Clinical trials: Teeth Extraction, open to volunteers
Tooth Loss / Rehabilitation, Tooth Extraction
Ovate Pontic Versus Essix Provisional After Tooth Extraction and Alveolar Ridge Preservation (Pontic-Essix)
This randomized controlled trial compares two provisional socket-sealing concepts following single non-molar tooth extraction and alveolar ridge preservation: a fixed, tooth-supported, 3D-printed ovate pontic provisional…
- Conditions
- Tooth Loss / Rehabilitation, Tooth Extraction, Alveolar Bone Loss, Alveolar Ridge Augmentation
- Trial name
- Pontic-Essix (NCT07748871)
- Testing
- Bio-Oss Collagen, Mucograft Seal, Fixed 3D-printed ovate pontic provisional restoration
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Pain, Dental Anxiety
Effectiveness of Aromatherapy and Digital Anesthesia in Managing Dental Anxiety and Pain in Children
The goal of this clinical study is to learn whether aromatherapy and digital anesthesia are effective in reducing dental anxiety and pain during tooth extraction in children.
- Conditions
- Pain, Dental Anxiety, Tooth Extraction
- Trial name
- NCT07547371
- Testing
- Traditional Local Anesthesia (Conventional Syringe), Aromatherapy (Lavender or Orange Essential Oil), Digital Local Anesthesia (SleeperOne 5)
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Arzu Pınar Erdem
Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar
Comparison of PRF and Corticosteroids in Impacted Third Molar Surgery
This prospective, randomized interventional study aims to compare the postoperative effects of standard treatment (control), platelet-rich fibrin (PRF), and PRF combined with corticosteroid treatment in patients undergoing…
- Conditions
- Impacted Mandibular Third Molar Extraction, Impacted Lower Third Molar, Impacted Wisdom Tooth
- Trial name
- NCT07742826
- Testing
- Platelet-rich fibrin (PRF), Dexamethasone, Amoxicillin/Clavulanic Acid
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Final International University
Wound Healing and Prevention, Oral Inflammation
Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva
The intervention in this study is to determine whether multiple applications of photobiostimulation with Nd-YAG laser improve wound healing following tooth extraction and alveolar ridge preservation.
- Conditions
- Wound Healing and Prevention, Oral Inflammation, Photobiomodulation, Post-operative Pain Management
- Trial name
- NCT07095556
- Testing
- Low-level laser therapy
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Dehiscence, Tooth Extraction
Effect of Collagen Membrane on Ridge Preservation
This study will evaluate whether adding a resorbable collagen membrane to an anorganic bone-collagen composite (ABCC) graft improves ridge preservation after tooth extraction.
- Conditions
- Dehiscence, Tooth Extraction, Alveolar Bone Loss
- Trial name
- NCT07580495
- Testing
- Minimally Invasive tooth extraction, Alveolar ridge preservation with ABCC, Resorbable collagen membrane (InterCollagen® Guide)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Debora Dias
Alveolar Ridge Augmentation
PeptiCol EZgraft in the Extraction Socket Preservation Process After Tooth Extraction
This clinical trial aims to compare the efficacy and safety of applying "PeptiCol EZgraft" in extraction socket preservation procedures against "Regenomer," in terms of reducing the amount of alveolar bone change during the…
- Trial name
- NCT06783660
- Testing
- Peptide-loaded collagen sponge and collagen gel complex, Collagen sponge
- Where
- South Korea
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- NIBEC Co., Ltd.
Wisdom Tooth Removal, Antibiotic Prophylaxis
Comparison of Amoxicillin, Clindamycin and Azithromycin Single Doses Antibiotic Prophylaxis in Patient Undergoing Lower Third Molar Extraction
The goal of this clinical trial is to learn which drug amongst Amoxicillin, Clindamycin and Azithromycin single dose works better in reducing post-surgical complications in Participants getting lower wisdom teeth pulled.
- Conditions
- Wisdom Tooth Removal, Antibiotic Prophylaxis, Single Dose
- Trial name
- NCT07894016
- Testing
- Amoxicillin 2g, Clindamycin 600 mg, Azithromycin 500mg
- Volunteers
- 105 people
- Sponsor
- Dow University of Health Sciences
Dental Calculus, Gingivitis and Periodontal Diseases
Bio-Descaling Toothpaste for Dental Calculus Reduction
Dental calculus is a calcified mineralized plaque composed primarily of calcium phosphate salts covered by an unmineralized bacterial biofilm layer.
- Conditions
- Dental Calculus, Gingivitis and Periodontal Diseases, Periodontal Diseases
- Trial name
- AntiCal (NCT07689071)
- Testing
- Bio-Descaling Powder (BDP) Toothpaste
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Dental Occlusion, Occlusal Wear of Teeth
Evaluation of Occlusal Adjustment Material Removal on Monolithic Zirconia Blocks: An In Vitro Study
This study aims to improve understanding of the amount of tooth-replacement material removed during a single grinding "stroke" performed in the adjustment of a zirconia crown.
- Conditions
- Dental Occlusion, Occlusal Wear of Teeth, Fixed Dental Prosthesis
- Trial name
- NCT07280130
- Testing
- perform material removal on monolithic zirconia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Osteogenesis Imperfecta, Total Absence of Permanent Teeth
Site Preservation After Tooth Extraction
This study is mainly targeted affected teeth which could not be retained, and patients are willing to undergo implant repair at the later stage.
- Conditions
- Osteogenesis Imperfecta, Total Absence of Permanent Teeth, Tooth Socket
- Trial name
- NCT05258019
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Nanfang Hospital, Southern Medical University
Orthodontic Patients Indicated for Upper First Premolar Extraction, Orthodontic Patients Indicated for Maxillary Canine Retraction
Root Resorption and Alveolar Bone Changes in the Maxillary Canine Retraction Using Ni Ti Closed-coil Springs Versus Elastomeric Chains (A Split -Mouth Cone Beam CT Study)
This study will be carried out to asses root resorption and alveolar bone changes in the maxillary canine retraction using NiTi closed-coil springs versus elastomeric chains with cone beam CT
- Trial name
- NCT07116954
- Testing
- Twenty-Two adult Patients who indicated for bilateral maxillary first premolar extraction will be randomly assigned into two equal group., Canin retraction with NiTi Closed-Coil Springs and elastomeric chains
- Volunteers
- 22 people
- Sponsor
- Al-Azhar University
Emotional Stress
Dog-Assisted Therapy in Children During Blood or Dental Extraction.
The purpose of the present study is to evaluate the efficacy of Animal Assisted Therapy (AAT) during blood extraction or dental procedures in a Primary Care Pediatric Service.
- Trial name
- Extra-can (NCT06468111)
- Testing
- Animal Assisted Therapy
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Periodontal Defects After Third Molar Extraction, Periodontal Disease
Comparison of Autologous Tooth and Bovine Xenograft in Periodontal Healing After Mandibular Third Molar Extraction
This study investigates the healing of periodontal defects on the distal surface of the second lower molars after the surgical extraction of impacted third molars.
- Trial name
- NCT07824518
- Testing
- Autologous Tooth Graft
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Dental Pain, Sensation Disorders
Meloxicam Versus Ibuprofen for Pain Control After Third Molar Exodontia in Adult Patients
Third molar extraction is a common dental procedure, offently related with pain and swelling. The purpose of this study is to evaluate if Meloxicam has a better effect relieving pain after the extraction than Ibuprofen, one of…
- Trial name
- NCT06704113
- Testing
- meloxicam 7,5mg
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Universidad Austral de Chile
Gingival Cleft, Orthodontic Space Closure
Gingival Cleft Development at Two Time Points of Canine Retraction
The goal of this split-mouth randomized controlled trial is to assess whether the timing of extraction space closure-early vs. delayed initiation-affects the incidence of gingival cleft development in orthodontic patients.
- Trial name
- NCT07210762
- Testing
- Early space closure, Delayed space closure
- Where
- Pakistan
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Bahria University
Edentulous Jaw, Tooth Loss
Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth Sites
The placement of short implants in post-extraction sockets is a valuable option when residual bone height is limited, minimizing morbidity and treatment time.
- Conditions
- Edentulous Jaw, Tooth Loss, Toothless Mouth
- Trial name
- NCT07177521
- Testing
- Insertion of implants in post-extraction tooth
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Oral Health
Effect of Hypochlorous Acid-containing Mouthwash on Healing After Impacted Wisdom Tooth Surgery
INTRODUCTION: Local chemotherapeutic agents are used to reduce inflammation after impacted tooth extraction and to minimize possible complications, as well as to increase patient comfort.
- Trial name
- Mouthwash (NCT06920485)
- Testing
- Third molar surgery, Pain Medicine, Wound healing
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Swelling/ Edema, Trismus
The Effect of Dexamethasone Submucosal Injection After Surgical Extraction of Lower Impacted Third Molars on Trismus and Edema
This clinical trial aims to investigate whether dexamethasone decreases edema and trismus in adults undergoing lower third molar surgical extraction.
- Trial name
- NCT06953440
- Testing
- Dexamethasone Sodium Phosphate Injection
- Where
- Saudi Arabia
- Volunteers
- 66 people
- Sponsor
- King Abdulaziz University
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Pain (Visceral, Somatic, or Neuropathic)
Comparison of Conventional Buccal Nerve Block Versus Buccal Nerve Trunk Block During Extraction of Posterior Mandibular Teeth
This randomised control trial will compare the efficacy of conventional buccal nerve block versus buccal trunk block using visual analogue scale to evaluate pain and additional anesthesia injection during extraction of mandibular…
- Trial name
- Buccal Trunk (NCT07330518)
- Testing
- Conventional Buccal Nerve Block, Buccal Nerve Trunk Block
- Where
- Pakistan
- Volunteers
- 100 people
- Sponsor
- Watim Medical & Dental College