Clinical trials: Tachyarrhythmia
Tachyarrhythmia, Atrial Flutter
MCG for Localization of Tachyarrhythmia's Origin
This is an exploratory research aiming to accurately identify the site of origin of tachyarrhythmia using Magnetocardiography (MCG), which will have guiding significance for early diagnosis, the formulation of treatment plans and…
- Conditions
- Tachyarrhythmia, Atrial Flutter, Paroxysmal Supraventricular Tachycardia, Atrial Tachycardia
- Trial name
- NCT06327425
- Testing
- Magnetocardiography
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Qilu Hospital of Shandong University
Atrial Fibrillation, Tachycardia
Management and Detection of Atrial Tachyarrhythmias in Patients Implanted With BIOTRONIK DX Systems
This is an observational registry study aiming to collect data on efficacy and safety of the single chamber Biotronik DX system with enhanced atrial diagnostics. The minimal follow-up period is 24 months.
- Conditions
- Atrial Fibrillation, Tachycardia, ICD Therapy, Thromboembolic Events
- Trial name
- MATRIX (NCT01774357)
- Where
- Germany
- Volunteers
- 2,054 people
- Sponsor
- Biotronik SE & Co. KG
Atrial Fibrillation (AF), Atrial Fibrillation Ablation Procedure
Efficacy and Safety of a Voltage-Guided Stepwise Strategy for Pulmonary Vein Isolation
The goal of this clinical trial is to learn if a voltage-guided stepwise pulmonary vein isolation (PVI) strategy can achieve effective PVI while potentially reducing lesion delivery, compared with conventional circumferential…
- Conditions
- Atrial Fibrillation (AF), Atrial Fibrillation Ablation Procedure, Atrial Tachyarrhythmia Recurrence, Esophageal Thermal Injury
- Trial name
- VoS-PVI (NCT07354737)
- Testing
- Radiofrequency ablation catheter system
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Ajou University School of Medicine
Tachyarrhythmias
SecuraTM ICD Clinical Evaluation Study
The purpose of the Secura clinical study is to evaluate the overall system safety and clinical performance of the Secura DR Implantable Cardioverter Defibrillator (ICD)
- Trial name
- NCT00526227
- Testing
- Secura ICD
- Where
- 13 sites in Austria, Finland and 5 more
- Volunteers
- 81 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Tachyarrhythmia, Atypical Atrial Flutter
Outcome of Induced Atypical Atrial Flutter
Background: Atypical atrial flutter (AAF) is an increasingly relevant clinical problem. Despite advancements in mapping and ablation techniques, the general management of these patients remain challenging especially when mapping…
- Conditions
- Tachyarrhythmia, Atypical Atrial Flutter, Induction of Arryhthmia, Clinical Outcome
- Trial name
- NCT06323499
- Testing
- Induction of atypical atrial flutter
- Where
- Germany
- Volunteers
- 76 people
- Sponsor
- University Hospital, Essen
Ventricular Arrhythmia, Ventricular Tachycardia (V-Tach)
Proton Radiosurgery for the Treatment of Malignant Ventricular Tachyarrhythmias
Ventricular arrhythmias (VAs) are the leading cause of sudden cardiac death (SCD) worldwide. The implantable defibrillator (ICD) increases survival in patients at risk of VA, with data of superiority to antiarrhythmic drugs.
- Trial name
- TOVEL (NCT06769451)
- Testing
- Stereotactic Arrhythmia Radioablation (STAR) with Proton Therapy
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Azienda Sanitaria Universitaria Integrata del Trentino
Tachyarrhythmia, Arrhythmias, Cardiac
Surface ECG Signal Recording for the Implantable Subcutaneous String Defibrillator (ISSD) Detection Algorithm Performance Assessment
Recorded cutaneous ECG containing arrhythmia events are separately analysed by an expert Electrophysiologist and the ISSD detection algorithm, to allow assessment of the correct detection of tachyarrhythmia events and…
- Trial name
- NCT03408951
- Testing
- Recording
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- NewPace Ltd
Heart Failure, Tachyarrhythmia
BIO|MASTER.Ilivia Family / Plexa
Post-Market Clinical Follow-up of the new Ilivia ICD Family and the new Plexa right ventricular lead to fulfill requirements by the notified body and to support regulatory approval outside of the CE region
- Trial name
- NCT02774616
- Testing
- Ilivia ICD Family, Plexa ICD lead
- Where
- 25 sites in Australia, Austria and 8 more
- Volunteers
- 292 people
- Sponsor
- Biotronik SE & Co. KG
Tachyarrhythmias, Syncope
Study of New Implantable Loop Recorder
The goal of this IDE clinical study is to evaluate the quality of the cardiac signal recordings obtained by the St. Jude Medical (SJM) Confirm Implantable Cardiac Monitor (device).
- Trial name
- NCT00746564
- Testing
- SJM Confirm
- Where
- 9 sites in United States
- Volunteers
- 75 people
- Sponsor
- Abbott Medical Devices
Atrial Tachyarrhythmia, Atrial Fibrillation
The REACT-ICD Trial
Recent advancements with implantable cardiac device technology include extensive diagnostic and therapeutic algorithms for prevention as well as termination of atrial tachyarrhythmias (ATA).
- Trial name
- REACT-ICD (NCT02439424)
- Testing
- Reactive ATP
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Hartford Hospital
Tachyarrhythmia
APART: Prevention and Automatic Therapy of Atrial Arrhythmias in Patients With Paroxysmal Supraventricular Tachycardias
The goal of APART is the assessment of the therapeutic and preventive stimulation algorithms of the Medtronic AT500 and following devices in patients with atrial tachyarrhythmias and an indication for cardiac pacing according to…
- Trial name
- NCT00170274
- Testing
- Activation of preventive and therapeutic algorithms for treatment of AF, AF Prevention and Therapy Algorithms On
- Where
- 6 sites in Germany
- Volunteers
- 156 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Cardiovascular Diseases
Management of Device Detected AT and Impact of Device Treatment Algorithms on Atrial Fibrillation
The MANDATE-AF study was designed to address evidence needs in India for device-based management of AF using AT/AF (Atrial Tachycardia/Atrial fibrillation) diagnostic features and therapies such as Reactive Atrial anti…
- Trial name
- MANDATE-AF (NCT04172883)
- Testing
- Treatment arm
- Where
- 11 sites in India
- Volunteers
- 79 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Bradycardia; Syncope, Bradyarrhythmia
Temporary Transvenous Pacemaker Placement by Intracavitary Electrocardiogram Monitoring
Traditional temporary pacing catheter insertion by intracavitary electrocardiogram (IC-ECG) monitoring which only monitoring tip polar, the negative one.
- Conditions
- Bradycardia; Syncope, Bradyarrhythmia, Brady-tachy Syndrome, Tachycardia Bradycardia
- Trial name
- NCT04905199
- Testing
- Temporary transvenous cardiac pacing
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Hunan Provincial People's Hospital
Ventricular Tachycardia, Ventricular Fibrillation
The Use of Dual Chamber ICD With Special Programmed Features to Lower the Risk of Inappropriate Shock
The RAPTURE Study will determine whether dual chamber defibrillators with atrial prevention and termination therapies, minimized ventricular pacing, and remote monitoring will reduce the rate of inappropriate shocks and improve…
- Conditions
- Ventricular Tachycardia, Ventricular Fibrillation, Atrial Fibrillation, Supraventricular Tachycardia
- Trial name
- RAPTURE (NCT00787800)
- Testing
- Dual Chamber ICD, Single Chamber ICD
- Where
- 4 sites in United States, Israel
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Arrhythmia
Study Evaluating GAP-486 on Heart Rhythm in Patients With Coronary Artery Disease
The purpose of this study is to learn the effects of a test drug on heart rhythms, which may become life-threatening if left untreated, and to provide data to see if the drug is well tolerated and safe.
- Trial name
- NCT00137332
- Testing
- GAP-486 (ZP-123), 0.9% Sodium Chloride, USP
- Where
- 33 sites in United States, Canada
- Volunteers
- 90 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Postoperative Supraventricular Tachyarrythmia
Controlled Study of ONO-1101 in Patients With Postoperative Tachyarrhythmias in Japan
The purpose of this study was to evaluate the dose-dependent effects of ONO-1101 on efficacy and safety in patients with postoperative supraventricular tachyarrhythmias.
- Trial name
- NCT00212680
- Testing
- ONO-1101
- Volunteers
- 100 people
- Sponsor
- Ono Pharma USA Inc
Congenital Heart Disease, Arrhythmia
Outcome of Ablation of Tachyarrhythmias in Patients With Congenital Heart Diseases
Our observational study aim to to evaluate the incidence of Tachyarrhythmia in patients with congenital heart diseases (corrected/non corrected) and the effectiveness of catheter ablation.RF catheter ablation was performed to all…
- Conditions
- Congenital Heart Disease, Arrhythmia, Ablation of Arrhythmias
- Trial name
- NCT07574931
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Fayoum University
Heart Disease, Implantable Cardioverter Defibrillator (ICD)
Optimal Settings for Anti Tachycardia Pacing (ATP) on ICD
This is a pragmatic, two-group, cluster randomized trial designed to compare strategies for the Anti Tachycardia Pacing (ATP)-setting in the ventricular tachyarrhythmias (VT) zone when implanting a new implantable cardioverter…
- Conditions
- Heart Disease, Implantable Cardioverter Defibrillator (ICD), Heart Rhythm Disorders, Ventricular Tachyarrhythmias
- Trial name
- DAN-ATP (NCT07354347)
- Testing
- Burst, Ramp
- Where
- Denmark
- Volunteers
- 3,980 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Arrhythmia, Quality of Life
Psychosomatic Effects of Implantable Cardioverter Defibrillator With Home Monitoring Function (QUANTUM)
Quality of life (QOL) and psychological well-being of patients with implantable cardioverter-defibrillators (ICDs) are significantly influenced by the experience of shock therapies.
- Trial name
- NCT00325221
- Testing
- HM on, HM Off
- Where
- 7 sites in Austria, Germany and 1 more
- Volunteers
- 148 people
- Sponsor
- Biotronik SE & Co. KG
Tachyarrhythmia, Heart Failure
BIO|MASTER.CorSky Family Post-market Study for the CorSky Family of ICDs
The CorSky family is BIOTRONIK´s new generation of ICDs. They are the successor devices of the current Acticor/Rivacor family and inherit all iShock/iShock_BC (Ilivia Neo, Intica Neo) implant and programmer software features.
- Trial name
- NCT07360158
- Testing
- CorSky ICD or CRT-D
- Where
- 7 sites in Austria, Czechia and 2 more
- Volunteers
- 151 people
- Sponsor
- Biotronik SE & Co. KG