Clinical trials: Symptoms
Stress, Stress, Psychological
Simulation-based Stress Inoculation Training Study for UK Medical Professionals
This study is to assess for the effectiveness of a Simulation-Based Stress Inoculation Training (SIT) Programme for junior doctors and physicians associates.
- Conditions
- Stress, Stress, Psychological, Stress, Job
- Trial name
- SITS (NCT05182710)
- Testing
- Stress Inoculation Training, Alternative Training
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Royal Cornwall Hospitals Trust
Obesity, Obesity, Childhood
Parent-Based Intervention Following a Weight Loss Surgery
Prevention and early intervention are the most effective methods for influencing eating habits. This study helps fulfill the Department of Psychiatry's missions of clinical innovation and advancing science.
- Trial name
- PBP-B (NCT04247113)
- Testing
- Parent-based prevention following bariatric surgery
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Stanford University
Pancreatic Fistula, Distal Pancreatectomy Complications
An Evaluation of a New Technique Utilizing a Biologic Glue and Tissue Patch to Seal the Cut Edge of the Pancreas Following Removal of the Tail of the Pancreas
The purpose of this trial is to determine whether the use of an autologous falciform ligament patch combined with fibrin glue will reduce the rate of pancreatic fistula in patients completing distal pancreatectomy.
- Conditions
- Pancreatic Fistula, Distal Pancreatectomy Complications, Falciform Patch Pancreatic Closure, Fibrin Glue Pancreatic Closure
- Trial name
- NCT00889213
- Testing
- Falciform patch and fibrin glue application, standard pancreatic closure
- Where
- 2 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Sciatic Leg Pain, Hamstring Muscle Tightness
Acute Effects of Neurodynamics on Strength and Endurance in Athletes
This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population.
- Conditions
- Sciatic Leg Pain, Hamstring Muscle Tightness, Hamstring Muscle Strain, Hamstring Muscle Strength
- Trial name
- NCT07721220
- Testing
- Sciatic Slider, Sciatic Tensioner, Mechanically loaded neurodynamic sciatic floss
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- High Point University
Regional Anesthesia Morbidity, Pain, Acute
Understanding Rebound Pain After Regional Anesthesia Resolution in Healthy Volunteers
Regional anesthesia decreases postoperative pain scores and opioid consumption, and may prevent chronic pain after surgery in patients undergoing surgery.
- Conditions
- Regional Anesthesia Morbidity, Pain, Acute, Healthy
- Trial name
- NCT06005480
- Testing
- Mepivacaine
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Osteoporosis, Sarcopenia
Effectiveness of Creatine Supplementation and Exercise on Muscle and Bone
As we age, we experience a reduction in muscle and bone which inevitably decreases strength and the ability to perform tasks of daily living such as gardening, carrying groceries, and climbing stairs.
- Trial name
- NCT01057680
- Testing
- creatine monohydrate
- Where
- 2 sites in Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Bariatric Surgery, Depression
Laughter Yoga Effect Depression, Serotonin Levels With Bariatric Surgery Patient
The goal of this a quasi-trial model with pre and post-test control group is to determine the effect of laughter yoga on depression and serotonin levels in patients undergoing bariatric surgery.
- Trial name
- NCT06020079
- Testing
- laughter yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Diabete Type 2, Abdominal Obesity
Translational Study Using Human Abdominal Adipose Tissue Biopsies to Investigate the Role of Cannabinoid Receptor 1 (CB1) in Controlling Endocannabinoid and Adipokine Secretion
Abdominal obesity and type 2 diabetes are associated with the hyperactivation of the endocannabinoid system. Several animal and human studies indicate that circulating endocannabinoid (EC) levels are correlated with body fat.
- Trial name
- ENDOCATA (NCT04940962)
- Testing
- Sampling of adipose tissue
- Where
- France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Migraine Headaches
Set Point Acupuncture for Migraines Using a Digital Assistant
The object of this research study is to test a standardized set of acupuncture points on migraine patients to reduce frequency and intensity of headaches.
- Trial name
- SPAMDA (NCT00714727)
- Testing
- acupuncture
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Memorial Medical Center
Immune System, Innate Inflammatory Response
Evaluation of the Effects of Routine Intake of Fresh vs- Pasteurized Yoghurt on the Immune System in Healthy Adults
In this study, the purpose was to describe and compare the modulator effects on the immune system of the routine ingestion of fresh vs. pasteurized yoghurt.
- Trial name
- YASI-03 (NCT06263686)
- Testing
- Pasteurised yoghurt, Fresh yoghurt, Sterilised yoghurt
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Valladolid
Postoperative Pain, Cataract
Midazolam Additive to Local Anesthetic in Peribulbar Block
Regional eye blocks are usually preferred for ophthalmic procedures. Peribulbar block (PBB) is a safe alternative for patients undergoing cataract surgery.
- Conditions
- Postoperative Pain, Cataract, Local Anaesthetic Complication, Midazolam
- Trial name
- NCT03397069
- Testing
- Peribulbar block (control), Peribulbar block(M1), Peribulbar block(M2)
- Where
- Saudi Arabia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Al Jedaani Hospital
COPD, Healthy Adult
Shear Wave Elastography of Intercostal Muscles for the Non-invasive Assessment of the Work of BreathinG
Quantifying respiratory effort is a key step in physiological and clinical research on exercise tolerance, mechanisms of fatigability, and ventilatory impairment.
- Trial name
- SWING (NCT07371754)
- Testing
- Intercostal muscle shear wave elastography (SWE) during standardized inspiratory loading
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier du Havre
Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication
Red Blood Cell Transfusion in ECMO - A Feasibility Trial
Extracorporeal Membrane Oxygenation (ECMO) is an invasive and resource intense treatment used to support critically ill patients who have suffered severe cardiac arrest, cardiac failure or respiratory failure (including severe…
- Conditions
- Blood Loss Anemia, Extracorporeal Membrane Oxygenation Complication, Disability Physical, Cognitive Ability, General
- Trial name
- ROSETTA (NCT05814094)
- Testing
- Red Blood Cell Transfusion
- Where
- 2 sites in Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Overactive Bladder, Urgency Urinary Symptoms
Controlling Urgency Through Relaxation Exercises
We propose to conduct a rigorous, 12-week, randomized controlled trial of two relaxation therapies in 160 ambulatory women who report an average of at least 3 urgency-associated voiding or incontinence episodes per day.
- Conditions
- Overactive Bladder, Urgency Urinary Symptoms, Urgency Incontinence
- Trial name
- CURE (NCT02202031)
- Testing
- Paced Respiration, Music Therapy
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Acute Pain
First Evaluation of Morphine Hydrochloride by Nebulisation in Healthy Volunteers
Acute pain relief in emergency setting is still a public health priority. Pain is the primary reason for emergency room use, but the situation of "oligo-analgesia" persists in all countries.
- Trial name
- AEROMORPH1 (NCT01975753)
- Testing
- Morphine, Fentanyl
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Quality of Recovery, Pain, Postoperative
Quality of Recovery After Laparoscopic Cholecystectomy Comparing Opioid Free Analgesia Versus Opioid Free Anesthesia
The aim of this study is to compare the quality of recovery from general anesthesia and surgery using the quality of recovery 15 item scale (QoR-15) for participant's receiving opioid-Sparing anesthesia with those receiving…
- Conditions
- Quality of Recovery, Pain, Postoperative, Elective Laparoscopic Cholecystectomy
- Trial name
- NCT06343753
- Testing
- Opioid free analgesia, Opioid based Anesthesia
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Sudden Cardiac Arrest
Sodium Bicarbonate in Cardiopulmonary Resuscitation
Out-of-hospital cardiac arrests (OHCA) account for over 60% of deaths from coronary artery disease. The annual incidence of OHCA treated by Emergency Medical Systems (EMS) is 41-89 per 100,000 population.
- Trial name
- SB CAT (NCT01377337)
- Testing
- sodium bicarbonate
- Where
- 2 sites in Israel
- Volunteers
- 2,130 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Obesity, Neuraxial Ultrasound
Neuraxial Anaesthesia: Does BMI Relate to Ease of Neuraxial Anaesthesia?
Neuraxial anaesthesia can be more difficult and associated with more complications if the patient's bony landmarks are difficult to palpate.
- Conditions
- Obesity, Neuraxial Ultrasound, Obstetric Anaesthesia
- Trial name
- NCT03315845
- Testing
- Palpation of bony landmarks for neuraxial anaesthesia.
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Maternity Hospital, Ireland
Endotoxemia
Effect of Selective iNOS Inhibition During Human Endotoxemia
Sepsis or endotoxemia is manifested by hypotension, resistance to vasopressors, myocardial depression,and altered organ blood flow distribution.
- Trial name
- NCT00184990
- Testing
- Aminoguanidine, endotoxin
- Where
- Netherlands
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Anxiety, Carpal Tunnel Syndrome
Effect of High-quality Pre-operative Videos on Patient Anxiety Levels Prior to Ambulatory Hand Surgery
Previous research has shown that YouTube is a poor source of high-quality medical information. This is likely because there is no regulation of the content on YouTube and relatively little of the content is posted by qualified…
- Conditions
- Anxiety, Carpal Tunnel Syndrome, Trigger Finger, Engagement, Patient
- Trial name
- NCT04424810
- Testing
- High-quality, physician created video, Standard of care
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- Northwell Health
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