StrokeNCT07578844
Comparative Effects of Somatosensory Stimulation and Task Based Mirror Therapy in Post Stroke Patients
A study testing Somatosensory Stimulation and Mirror Therapy: in people with Stroke and Stroke (CVA) or TIA, run by Riphah International University at 1 site in Pakistan.
Trial summary
This randomized controlled trial will be conducted at the Department of Physical Therapy, DHQ Hospital Sheikhupura, over duration of eleven months. A total of 20 stroke patients meeting inclusion criteria will be conveniently sampled and randomly assigned into two groups. Read more about this study
- Who is it for?
- Ages 40 to 70 years
- Conditions the study is for
- Stroke, Stroke (CVA) or TIA, Upper Limb Function
- What is being tested?
- Somatosensory Stimulation and Mirror Therapy:
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 24 participants
- Where
- 1 sitePakistan
- Study dates
- 1 Jul 2025to 1 Jul 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 70 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Age: above 40-70 years
- Both Male and female patients
- Unilateral ischemic or hemorrhagic stroke
- Having attack duration of 1 to 6 months
- Mild - Moderate motor impairment
- Moderate cognitive ability according to Mini-mental State Examination score >24 3 grade Brunnstrom upper extremity stage
Who cannot join
- Aphasia
- Serious unilateral neglect (Star Cancellation Test ≤ 44/54) or visual field deficiency
- Any other comorbid neurological diseases except for stroke
- Diagnosis of any other neuromuscular or orthopedic disease in the upper extremities
Trial locations and contacts
1 site in 1 country.
Pakistan1 site
Department of Physical Therapy, DHQ Hospital Sheikhupura
Sheikhupura
About this study
Official title: Comparative Effects of Somatosensory Stimulation and Task Based Mirror Therapy on Upper Limb Function in Post Stroke Patients
This randomized controlled trial will be conducted at the Department of Physical Therapy, DHQ Hospital Sheikhupura, over duration of eleven months. A total of 20 stroke patients meeting inclusion criteria will be conveniently sampled and randomly assigned into two groups. Group A will receive somatosensory stimulation, while Group B will undergo task-based mirror therapy. Interventions will be administered five times per week for four weeks. Upper limb function will be assessed at baseline and post-intervention using the Fugl-Meyer Assessment for Upper Extremity (FMA-UE), Action Research Arm Test (ARAT), and the Box and Block Test (BBT) to assess upper limb motor function, task based performance and gross motor dexterity. Data analysis will be performed using SPSS version 26.
- Conditions
- Stroke, Stroke (CVA) or TIA, Upper Limb Function
- Being tested
- Somatosensory Stimulation, Mirror Therapy:
- Keywords
- Mirror Therapy, Motot recovery, Stroke Rehabilitation, Somatosensory Stimulation
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Somatosensory StimulationOther
Also called somatosensory stimulation-induced rehabilitation
The group will be provided with somatosensory stimulation-induced rehabilitation of the upper limb, which will personalize to patients with both motor and sensory disturbance after stroke. The aim of the therapy will be to improve the functioning of upper limbs that focused directly on tactile, proprioceptive, and sensory discrimination abilities (14). The session will be started with a 5-minute warm-up, and the muscle groups involved active-assisted movement of the shoulder, elbow, and wrist to achieve better circulation and excite the limb to receive the sensations. Patients will be advised to direct their attention to the kinaesthetics of motion.
Mirror Therapy:Other
Patients will be administered with Task-Based Mirror Therapy, where they will practice real-life functional movement through a mirror reflection of the movement of the affected upper limb. The mirror will be located with a sagittal angle so that the reflection of the patient only display the image of the non-affected limb, resulting in an optical illusion that both limbs move symmetrically
| Study group | Role | What they receive |
|---|---|---|
| Task based Mirror Therapy | Experimental | Patients will be administered with Task-Based Mirror Therapy, where they will practice real-life functional movement through a mirror reflection of the movement of the affected upper limb. The mirror will be located with a sagittal angle so that the reflection of the patient only display the image of the non-affected limb, resulting in an optical illusion that both limbs move symmetrically Receives: Other: Mirror Therapy: |
| Somatosensory Stimulation | Experimental | The group will be provided with somatosensory stimulation-induced rehabilitation of the upper limb, which will personalize to patients with both motor and sensory disturbance after stroke. The aim of the therapy will be to improve the functioning of upper limbs that focused directly on tactile, proprioceptive, and sensory discrimination abilities (14). The session will be started with a 5-minute warm-up, and the muscle groups involved active-assisted movement of the shoulder, elbow, and wrist to achieve better circulation and excite the limb to receive the sensations. Patients will be advised to direct their attention to the kinaesthetics of motion. Receives: Other: Somatosensory Stimulation |
What is being measured
The primary outcome is the main question the study is designed to answer.
BOX & BLOCK TEST
The Box and Block Test (BBT) is a performance-based measure of gross manual dexterity that allows clinicians to infer about levels of activity
Measured: 4th Week
ACTION RESEARCH ARM TEST
Action research arm test has been used widely clinically for the assessment of upper extremity function post stroke and in various other conditions. Measurement of recovery after stroke is becoming increasingly important with the advent of new treatment options under investigation in stroke rehabilitation research.
Measured: 4th Week
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted11 May 2026
- Study start1 Jul 2025
- Primary completion1 May 2026 (estimated)
- Study completion1 Jul 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 24 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Zain Ul Abbas, Ms, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07578844
- Sponsor's protocol ID
- REC/RCR & AHS/25/0225
- Status last verified
- May 2026
- First submitted
- 5 May 2026
- Last updated
- 11 May 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 May 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Somatosensory Stimulation and Task Based Mirror Therapy on Upper Limb Function in Post Stroke Patients
- ClinicalTrials.gov ID
- NCT07578844
- Acronym / sponsor ID
- REC/RCR & AHS/25/0225
- Conditions
- Stroke, Stroke (CVA) or TIA, Upper Limb Function
- Keywords
- Mirror Therapy, Motot recovery, Stroke Rehabilitation, Somatosensory Stimulation
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 24 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 1 Jul 2025 (actual)
- Primary completion
- 1 May 2026 (estimated)
- Study completion
- 1 Jul 2026 (estimated)
- First posted
- 11 May 2026 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial will be conducted at the Department of Physical Therapy, DHQ Hospital Sheikhupura, over duration of eleven months. A total of 20 stroke patients meeting inclusion criteria will be conveniently sampled and randomly assigned into two groups. Group A will receive somatosensory stimulation, while Group B will undergo task-based mirror therapy. Interventions will be administered five times per week for four weeks. Upper limb function will be assessed at baseline and post-intervention using the Fugl-Meyer Assessment for Upper Extremity (FMA-UE), Action Research Arm Test (ARAT), and the Box and Block Test (BBT) to assess upper limb motor function, task based performance and gross motor dexterity. Data analysis will be performed using SPSS version 26.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Task based Mirror Therapy | Experimental | Other: Mirror Therapy:Patients will be administered with Task-Based Mirror Therapy, where they will practice real-life functional movement through a mirror reflection of the movement of the affected upper limb. The mirror will be located with a sagittal angle so that the reflection of the patient only display the image of the non-affected limb, resulting in an optical illusion that both limbs move symmetrically |
| Somatosensory Stimulation | Experimental | Other: Somatosensory StimulationThe group will be provided with somatosensory stimulation-induced rehabilitation of the upper limb, which will personalize to patients with both motor and sensory disturbance after stroke. The aim of the therapy will be to improve the functioning of upper limbs that focused directly on tactile, proprioceptive, and sensory discrimination abilities (14). The session will be started with a 5-minute warm-up, and the muscle groups involved active-assisted movement of the shoulder, elbow, and wrist to achieve better circulation and excite the limb to receive the sensations. Patients will be advised to direct their attention to the kinaesthetics of motion. |
Who may qualify
- Ages
- 40 to 70 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Age: above 40-70 years
- Both Male and female patients
- Unilateral ischemic or hemorrhagic stroke
- Having attack duration of 1 to 6 months
- Mild - Moderate motor impairment
Key exclusion criteria (4 listed)
- Aphasia
- Serious unilateral neglect (Star Cancellation Test ≤ 44/54) or visual field deficiency
- Any other comorbid neurological diseases except for stroke
- Diagnosis of any other neuromuscular or orthopedic disease in the upper extremities
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Somatosensory StimulationAlso: somatosensory stimulation-induced rehabilitationThe group will be provided with somatosensory stimulation-induced rehabilitation of the upper limb, which will personalize to patients with both motor and sensory disturbance after stroke. The aim of the therapy will be to improve the functioning of upper limbs that focused directly on tactile, proprioceptive, and sensory discrimination abilities (14). The session will be started with a 5-minute warm-up, and the muscle groups involved active-assisted movement of the shoulder, elbow, and wrist to achieve better circulation and excite the limb to receive the sensations. Patients will be advised to direct their attention to the kinaesthetics of motion. | Other | Somatosensory Stimulation |
| Mirror Therapy:Patients will be administered with Task-Based Mirror Therapy, where they will practice real-life functional movement through a mirror reflection of the movement of the affected upper limb. The mirror will be located with a sagittal angle so that the reflection of the patient only display the image of the non-affected limb, resulting in an optical illusion that both limbs move symmetrically | Other | Task based Mirror Therapy |
Primary outcome
BOX & BLOCK TEST
Time frame: 4th Week
The Box and Block Test (BBT) is a performance-based measure of gross manual dexterity that allows clinicians to infer about levels of activity
ACTION RESEARCH ARM TEST
Time frame: 4th Week
Action research arm test has been used widely clinically for the assessment of upper extremity function post stroke and in various other conditions. Measurement of recovery after stroke is becoming increasingly important with the advent of new treatment options under investigation in stroke rehabilitation research.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 May 2026.
- Individual participant dataSharing planned: No
Related trials for Stroke
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Temporal Interference Stimulation for Upper-Limb Motor Recovery in Early Subacute Stroke
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ELATE Study: Evaluating Large-vessel Acute Thrombectomy in Extended Time Window
Acute Ichemic Stroke
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Web-Based Tele-Rehabilitation Using Action Observation and Mirror Therapy for Subacute Stroke: A Randomized Controlled Trial
Stroke, Upper Extremity Paresis
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Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Subarachnoid Aneurysm Hemorrhage
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Selective Intra-Arterial Hypothermia After Endovascular Treatment for Acute Basilar Artery Occlusion
Acute Ischemic Stroke, Basilar Artery Occlusion
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Zain Ul Abbas, Ms principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Somatosensory Stimulation and Mirror Therapy: in people with Stroke and Stroke (CVA) or TIA, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 11 May 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
BOX & BLOCK TEST (time frame: 4th Week). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 May 2026.