Clinical trials: Thyroid Nodule (Benign)
Thyroid Nodule (Benign)
Ultrasound-guided Thermal Ablation for Benign Thyroid Nodules
To evaluate long-term outcomes of ultrasound-guided thermal ablation for benign thyroid nodules
- Trial name
- NCT06729762
- Testing
- ultrasound-guided thermal ablation
- Where
- China
- Volunteers
- 1,500 people
- Sponsor
- Chinese PLA General Hospital
Thyroid Nodule, Thyroid Cancer
Clinical Validation of a Molecular Signature to Detect Cancer in Thyroid Nodules With Indeterminate Cytology
1. Principal objective: The primary objective of this study is to validate the diagnostic performance of a Dx15 molecular test based on molecular transcriptomic signatures previously identified in distincts cohorts of samples to…
- Trial name
- CITHY (NCT02225509)
- Testing
- FNA biopsy for thyroid nodule(s)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Diaxonhit
Benign Thyroid Nodule
Drainless Thyroidectomy by the Sutureless Technique for Benign Thyroid Diseases
This randomized controlled trial evaluates the safety and feasibility of drainless thyroid surgery for benign thyroid diseases using a sutureless hemostatic technique.
- Trial name
- NCT07625865
- Testing
- sutureless thyroidectomy without drain, sutureless thyroidectomy with drain
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Minia University
Cancer, Thyroid
Use of an In Vivo Optical Probe to Discriminate Benign From Malignant Thyroid Nodules
This study will investigate the usefulness of an optical probe in the differentiation of thyroid cancer from normal thyroid tissue in a thyroidectomy specimen.
- Trial name
- NCT01401855
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Thyroid Nodule, Thyroid Goiter
Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System
The primary objective of this study is to reproduce in a multi-center study results obtained during the feasibility First-In-Human (FIH) study with Prof.
- Conditions
- Thyroid Nodule, Thyroid Goiter, Ablation
- Trial name
- PRECISE-BTN (NCT07287176)
- Testing
- nPulse Vybrance Percutaneous Electrode System
- Where
- 3 sites in United States
- Volunteers
- 103 people
- Sponsor
- Pulse Biosciences, Inc.
Benign Thyroid Nodule
Efficacy of a Spirulina Supplement for Amelioration of Benign ThYroid Nodules
Clinical trial with a double-blind, placebo-controlled, crossover design; enrolls approximately 30 euthyroid patients with benign thyroid nodules, who will receive for 6 weeks a spirulina-based supplement, and for another 6 weeks…
- Trial name
- ESSAY (NCT03535974)
- Testing
- Preparation with Spirulina
- Where
- Romania
- Volunteers
- 38 people
- Sponsor
- Fundatia Bio-Forum
Ablation Techniques, RFA, Ablation Treatment
Efficacy and Safety of RFA vs MWA for Treatment of Large Benign Thyroid Nodules, RCT
We conduct a multi-institutional randomized control trial of RFA and MWA for the primary treatment of large, benign nodules. Adult patients >/=18 years of age who have a solitary thyroid nodule ≥20ml in volume who presents to 1)…
- Conditions
- Ablation Techniques, RFA, Ablation Treatment, Benign Thyroid Nodules, Local Anaesthesia
- Trial name
- NCT07804862
- Testing
- Radiofrequency ablation alone, Microwave ablation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Benign Thyroid Nodules
Thermal Ablation Vs Thyroidectomy for Large Benign Thyroid Nodules
To compare the safety, efficacy and quality of life between staged thermal ablation and thyroidectomy in the treatment of Large benign thyroid nodules.
- Trial name
- NCT06607133
- Testing
- surgery, staged thermal ablation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Ming-an Yu
Thyroid Neoplasms Benign, Thyroid Nodule
Red Blood Cell Distributions (RDW, RDW-CW) and Lymphocyte Monocyte Ratios (LMR) for the Malignant Thyroid Nodules
Thyroid surgery is the most common type of surgery among endocrine surgeries. This surgery is performed for patients with suspected malignancy, patients diagnosed with malignancy, and toxic nodular goiter.
- Conditions
- Thyroid Neoplasms Benign, Thyroid Nodule, Thyroid Cancer, Thyroid Diseases
- Trial name
- NCT06283368
- Testing
- Thyroidectomy, Bilaterally Total, Thyroidectomy, Unilaterally Total, Thyroidectomy, Complementary
- Volunteers
- 172 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Benign Thyroid Nodule, Quality of Life
Alterations in Quality of Life After Thyroidectomy for Benign Thyroid Disease
To detect any changes in Quality of Life in patients with benign thyroid diseases who undergo thyroidectomy compared to patients with benign thyroid diseases and conservative treatment and healthy subjects.
- Trial name
- NCT03566537
- Testing
- Thyroidectomy
- Where
- Greece
- Volunteers
- 73 people
- Sponsor
- Aristotle University Of Thessaloniki
Hypothyroidism, Hyperthyroidism/Thyrotoxicosis
Evaluation of Different Diagnostic Therapeutic Strategies in Patients with Thyroid Pathology
Observational single-center prospective and retrospective, nonpharmacological, spontaneous cohort study.
- Conditions
- Hypothyroidism, Hyperthyroidism/Thyrotoxicosis, Thyroid Nodule (Benign), Thyroid Carcinoma
- Trial name
- NCT06779747
- Where
- Italy
- Volunteers
- 5,850 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma
Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule
This phase IV trial studies the effect of radiofrequency ablation in treating patients with benign or low risk thyroid nodule. Radiofrequency ablation uses a needle to deliver a high-frequency electric current to kill tumor cells…
- Conditions
- Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma, Thyroid Gland Follicular Tumor of Uncertain Malignant Potential, Thyroid Gland Nodule
- Trial name
- NCT05003856
- Testing
- Quality-of-Life Assessment, Radiofrequency Ablation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Thyroid Carcinoma, Thyroid Nodule (Benign)
Function Integrity of Neck Anatomy in Thyroid Surgery
Recent trends in the management of patients with low-risk papillary thyroid carcinoma who have a nonsuspicious or cytologically benign contralateral nodule call into question the need for routine total thyroidectomy.
- Conditions
- Thyroid Carcinoma, Thyroid Nodule (Benign), Ablation; Retina
- Trial name
- NCT04666103
- Testing
- Intraoperative thermal ablation
- Where
- China
- Volunteers
- 1,264 people
- Sponsor
- Wuhan University
Thyroid Nodule
Ultrasound-guided Percutaneous Microwave Ablation for Benign Thyroid Nodules
Percutaneous microwave ablation(MWA) was reported as an effective modality for the management of thyroid nodules(TNs). This study aims to validate MWA as a feasible approach for patients with TNs for whom surgery is…
- Trial name
- NCT03057925
- Testing
- Microwave Ablation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Wenjun Wu
Thyroid Cancer, Nodule Solitary Thyroid
Differentiation of Benign From Malignant Thyroid Nodules Using Diffuse Reflectance Spectroscopy
Patients with thyroid nodules are currently investigated with ultrasound with or without biopsy. Despite these investigations, a subset of patients remain "indeterminate" whereby a cancer can neither be diagnosed nor ruled out …
- Trial name
- NCT07124065
- Testing
- Diffuse reflectance spectroscopy
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- Imperial College London
Thyroid Nodules, Pulsed Field Ablation
Nanosecond Pulsed Field Ablation in the Management of Benign Thyroid Nodules
To observe the outcomes of nsPFA therapy to treat benign thyroid nodules.
- Trial name
- NCT07226804
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Thyroid Nodule (Benign)
HIFU Treatment of Benign Thyroid Nodules
This clinical trial is to evaluate the effectiveness and the safety of high intensity focused ultrasound (HIFU) in the treatment of benign thyroid nodules.
- Trial name
- NCT04233398
- Testing
- Device: Echopulse (HIFU ablation)
- Volunteers
- 240 people
- Sponsor
- Theraclion
Thyroid Nodule
Laser Ablation Versus Radiofrequency Ablation for Thyroid Nodules
The purpose of this study is to prospectively compare percutaneous radiofrequency ablation (RFA) versus percutaneous laser ablation (LA) for the treatment of solid thyroid nodules.
- Trial name
- LARA (NCT02714946)
- Testing
- Percutaneous Laser Ablation, Percutaneous Radiofrequency Ablation
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Campus Bio-Medico University
Thyroid Nodule (Benign)
US-guided RFA vs MWA in the Treatment of Benign Thyroid Nodules
To evaluate the clinical outcomes of RFA and MWA for benign thyroid nodules treatment
- Trial name
- NCT05758038
- Testing
- Radiofrequency ablation/Microwave ablation
- Volunteers
- 50 people
- Sponsor
- Assiut University
Thermal Ablation, Fine Needle Aspiration Biopsy
Ultrasound and Cytological Evaluation 3 Years After Radiofrequency Thermal Ablation of Benign Thyroid Nodules : a Prospective Exploratory Cohort of 180 Nodules
There is no scientific data on post-thermal ablation cytological aspects, but treated nodules that grow back significantly after a procedure justify a new cytology in order not to ignore a neoplastic process.
- Conditions
- Thermal Ablation, Fine Needle Aspiration Biopsy, Thyroid Nodules
- Trial name
- CYTOTHYRAF (NCT05726981)
- Testing
- Fine needle aspiration biopsy (FNAB)
- Where
- France
- Volunteers
- 85 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris