Clinical trials: Thromboelastography (TEG)
COVID-19
The Evaluation of Hemostasis in Hospitalized COVID-19 Patients
Coronavirus disease 2019 (COVID-19), a viral respiratory illness caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been shown to predispose patients to thrombotic diseases (venous and arterial) with…
- Trial name
- TARGET-COVID (NCT04493307)
- Testing
- Phlebotomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- LifeBridge Health
Peripheral Arterial Disease (PAD), Amputation
Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease
The goal of this clinical trial is to determine whether a personalised blood clot prevention plan is more effective than standard treatment in adults with peripheral artery disease (PAD) who have undergone a procedure to restore…
- Conditions
- Peripheral Arterial Disease (PAD), Amputation, Thrombosis, Thrombosis (Stent Thrombosis)
- Trial name
- NCT07613840
- Testing
- Aspirin, Clopidogrel, Ticagrelor
- Where
- 2 sites in United States
- Volunteers
- 484 people
- Sponsor
- Massachusetts General Hospital
Placenta Accreta
Use of ROTEM Intraoperatively in Women With Placenta Accreta
This study evaluates the use of rapid tests for hematocrit and clotting function in women undergoing surgery for placenta accreta.
- Trial name
- ROTEM (NCT02729974)
- Testing
- ROTEM, standard treatment
- Volunteers
- 32 people
- Sponsor
- University of Utah
Hematological Malignancies Treated With Intensive Chemotherapy
Evolution of Thromboelastography During Tranexamic Acid Treatment
Patients with hematological malignancies are at increased risk of bleeding, especially during intensive chemotherapy. The aim of this study is to compare by thromboelastography changes during the intensive chemotherapy in…
- Trial name
- TTRAP-Bleeding (NCT03801122)
- Testing
- Tranexamic acid
- Where
- France
- Volunteers
- 18 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Malignancy
Evaluation of the Effectiveness of Prophylactic LMWH by Thromboelastography
This study aims to evaluate the necessity and effectiveness of using low molecular weight heparin (LMWH) for prophylaxis in the postoperative period in patients who underwent lobectomy due to malignancy, using…
- Trial name
- NCT06484231
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people
- Sponsor
- Ege University
Hepatic Insufficiency, Blood Coagulation Disorders
Major Liver Resection: Early Clotting Disorders and Functional Impairment.
The aim of this study is to evaluate early clotting disorders through thromboelastogram and anticoagulant proteins levels (maybe also endothelial markers) and liver function by indocyanine green clearance after major liver…
- Trial name
- NCT02813538
- Testing
- Indocyanine green clearance, Thromboelastometry
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Avascular Necrosis of Femoral Head, Degenerative Arthritis of Hip
Rotational Thromboelastography Study in Tranexamic Acid and Colloid Infusion
Colloid solution is generally used to maintain intravascular volume. It is reported to impair blood coagulation in vivo and in vitro more than crystalloid does by prolonging coagulation time and decreasing clot strength.
- Trial name
- NCT02146456
- Testing
- Tranexamic Acid
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Bundang Hospital
Heart Disease, Lung Disease
Evaluating the Use of Thromboelastography (TEG) in Patient's Requiring Extracorporeal Membrane Oxygenation (ECMO)
This is a pilot study that seeks to evaluate the feasibility and safety of using a TEG algorithm in addition to traditional laboratory tests to guide transfusion and coagulation management of ECMO patients.
- Trial name
- NCT02887820
- Testing
- Thromboelastograph
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stephen Esper
Inflammatory Bowel Diseases, Thrombosis
Hypercoagulability Study Using Haemostatic Techniques in Patients With Inflammatory Bowel Disease
Descriptive study, in which the haemostatic profile of ambulatory patients with IBD will be analyzed by means of ROTEM and other techniques, such as the thrombin generation test and the study of platelet function by flow…
- Conditions
- Inflammatory Bowel Diseases, Thrombosis, Blood Coagulation Disorder
- Trial name
- EDGAR (NCT04896203)
- Testing
- rotational thromboelastometry
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Hospital Universitario La Paz
Anticoagulant Reversal, Reversal of Edoxaban Induced Anticoagulation
Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban
PER977 monotherapy and co-administration following 60 mg edoxaban will have an acceptable safety and tolerability profile with no impact on pro-coagulant biomarkers.
- Trial name
- PER977-P1 (NCT01826266)
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.
Trauma Coagulopathy
Tranexamic Acid in Patients With Traumatic Bleeding Based on Dynamic Monitoring of Thromboelastography
Trauma is an important global public health problem and is the leading cause of death in people under 40 years old. Studies have shown that early prehospital administration of TXA 1 g intravenously followed by a continuous…
- Trial name
- NCT06736860
- Testing
- Tranexamic acid (TXA) injection
- Where
- China
- Volunteers
- 580 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Liver Cirrhosis, Coagulation Disorder
Thromboelastographic Guide for Blood Products in Cirrhotics
Blood products are commonly used before invasive procedures in patients with end-stage liver diseases despite cirrhosis being a thrombophylic state.
- Trial name
- NCT02362178
- Testing
- Thromboelastography to guide blood products infusion, Standard of care coagulation tests to guide blood products infusion
- Volunteers
- 60 people
- Sponsor
- University of Modena and Reggio Emilia
Shock, Surgical, Systemic Inflammatory Response Syndrome
Thromboelastography in in Patients With Sepsis
Methods: The study is an observational prospective trial that includes 150 patients 18 or older admitted to our icu because of severe sepsis or septic shock as defined by the American College of Chest Physicians/ Society of…
- Trial name
- NCT00994877
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Surgical Blood Loss, Surgical Hemorrhage
TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss
The research team proposes a prospective, observational study to better understand how TEG can be useful in guiding clinical practice in the Main OR for subject's undergoing high transfusion risk surgeries.
- Conditions
- Surgical Blood Loss, Surgical Hemorrhage, Post Operative Hemorrhage
- Trial name
- NCT05379530
- Testing
- Thromboelastography (TEG), Anesthesia Provider Survey
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Glomerulonephritis, Membranous, Diabetic Nephropathies
The Influencing Factors and Mechanism of High Incidence of Thrombotic Events in Patients With MN and DKD
Influence factors and preliminary mechanism of high incidence of thrombotic events in patients with idiopathic membranous nephropathy and diabetes kidney disease
- Conditions
- Glomerulonephritis, Membranous, Diabetic Nephropathies, Thrombelastography, Thromboembolism
- Trial name
- NCT05656963
- Testing
- Grouping based on previous laboratory results, no intervention.
- Where
- China
- Volunteers
- 741 people
- Sponsor
- Yipeng Liu
Hip Fracture
Thromboelastography (TEG) and Clopidogrel Withdrawal Time in Elderly Patients With Hip Fracture
In the elderly patients with hip fracture, some often take antiplatelet drugs such as clopidogrel due to the ischemic cardiovascular or cerebrovascular diseases.
- Trial name
- NCT04165538
- Testing
- Thrombelastograph and surgical timing
- Volunteers
- 140 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Free Tissue Flaps
PVI Based Intraoperative Fluid Management in Head and Neck Free Flap Reconstructive Surgeries
Intraoperative fluid given according to BMI in group B and according to pulse oximeter- derived pleth variability index(MASIMO RAINBOW PULSE CO OXIMETRY) in group G.
- Trial name
- NCT03116178
- Testing
- Group G -PVI( Masimo co oximeter) guided fluid therapy, Group B- Body weight guided intravenous fluid @6-8ml/kg
- Volunteers
- 80 people
- Sponsor
- Rajiv Gandhi Cancer Institute & Research Center, India
Neuromuscular Scoliosis
Thromboelastography Transfusion Protocol for Pediatric Neuromuscular Scoliosis Surgery
The long-term goal of this study is to optimize the perioperative care of pediatric spinal deformity patients, minimizing perioperative complications and increasing cost-effectiveness of perioperative hematologic management.
- Trial name
- NCT02670798
- Testing
- Thromboelastography laboratory testing
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Washington University School of Medicine
Ischemic Stroke, Brain Hemorrhage
Prospective Analysis of the Use of TEG in Stroke Patients
The overall purpose of this study is to evaluate how effective Thromboelastography (TEG) is on identifying ischemic and hemorrhagic stroke patients at increased risk for bleeding after receiving tissue plasminogen activator…
- Trial name
- TEG (NCT02494726)
- Testing
- Thromboelastography
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Surgery
Association Between Perioperative Platelet Function and Major Adverse Perioperative Events
This study will examine the degree of blood thinning (platelet function) in patients coming for non-cardiac surgery on antiplatelet agents using platelet function tests called thromboelastography (TEG) and platelet mapping assay…
- Trial name
- NCT00901030
- Testing
- Blood drawn
- Where
- 3 sites in Canada
- Volunteers
- 250 people
- Sponsor
- McMaster University