Clinical trials: Thromboelastography
Sickle Cell Disease
Evaluating Thromboelastography (TEG) and ETP in Sickle Adults
The primary aim of this study is to investigate the reported enhanced coagulation status (prothrombotic status) in patients with sickle cell disease using 2 laboratory tests; thromboelastography (TEG) and Endogenous Thrombin…
- Trial name
- NCT02770534
- Testing
- blood test
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Acute-On-Chronic Liver Failure, Cirrhosis, Liver
Global Coagulation Assessment in Cirrhosis and ACLF
Background: Patients with cirrhosis and acute-on-chronic liver failure (ACLF) may have bleeding complications which can lead to increased mortality.
- Trial name
- NCT04332484
- Where
- India
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Heart Failure
Influence of Edoxaban on Coagulability and Thrombin Generation: An in Vitro Study Focusing on Thrombelastography
The influence of different doses of edoxaban on physical characteristics of the clot and thrombin generation kinetics in blood samples will be studied by in vitro spiking of blood samples collected from patients treated for heart…
- Trial name
- NCT02448901
- Testing
- Edoxaban
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- LifeBridge Health
Anticoagulant Reversal, Reversal of Edoxaban Induced Anticoagulation
Effects of a Double-Blind, Single Dose of PER977 Administered Alone, and Following a Single Dose of Edoxaban
PER977 monotherapy and co-administration following 60 mg edoxaban will have an acceptable safety and tolerability profile with no impact on pro-coagulant biomarkers.
- Trial name
- PER977-P1 (NCT01826266)
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Perosphere Pharmaceuticals Inc, a wholly owned subsidiary of AMAG Pharmaceuticals, Inc.
Thrombophilia
Thromboelastography to Assess Age-Related Coagulation Differences in Patients Undergoing Cesarean Delivery
The purpose of the study is to assess potential age-related differences on coagulation profile of patients undergoing Cesarean Section, using thromboelastography (TEG).
- Trial name
- NCT01416454
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Stanford University
Heart Disease, Focus is on Testing Performance of CORA Hemostasis System.
Equivalency Study of the TEG and CORA Hemostasis Systems
This study is being performed to obtain data about the CORA system, a new device that is currently being tested and is not yet cleared for sale in the United State by the Food and Drug Administration (FDA).
- Trial name
- NCT01790386
- Where
- 4 sites in United States
- Volunteers
- 465 people, healthy volunteers welcome
- Sponsor
- Coramed Technologies LLC
Blood Platelet Disorders, Cardiac Surgery
Observational Study of Platelet Dysfunction Assessed by Thromboelastography in Cardiovascular Surgery (DISPLATEG)
Perioperative bleeding requiring blood transfusion is common during cardiovascular surgery, especially in procedures requiring cardiopulmonary bypass. Adenosine diphosphate (ADP) plays a fundamental role in platelet function.
- Conditions
- Blood Platelet Disorders, Cardiac Surgery, Postoperative Bleeding
- Trial name
- DISPLATEG (NCT06961175)
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Shock, Surgical, Systemic Inflammatory Response Syndrome
Thromboelastography in in Patients With Sepsis
Methods: The study is an observational prospective trial that includes 150 patients 18 or older admitted to our icu because of severe sepsis or septic shock as defined by the American College of Chest Physicians/ Society of…
- Trial name
- NCT00994877
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Coagulopathy, Mesothelioma
Thromboelastography During Surgery for Malignant Pleural Mesothelioma
Surgery for malignant pleural mesothelioma is complex and prolonged, and may involve significant blood loss with considerable blood and product transfusion.
- Trial name
- NCT01912547
- Testing
- Blood draw for TEG analysis
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Surgical Blood Loss, Surgical Hemorrhage
TEG Use in Children Undergoing Procedures With High Anticipated Blood Loss
The research team proposes a prospective, observational study to better understand how TEG can be useful in guiding clinical practice in the Main OR for subject's undergoing high transfusion risk surgeries.
- Conditions
- Surgical Blood Loss, Surgical Hemorrhage, Post Operative Hemorrhage
- Trial name
- NCT05379530
- Testing
- Thromboelastography (TEG), Anesthesia Provider Survey
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
End Stage Renal Disease, Coagulopathy
To Compare TEG (Thrombelastography) and Conventional Tests in CKD Patients
Background: Coagulopathy in chronic kidney disease is multifactorial. Both hypocoagulopathy and hypercoaguability are seen. Conventional tests of coagulation (CCTs) end at the formation of thrombin, and do not take into account…
- Trial name
- NCT03275077
- Testing
- Thromboelastography
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institute of Liver and Biliary Sciences, India
Blood Coagulation Disorder
Palonosetron and Blood Coagulation
Palonosetron may alter whole blood coagulation. However, little is known about the dose-response relationships according to the blood concentration of palonosetron.
- Trial name
- NCT04507711
- Testing
- 0 ul of palonosetron, 1 ul of palonosetron, 10 ul of palonosetron
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Coagulation
Thromboelastography (TEG) Reference Range Study
As part of a system wide reagent verification plan Haemoscope Corporation will be running a study to verify the reference intervals of many of the reagents.
- Trial name
- NCT01357928
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Haemonetics Corporation
Thrombelastography, Acute Liver Injury, Acute Decompensation, Platelet
A Prospective Study of Application of Platelet Mapping in Chronic Liver Disease Complicated With ALI and/or AD in China
Ineffective hemostasis or a paradoxical prothrombotic state of Acute-on-chronic liver disease (ACLF) has been well established. Thrombelastography measures the dynamics of thrombin production and provides a global assessment of…
- Trial name
- NCT04675125
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Ischemic Stroke, Brain Hemorrhage
Prospective Analysis of the Use of TEG in Stroke Patients
The overall purpose of this study is to evaluate how effective Thromboelastography (TEG) is on identifying ischemic and hemorrhagic stroke patients at increased risk for bleeding after receiving tissue plasminogen activator…
- Trial name
- TEG (NCT02494726)
- Testing
- Thromboelastography
- Where
- United States
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Intrauterine Growth Restriction
Thromboelastography (TEG) In the Intrauterine Growth Restriction (IUGR) Neonatal Population by Gestational Age
The investigators aim to improve the understanding of TEG in this population in an effort to improve outcomes in a population at high risk in both the presence and absence of blood product transfusions.
- Trial name
- NCT04907578
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pit Viper Bite, Coagulopathy
Thrombelastography for Coagulopathy in Chinese Snakebites
This study aims to evaluate the coagulation disorders caused by pit viper bites in patients from Zhanjiang and surrounding areas.
- Conditions
- Pit Viper Bite, Coagulopathy, Thromboelastography (TEG), Venom-induced Consumptive Coagulopathy
- Trial name
- NCT06860503
- Where
- China
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Hansung University
Fertilization in Vitro and Blood Coagulation Factors
The Effect of In Vitro Fertilization on Coagulation Parameters as Measured by Thromboelastogram
Since its introduction in 1978, over 3.75 million babies have been born using in vitro fertilization (IVF). Maturing ovarian follicles lead to a large rise in estrogen to supra-physiological levels .
- Trial name
- NCT02503371
- Testing
- Blood coagulation anyalsis by Thromboelastogram
- Where
- Israel
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Rabin Medical Center
Blood Coagulation Disorders, Thrombotic Disorders
Determination of Fibrin Activity in Plasma on STA-R® Prototype
The purpose of the study is to give the proof of concept of the Fibrin structure assay on STA-R® prototype. It aims to identify the parameters which discriminate the pathologic from the normal population.
- Conditions
- Blood Coagulation Disorders, Thrombotic Disorders, Hemorrhagic Disorders, Trauma
- Trial name
- FAST (NCT02856789)
- Testing
- Routine hemostasis tests, Fibrin structure (FS), Thromboelastography (TEG)
- Where
- France
- Volunteers
- 913 people, healthy volunteers welcome
- Sponsor
- Diagnostica Stago R&D
Status Post Total Hip and Knee Arthroplasty
Effects of IV Tranexamic Acid on the Thromboelastogram in Patients Undergoing Total Hip or Knee Arthroplasty
Blood management is an important part of successful total joint replacement. Loss of blood and transfusion can lead to poor outcomes for patients.
- Trial name
- NCT02648295
- Testing
- Effects of IV TXA on TEG in patients undergoing THA or TKA
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- West Virginia University