy (137.75 ± 23.75 μg/day)
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Maastricht University Medical Center
Pain, Postoperative, Thyroid Diseases
Postoperative Pain of Robotic, Endoscopic and Open Lateral Neck Dissection
Postoperative pain is a good indicator to confirm the advantages of the surgical methods in the era of minimally invasive surgery.
- Conditions
- Pain, Postoperative, Thyroid Diseases, Surgery
- Trial name
- NCT06803732
- Testing
- Observations on postoperative pain intensity
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai 6th People's Hospital
Laryngeal Nerve Injuries, Thyroidectomy
Effectiveness of Intraoperative Neuromonitoring of External Branch of Superior Laryngeal Nerve in Thyroid Surgery
The frequent occurrence of impaired function in the external branch of the superior laryngeal nerves following thyroid surgery is recognized as a prevalent complication leading to a diminished quality of life.
- Conditions
- Laryngeal Nerve Injuries, Thyroidectomy, Voice Change
- Trial name
- NCT06002984
- Testing
- Using Neuromonitoring to find EBSLN
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Seoul National University Hospital
Postoperative Nausea and Vomiting
The Effect of Ginger and Peppermint on Postoperative Nausea and Vomiting in Patients After Thyroid Surgery
The study was planned as a randomized controlled experimental study to determine the effect of inhalation use of ginger and peppermint on postoperative nausea and vomiting in patients undergoing thyroidectomy surgery.
- Trial name
- NCT04874298
- Testing
- Ginger, Peppermint
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Sona PASHAEI
Vocal Cord Paralysis, Recurrent Laryngeal Nerve
Effect of IONM on Efficacy and Safety Using Sugammadex in Thyroid Surgery
Thyroidectomy is a frequently performed surgeon by the head and neck and endocrine surgeons. In recent years, surgical techniques and technological developments have resulted in a significant reduction in complication rates.
- Trial name
- NCT03634956
- Testing
- Group B. Sugammadex sodium-IONM
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Hyperthyroidism, Tomography
Comparison of SUV Using SPECT/CT Between Grave's Disease Patients and Normal Humans
The purpose of this study is to find out the capacity of standardized uptake value (SUV) using single-photo emission computed tomography and computed tomography (SPECT/CT) in diagnosing Grave's Disease (hyperthyroidism).
- Conditions
- Hyperthyroidism, Tomography, Emission-Computed, Single-Photon
- Trial name
- NCT02772705
- Where
- 9 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Syncope, Bradycardia
Registry of Device Implantation
The implantable device therapy for cardiac arrhythmias has been an established therapy, and one of the common standard procedures in cardiac clinical practice.
- Conditions
- Syncope, Bradycardia, Tachycardia, Sudden Cardiac Death
- Trial name
- NCT03360227
- Testing
- implantation of cardiac devices
- Where
- Germany
- Volunteers
- 2,000 people
- Sponsor
- Klinik für Kardiologie, Pneumologie und Angiologie
Morbid Obesity, Type2diabetes
Comorbidities Resolution After MGB Surgery and Change in Body Composition
This observational study aims to learn about the correlation between the improving comorbidities associated with obesity after MGB (Mini-Gastric Bypass) surgery and changes in body composition in morbidly obese patients.
- Conditions
- Morbid Obesity, Type2diabetes, Sleep Apnea, Hypothyroidism
- Trial name
- MOGAMBO (NCT06015620)
- Testing
- Mini gastric bypass surgery
- Where
- India
- Volunteers
- 35 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Age-Related Macular Degeneration, Allergies
Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research Initiatives
To collect, preserve, and/or distribute annotated biospecimens and associated medical data to institutionally approved, investigator-directed biomedical research to discover and develop new treatments, diagnostics, and…
- Conditions
- Age-Related Macular Degeneration, Allergies, Alpha-Gal Syndrome, Alzheimer Disease
- Trial name
- NCT05635266
- Testing
- Specimen sample
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Sanguine Biosciences
Thyroid Neoplasm, Goiter
Total Thyroidectomy With Harmonic Scalpel®
Harmonic scalpel is a new surgical instrument. Its use has been recommended in patients submitted to total thyroidectomy. Few randomized controlled trials has been published.
- Conditions
- Thyroid Neoplasm, Goiter, Thyroid Nodule
- Trial name
- NCT00385983
- Testing
- Harmonic Scalpel
- Where
- 9 sites in Brazil
- Volunteers
- 280 people
- Sponsor
- Brazilian Society of Head and Neck Surgery
Thyroid Neoplasm
Validation of the Diagnostic Accuracy of the Electronic Nose in the Detection of Thyroid Cancer
Patients with a suspected thyroid nodule face an invasive and patient unfriendly diagnostic work-up to determine the risk of malignancy.
- Trial name
- NCT04883294
- Testing
- Electronic Nose
- Volunteers
- 1,500 people
- Sponsor
- Maastricht University Medical Center
Thyroid Disease, Analgesia
Effect of Bupivacaine Application on Postthyroidectomy Pain
Investigators aimed to evaluate the impact of bupivacaine administration into the surgical field after total thyroidectomy on post-operative pain and analgesic requirement with a double-blind, prospective, clinical, randomized…
- Trial name
- NCT02981095
- Testing
- Thyroidectomy, Bupivacaine, Saline Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Istanbul University
Thyroid Diseases, Thyroid Cancer
Effectiveness of WeChat-Supported Neck Rehabilitation Exercises on Early Recovery After Thyroidectomy
This study aimed to evaluate the effectiveness, safety, and implementation outcomes of a WeChat mini program-supported tele-neck rehabilitation exercises for improving early postoperative neck recovery after thyroidectomy.
- Conditions
- Thyroid Diseases, Thyroid Cancer, Surgery, Postoperative Pain
- Trial name
- NCT07707401
- Testing
- WeChat-supported Neck Rehabilitation Exercise, Standardized Postoperative Care and Video Education
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Shanghai 6th People's Hospital
Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma
Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients With Spine Metastases at Risk for Compressing the Spinal Cord
This phase II clinical trial studies how well thermal ablation and spine stereotactic radiosurgery work in treating patients with cancer that has spread to the spine (spine metastases) and is at risk for compressing the spinal…
- Conditions
- Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma, Metastatic Kidney Carcinoma, Metastatic Malignant Neoplasm in the Spine
- Trial name
- NCT02713269
- Testing
- Computed Tomography, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- M.D. Anderson Cancer Center
Obesity
Effect of Body Composition on Thyroid Hormone Levels Among Overweight and Obese Subjects
The study was aimed at investigating the relationship between body composition and thyroid hormone levels in overweight and obese subjects (BMI≥25 Kg/m2)
- Trial name
- 3/2020 (NCT04327375)
- Testing
- Observational
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Transient Hypothyroxinemia, Infant, Newborn
Thyroid Function in Term Infants With Respiratory Distress
This study was designed to evaluate the level of certain hormones (thyroid hormones and cortisol) in full term or close to full term infants who have respiratory distress severe enough to require respiratory support.
- Trial name
- NCT00293956
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Christiana Care Health Services
Weight Change, Body
Digital Lifestyle Management for Weight Loss Control After Thyroidectomy in Thyroid Cancer Patients
Thyroid hormones play an important role in the regulation of the body's metabolism. But the relationship between thyroid hormone status and the basal metabolism rate is not absolute.
- Trial name
- NCT05126706
- Testing
- Digital lifestyle management
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Seoul National University Hospital
Selenium Deficiency, Thyroid Cancer TNM Staging
Clinical Study on the Effect of Selenium Yeast Capsule on Prognosis of Differentiated Thyroid Carcinoma
Oxidative stress is involved in the pathogenesis of thyroid cancer, but the mechanism is not clear. The thyroid is the organ with the most abundant selenium content, and selenium may be involved in protecting the gland from the…
- Conditions
- Selenium Deficiency, Thyroid Cancer TNM Staging, Recurrence, Metastasis
- Trial name
- NCT04683575
- Testing
- Selenium Yeast
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Qianfoshan Hospital
Euthyroid Sick Syndromes, Septic Shock
Thyroid Hormone Supplementation in Patients With Septic Shock
The primary aim of the study would be to determine whether there is a difference in survival in the Intensive Care Unit between the group of patients with septic shock diagnosed with euthyroid sick syndrome who were treated with…
- Trial name
- NCT05270798
- Testing
- triiodothyronine
- Where
- Bosnia and Herzegovina
- Volunteers
- 108 people
- Sponsor
- Cantonal Hospital Zenica
Myocardial Infarction, Hypothyroidism
Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction(ThyroHeart-AMI)
Based on accumulating evidences showing that hypothyroid status is associated with poor prognosis among acute myocardial infarction (AMI) patients, the study is designed to evaluate whether replacement treatment with…
- Trial name
- NCT02512978
- Testing
- Levothyroxine
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital