Clinical trials: Third Molar Surgery
Socket Preservation
Socket Preservation After Surgical Extraction of Impacted Lower Third Molar
The aim of this study will be to evaluate socket preservation using autogenous particulate dentin in combination with liquid platelet-rich fibrin versus bone allografts and collagen cone after surgical extraction of the…
- Trial name
- NCT06716736
- Testing
- socket preservation using dentine graft mixed with i-PRF, socket preservation using bone allograft, socket preservation using collagen cone
- Where
- Egypt
- Volunteers
- 45 people
- Sponsor
- Wael Mohamed
Edema, Pain
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection.
- Conditions
- Edema, Pain, Trismus, Infection, Surgical Site
- Trial name
- NCT05466604
- Testing
- Hyaluronidase Injection mesomedica, Dexamethasone dekort
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Soft Tissue Injuries
Evaluation of the Effects of Four Different Flap Designs on Tissue Healing in Lower Third Molar Surgery
The aim of this study is to prospectively evaluate the effectiveness of 4 different flap types used during mandibular impacted wisdom teeth surgery on postoperative quality of life, soft tissue and hard tissue healing at the end…
- Trial name
- NCT06266052
- Testing
- Triangular Flap, Berwick Flap, Saurez Flap
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University
Third Molars Extraction
Effect of Post-operative Chlorhexidine on Postoperative Pain and Complications After Surgical Removal of Mandibular Third Molars
This study aimed to assess the impact of postoperative chlorhexidine use on pain management following mandibular third molar removal In this prospective, randomized controlled trial,130 patients who underwent mandibular third…
- Trial name
- RITOR (NCT06880952)
- Testing
- Chlorhexidine Digluconate Mouthwash without Alcohol
- Where
- Netherlands
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Isala
Preemptive Intravenous Ibuprofen, Intraoperative Analgesia
Impact of Preemptive Intravenous Ibuprofen on Intraoperative Analgesia in Third Molar Teeth
This study was planned to evaluate the analgesic efficacy of preemptive intravenous (iv) ibuprofen on pain occurring during and after the mandibular third molar surgeon
- Trial name
- NCT03170726
- Testing
- arveles, intrafen 800 mg, plasebos
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Erzincan University
Impacted Third Molar Tooth
Articaine and Bupivacaine in Impacted Tooth Surgery
Articaine is a common local anesthetic used in oral surgery and belongs to the amide group of it has fast onset with little side effects.
- Trial name
- NCT04645888
- Testing
- Impacted tooth surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Anxiety
Efficacy of Clonidine and Propranolol in Dentistry (AAA)
The aim of the study is to determine the efficacy of clonidine and propranolol for transient anxiety management and intra and postoperative pain in patients undergoing ambulatory surgery of third molar.
- Trial name
- NCT01784250
- Testing
- Clonidine, Propranolol
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- CES University
Third Molars Extraction
Comparative Experimental Study Between Bupivacaine and Ropivacaine Regarding Efficacy in Third Molar Removal Surgery Under General Anesthesia
The goal of this clinical trial is to compare the efficacy of bupivacaine and ropivacaine in third molar removal surgery under general anesthesia in healthy volunteers.
- Trial name
- NCT07108465
- Testing
- Bupivacaine 0,5%, Ropivacaine 0,75%
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Henrique Tedesco
Impacted Third Molar Tooth
the Effect of Ozone Oil on the Postoperative Sequalae After Surgical Removal of Third Molar
This study aimed to evaluate the effectiveness of intra socket application of Ozone oil on postoperative pain, trismus and facial swelling following the surgical extraction of impacted mandibular third molars.
- Trial name
- NCT05544539
- Testing
- Ozone-Based Agent
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Impacted Wisdom Tooth
Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin
The aim of this study was investigate the comparison of postoperative effects of local antibiotics mixed with platelet-rich fibrin and postoperative systemic antibiotic applications prescribed for mandibular impacted third molar…
- Trial name
- NCT04989127
- Testing
- Diagnosis, traditional osteotomies, Platelet Rich Fibrin
- Where
- Cyprus
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Ceren Melahat Donmezer
Third Molar Surgery
Intraosseous Versus Submucosal Dexamethsone Injection in Third Molar Surgery
The goal of this clinical trial is to learn if intraosseous dexamethasone injection is better for pain and swelling postop 3rd molar surgery than submucosal dexamethasone injection.
- Trial name
- NCT06720051
- Testing
- Intraosseous dexamethasone injection after 3rd molar surgery, Submucosal dexamethasone injection after 3rd molar surgery
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Surgical Extraction of Impacted Third Molars
The Use of Manuka Honey to Improve Healing After Third Molars Surgery
Since there is an evidence that Manuka honey is an antibacterial agent, the present study aims to confirm this characteristic and assess its effect in improving healing and reducing postsurgical symptoms, if topically applied…
- Trial name
- NCT02483741
- Testing
- Manuka Honey
- Where
- Syria
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Damascus University
Pain
Injectable Diclofenac for the Prevention of Post-operative Dental Pain
This is a prospective, randomised, double-blind, placebo-controlled, parallel group study in approximately 75 patients undergoing surgical removal of an impacted lower third molar.
- Trial name
- DP4 (NCT01706588)
- Testing
- Diclofenac sodium
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- IBSA Institut Biochimique SA
Dental Anxiety, Impacted Third Molar Tooth
Anxiety Control by Erythrina Mulungu
This study evaluated the effectiveness of the Erythrina mulungu in controlling anxiety in patients undergoing bilateral extraction of asymptomatic, impacted mandibular third molars.
- Trial name
- NCT01948622
- Testing
- Mulungu
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liane Maciel de Almeida Souza
Trismus, Edema
Investigation of the Effects of CGF and A-PRF on Pain, Edema and Trismus After Impacted Lower Third Molar Surgery
The objective of this case-control intervention study is to explore the effectiveness of Concentrated Growth Factor (CGF) and Advanced Platelet Rich Fibrin (A-PRF) on Pain, Edema and Trismus After Impacted Lower Third Molar…
- Conditions
- Trismus, Edema, Pain, Post-Op Complication
- Trial name
- NCT03690167
- Testing
- Concentrated Growth Factor (CGF), Advanced Platelet Rich Fibrin (A-PRF), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr. Damla Torul
Tooth Extraction, Molar, Third
Acupuncture on Anxiety and Inflammatory Events Following Surgery of Mandibular Third Molars
The aim of this study was to compare the effect of acupuncture and placebo acupuncture for the control of pain, edema, and trismus following the extraction of third molars and control of preoperative anxiety.
- Conditions
- Tooth Extraction, Molar, Third, Pain, Postoperative, Trismus
- Trial name
- NCT03545022
- Testing
- Acupuncture
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Facial Swelling, Pain
Effects of Low-level Laser Therapy After Surgical Removal of Impacted Lower Third Molar
Goal: The aim of this study was to evaluate the effects of low-level laser (LLL) after surgical removal of impacted lower third molars (ILTM).
- Conditions
- Facial Swelling, Pain, Trismus
- Trial name
- NCT04280809
- Testing
- GaAlAs laser
- Where
- Vietnam
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Mandibular Nerve Injury
Study on the Risk of Inferior Alveolar Nerve Damage During Lower Third Molar Surgery
Objective The present study aimed to evaluate which factors were statistically associated with a greater probability of inferior alveolar nerve (IAN) damage during lower third molar surgery.
- Trial name
- NCT04807946
- Testing
- lower third molar extraction
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Impacted Third Molar
Comparative Effects of CGF and PRP in Impacted Third Molar Surgery
This study evaluates the effects of two different blood products obtained from the patient's own blood (Concentrated Growth Factor [CGF] and Platelet-Rich Plasma [PRP]) on healing after wisdom tooth extraction.
- Trial name
- NCT07320170
- Testing
- Concentrated Growth Factor (CGF), Platelet-Rich Plasma (PRP)
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Recep Tayyip Erdogan University
Anxiety State, Pain
The Effect of Music and White Noise on Patients' Anxiety and Pain During Surgery for Impacted Mandibular Third Molar
The goal of this clinical trial is to evaluate the effect of music and whitenoise on the anxiety and pain level of patients who had impacted third molars surgery.
- Trial name
- NCT06814366
- Testing
- music and white noise intervention, music intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Alanya Alaaddin Keykubat University