Clinical trials: TIA, Brain
Transient Ischemic Attack, Cardiovascular Morbidity
Diagnosis of Transient Ischemic Attacks in the Emergency Department
Patients presenting a Transient Ischemic Attack (TIA) and admitted to the Emergency Department should be referred to a neurovascular specialist. In recent years, several hospitals have established TIA clinics.
- Trial name
- DAITSU (NCT07339787)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Strasbourg, France
Blood Pressure
Tailored Interventions to Improve Hypertension Management After Stroke or Transient Ischemic Attack (TIA)
The purpose of this study is to determine the effectiveness of interventions to improve adherence to medication and healthier lifestyle choices on blood pressure over a 6 month period in a group of people at high risk for…
- Trial name
- TIMSII (NCT01038375)
- Testing
- lifestyle counseling, home blood pressure monitoring
- Where
- 3 sites in Canada
- Volunteers
- 56 people
- Sponsor
- Hamilton Health Sciences Corporation
Stroke, Stroke (CVA) or TIA
The Imperial Comprehensive Cognitive Assessment in Cerebrovascular Disease (IC3)
Stroke is a major cause of death and disability worldwide, frequently resulting in persistent cognitive deficits among survivors.
- Conditions
- Stroke, Stroke (CVA) or TIA, Dementia, Vascular, Cerebrovascular Disorders
- Trial name
- IC3 (NCT05885295)
- Testing
- MRI brain, Blood tests, cognitive assessments
- Where
- United Kingdom
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Stroke (CVA) or TIA
Multiple Organized Systems for Engaging Stroke (MOSES)
Despite decades of national declines in stroke incidence, racial/ethnic and socioeconomic disparities in stroke prevalence and care remain pervasive and the gap in these disparities is widening.
- Trial name
- MOSES (NCT05780060)
- Testing
- Standard of care, RPM and digital feedback, Standard of care and RPM only
- Sponsor
- Montefiore Medical Center
Stroke (CVA) or TIA, Fracture
Post-Stroke Osteopathy
The sudden biomechanical inactivation, direct neuro-humoral effects and sustained systemic stress reaction, which commonly occur after stroke or TIA, all may be of relevance in triggering alterations in bone metabolism and…
- Conditions
- Stroke (CVA) or TIA, Fracture, Fall
- Trial name
- NCT04845269
- Where
- Austria
- Volunteers
- 127 people
- Sponsor
- VASCage GmbH
Ischemic Attack, Transient
Cognitive and Physical Functions in Patients With Transient Ischemic Attack. A Randomized Controlled Trial of Physical Activity on Prescription up to One Year After the Event
The purpose of this study is to determine whether Physical Activation on Prescription can help patients with TIA to become more physically active.
- Trial name
- NCT01509924
- Testing
- Physical activation on Prescription
- Where
- Sweden
- Volunteers
- 100 people
- Sponsor
- Tiohundra AB
Stroke, Transient Ischemic Attack
Copeptin for Risk Stratification in Acute Stroke Patients: the CoRisk Study
Prospective observational multicenter study to evaluate copeptin as a prognostic marker in patients with an acute cerebrovascular event.
- Trial name
- CoRisk (NCT00878813)
- Testing
- Sampling of 15ml blood, Blood-Sampling
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 1,102 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stroke, TIA, Stroke-mimics, Stroke Biomarkers
Extracellular Vesicle Surface Markers In Acute Cerebrovascular Syndromes.
Clinical implication of eventual blood biomarkers for stroke diagnosis and prognosis would be limited, mainly because clinical evaluation and scales (providing stroke severity) or neuroimaging (providing accurate size of the…
- Trial name
- ElViS-ACS (NCT06319742)
- Testing
- Extracellular vescicles (EV) analysis
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Ospedale Civico, Lugano
Stroke, Stroke (CVA) or TIA
Cawthorne-Cooksey Exercises and Frenkel Exercises on Balance and Coordination in Stroke
Stroke, often caused by cerebral circulation disruption can lead to transient or permanent brain function deficit it is a leading cause of disability and death globally, with a particularly high burden in low- and middle-income…
- Conditions
- Stroke, Stroke (CVA) or TIA, Balance, Coordination Impairment
- Trial name
- NCT07724860
- Testing
- Cawthorne-Cooksey Exercises, Frenkel Exercises
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Cardiovascular Complication, Pulmonary Embolism
MACE and PE in Elective Primary TKA & THA
This study ought to identify the occurence of the major adverse cardiovascular events (MACE) and the pumonary emoblism (PE) in patients undergoing elective primary THA \& TKA
- Conditions
- Cardiovascular Complication, Pulmonary Embolism, Stroke, Transient Ischemic Attack
- Trial name
- NCT05116280
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Thessaly
Vertebrobasilar Insufficiency, Ischemic Attack, Transient
Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke (VERiTAS)
Patients with blockage of the blood vessels that supply blood to the back of the brain, known as vertebrobasilar disease (VBD), are at risk of having a stroke or temporary symptoms of a stroke known as transient ischemic attack…
- Conditions
- Vertebrobasilar Insufficiency, Ischemic Attack, Transient, Cerebrovascular Disorder, Brain Ischemia
- Trial name
- VERiTAS (NCT00590980)
- Where
- 6 sites in United States, Canada
- Volunteers
- 82 people
- Sponsor
- University of Illinois at Chicago
Carotid Stenosis
A Prospective, Non-Randomized, Evaluation of Low-Risk Patients Undergoing Carotid Stenting With ANgiomax (Bivalirudin)
Prospective, non-randomized, single-center cohort study treating internal carotid artery stenosis using the Xact Carotid Artery Stent and emboshield distal protection system in conjunction with bivalirudin as the procedural…
- Trial name
- NCT01273350
- Testing
- Carotid PTA and stenting
- Where
- United States
- Volunteers
- 154 people
- Sponsor
- SPSI d.b.a Capital Cardiovascular Associates
Symptomatic Chronic Middle Cerebral Artery Occlusion, Infarction, Middle Cerebral Artery
Extracranial-intracranial Bypass Surgery for Symptomatic Chronic Middle Cerebral Artery Occlusion: the CMOSS-2 Trial
The CMOSS-2 trial is a government-funded, prospective, multicenter, randomized controlled trial. It will recruit symptomatic chronic occlusion of the middle cerebral artery in patients with severe hemodynamic insufficiency.
- Trial name
- NCT05899582
- Testing
- Extracranial-Intracranial Bypass Surgery, Medical treatment alone
- Where
- China
- Volunteers
- 420 people
- Sponsor
- Xuanwu Hospital, Beijing
Stroke, Stroke (CVA) or TIA
Comparative Effects of Somatosensory Stimulation and Task Based Mirror Therapy in Post Stroke Patients
This randomized controlled trial will be conducted at the Department of Physical Therapy, DHQ Hospital Sheikhupura, over duration of eleven months.
- Conditions
- Stroke, Stroke (CVA) or TIA, Upper Limb Function
- Trial name
- NCT07578844
- Testing
- Somatosensory Stimulation, Mirror Therapy:
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Acute Stroke, Transient Ischemic Attack
3 Tesla (3T) Stroke Medical Radiologic Technology (MRT) for Examining Mismatch in 1000+
The purpose of this study is to compare clinical and economic parameters of stroke patients who have received acute MRI imaging (test group) to patients who have received routine CT imaging (control group) in the clinical setting…
- Trial name
- 1000Plus (NCT00715533)
- Where
- Germany
- Volunteers
- 1,500 people
- Sponsor
- Charite University, Berlin, Germany
Ischemic Stroke, Transient Ischemic Attack
Platelet Aggregation Function-Guided De-Escalation Antiplatelet Therapy in Patients With Acute Ischemic Stroke
This multicenter, prospective, open-label, randomized controlled trial will evaluate whether platelet aggregation function-guided de-escalation of antiplatelet therapy is non-inferior in efficacy and superior in safety compared…
- Trial name
- PATH STROKE D (NCT07644234)
- Testing
- Clopidogrel, Aspirin
- Where
- China
- Volunteers
- 3,836 people
- Sponsor
- Sichuan Provincial People's Hospital
Transient Ischemic Attack (TIA)
Canadian TIA Score Versus ABCD2 Score in Risk Stratification of Transient Ischemic Attack (TIA)
This study aims to evaluate the superiority of a clinical score (Canadian TIA score) compared to the currently more widely used score in clinical practice (ABCD2 score) in stratifying the risk of stroke or carotid…
- Trial name
- NCT06718075
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Carotid Stenosis, Ischemic Stroke
Symptomatic Carotid Outcomes Registry
The purpose of this study is to build upon trials done over 30 years ago, which did not include statins, new antiplatelet agents, and newer antihypertensive medications.
- Conditions
- Carotid Stenosis, Ischemic Stroke, Transient Ischemic Attack
- Trial name
- SCORE (NCT05300737)
- Testing
- intensive medical therapy
- Where
- 18 sites in United States, Canada
- Volunteers
- 114 people
- Sponsor
- University of Maryland, Baltimore
Transient Ischemic Attack
Incidence of Paroxysmal Atrial Fibrillation (AF) in Patients With Acute Ischemic Stroke or Transient Ischemic Attacks (TIAs) by 48 Hours Holter Monitoring
200 patients presenting with symptoms of acute ischemic stroke or transient ischemic attack were included. All patients free of AF on presentation underwent 48 hours Holter monitoring within one week.
- Trial name
- NCT04679987
- Testing
- Holter ECG
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Helwan University
Cerebrovascular Accident, Transient Ischemic Attack
E-Selectin Nasal Spray to Prevent Stroke Recurrence
This study will test the safety and effectiveness of a protein called E-selectin, given as a nasal spray, in preventing the formation of blood clots that can cause stroke.
- Trial name
- NCT00012454
- Testing
- E-Selectin nasal spray
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)