Clinical trials: Swallowing Disorders
Ischemic Stroke, Post-stroke Dysphagia
EEG Feedback-Based Vagus Nerve Stimulation for Post-Stroke Dysphagia
The goal of this clinical trial is to learn if electroencephalogram (EEG) biofeedback-guided transcutaneous auricular vagus nerve stimulation (taVNS) works to treat swallowing difficulties (dysphagia) in adults after a stroke.
- Conditions
- Ischemic Stroke, Post-stroke Dysphagia, Swallowing Disorders
- Trial name
- NCT07894315
- Testing
- EEG Biofeedback-Guided taVNS, Conventional taVNS
- Where
- 6 sites in China
- Volunteers
- 60 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Swallowing Difficulties, Thirst
Effect of Cold Water Spray on Swallowing Difficulty, Pain, and Thirst After Thyroid Surgery
Dysphagia and thirst are common in the early period after thyroidectomy and negatively affect patient comfort. This study aims to evaluate the effect of cold water spray on dysphagia, pain during swallowing, and thirst after…
- Conditions
- Swallowing Difficulties, Thirst, Thyroidectomy
- Trial name
- CWS-THY (NCT07879404)
- Testing
- Cold water spray
- Where
- Turkey (Türkiye)
- Volunteers
- 108 people
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Swallowing Disorders
Radiation-Related Dysphagia Development Prediction Using a Two-Step Ultrasonographic Model (R-2D-2)
Radiotherapy for head and neck cancers (H\&NC) heightens the risk of swallowing disorders (SD), impacting nutrition, quality of life, and overall health, leading to increased hospitalization and mortality.
- Trial name
- R-2D-2 (NCT06387004)
- Where
- France
- Volunteers
- 112 people
- Sponsor
- Hopital Forcilles
Swallowing
Longitudinal Ultrasound Kinematic Evaluation of Digastric Muscles
Ultrasound applied to the upper aerodigestive tract for the assessment of swallowing disorders has been the subject of numerous publications in recent years.
- Trial name
- LUKE (NCT07670429)
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hopital Forcilles
Stroke, Dysphagia
Effect of Kinesio Taping Applied to the Suprahyoid Muscles on Swallowing Safety in Patients With Post-Stroke Dysphagia
Dysphagia is defined as a disorder that occurs during the process of food transfer, beginning with oral intake and continuing until it reaches the stomach.
- Conditions
- Stroke, Dysphagia, Swallowing Disorder
- Trial name
- Post-Stroke KT (NCT07255352)
- Testing
- Kinesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people
- Sponsor
- Harran University
Head and Neck Neoplasms, Swallowing Sparing IMRT
The SWOAR Trial Sparing of Swallowing and Aspiration Related Organs at Risk & Submandibular Gland With Intensity Modulated Radiotherapy Versus Standard IMRT in Head and Neck Squamous Cell Carcinomas
The aim of SWOAR TRIAL is to test sparing of Dysphagia/ Aspiration risk structures (DARS) and contra lateral submandibular gland by IMRT.
- Trial name
- SWOAR (NCT05187091)
- Testing
- Swallowing and submandibular sparing IMRT, Standard IMRT with medical CRT/RT, Cisplatine
- Where
- India
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences
Dysphagia, Swallowing Disorders
taVNS in Infants Severe Dysphagia
This study evaluates the safety, feasibility, and preliminary effects of transcutaneous auricular vagus nerve stimulation (taVNS) paired with an oral sensorimotor training protocol in infants with severe dysphagia.
- Conditions
- Dysphagia, Swallowing Disorders, Feeding and Eating Disorders of Infancy
- Trial name
- NCT07802301
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Oral Sensorimotor Training Protocol
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina
Stroke, Swallowing Disorders
Comparison of NMES, tDCS, and TMS Treatments in Post-Stroke Dysphagia
This randomized, single-blind, controlled clinical trial aims to compare the effectiveness of neuromuscular electrical stimulation (NMES) administered alone or in combination with transcranial direct current stimulation (tDCS) or…
- Conditions
- Stroke, Swallowing Disorders, Dysphagia
- Trial name
- NCT07793799
- Testing
- Neuromuscular Electrical Stimulation, Active Transcranial Direct Current Stimulation, Active Transcranial Magnetic Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Atlas University
Swallowing Disorder.Other Specified
Electromagnetic Therapy for Cervicogenic Dysphagia
Cervicogenic dysphagia (CD) is a swallowing disorder in patients with cervicogenic pathology. Pulsed electromagnetic therapy (PEMT) is a widely utilized therapeutic modality.
- Trial name
- NCT07765043
- Testing
- The pulsed electromagnetic field treatment program plus the swallowing resistance training program
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- Umm Al-Qura University
Swallowing Disorders
Modelling of Pharyngeal Laryngeal Effectiveness
The purpose of this study is to collect the signals of pharyngeal laryngeal activity through five non-invasive sensors (microphone, accelerometer, surface electromyography (EMG), nasal cannula and oximeter) in order to identify…
- Trial name
- Eph-L (NCT06014710)
- Testing
- Swallowing evaluation
- Where
- 4 sites in France
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- University Hospital, Toulouse
Nutrition Disorders, Gastrointestinal Disease
Review of Infant Oral Feeding and Skills
This study evaluates the infant's feeding skill level at discharge from the neonatal intensive care unit. The goal is to determine whether the ability to "full feed by volume" implies "full skill development" for infant oral…
- Conditions
- Nutrition Disorders, Gastrointestinal Disease, Deglutition Disorder, Feeding Difficulties
- Trial name
- RIOS (NCT06736743)
- Testing
- SMART Tool for Feeding Skill Assessment
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Wake Forest University Health Sciences
Swallowing Disorders, Aspiration
Ultrasound vs. Nasofibroscopy for Evaluating Dysphagia After Extubation in the ICU
The goal of this observational study is to evaluate the diagnostic performance and concordance of bedside cervical ultrasonography compared to Fiberoptic Endoscopic Evaluation of Swallowing (FEES) for the early detection of…
- Trial name
- DISFEX (NCT07734298)
- Testing
- Bedside Cervical Ultrasonography, Fiberoptic Endoscopic Evaluation of Swallowing (FEES)
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Hospital H+ Queretaro
Swallowing Function, Swallowing Risk
DDK Acoustic Analysis and Swallowing Indicators
This study examines whether simple speech tasks and a swallowing screening test can help identify swallowing risk in adults of different ages.
- Conditions
- Swallowing Function, Swallowing Risk, Dysphagia
- Trial name
- AAP-DDK (NCT07626749)
- Where
- Taiwan
- Volunteers
- 720 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University
Oropharyngeal Dysphagia (OPD), Parkinson
Results of Combined Medical and Swallowing Behavioral Readjustment Therapy in Oropharyngeal Dysphagia Management Among Parkinson's Patients
The study aims to assess the efficacy of using swallowing behavioral readjustment technique in combination with medical treatment in management of oropharyngeal dysphagia among Parkinson's patients in order to improve the…
- Conditions
- Oropharyngeal Dysphagia (OPD), Parkinson, Swallowing Difficulties
- Trial name
- NCT07618637
- Testing
- combined pharmaceutical treatment and rehabilitation techniques, pharmaceutical treatment only
- Where
- Egypt
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Tanta University
Dysphagia, Swallowing Disorders
Novel Pharyngeal Metrics to Predict Dysphagia Outcomes
This multi-site trial will follow a cohort of Veterans with dysphagia for 8 weeks as they undergo clinically guided oropharyngeal exercises with oropharyngeal strengthening as the primary goal.
- Trial name
- NCT04569097
- Testing
- standard of care lingual strengthening
- Where
- 3 sites in United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Anastomotic Leak Esophagus, Swallowing Disorder
Functional Outcome After Anastomotic Leak After Oesophagectomies
The main surgical treatment for oesophageal cancer is a curative resection, mostly performed according to Ivor Lewis. However, despite careful work and refined surgical techniques, anastomotic leakage (AL) occurs in more than…
- Trial name
- FOAL (NCT05945654)
- Testing
- Anastomotic Leak after Ivor Lewis Oesophagectomy
- Where
- Switzerland
- Sponsor
- Stefan Gutknecht
Dysphagia After Stroke, Stroke
Effect of Visual Biofeedback-Assisted Oropharyngeal Exercises in Post-Stroke Dysphagia
Post-stroke dysphagia is a common complication that negatively affects nutritional status, quality of life, and morbidity. Conventional swallowing rehabilitation, including oropharyngeal exercises and neuromuscular electrical…
- Conditions
- Dysphagia After Stroke, Stroke, Dysphagia, Swallowing Disorders
- Trial name
- NCT07492719
- Testing
- Suprahyoid Neuromuscular Electrical Stimulation (NMES), Visual Biofeedback Training, Conventional Oropharyngeal Exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Gazi University
Velopharyngeal Insufficiency, Swallowing
Velopharyngeal Insufficiency After Maxillomandibular Advancement Osteotomy in Obstructive Sleep Apnea Patients
The aim of this study is to gain insight into the development of velopharyngeal insufficiency (VPI) in patients who have undergone maxillomandibular advancement osteotomy (MMA) as a treatment for obstructive sleep apnea syndrome…
- Conditions
- Velopharyngeal Insufficiency, Swallowing, Nasality, Speech
- Trial name
- VPIMMA (NCT07301021)
- Where
- Netherlands
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Swallowing Disorder, Dysphagia
Cross Cultural Validation of the Italian Version of the Clinical Assessment of Dysphagia in Neurodegeneration
The English version of the "Clinical Assessment of Dysphagia in Neurodegeneration" (CADN), represents a rapid and valid clinical assessment tool for dysphagia in neurodegenerative population.
- Conditions
- Swallowing Disorder, Dysphagia, Neuro-Degenerative Disease
- Trial name
- NCT05733494
- Testing
- Administration of Clinical Assessment of Dysphagia in Neurodegeneration (CADN)
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Difficulty Swallowing
THE IMPACT OF NURSİNG CARE ON COMPLİCATİON İN PEG PATİENTS
This study was conducted to investigate the impact of nursing care on complications in patients undergoing percutaneous endoscopic gastrostomy (PEG) placement.
- Trial name
- NCP-PEG (NCT07436442)
- Testing
- customized training
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey