Clinical trials: Terminal Illness
Illness Terminal
The Family Talk Intervention When a Parent With Dependent Children or a Child is Severely Ill
The overall aim of this study is to evaluate the effects and the implementation process of the Family Talk Intervention (FTI) in clinical practice when a child or a parent of dependent children has a…
- Trial name
- NCT05020158
- Testing
- Family Talk Intervention
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Ersta Sköndal University College
Terminal Illness
Family Talk Intervention in the Context of Specialised Palliative Home Care
This intervention study aims to evaluate a psychosocial family based intervention in clinical practice, the Family Talk Intervention (FTI), for families with dependent children affected by life-threatening/life-limiting illness…
- Trial name
- NCT05365919
- Testing
- Family Talk Intervention
- Where
- Sweden
- Volunteers
- 400 people
- Sponsor
- Ersta Sköndal University College
Advance Care Planning, Advance Directives
Project Talk Trial: Engaging Underserved Communities in End-of-life Conversations
Compared to the general population, individuals from underserved communities are more likely to receive low quality end-of-life care and unwanted, costly and burdensome treatments due in part to a lack of advance care planning…
- Conditions
- Advance Care Planning, Advance Directives, Terminal Illness, Chronic Illness
- Trial name
- NCT04612738
- Testing
- Hello (serious game), The Conversation Project (CP) Starter Kit, Table Topics (general conversation game)
- Where
- 79 sites in United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Shared Decision-Making, Quality of Life
Empowering Monterey Bay Residents for Activated, Collaborative, and Equitable Care
The purpose of the EMBRACE Study is to evaluate whether a facilitated intervention improves shared decision-making (SDM) and patient activation among low-income and minority individuals more than usual care only.
- Conditions
- Shared Decision-Making, Quality of Life, Advanced Illness, Terminal Illness
- Trial name
- EMBRACE (NCT07652359)
- Testing
- Research Assistant Support
- Where
- United States
- Volunteers
- 138 people
- Sponsor
- Stanford University
Depressive Symptoms, Depression, Anxiety
Transcranial Magnetic Stimulation for Psychological Distress in Patients With Advanced Illness
Psychological and existential distress are a common cause of suffering among patients nearing the end of life, and a major reason for requesting medical aid in dying.
- Conditions
- Depressive Symptoms, Depression, Anxiety, Psychological Distress, Terminal Illness
- Trial name
- NCT04257227
- Testing
- repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- Ottawa Hospital Research Institute
Breathlessness, Aromatherapy
Using a Fan With Aromatherapy in Breathlessness Patients in Terminal Illness
Difficulty breathing is a very devastating symptom, often seen in terminal patients. Accompanied by physical, psychological, emotional, and social limitations, Not to mention the ambiguity in the occurrence of dyspnea symptoms…
- Conditions
- Breathlessness, Aromatherapy, Fans, Terminal Illness
- Trial name
- NCT05625854
- Testing
- Blow a fan to the face combine aromatherapy, Blow a fan to the face, Blow a fan to the feet
- Where
- Taiwan
- Volunteers
- 26 people
- Sponsor
- Tsai-Wei Huang
Terminal Illness, End-of-Life Care
Non-Invasive Detection and Preservation of Neurocognitive Signals in the Peri-Death Period Using Brain-Computer Interface and Artificial Intelligence
Background: Recent electroencephalography (EEG) data indicate that the transition from clinical death to cellular death is marked by highly organized neurophysiological events, including significant surges in gamma-band power…
- Conditions
- Terminal Illness, End-of-Life Care, Death, Brain Death
- Trial name
- NeuroCogPresv (NCT07477028)
- Volunteers
- 20 people
- Sponsor
- Noah Tech, Corp.
Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke
RCT of HeartBot in Women
The goal of this clinical trial is to find out whether an app-based program called HeartBot II, which uses an artificial intelligence (AI) chatbot, can help improve women's awareness and knowledge of heart attacks in women.
- Conditions
- Participants Must be Women Aged 25 Years or Older, Participants Should Have no Self-reported History of Heart Disease or Stroke, Participants Should Have no Terminal Illness or Diagnosed Cognitive Impairment, Including Alzheimer's Disease, Participants Should Not be a Healthcare Professionals or Healthcare Trainees
- Trial name
- HeartBot II (NCT07416734)
- Testing
- HeartBot II Program, Waitlist Control
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Hospice, Psilocybin
Pilot Study of Psilocybin-Assisted Therapy for Demoralization in Patients Receiving Hospice Care
The overall objective of this study is to develop and pilot test a novel regimen of psilocybin-assisted psychotherapy for demoralization in patients receiving hospice care.
- Conditions
- Hospice, Psilocybin, Demoralization, Terminal Illness
- Trial name
- PATH (NCT04950608)
- Testing
- Psilocybin, Psychotherapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yvan Beaussant, MD, MSci
Terminal Illness, Critical Illness
Targeting Bias to Reduce Disparities in End of Life Care
This study aims to determine the ways in which clinician implicit racial biases affect clinician communication with family members of patients near the end of life and to test a novel physician training intervention to reduce the…
- Trial name
- BRiDgE-Sim (NCT05165888)
- Testing
- Communication and Bias Mitigation Training, Communication skills training
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Fever, Palliative Care
Fever In Palliative Care
The goal of this observational study is to evaluate the frequency and characteristics of fever in terminally ill adult patients admitted to the Infectious Diseases Hospice at Luigi Sacco Hospital in Milan.
- Conditions
- Fever, Palliative Care, Terminal Illness
- Trial name
- NCT07106073
- Testing
- Collection of demographic, anthropometric and clinical data.
- Where
- Italy
- Volunteers
- 145 people
- Sponsor
- Stefania Cheli
Terminal Illness, Terminal Cancer
Differences in Acceptability of Music Therapy Sessions Played Live Compared to a Recording Thereof
The present study seeks to assess differences in feasibility and acceptability of music therapy played live and listening to a recording thereof at the palliative care ward of the University Hospital Zurich.
- Trial name
- NCT06108375
- Testing
- music therapy, recording
- Where
- Switzerland
- Volunteers
- 25 people
- Sponsor
- University of Zurich
Terminal Illness, Terminal Cancer
DigiPall; a Trial of Digital Patient Reported Outcome and Biomarker Monitoring in Palliative Care
The aim of this study is to test if a system consisting of a wearable device measuring heartbeats and steps, together with daily communication with a chatbot on the smartphone asking the patients about their symptoms and giving…
- Trial name
- NCT06615349
- Testing
- DigiPall
- Where
- Switzerland
- Volunteers
- 382 people
- Sponsor
- David Blum
People with Terminal Illness
Mapping Financial Support for the Terminally Ill
People living with terminal illness (an illness that is not curable and likely to lead to death) are often unable to work and experience increased costs associated with their health, such as caring costs, needing to purchase aids…
- Trial name
- NCT06793631
- Testing
- Participants will be interviewed qualitatively about experience of providing/receiving financial support for living costs
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University College, London
Terminal Illness
Quality of Life of the Piloted Individuals and a Cost-efficiency Analysis
The increasing life expectancy and global aging population necessitate changes in long-term gerontological services based on Person-Centred Care approaches.
- Trial name
- NCT06628856
- Testing
- Quality of life
- Where
- Spain
- Volunteers
- 166 people
- Sponsor
- Universidad de Burgos
Terminal Illness
iLIVE Volunteer Study
The aim of this study is to develop and evaluate the implementation of an international volunteer training programme to support patients dying in the hospital setting and their families. It has the following objectives: 1.
- Trial name
- NCT04678310
- Testing
- Support from the hospital palliative and end of life care volunteer service (developed for this study).
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- University of Liverpool
Implantable Defibrillator User, Terminal Illness
GAMification to Encourage End-Of-Life Discussions Between ICD Patients and Caregivers
The purpose of this study is to determine the feasibility and efficacy of the GAMification to Encourage End-Of-Life (GAME-EOL) intervention, which uses the Hello Game program to encourage and facilitate quality end-of-life (EOL)…
- Trial name
- GAME-EOL (NCT04994782)
- Testing
- GAME-EOL
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Debra Moser
Neoplasms, Terminal Illness
Parenteral Nutrition Therapy in Patients With Incurable Cancer
Parenteral nutrition (PN) treatment in patients with incurable cancer is understudied and the level of evidence for clinical meaningful effects is weak.
- Trial name
- PATNIC (NCT04456647)
- Testing
- Parenteral nutrition
- Where
- 4 sites in Norway
- Volunteers
- 507 people
- Sponsor
- Norwegian University of Science and Technology
Palliative Care, Terminal Illness
'LIFEView' Audiovisual Technology: Virtual Travel to Support Wellbeing and Quality of Life at the End of Life
This study is looking to assess the use of an audio-video technology called 'LIFEView' using a laptop and large-screen TV. This tool intends to support life review or reminiscence of past experiences, escape from current…
- Conditions
- Palliative Care, Terminal Illness, Quality of Life, Psychological Distress
- Trial name
- NCT04030910
- Testing
- 'LIFEView'
- Where
- Canada
- Volunteers
- 38 people
- Sponsor
- Bruyère Health Research Institute.
Delirium, Terminal Illness
Comparing Haloperidol and Olanzapine in Treating Terminal Delirium
As patients with terminal illness enter the dying phase, they may experience symptoms of restlessness, agitation, or cognitive disturbance, known as terminal delirium.
- Trial name
- HALOLAN (NCT04750395)
- Testing
- Haloperidol Solution, Olanzapine Tablets
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- HCA Hospice Care