Clinical trials: Temporomandibular Joint Disorders
Temporomandibular Dysfunction
Traditional Chinese Medicine (TCM) for Temporomandibular Dysfunction (TMD): A Whole Systems Multi-site Trial
This study sought to evaluate the benefits of different combinations of a Self Care program, involving individually targeted education and support, plus Traditional Chinese Medicine, in terms of patients' experience and outcomes…
- Trial name
- TCM-TMD (NCT00856167)
- Testing
- Traditional Chinese Medicine, Self-care for TMD
- Volunteers
- 135 people
- Sponsor
- University of Arizona
Temporomandibular Joint Dysfunction Syndrome
Immediate Effect of Ultrasound Therapy on Bilateral Masseter Myalgia: Randomized Single Blinded Investigational Trial
Introduction. Temporomandibular disorders (TMD) are a group of conditions that are multifactorial in nature, and it primarily presents with symptoms of pain and decreased functional capacity.
- Trial name
- NCT02295644
- Testing
- Ultrasound Sonicator 740
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- State University of New York at Buffalo
Myalgia, Apnea, Obstructive Sleep
Temporomandibular Disorder (TMD) Pain in Response to Jaw Advancement in People With TMD and Obstructive Sleep Apnea
The purpose of this study is to characterize the course of temporomandibular disorder (TMD) pain in adults with TMD and obstructive sleep apnea (OSA), all of whom are being treated with mandibular advancement splint (MAS)…
- Trial name
- NCT02685202
- Testing
- Mandibular advancement splint
- Volunteers
- 9 people
- Sponsor
- University of North Carolina, Chapel Hill
Temporomandibular Joint Dysfunction Syndrome
Tailored Self-Management of Temporomandibular Disorders (TMD) Using Health Information Technology
The purpose of this pilot project is to determine the feasibility and acceptability of proposed methods for a subsequent clinical trial of a tailored self-management program (PACT) designed to decrease pain in participants with…
- Trial name
- TMDPACT (NCT03036215)
- Testing
- PACT Experimental Arm
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Stroke, Mastication Disorder
Expiratory Muscle Training in Stroke
Stroke affects the vital activities of daily living such as breathing and swallowing. After stroke excursion of the diaphragm reduces about 50%, and also the maximum expiratory pressure of the individual 50% or higher.
- Conditions
- Stroke, Mastication Disorder, Temporomandibular Disorders, Dysphagia
- Trial name
- NCT04569968
- Testing
- Expiratory muscle training
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 146 people
- Sponsor
- Abant Izzet Baysal University
Bruxism, Temporomandibular Disorders (TMD)
Short-Term Symptom Changes in Adults With Teeth Clenching or Grinding and Jaw Symptoms Receiving Splint, Botulinum Toxin, or Medication Plus Splint Care
This prospective observational study evaluated short-term patient-reported symptom changes in adults with bruxism-related and temporomandibular disorder symptoms who received one of three clinically selected management…
- Conditions
- Bruxism, Temporomandibular Disorders (TMD), Myofascial Pain
- Trial name
- NCT07586072
- Testing
- Occlusal splint, Botulinum Toxin Type A (Dysport®), Thiocolchicoside
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Recep Tayyip Erdogan University
Temporomandibular Joint Dysfunction, Pain
A Double Blind Study Comparing Hyaluronic Acid, Corticosteroid and Placebo During Arthrocentesis for Temporomandibular Joint (TMJ) Dysfunction
The purpose of this study is to determine whether the administration of hyaluronic acid or corticosteroid during arthrocentesis of the temporomandibular joint provides additional pain relief and improved function.
- Conditions
- Temporomandibular Joint Dysfunction, Pain, Arthrocentesis
- Trial name
- NCT01524913
- Testing
- Hyaluronic acid, Corticosteroid, Lactated Ringers
- Where
- 5 sites in United States
- Volunteers
- 102 people
- Sponsor
- Emory University
Temporomandibular Joint Disorders
Neurostimulation in Temporomandibular Disorders (TMD) Patients
The investigators propose to conduct a randomized blinded placebo-controlled clinical trial in patients with chronic TMD (N=20).
- Trial name
- CVS (NCT01502709)
- Testing
- Caloric Vestibular Neurostimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of North Carolina, Chapel Hill
Temporomandibular Disorder
Efficacy of Naproxen-codeine, Naproxen+Dexamethasone, and Naproxen on Myofascial Pain
Temporomandibular disorders (TMDs) are one of the most common muco-skeletal disorders, seen in the dental clinics. Many factors work together to initiate or aggravate the condition, so it is a multifactorial disorder.
- Trial name
- NCT04066426
- Testing
- naproxen sodium+codeine phosphate, naproxen sodium+dexamethasone, naproxen sodium, paracetamol
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Yuzuncu Yil University
Temporomandibular Joint Disorders
Motor Cortex as a Research & Therapeutic Target in TMD
The investigators are doing a study to learn about the effects of a type of low-energy non-surgical electrical brain stimulation (HD-tDCS) on chronic pain in people's jaw joints.
- Trial name
- NCT02247063
- Testing
- High-Definition Transcranial Direct Current Stimulation (HD-tDCS)
- Volunteers
- 24 people
- Sponsor
- University of Michigan
Temporomandibular Joint Disorders
Duloxetine for Treatment of Painful Temporomandibular Joint Disorder
Temporomandibular joint disorders (TMJD) are a family of musculoskeletal disorders that represent the most common chronic orofacial pain condition.
- Trial name
- NCT00981149
- Testing
- duloxetine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Temporomandibular Disorders
Analgesic Ointment on Temporomandibular Joint and Masticatory Muscle Pain
The purpose of this study is to compare the effectiveness of using topical cream of Ping On Ointment and using Vaseline cream in the treatment of temporomandibular joint (TMJ) and masticatory muscle pain, in order to establish…
- Trial name
- NCT00812604
- Testing
- Ping On Ointment, Vaseline
- Where
- China
- Volunteers
- 55 people
- Sponsor
- The University of Hong Kong
Temporomandibular Disorder
Effectiveness of Photobiomodulation and Manual Therapy Alone or Combined in TMD Patients
The aim of the present study was to investigate the effect of photobiomodulation (PBM) and manual therapy (MT) isolated or combined in the reduce of pain, the improve of mandibular movements, the psychosocial aspects and the…
- Trial name
- TMDPBMT (NCT03454581)
- Testing
- Photobiomodulation, Manual Therapy (MT)
- Volunteers
- 51 people
- Sponsor
- Federal University of Rio Grande do Sul
Impacted Third Molar Tooth, Temporomandibular Disorder
Assessing a New Jaw Support Device During Third Molar Extractions
During mandibular 3rd molar (wisdom tooth) extractions, when a downward force is placed on the patient's jaw, the patient must tense his/her jaw muscles to oppose it.
- Trial name
- NCT03975920
- Testing
- The Restful Jaw Device
- Where
- 4 sites in United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temporomandibular Disorders
Conservative Treatment of Patients With Temporomandibular Disorders
At any given time, 10 million Americans suffer from temporomandibular disorders (TMD), with a lifetime prevalence of 45% and costs for direct care exceeding $2 billion/year.
- Trial name
- D1P2-TMD (NCT01021306)
- Testing
- Chiropractic w/Activator & Self Care, Dental Care & Self Care, Self-Care Only Group
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Palmer College of Chiropractic
Temporomandibular Disorder
Investigation and Modulation of the Mu-opioid Mechanisms in TMD (in Vivo)
In this study, this team of researchers will investigate the impact of chronic temporomandibular disorder suffering on the endogenous μ-opioid system in vivo, arguably one of the principal endogenous pain modulatory systems in…
- Trial name
- NCT03724032
- Testing
- HD-tDCS*
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Temporomandibular Joint Dysfunction Syndrome, Burning Mouth Syndrome
Efficacy of Nalbuphine and Naloxone Administered as Nose Sprays in the Treatment of Orofacial Pain
Patients with chronic masticatory muscle pain (i.e., pain greater than three months) or patients with burning mouth syndrome participate in this study.
- Trial name
- NCT00716807
- Testing
- nalbuphine plus naloxone
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of California, San Francisco
Myofascial Pain Syndrome, Temporomandibular Disorder
The Effectiveness of a Physiotherapy Technique in Patients With Chronic Myofascial Temporomandibular Disorder
Participants with chronic orofacial pain caused by masticatory and neck muscles will be distributed in two groups, both followed with the same occlusal and self-care treatment.
- Trial name
- TrP-TMD (NCT03619889)
- Testing
- Manual pressure release technique on trigger points.
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Universidad Complutense de Madrid
Temporomandibular Disorders (TMD)
Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for Acute Treatment of Temporomandibular Disorders
The purpose of this study is to compare the efficacy and safety of rimegepant versus placebo in the acute treatment of Temporomandibular Disorders (TMD), which are medical conditions involving the temporomandibular joint (the…
- Trial name
- NCT05262517
- Testing
- Rimegepant
- Where
- 32 sites in United States
- Volunteers
- 126 people
- Sponsor
- Pfizer
Temporomandibular Joint Disorders, Orofacial Pain
Occlusal Adjustment as Treatment for Chronic Orofacial Pain
The purpose of this study is to determine whether occlusal adjustment by selective grinding and/or occlusal addition is an effective treatment of chronic temporomandibular joint disorders.
- Trial name
- NCT00899717
- Testing
- Occlusal adjustment
- Where
- 2 sites in Spain
- Volunteers
- 21 people
- Sponsor
- University of Santiago de Compostela