Clinical trials: Symptoms Cold
Chest Tube Removal, Children
The Effects of EMLA Cream and Cold Application on Pain, Fear and Vital Signs Before Chest Tube Removal in Children
This study is being conducted to determine the effect of EMLA cream and cold application on pain, fear and vital signs before chest tube removal in children aged 7-18 years.
- Conditions
- Chest Tube Removal, Children, Pain Management
- Trial name
- NCT06913855
- Testing
- EMLA Cream, Cold application
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Istanbul Medeniyet University
Hereditary Angioedema
Social Evaluated Cold Pressor Test in Hereditary Angioedema Patients
This study aims to evaluate the differences in objective and subjective stress responses between patients with hereditary angioedema and healthy individuals to a stress-induced challenge like socially-evaluated cold pressure…
- Trial name
- FROSEN (NCT06414252)
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Labour Pain, Cold Therapy
Effect of Intermittent Heat and Cold Therapy on Comfort During Labor
Summary of the Study Childbirth is one of the most significant and complex experiences in any mother's life. According to a study, labour pain ranges from mild to severe and is felt throughout the body, particularly in the lower…
- Conditions
- Labour Pain, Cold Therapy, Heat Therapy
- Trial name
- NCT06214585
- Testing
- Intermittent heat and cold versus heat-only therapy, Heat- only Therapy
- Where
- Nepal
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Tribhuvan University, Nepal
Virus Diseases in Children
A Study to Investigate the Effect of Probiotics (Limosilactobacillus Reuteri DSM 17938 and Limosilactobacillus Reuteri DSM 33633) on Symptoms of Viral Upper Respiratory Tract Infections in Children
This study investigates the effect of Limosilactobacillus reuteri probiotic strains (DSM 17938 and DSM 33633) on symptoms of viral upper-respiratory tract infections in children.
- Trial name
- NCT07870824
- Testing
- Probiotics (L. reuteri DSM 17938 and L. reuteri DSM 33633)
- Where
- Hungary
- Volunteers
- 194 people
- Sponsor
- Milosevits Gergely
Blood Pressure, Blood Loss
LBNP Tolerance With Skin Warming After Exercise Cold Stress
Assess the effect of skin rewarming during lower body negative pressure upon arterial blood pressure and tolerance to simulated blood loss after exercise in the cold.
- Trial name
- NCT06279897
- Testing
- Skin Surface Rewarming, Skin Surface Warming, Skin Surface Heating
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Colorado Springs
URTI, Postoperative Complications
Perioperative Outcomes for Children With Preoperative URTI Symptoms After COVID-19 Pandemic
The goal of this observational study is to investigate the impact of the COVID-19 pandemic on perioperative outcomes in children with preoperative URTI symptoms and to explore whether the COVID-19 pandemic affected the additional…
- Conditions
- URTI, Postoperative Complications, COVID - 19, Elective Non-cardiac Surgery
- Trial name
- URTI (NCT07157111)
- Where
- China
- Volunteers
- 2,392 people
- Sponsor
- aijun xu
Obesity, Obesity, Abdominal
Environmental Temperature and Human White Adipose Tissue
Obesity is characterized by excessive white adipose tissue (WAT) that increases risk for disease. About 700 million adults are obese worldwide, designating the need of reducing excessive WAT in humans and subsequently the risk…
- Conditions
- Obesity, Obesity, Abdominal, Obese
- Trial name
- NCT04037371
- Testing
- Cold exposure
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Petros Dinas
Pain, Sleep
Effect of Muscle Pain in Late Cold Water Immersion, Muscular Recruitment, Postural Control Dynamic and Sleep Quality
Objective: To evaluate the effect of cold water immersion in elayed onset muscle soreness, muscle recruitment, dynamic postural control and quality of sleep in young soccer players.
- Trial name
- NCT02806609
- Testing
- Cold water immersion, with 10 degrees, for 10 minutes, immersion in water at room temperature, active recovery - running
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Breast Neoplasms
Cold Dissection Versus Electrocautery Dissection in Endoscopic Nipple-Sparing Mastectomy and Immediate Implant-Based Reconstruction: A Randomized Controlled Trial
The purpose of this study is to analyze whether cold dissection can decrease the rate of ischemia necrosis and other complications and then increase the aesthetic outcomes compared to electrocautery.
- Trial name
- NCT06024187
- Testing
- Cold dissection, Electrocautery Dissection
- Where
- China
- Volunteers
- 566 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Procedural Pain, Acute Pain
Fan-Assisted Local Cooling for Pain During Intravenous Cannulation in Adults
Inserting an intravenous (IV) cannula is one of the most frequently performed procedures in clinical practice, and it is commonly experienced as painful. Before the needle is inserted, the skin is routinely cleaned with alcohol.
- Conditions
- Procedural Pain, Acute Pain, Peripheral Intravenous Catheterization
- Trial name
- NCT07740837
- Testing
- Fan-assisted local cooling, Standard alcohol skin preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Antalya Health Sciences University
Asthma, Asthma Exacerbations
Vitamin D In the Prevention of Viral-induced Asthma in Preschoolers
In this 7-month randomized controlled trial, children aged 1 to less than 6 years, with recurrent asthma attacks triggered mostly by colds, will receive a high dose of vitamin D or a placebo every 3.5 months during their usual…
- Conditions
- Asthma, Asthma Exacerbations, Preschool Child, Vitamin D
- Trial name
- DIVA (NCT03365687)
- Testing
- Vitamin D
- Where
- 9 sites in Canada
- Volunteers
- 323 people
- Sponsor
- Professor Francine Ducharme
Asthma (Diagnosis)
The Effect of a Cold Air Eucapnic Hyperventilation Test on Lower Respiratory Airways in Healthy Volunteers and Patients With Asthma
In this study, we want to evaluate the feasibility and safety of a CAEH test in healthy volunteers and patients with asthma. We want to develop a CAEH test to differentiate patients with different types of asthma and…
- Trial name
- CLARINET (NCT07220928)
- Testing
- Cold air challenge
- Where
- Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KU Leuven
Fever
Fever Management in Children With Febrile Neutropenia
The aim of this study is to determine the effect of the cold steam application on body temperature in combination with the treatment algorithm in fever management in children with febrile neutropenia.
- Trial name
- NCT05189236
- Testing
- Control Group (Only Algorithm of Febrile Neutropenia Management), Experimental Group (Algorithm of Febrile Neutropenia Management+Cold Steam)
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Acibadem University
Postoperative Pain
The Effect of Intermittent Cryotherapy Exposure on Patients' Quality of Recovery After Surgery
"Cryotherapy", or cold therapy, can include the use of gel packs, ice bags, ice baths, whole body chambers, and cold aerosol sprays.
- Trial name
- ICE (NCT04564963)
- Testing
- Cryotherapy
- Where
- 3 sites in Canada
- Volunteers
- 196 people
- Sponsor
- Sunnybrook Health Sciences Centre
Chronic Obstructive Pulmonary Disease (COPD)
A Study to Test a Potential New Treatment for COPD Patients Suffering From the Common Cold or Influenza
The aim of the study is to assess the safety of inhaled SNG001 and the ability of inhaled SNG001 to 'switch on' the cells' anti-viral defences in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT03570359
- Testing
- Interferon Beta-1A
- Where
- 16 sites in United Kingdom
- Volunteers
- 122 people
- Sponsor
- Synairgen Research Ltd.
Cryotherapy Effect, Burn Scar
Observation of the Comfort and Efficacy of CO2 Laser Combined With Cryo 6 for Burn or Linear Scars.
To investigate the effect of 10,600 nm CO2 laser combined with Zimmer Cryo 6 forced cold air device on the comfort and efficacy of patients with burn scars or post-operative linear scars, and to provide a safer, more effective…
- Conditions
- Cryotherapy Effect, Burn Scar, Scar; Previous Cesarean Section
- Trial name
- NCT05555602
- Testing
- Cold-air cooling
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kaiyang Lv, MD-PhD
Healthy Volunteers
A Dose-Block Randomized, Placebo Controlled (Double-blind), Active Controlled(Open-label), Dose-escalation Study
The study design of this trial is a Dose-Block Randomized, Placebo controlled (Double-blind), Active Controlled(Open-label), Dose-escalation.
- Trial name
- NCT02175056
- Testing
- HL2351, Kineret(Anakinra)
- Where
- South Korea
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Handok Inc.
Common Cold, Pharyngitis
Alleviation of Common Cold Symptoms
Upper respiratory infections (URIs) have long posed a significant burden to the US healthcare system. Well before the coronavirus disease of 2019 (COVID-19) pandemic they have been among the most common acute outpatient…
- Conditions
- Common Cold, Pharyngitis, Fever, Congestion
- Trial name
- NCT06106880
- Testing
- Wintergreen Throat Spray and Aspirin Tablet
- Where
- 6 sites in United States
- Volunteers
- 157 people
- Sponsor
- Applied Biological Laboratories Inc
Hay Fever, Asthma
Evaluating the Potential of Large Language Models for Respiratory Disease Consultations
The clinical trial aimes to evaluate multiple large language models in respiratory disease consultations by comparing their performance to that of human doctors across three major medical consultation scenarios.
- Conditions
- Hay Fever, Asthma, Acute Upper Respiratory Infection, Pulmonary Embolism
- Trial name
- EPLLMMRDC (NCT06457269)
- Testing
- Diagnosis by three human doctors, Diagnosis by ChatGPT-3.5 (with search capabilities), Diagnosis by ChatGPT-3.5 (without search capabilities)
- Where
- China
- Volunteers
- 703 people
- Sponsor
- North Sichuan Medical College
Common Cold, Respiratory Tract Infections
The Effect of Zinc Acetate Lozenges on the Rate of Recovery From the Common Cold
A randomized parallel-group two arm superiority trial with an allocation ratio 1:1, both participants and investigators blinded.
- Trial name
- HelZinki (NCT03309995)
- Testing
- Lozenges
- Where
- Finland
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Helsinki