Clinical trials: Survival
Postoperative Pain, Postsurgical Pain
Influence of Insertion Torque and Bone Type on Post-operative Pain
The objectives of this clinical study were to assess the effect of different ITs and bone types on POP levels and survival rates and to investigate the effect of different patient- and site-related factors on POP levels and…
- Conditions
- Postoperative Pain, Postsurgical Pain, Dental Implant Failed
- Trial name
- NCT06412380
- Testing
- Implant insertion
- Where
- United Arab Emirates
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Sharjah
Esophageal Squamous Cell Carcinoma
Multi-institutional Analysis of Survival and Recurrence Patterns of Different Pathological Regression Types After Neoadjuvant Chemoradiotherapy or Radiotherapy for Esophageal Squamous Cell Carcinoma
The goal of this multicenter retrospective cohort study is to evaluate the impact of different pathological regression types on survival and recurrence patterns, with a particular focus on ypT0N+ patients in patients with…
- Trial name
- NCT06241079
- Testing
- non-intervention
- Volunteers
- 582 people
- Sponsor
- Tianjin Medical University Cancer Institute and Hospital
Lung Cancer (NSCLC), Neoadjuvant Immunotherapy
Safety, Efficacy, and Survival Outcomes of Neoadjuvant/Induction Immunotherapy in Surgical and Radiotherapeutic Management of Non-Small Cell Lung Cancer
This multicenter retrospective real-world study aims to evaluate the safety, efficacy and survival outcomes of neoadjuvant/induction immunotherapy in patients with non-small cell lung cancer (NSCLC).
- Conditions
- Lung Cancer (NSCLC), Neoadjuvant Immunotherapy, Radiotherapy, Lung Surgery
- Trial name
- NCT06926179
- Testing
- neoadjuvant immunotherapy
- Where
- 4 sites in China
- Volunteers
- 500 people
- Sponsor
- Peking University Cancer Hospital & Institute
Progression-free Survival Was Defined From Date of Surgery to Disease Progression Post-surgery or Death or Last Follow-up, Overall Survival Was Defined as Time From Surgery to Death From Any Cause or Last Follow-up
Observational, Bivariate Analysis of Clinical Big Data in Patients With Cervical Cancer
This is a large non-interventional observational bidirectional study planned to collect clinically relevant data and prognostic follow-up information of patients with cervical cancer who were seen at our center from 2010.01.01 to…
- Trial name
- NCT06480617
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Anhui Provincial Hospital
Renal Transplantation
Calcineurin Inhibitor (CNI) Versus Steroid Cessation in Renal Transplantation
This study intends to determine whether steroid withdrawal or calcineurin inhibitor withdrawal is superior for graft function and graft survival.
- Trial name
- CISTCERT (NCT00903188)
- Testing
- cyclosporine, Everolimus
- Where
- 5 sites in Belgium
- Volunteers
- 152 people
- Sponsor
- University Hospital, Antwerp
Irreversible Intestinal Failure, Allograft Rejection
Low Dose Irradiation for Small Bowel Transplant
The specific aims of this study is to improve short and long-term patient and graft survival, to reduce the incidence and severity of allograft rejection, to reduce the incidence of infection and to reduce and/or eventually…
- Trial name
- NCT00382486
- Testing
- Reduce the risk of allograft rejection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Cancer Head Neck
Single and Combined Modality Trans-Oral Robotic Surgery in Early Oropharyngeal Cancer
Multi-centre retrospective observational cohort study with optional exploratory radiomic study (international) and prospective molecular analysis studies (UK only).
- Trial name
- SCORE (NCT05933889)
- Testing
- Molecular Analysis, Radiomic/ Morphological analysis
- Where
- United Kingdom
- Volunteers
- 250 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Cardiac Transplant Disorder
Don't Throw Your Heart Away: Medical Student Study 2
Publicly available outcome assessments for transplant programs do not make salient that some programs tend to reject many of the hearts they are offered, whereas other programs accept a broader range of donor offers.
- Trial name
- NCT04176796
- Testing
- Stratified Transplant Survival
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Carnegie Mellon University
Major Surgery
Long-term Enlarged Survival After an Enhanced Recovery Protocol (LESAS).
The main objective of this study is to analyze the impact on three years survival of an enhanced recovery program (PRI) after radical surgery for colorectal cancer.
- Trial name
- LESAS (NCT04305314)
- Testing
- PRI (Enhanced Recovery after surgery protocol)
- Where
- 12 sites in Spain
- Volunteers
- 750 people
- Sponsor
- Grupo Español de Rehabilitación Multimodal
Lung Cancer
Avoiding Cardiac Toxicity in Lung Cancer Patients Treated With Curative-intent Radiotherapy
Radiotherapy plays a major role in the treatment of lung cancer and recent advances in radiotherapy have led to better cure rates.
- Trial name
- ACCOLADE (NCT03645317)
- Testing
- Blood tests & cardiac imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Prof Corinne Faivre-Finn
Stage I-II Pancreatic Ductal Adenocarcinoma (PDAC), Precise Prognostic and Predictive Signature
Precise Gene Signature for Predicting Outcomes in PDAC
The current TNM staging system is not sufficient for prediction of prognosis and cannot precisely identify the patients who are in greater need of adjuvant therapy in pancreatic ductal adenocarcinoma (PDAC).
- Trial name
- NCT05441189
- Testing
- Resection
- Where
- China
- Volunteers
- 70 people
- Sponsor
- The Fourth Affiliated Hospital of Anhui Medical University
Breast Cancer Female, Survivorship
Nurse-led Physical Activity Program Among Breast Cancer Survivors
A nurse-led physical activity program including an individualized exercise program using wearable technology and health coaching based on Social Cognitive Theory will be implemented for women surviving cancer.
- Conditions
- Breast Cancer Female, Survivorship, Health Behavior
- Trial name
- WATSOCPAP (NCT06248918)
- Testing
- WATSOCPAP
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Cholangiocarcinoma
the Impact of Early Palliative Care on the Survival of Locally Advanced and / or Metastatic Cholangiocarcinoma Patients
The prognosis for cholangiocarcinoma is bad. Potentially, early management by a palliative care team could increase overall survival.
- Trial name
- NCT04415190
- Testing
- early palliative care
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Oncology, Survivorship
A Symptom Management Application for Children at the Early Stage of Cancer Survivorship and Their Caregivers
The goal of this randomized controlled trial is to examine the efficacy of the mHealth app in improving symptoms experienced by children in the early stage of cancer survivorship, including physical function, anxiety, depressive…
- Trial name
- NCT05748210
- Testing
- Symptom management mobile health application with personalised support, Wait-list Symptom management mobile health application with personalised support
- Where
- 2 sites in Hong Kong
- Volunteers
- 150 people
- Sponsor
- Chinese University of Hong Kong
Hematological Diseases
AlloCare - Support and Management of Late Effects After Allogeneic Hematopoietic Stem Cell Transplantation
A developed multimodal intervention targeting late effects in survivors of allogeneic hematopoietic stem cell transplantation (allo-HSCT) will be evaluated in a two-arm randomized controlled trial with an internal pilot phase.
- Trial name
- AlloCare (NCT06281496)
- Testing
- AlloCare
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Breast Cancer
A Mixed-Methods Metabolomics Investigation of Lifestyle and Energy Balance During Breast Cancer Survivorship
The MILES Study is a longitudinal, mixed-methods investigation of urinary biomarkers, energy balance, and lifestyle modifications in diverse women during early breast cancer treatment.
- Trial name
- MILES (NCT07655934)
- Testing
- Survey completion, Urine specimen banking, Qualitative interviews
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Head and Neck Cancer
Diet Intervention, Head and Neck Cancer, Feasibility
This study will examine the effects of a dietary intervention in post-treatment head and neck cancer survivors on the ability to function physically, tiredness, and quality of life, as well as on changing markers in the blood…
- Trial name
- NCT03013699
- Testing
- Cruciferous and Dark Leafy Green Intervention, Usual Dietary Care
- Volunteers
- 23 people
- Sponsor
- University of Alabama at Birmingham
Survival , Tumor
Colorectal Cancer Real-world Outcomes Study of Survival With Immunomodulator Plus Standard Anti-cancer Therapies
Colorectal cancer (CRC) is the third most common cancer worldwide. Despite the availability of numerous standard therapies for CRC, clinical outcomes from these treatments remain unsatisfactory.
- Trial name
- CROSS-02 (NCT07703709)
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chou-Chen Chen
Partial Edentulism, Disorder of Prostheses and Implants
Survival of Implant-Supported All-Ceramic Prostheses
The purpose of this research study is to identify reasons that cause an all-ceramic bridge to fracture which include the thickness of the bridge material, the type of bridge material and the bite force of the person.
- Conditions
- Partial Edentulism, Disorder of Prostheses and Implants, Dental Prosthesis Failure
- Trial name
- NCT01729858
- Testing
- Ceramic-Ceramic, Metal-Ceramic
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Florida
Critical Illness, Nurse's Role
Effect of Blood Group on the Survival Status of Intensive Care Patients
The research was planned to determine the effect of different blood groups on the 90-day survival of intensive care patients who were treated and maintained for the first time in the intensive care unit.
- Conditions
- Critical Illness, Nurse's Role, Risk Factor, Prognosis
- Trial name
- NCT04460625
- Where
- Turkey (Türkiye)
- Volunteers
- 3,114 people
- Sponsor
- Zonguldak Bulent Ecevit University