Clinical trials: Symptomatic Gallstones
Cholecystolithiasis
UDCA for Symptomatic Gallstone Disease
We conduct a randomized, double-blind, placebo-controlled trial on effects of UDCA on biliary pain and complications in highly symptomatic gallstone patients scheduled for cholecystectomy.
- Trial name
- NCT00161083
- Testing
- ursodeoxycholic acid
- Where
- Netherlands
- Volunteers
- 180 people
- Sponsor
- UMC Utrecht
Gallstones, Gallstone Attack
The Pro-Chol Study
This prospective clinical cohort study will include patients with gallstones and abdominal pain scheduled for surgery (laparoscopic cholecystectomy).
- Conditions
- Gallstones, Gallstone Attack, Uncomplicated Cholelithiasis, Cholecystolithiasis
- Trial name
- ProChol (NCT07245108)
- Testing
- Laparoscopic cholecystectomy
- Where
- 7 sites in Denmark
- Volunteers
- 800 people
- Sponsor
- Nordsjaellands Hospital
Cholecystolithiasis, Cholecystitis
Laparoscopic Transvaginal Hybrid Cholecystectomy: a Prospective Data Collection.
Transvaginal hybrid procedures especially the transvaginal hybrid cholecystectomy are of interest as an available NOTES-Procedure for the clinical routine.
- Trial name
- NCT00940264
- Testing
- transvaginal hybrid cholecystectomy
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Ignazio Tarantino
Gallstone
The Risk Factors of Symptomatic Gallbladder Stone: Age-Sex Matched Case-control Study Performed in Single Institute
The main purpose of this study is to investigate the region-specific cause of gallbladder stone incidence in Jeju Self-Governing Province, Korea.
- Trial name
- NCT02808546
- Volunteers
- 342 people
- Sponsor
- Cheju Halla General Hospital
Gallstone Disease
Multimedia Informed Consent & PROMs in Laparoscopic Cholecystectomy
Collection of PROMs (Patient Reported Outcome Measures) data from patients before and after an operation to remove their gallbladder for the treatment of symptomatic gallstones.
- Trial name
- EPICS (NCT02810860)
- Testing
- Laparoscopic cholecystectomy
- Where
- United Kingdom
- Volunteers
- 349 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Cholelithiasis
Does ICG Fluorescence Cholangiography Identify Critical View of Safety Earlier in Laparoscopic Cholecystectomy
Achievement of critical view of safety (CVS) is recommended to reduce risk of hilar injury in laparoscopic cholecystectomy. Indocyanine green (ICG) fluorescence cholangiography, a novel technique of real time biliary…
- Trial name
- NCT04228835
- Testing
- Fluorescence Cholangiography
- Where
- Malaysia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Malaya
Cholelithiasis
Lithotripsy for the Treatment of Gallstones
The purpose of this study is to determine the effectiveness and safety of using the Medstone lithotripter to treat single non-calcified gallstones from 4 to 20 mm in diameter.
- Trial name
- NCT00042549
- Testing
- Extracorporeal Shock Wave Lithotripsy, ursodiol
- Where
- 2 sites in United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Medstone International
Symptomatic Gallstones, Gallbladder Polyp
AI-Assisted Cholecystectomy Study
The objective of this prospective clinical pilot study is to evaluate the clinical feasibility, safety, and workflow integration of the voice-based AI-assisted robotic system for performing selected auxiliary tasks during robotic…
- Trial name
- NCT07705828
- Testing
- AI-Assisted Cornerstone Robotics Sentire Surgical System
- Where
- Hong Kong
- Volunteers
- 10 people
- Sponsor
- Chinese University of Hong Kong
Cholecystolithiasis
The Effect of High Frequency Jet Ventilation (HFJV)During Laparoscopic Operations
Investigators conducted a randomised perspective study to determine whether the use of HFJV instead of conventional mechanical ventilation will reduce the adverse cardiovascular effects of pneumoperitoneum during laparoscopic…
- Trial name
- HFJV (NCT01289379)
- Testing
- High Frequency Jet Ventilation, HFJV
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Gallstone Disease
Technical Feasibility of Routine Intraoperative Cholangiography During Elective Rigid-hybrid Transvaginal Natural Orifice Transluminal Endoscopic Cholecystectomy
While gold standard in the treatment of symptomatic gall stones is laparoscopic cholecystectomy with instruments introduced through multiple abdominal wall incisions, transvaginal access to the peritoneal cavity offers an…
- Trial name
- NCT01583348
- Testing
- Cholangiography during transvaginal rigid-hybdrid NOTES cholecystectomy
- Where
- Switzerland
- Volunteers
- 33 people
- Sponsor
- Cantonal Hospital, Baselland
Laparoscopic Cholecystectomy
Single Incision Versus Three Port Laparoscopic Cholecystectomy
Laparoscopic cholecystectomy (LC) became the standard treatment for symptomatic gallbladder disease. Single incision laparoscopic surgery (SILS) was developed with the aim of reducing the invasiveness of conventional laparoscopy.
- Trial name
- NCT03067038
- Testing
- Single incision laparoscopic cholecystectomy, Three port laparoscopic cholecystectomy
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- South Valley University
Gallstones
EndoCone Single Port Versus Conventional Multi-port Laparoscopic Approach
Its main objective is to evaluate the clinical outcome (including patient reported outcomes) and health economic assessment (HTA) of a new re-usable system for Single Port Laparoscopic Surgery - ENDOCONE SYSTEM developed by Prof…
- Trial name
- NCT01709877
- Testing
- Cholecystectomy
- Where
- 4 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Azienda Ospedaliero, Universitaria Pisana
Bile Duct; Obstruction, With Calculus, Choledocholithiasis
Clinical Trial Comparing ERCP vs ERCP and Transmural Gall Bladder Drainage
Cholelithiasis occurs in 10-20% of the general population. Up to 18% of these subjects will present symptoms. In patients with symptomatic choledocholithiasis who are not candidates for surgery with indication for ERCP…
- Trial name
- PECAS (NCT03921502)
- Testing
- Gall bladder transmural drainage with LAMS
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital del Rio Hortega
Cholelithiasis, Symptomatic Gallstone Disease
Hasson Versus Veress Access With Umbilical Versus Epigastric Gallbladder Extraction in Laparoscopic Cholecystectomy
This single-centre randomised pilot study compared two strategies for primary abdominal access and gallbladder extraction in elective laparoscopic cholecystectomy: open (Hasson) umbilical access with extraction of the gallbladder…
- Trial name
- NCT07887139
- Testing
- Hasson open access and umbilical gallbladder extraction, Veress needle access and epigastric gallbladder extraction
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people
- Sponsor
- Sedat Tan
Gallstones
A Clinical Trial of Electro-acupuncture for Treating Gallstone Diseases
Background: Electro-acupuncture (EA) is commonly used as an alternative treatment for gallstone disease. This study aimed to investigate the effectiveness of EA.
- Trial name
- NCT03891147
- Testing
- Electro-acupuncture
- Where
- China
- Volunteers
- 132 people
- Sponsor
- Chinese University of Hong Kong
Symptomatic Gallbladder Stones, Cholecystitis
Single Port Access (SPA) Cholecystectomy Versus Standard Laparoscopic Cholecystectomy
Background: Single port access surgery is a rapidly progressing surgical approach which allows performance of standard laparoscopic surgery through a single transparietal port instead of multiple port accesses.
- Conditions
- Symptomatic Gallbladder Stones, Cholecystitis, Biliary Pancreatitis
- Trial name
- NCT00904865
- Testing
- SPA cholecystectomy, Laparoscopic cholecystectomy
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- University Hospital, Geneva
Symptomatic Gallstone Disease
Cosmesis and Body Image After Single Port or 4-Port Laparoscopic Cholecystectomy
Laparoscopic Cholecystectomy (LC) is the treatment of choice for symptomatic gallstone disease. Single-port access cholecystectomy (SL) has been recently introduced using only one, trans-umbilical placed port.
- Trial name
- NCT01278472
- Testing
- Single Port Cholecystectomy, 4 Port Cholecystectomy
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- University of Zurich
Biliary Dyskinesia, Gallstones
Single-Incision Laparoscopic Cholecystectomy Versus Traditional Laparoscopic Cholecystectomy
This study will compare Single Incision Laparoscopic Surgery (SILS) cholecystectomy to traditional laparoscopic cholecystectomy (LC), focusing on patient-reported outcomes and cost.
- Conditions
- Biliary Dyskinesia, Gallstones, Cholecystitis, Cholelithiasis
- Trial name
- NCT01195285
- Testing
- Single-Incision Laparoscopic Surgery cholecystectomy, Traditional Laparoscopic Cholecystectomy (TLC)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Saint Luke's Health System
Bariatric Surgery Candidate, Cholelithiases
Multicenter Cohort of 768 High-risk Patients With Symptomatic Gallstones, Adding Cholecystectomy Did Not Increase Length of Stay or Perioperative Morbidity, Supporting it as a Safe Single-stage Option
Despite numerous single-center reports and meta-analyses, few studies have directly compared outcomes of LSG with versus without concomitant cholecystectomy exclusively in a high-risk cohort as defined above.
- Trial name
- NCT07772440
- Volunteers
- 2,512 people
- Sponsor
- Zagazig University