Clinical trials: Symptomatic Colorectal Cancer
Bowel Obstruction, Bowel Ischemia
Perfusion Rate Assessment by Near-infrared Fluorescence in Gastrointestinal Anastomoses
In this prospective, non-randomized cohort study, real-time intraoperative visualization using near-infrared-fluorescence by indocyanine green injection (ICG-NIRF) is performed at two to three time points during procedures of…
- Conditions
- Bowel Obstruction, Bowel Ischemia, Diverticulitis, Abnormality of the Gastrointestinal Tract
- Trial name
- NCT04709445
- Testing
- ICG-NIRF Imaging plus ingress and egress analysis
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Colorectal Cancer
Point of Care Faecal Immunochemical Testing for Colorectal Cancer
Blood that can be detected in stool via faecal immunochemical testing is a recognised risk factor for the presence of colorectal cancer. There are a number of point of care faecal immunochemical testing devices available.
- Trial name
- POCFIT (NCT04402424)
- Testing
- Faecal Immunochemical Testing
- Where
- United Kingdom
- Volunteers
- 631 people
- Sponsor
- Royal Surrey County Hospital NHS Foundation Trust
Colorectal Cancer
4-week Serial FIT Analysis in Patients With CRC
Assimilation of FIT into primary and secondary care diagnostic pathways will lead to an increased prominence of the investigation in the diagnosis of colorectal cancer (CRC).
- Trial name
- NCT04242901
- Testing
- Faecal Immunochemical Test - OC Sensor, Eiken, Tokyo
- Where
- United Kingdom
- Volunteers
- 58 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Symptomatic Colorectal Cancer, Advanced Colorectal Cancer
A Phase 3 Study to Evaluate Xilonix as an Anticancer Therapy in Patients With Symptomatic Colorectal Cancer
The primary objective of this study will be to assess how effective Xilonix is in the treatment of patients with symptomatic colorectal cancer.
- Conditions
- Symptomatic Colorectal Cancer, Advanced Colorectal Cancer, Colorectal Cancer With Cachexia
- Trial name
- NCT02138422
- Testing
- Xilonix
- Where
- Poland
- Volunteers
- 276 people
- Sponsor
- Janssen Research & Development, LLC
Colorectal Cancer
Accuracy and Predictive Values for Colorectal Cancer of Quantitative FIT in Symptomatic Patients in Primary Care
The aim of this study is to determine accuracy and predictive values for colorectal cancer of a faecal quantitative immunochemical test (FIT) in unselected symptomatic patients presenting in primary care.
- Trial name
- NCT05156307
- Where
- Sweden
- Volunteers
- 2,500 people
- Sponsor
- Region Örebro County
Colorectal Cancer, Adenoma Colon Polyp
Triple Assay of Rectal Mucus in the Diagnosis of Colorectal Cancer
Development of a multiomics assay for use on OriColTM sampled rectal mucus for detection of cancer and significant polyps in symptomatic patients on the Colorectal Urgent Suspected Cancer pathway.
- Trial name
- TRIOMIC (NCT06649123)
- Testing
- Oricol Test
- Where
- United Kingdom
- Volunteers
- 6,600 people
- Sponsor
- Origin Sciences
Colorectal Neoplasia, Intestinal Neoplasms
Endorings™ Assisted Colonoscopy Versus Standard Colonoscopy for Polyp Detection
This study evaluates the impact of Endorings™ assisted colonoscopy on the number of polyps detected per patient compared to standard colonoscopy without use of EndoRings™.
- Conditions
- Colorectal Neoplasia, Intestinal Neoplasms, Digestive Neoplasms, Digestive System Disease
- Trial name
- Erings™ (NCT02785783)
- Testing
- Standard colonoscopy, EndoRings™
- Where
- United Kingdom
- Volunteers
- 563 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Cancer Colon, Cancer, Liver
Clinical Validation of an MCED Test in Symptomatic Populations (K-ACCELERATE)
To evaluate the diagnostic performance of blood-based SPOT-MAS test in symptomatic individuals, the investigators sought to launch a prospective multicenter study, named K-ACCELERATE.
- Conditions
- Cancer Colon, Cancer, Liver, Cancer, Lung, Cancer, Breast
- Trial name
- K-ACCELERATE (NCT06391749)
- Where
- Vietnam
- Volunteers
- 1,000 people
- Sponsor
- Gene Solutions
Colorectal Neoplasms, Intestinal Neoplasms
Palliative Primary Tumor Resection in Minimally Symptomatic Patients With Colorectal Cancer and Synchronous Unresectable Metastases
Currently, the question remains whether palliative primary tumor resection could improve overall survival of minimally symptomatic patients with colorectal cancer and synchronous unresectable metastases.
- Conditions
- Colorectal Neoplasms, Intestinal Neoplasms, Gastrointestinal Neoplasms, Digestive System Neoplasms
- Trial name
- NCT05322486
- Testing
- surgery of the primary tumour, chemotherapy
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Colorectal Cancer, Age Problem
A Cross-sectional Survey of Colorectal Cancer Patients in Different Age Groups
This study will help to determine the main clinical symptom differences between patients of different ages, discover the family genetic predisposition of patients of different ages, and obtain the differences in pathological…
- Trial name
- NCT06145230
- Where
- China
- Volunteers
- 430 people
- Sponsor
- Wang Guiyu
Symptomatic Venous Thromboembolism, Asymptomatic Venous Thromboembolism
Incidence of Venous Thromboembolism Following Surgery in Patients With Colorectal Cancer
Venous thromboembolism (VTE) has harmful effects on morbidity and mortality of cancer patients. In Western VTE guidelines, all solid cancer patients receiving abdominal major surgery are strongly recommended to receive…
- Trial name
- NCT01567917
- Testing
- CRC surgery
- Where
- South Korea
- Volunteers
- 600 people
- Sponsor
- Seoul National University Bundang Hospital
Anemia, Breast Cancer
Assessment of Quality of Life in Patients With Symptomatic Chemotherapy-induced Anaemia
This is a multicenter, international, prospective, observational study of patients who are receiving systemic chemotherapy for solid tumour cancers (breast, colorectal, ovarian, prostate, lung, bladder, endometrial, renal…
- Conditions
- Anemia, Breast Cancer, Cancer, Colorectal Cancer
- Trial name
- NCT01444456
- Where
- 117 sites in Austria, Belgium and 7 more
- Volunteers
- 1,262 people
- Sponsor
- Amgen
Rectal Cancer
Rectal Cancer Trial On Defunctioning Stoma
The hypothesis of the present trial was that the use of a defunctioning loop stoma reduces the rate of symptomatic anastomotic leakage from 15% to 7.5% after low anterior resection of the rectum for cancer.
- Trial name
- RECTODES (NCT00636948)
- Where
- Sweden
- Volunteers
- 234 people
- Sponsor
- Rectal Cancer Trial on Defunctioning Stoma Study Group
Colorectal Adenoma
Comparisons of Endo-Wing-assisted Colonoscopy Versus Standard Colonoscopy in Improving Adenoma Detection Rate in Symptomatic Patients Suspected of Colorectal Cancer
Colorectal cancer (CRC) is the most common cancer in Malaysia. Colonoscopy is the gold standard for bowel cancer screening and the diagnosis of bowel pathology.
- Trial name
- NCT06859125
- Testing
- Endo-Wing™ (Shangxian Minimal Invasive Inc, China), Standard Colonoscopy
- Where
- Malaysia
- Volunteers
- 192 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Colorectal Neoplasms
Quantitative Immunochemical Fecal Occult Blood Test in Symptomatic Patients
The aim of this study is to compare the outcome of three (3) quantitative immunochemical faecal occult blood test in symptomatic patients.
- Trial name
- FIKA (NCT02491593)
- Testing
- fecal occult blood test
- Where
- Sweden
- Volunteers
- 242 people
- Sponsor
- Uppsala University