Clinical trials: Takayasu Arteritis
Takayasu Arteritis (TAK)
The Efficacy and Safety of Deucravacitinib in Takayasu's Arteritis
This is a 24-week, single-center, randomized, open-label trial conducted by Peking Union Medical College Hospital. The aim of this study is to assess the efficacy and safety of deucravacitinib in adult patients with relapsing TAK…
- Trial name
- NCT07013838
- Testing
- Deucravacitinib, Adalimumab
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chinese SLE Treatment And Research Group
Systemic Vasculitis, Arteritis, Takayasu
Study of Refractory and/or Relapsing TAkayasu aRTeritis
Takayasu arteritis (TA) is a vasculitis of unknown origin, resulting in progressive thickening and stenosis of large and medium arteries (the aorta and its major branches, and the pulmonary arteries).
- Conditions
- Systemic Vasculitis, Arteritis, Takayasu, Arteritis
- Trial name
- START (NCT03543527)
- Testing
- no intervention
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Takayasu Arteritis
Baricitinib for Refractory Takayasu Arteritis
Takayasu arteritis (TKA) is an autoimmune vasculitis characterized with involvement of aorta and its primary branches. For TKA refractory to TNF-α, Baricitinib, a reversible inhibitor of Janus kinases (JAK) family members JKA1…
- Trial name
- NCT06662721
- Testing
- Baricitinib 4 MG
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Liu Tian
Takayasu Arteritis, Pulmonary Artery Hypertension
Pulmonary Artery Involvement in Takayasu's Arteritis
The purpose of this study is to analyze the clinical manifestations, imaging features, and prognosis-related factors of pulmonary artery (PA) involvement in Takayasu's arteritis (TA), and to explore the early clinical features of…
- Trial name
- NCT03189602
- Where
- China
- Volunteers
- 51 people
- Sponsor
- Peking Union Medical College Hospital
Takayasu Arteritis
Surgery Benefits Takayasu Arteritis With Stenosis in the Descending Aorta
The long-term prognosis and optimal management for Takayasu arteritis(TA) patients with severe stenosis of the descending thoracic and abdominal aorta remain undefined.
- Trial name
- NCT07149805
- Testing
- open surgery or interventional treatment
- Volunteers
- 78 people
- Sponsor
- Peking Union Medical College Hospital
Takayasu Arteritis
Takayasu Arteritis Clinical Trial in China
To investigate the efficacy and safety of Leflunomide (LEF) versus placebo combined with prednisone for active Takayasu arteritis (TAK) in Chinese population.
- Trial name
- TACTIC (NCT02981979)
- Testing
- Leflunomide(LEF), Prednisone Acetate Tablets
- Where
- 6 sites in China
- Volunteers
- 116 people
- Sponsor
- Jiang lindi
Giant Cell Arteritis, Takayasu's Arteritis
Reproductive Health in Men and Women With Vasculitis
The purpose of this study is to learn about reproductive health, including fertility and pregnancies, in people with vasculitis.
- Conditions
- Giant Cell Arteritis, Takayasu's Arteritis, Polyarteritis Nodosa, Wegener's Granulomatosis
- Trial name
- NCT02176070
- Where
- United States
- Volunteers
- 467 people
- Sponsor
- University of South Florida
Takayasu Arteritis
Infliximab Biosimilar in Takayasu's Arteritis
Takayasu arteritis (TA) is a chronic inflammatory disease affecting large and medium caliber arteries, particularly the aortic arch and its main branches.
- Trial name
- TAKASIM (NCT03192878)
- Testing
- Infliximab
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Ospedale San Raffaele
Takayasu Arteritis
Comparison of Adalimumab and Tofacitinib in the Treatment of Active Takayasu Arteritis
This is a prospective,open-labelled,multi-center,randomized clinical trial.It compares the clinical efficacy and safety of there 2 drugs in the treatment of relapse active Takayasu's arteritis patients.
- Trial name
- ADATOFTAK (NCT05151848)
- Testing
- Adalimumab Injection, Tofacitinib 5 MG
- Where
- 4 sites in China
- Volunteers
- 100 people
- Sponsor
- Chinese SLE Treatment And Research Group
Takayasu Arteritis With Pulmonary Artery Involvement, Percutaneous Transluminal Pulmonary Angioplasty
Treatment of Patients With Takayasu Arteritis Complicated With Pulmonary Artery Involvement
1. Evaluate the effect of medical treatment and percutaneous transluminal pulmonary angioplasty on takayasu arteritis with pulmonary artery involvement 2.
- Conditions
- Takayasu Arteritis With Pulmonary Artery Involvement, Percutaneous Transluminal Pulmonary Angioplasty, PAH Targeted Medication
- Trial name
- NCT05388682
- Testing
- Percutaneous transluminal pulmonary angioplasty
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Takayasu Arteritis (TAK), Takayasu's Arteritis
Global Initiative on Takayasu Arteritis (GITA)
Takayasu's Arteritis Global Registry aims to bring a large group of patients from different parts of the world to analyse and compare the patients' demographic, clinical, laboratory, radiological and prognostic features with…
- Trial name
- GITA (NCT07558382)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Marmara University
TAKAYASU ARTERITIS
China Takayasu Arteritis Registry (CTA Registry)
Takayasu arteritis (TA) is a chronic large-vessel vasculitis that mainly affects the aorta and its major branches. The epidemiology and pathophysiology of TA is still unclear in China, although many studies have been done.
- Trial name
- NCT02964364
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Aimin Dang
Takayasu Arteritis
Drug-coated Balloon for Takayasu Arteritis Associated Renal Artery Stenosis
Takayasu arteritis associated renal artery stenosis (TARAS) is the biggest cause of hypertension in young people <40 years old. Hypertension caused by renal artery stenosis is usually hard to control in spite of two or more…
- Trial name
- NCT04137614
- Testing
- Drug coated balloon (DCB), Digital substraction angiography (DSA)
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Zhongshan Hospital
SCAD, Addison Disease
Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity
This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.
- Conditions
- SCAD, Addison Disease, Ankylosing Spondylitis, Antiphospholipid Antibody Syndrome
- Trial name
- NCT03941184
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Mayo Clinic
Behcet Disease, Antineutrophil Cytoplasmic Antibody (ANCA) Positive Vasculitis
Armenian NAtionwide REGistry of Systemic Autoimmune and Autoinflammatory Diseases
Longitudinal prospective multicenter Armenian registry of systemic autoimmune, autoinflammatory diseases with constitution of bio-banking.
- Conditions
- Behcet Disease, Antineutrophil Cytoplasmic Antibody (ANCA) Positive Vasculitis, Takayasu Arteritis, Giant Cell Arteritis
- Trial name
- NAREG (NCT05904301)
- Testing
- Usual medical management of patients, additional blood and stool samples for biobanking
- Where
- 6 sites in Armenia
- Volunteers
- 800 people
- Sponsor
- Santé Arménie French-Armenian Research Center
Takayasu Arteritis (TAK)
Monitoring Disease Activity in Patients With Takayasu Arteritis With the OMERACT Takayasu Ultrasound Score (OTUS)
This is a multicenter prospective observational study aimed at evaluating the role of an ultrasonographic score in monitoring disease activity in patients with Takayasu arteritis (TAK).
- Trial name
- MOTUS (NCT07571577)
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Takayasu's Arteritis, Giant Cell Arteritis
Carotid Artery Neovascularization in Takayasu's and Giant Cell Arteritis
The purpose of this study is to evaluate the ability of contrast enhanced carotid ultrasound to serve as an indicator of disease activity in patients with Takayasu's arteritis or Giant Cell arteritis and to determine if patients…
- Conditions
- Takayasu's Arteritis, Giant Cell Arteritis, Arteritis, Vasculitis
- Trial name
- NCT01795456
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Takayasu Arteritis
ICF in Takayasu Arteritis
The aim was to analyze the problem in patients with Takayasu Arteritis based on the International Classification of Functioning, Disability and Health.The sample of our study will consist of individuals between the ages of 18-65…
- Trial name
- NCT06289738
- Testing
- ICF
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Pamukkale University
Takayasu Arteritis
A Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's Arteritis
This study aimed to compare the efficacy and safety of a precision treatment regimen based on clinical-molecular phenotypes with a conventional treatment regimen in the treatment of patients with active Takayasu's arteritis based…
- Trial name
- NCT06498089
- Testing
- Prednisone, Methotrexate, Tocilizumab
- Where
- China
- Volunteers
- 124 people
- Sponsor
- Shanghai Zhongshan Hospital
Takayasu Arteritis, Tocilizumab
A Pilot Study in Severe Patients With Takayasu Arteritis.
Takayasu arteritis (TAK) is a rare chronic inflammatory arteritis, which lacks an effective well-accepted intervention strategy. We classify TAK patients into 3 levels, including mild, moderate, and severe.
- Conditions
- Takayasu Arteritis, Tocilizumab, Adalimumab, Treatment
- Trial name
- NCT04300686
- Testing
- Tocilizumab, Adalimumab
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Shanghai Zhongshan Hospital