Clinical trials: Surgical Scar, active
Ultra Tension-Reducing Suture Technique
A Self-Controlled Clinical Study of Fast-Absorbable Versus Slow-Absorbable Sutures Applied in Ultra Tension-Reducing Suture Technique
Hypertrophic scar formation after wound healing remains a clinical challenge in plastic surgery. Ultra Tension-Reducing Suture Technique is currently the primary surgical option for preventing and reducing hypertrophic…
- Trial name
- NCT07639372
- Testing
- Intervention 1: 5-0 Slow-absorbable PDS suture, Intervention 2: 5-0 Fast-absorbable Vicryl suture
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhenzhen Zhang
Scar
Disposable Noninvasive Skin Closure for Promoting Postoperative Wound Healing and Preventing Surgical Skin Scarring
The purpose of this study is to evaluate the efficacy and safety of a disposable noninvasive skin closure device in promoting postoperative wound healing and reducing surgical scar formation.
- Trial name
- NCT07849010
- Testing
- Disposable Noninvasive Skin Closure Device (Shanghai Zhizhong Medical Technology Co., Ltd. Catalog No.: 240430PFF)
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Peking University Third Hospital
Skin Graft Scar
Surgical Outcomes of Simple Interrupted Versus Running Epidermal Sutures in Full-thickness Skin Graft Placement
The study hypothesis is that the use of running epidermal sutures in full-thickness skin graft (FTSG) placement for patients undergoing dermatologic surgery (Mohs micrographic surgery or excision) is non-inferior to the use of…
- Trial name
- NCT06233812
- Testing
- Simple interrupted suturing technique, Running suturing technique
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Post-surgical Scars, Hypertrophic Scars
Surgical Care And Recovery With Laser Evaluation Trial (SCARLET)
The Surgical Care and Recovery with Laser Evaluation Trial (S.C.A.R.L.E.T.) is a prospective, single-center clinical study conducted at AdventHealth Medical Group Plastic and Reconstructive Surgery at Innovation Tower.
- Conditions
- Post-surgical Scars, Hypertrophic Scars, Scar Appearance Dissatisfaction, Aesthetic Surgical Outcomes
- Trial name
- SCARLET (NCT07359352)
- Testing
- ProFractional Laser Therapy and/or Broadband Light (BBL) Treatment
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Surgical Wounds, Mohs Surgery
The Effects of Timolol On Healing and Cosmesis of Mohs Scalp Wounds: An Open Label Trial
The goal of this study clinical trial is to learn if topical timolol can accelerate healing and improve the cosmetic appearance of surgical wounds on the scalp following Mohs surgery.
- Trial name
- NCT07583862
- Testing
- Topical Timolol, Normal Saline
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Geisinger Clinic
Scarring
Outcomes of Running Locking Suture vs Standard Running Suture in Surgical Wounds
When patients have surgery on the head and face, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring.
- Trial name
- NCT06288009
- Testing
- Running locking suture, Standard running suture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Wound Healing
Plasma Therapy for Scar Management
This study is a prospective, multicenter, real-world observational study. It aims to evaluate whether adding plasma device therapy to standard scar care is effective and safe for treating various types of scars, including…
- Trial name
- NCT07548593
- Testing
- Plasma Device
- Volunteers
- 800 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Surgical Wound, Wound Heal
Influence of Sun Protection and Linear Repair of Cutaneous Surgical Defects
The purpose of this study is to determine the potential influence of sun protection on the aesthetic outcome of post-surgical scars following the reconstruction of Mohs micrographic surgery defects via linear repair.
- Conditions
- Surgical Wound, Wound Heal, Wound of Skin, Scar
- Trial name
- NCT05074238
- Testing
- Zinc containing suncreen
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Surgical Wound Healing, Botulinum Toxin, Type A
Botulinum Toxin Type A for Wound Healing After Laparoscopic Colectomy
This study aims to evaluate the efficacy and safety of botulinum toxin type A (BTX-A) injection as an adjunct to surgical wound healing in patients undergoing laparoscopic colectomy.
- Trial name
- NCT07795463
- Testing
- Botulinum toxin type A (Botox®, Allergan)
- Where
- Vietnam
- Volunteers
- 60 people
- Sponsor
- Pham Ngoc Thach University of Medicine
Scarring
Undermining Apices in Surgical Wounds
When patients have surgery on the neck, trunk, arms, or legs, stitches are the standard way to close the wound. Wounds always result in a scar, but doctors are always looking for ways to reduce scarring.
- Trial name
- NCT05758181
- Testing
- Apical Undermining
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Keloids, Keloids Scars
A Prospective Observational Clinical Study on Exploring the Value of Surgical Excision Combined With 32P Application in the Treatment of Keloids and the Factors Affecting the Prognosis of Combined Therapy
Keloids are non-cancerous (benign) growths on the skin. They form after an injury, when the skin makes too much connective tissue that thickens and hardens. These keloids cause big problems for people.
- Trial name
- NCT07413497
- Volunteers
- 401 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Wound Healing Disorder, Post-Surgical Complication
NovoX®Cup as Primary Dressing After Breast Reduction
Breast reduction is one of the most frequently performed plastic surgeries. Studies have shown that breast reduction surgery significantly improves the patients' suffering and leads to a better health-related quality of…
- Conditions
- Wound Healing Disorder, Post-Surgical Complication, Mammaplasty
- Trial name
- NCT06420323
- Testing
- Treatment with NovoX® Cup, Treatment with Omnistrip®
- Where
- Austria
- Volunteers
- 20 people
- Sponsor
- MOSS S.p.A.
Cesarean Scar Pregnancy
Comparison Between Surgical Excision and Ultrasound Guided Evacuation in Management of Cesarean Section Scar Pregnancy.
patients diagnosed with cesarean section scar ectopic pregnancy type II will be divided into two groups, one will undergo surgical excision and the other one will undergo ultrasound-guided evacuation in order to compare safety…
- Trial name
- NCT07166627
- Testing
- surgical excision of cesarean section scar ectopic pregnancy, ultrasound guided evacuation of cesarean section scar ectopic pregnancy
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Sohag University
Skin Wound Healing After Cesarean Section, Cesarean Section Scar Healing
Tissue-Engineered Construct Based on Amniotic Membrane and Calcium Alginate for Cesarean Section Wound Healing
This clinical trial aims to evaluate the safety and efficacy of an experimental tissue-engineered construct (TEC) based on amniotic membrane and calcium alginate for promoting epithelialization and improving scar quality in…
- Trial name
- NCT07241013
- Testing
- Tissue-engineered construct based on amniotic membrane and calcium alginate (TEC)
- Where
- Kazakhstan
- Volunteers
- 100 people
- Sponsor
- Asfendiyarov Kazakh National Medical University
Caesarean Scar Pregnancy
Surgical Evacuation Versus Methotrexate Injection in Treatment of Caesarean Scar Pregnancy [Clinical Trial ]
The aim of the study is to compare the effectiveness and the complications of Ultrasound guided surgical evacuation versus using combined local and systemic methotrexate injection for management of caesarean scar pregnancy.
- Trial name
- NCT07288307
- Testing
- Surgical evacuation and methotrexate injection
- Volunteers
- 42 people
- Sponsor
- Minia University
Cesarean Scar Pregnancy
Effect of Methotrexate on Blood Loss During Laparoscopic Management of CS Scar Pregnancy
Effect of Preoperative Methotrexate on Intraoperative Blood Loss and Surgical Outcomes During Laparoscopic Management of Cesarean Scar Pregnancy: A Prospective Cohort Study.
- Trial name
- CSEP (NCT07886216)
- Volunteers
- 42 people
- Sponsor
- Assiut University
Cleft Lip, Cleft Lip Scar
Cleft Lip Scarring After Botox
This study is investigating whether botulinum toxin type A (Botox) can improve scar appearance after cleft lip repair surgery. Cleft lip repair is commonly performed during infancy, but visible scarring can occur as the incision…
- Trial name
- CLSAB (NCT07880860)
- Testing
- Botulinum Toxin Type A (BOTOX) Injection, Normal Saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Children's National Research Institute
Surgical Scar, Postoperative Scar
Impact of Perioperative Antibiotic Use on Surgical Scarring
This retrospective observational cohort study will evaluate whether perioperative antibiotic use is associated with long-term surgical scar outcomes.
- Trial name
- PASS (NCT07741591)
- Testing
- Perioperative Antibiotic Exposure
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Lumbar Disc Disease
Postoperative Scar in the Control Excess of Mobility Induced by Annulus Removal on Inserting a Lumbar Disc Prosthesis
To implant a complete lumbar disc prosthesis removal of the anterior portion of the annulus fibrosus is required. As the anterior portion of the annulus limits the movement in extension and axial rotation, we would like to know…
- Trial name
- NCT04641039
- Testing
- Anterior lumbar disc annulus removal versus replacement
- Where
- Spain
- Volunteers
- 24 people
- Sponsor
- University of Valencia
Keloid of Ear Lobe
siRNA Microneedle Patches for Ear Keloid Post-Surgical Scars
The goal of this clinical trial is to evaluate whether small interfering RNA (siRNA) microneedle patches can improve the scar appearances of ear keloids treated with surgery.
- Trial name
- SILK (NCT07596628)
- Testing
- Small interfering RNA (siRNA) Microneedle Patches, Carbon Dioxide (CO2) Laser Surgery, Intralesional Triamcinolone 40 mg/mL
- Where
- Singapore
- Volunteers
- 158 people
- Sponsor
- Ong Kim Yao