Clinical trials: Surgical Injury
Patients With Spinal Stenosis Indicated for MIS TLIF
ESP Block in MIS Lumbar Spine Surgery
This is a prospective, randomized controlled trial of patients undergoing minimally invasive transforaminal lumbar interbody fusion.
- Trial name
- NCT05856539
- Testing
- Erector spinae plane (ESP) block
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Hospital for Special Surgery, New York
Rotator Cuff Injury
Rehabilitation After Rotator Cuff Repair
A new postoperative regimen with a new bandage technique after surgery results in a better shoulder function and quality of life after surgery - than traditional postoperative regimen with shoulder lock and abductor cushion.
- Trial name
- NCT02261701
- Testing
- Early mobilization, Post surgery shoulder lock
- Where
- Sweden
- Volunteers
- 76 people
- Sponsor
- Uppsala University
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Colon Cancer, Rectal Cancer
The Safety and Feasibility of MONOFIX on Fascial Closure of Mid-line Wound After Minimally Invasive Colorectal Cancer Surgery
This clinical trial aims to evaluate the safety and feasibility of mid-line fascial suturing using MONOFIX sutures in patients undergoing minimally invasive surgery for colorectal cancer.
- Conditions
- Colon Cancer, Rectal Cancer, Colon Adenocarcinoma, Rectal Adenocarcinoma
- Trial name
- NCT05872334
- Testing
- Monofix
- Where
- South Korea
- Volunteers
- 120 people
- Sponsor
- Samsung Medical Center
Hip Fractures
Hypobaric Lateral Spinal Anesthesia Versus General Anesthesia for the Hip Fracture Surgery
Hip fracture is a frequent pathology, involving elderly patients with many co-morbidities ; therefore, post-operative morbidity and mortality is high.
- Trial name
- RACHYP (NCT03373864)
- Testing
- Unilateral spinal anesthesia, General anesthesia
- Where
- France
- Volunteers
- 154 people
- Sponsor
- Hospices Civils de Lyon
Shoulder Dislocation, Glenohumeral Dislocation
Open Versus Arthroscopic Stabilization of Shoulder Instability With Subcritical Bone Loss: The OASIS Trial
This clinical trial will determine the outcome trajectories of common surgeries (arthroscopic Bankart repair with remplissage of a Hill-Sachs lesion, open Bankart, Latarjet) with post-operative rehabilitation and identification…
- Conditions
- Shoulder Dislocation, Glenohumeral Dislocation, Anterior Shoulder Dislocation
- Trial name
- OASIS (NCT04809064)
- Testing
- Arthroscopic Bankart repair procedure, Open Bankart, Latarjet
- Where
- 15 sites in United States
- Volunteers
- 450 people
- Sponsor
- University of Pittsburgh
Bleeding, Surgical Wound
Traumacel FAM Trium in the Post-market Surveillance Phase
The investigational medical device Traumacel FAM Trium is a sterile plant polysaccharide haemostatic agent based on the oxidized cellulose in the form of multilayer nonwoven fabric.
- Trial name
- NCT05177874
- Testing
- Traumacel FAM Trium, Surgicel Fibrillar
- Where
- Czechia
- Volunteers
- 98 people
- Sponsor
- Bioster, a.s.
Bone Metastases
Study of Denosumab vs. Zoledronic Acid to Treat Bone Metastases in Subjects With Advanced Cancer or Multiple Myeloma.
The purpose of this study is to determine if denosumab is non-inferior to zoledronic acid (Zometa®) in the treatment of bone metastases (lytic bone lesions from multiple myeloma) in subjects with advanced cancer and multiple…
- Trial name
- NCT00330759
- Testing
- Denosumab, Zoledronic Acid
- Volunteers
- 1,779 people
- Sponsor
- Amgen
Postoperative Wound Haemorrhage
Topical Tranexamic Acid Use on Granulating Wounds Following Mohs Micrographic Surgery
Bleeding after Mohs micrographic surgery for skin cancer is a low risk complication that can occur. This study aims to determine the effect of a drug, often used to reduce bleeding, called tranexamic acid when applied topically…
- Trial name
- NCT04541303
- Testing
- Tranexamic acid, normal saline
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Missouri-Columbia
Bicep Tendon Rupture
Evaluation of Clinical and Radiographic Findings in Patients Treated Surgically for Biceps Long Head Injury
This is an interventional, single-center study with clinical and radiographic evaluation, at follow-up of at least 2 years, of patients treated surgically with arthroscopy-assisted distal biceps tendon repair at the Rizzoli…
- Trial name
- Artro-Bic (NCT06483256)
- Testing
- radiographic control
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto Ortopedico Rizzoli
Gynecomastia, Surgical Incision
Modified Benelli Procedure For Subcutaneous Mastectomy
The study included 150 patients with gynecomastia (Grade II and III) for the period between January 2010 and January 2016 who attended private hospitals and Al- Kindy Teaching Hospital.
- Trial name
- NCT04063722
- Testing
- modified Benelli procedure
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Al-Kindy College of Medicine
Median Sternotomy
Study to Evaluate the Safety and Efficacy of Dermal Injections of JVS-100 Given to Adults Receiving Median Sternotomy
This study will investigate the safety and efficacy of using JVS-100 to accelerate wound healing and reduce scar formation in subjects receiving surgical incisions ("sternotomies") during cardiovascular surgery.
- Trial name
- NCT01657045
- Where
- 6 sites in United States
- Volunteers
- 25 people
- Sponsor
- SironRX Therapeutics, Inc.
Osteoporosis, Humerus Fracture
Influence of Osteoporosis on Clinical Outcomes of Mini-invasive Surgical Treatment of Proximal Humerus Fractures
Aim of the study is to analyze results of treatment of proximal humerus fractures with mini-invasive technique and plate fixation.
- Trial name
- NCT02750839
- Testing
- proximal humerus fracture fixation
- Volunteers
- 65 people
- Sponsor
- Azienda Ospedaliera Bolognini di Seriate Bergamo
Acute Kidney Injury
Arterial Stiffness and AKI Post-CABG
Acute Kidney Injury is a condition where your kidneys suddenly stop working properly and usually occurs if you are already unwell with an illness and can happen after having surgery.
- Trial name
- Heart-AKI (NCT02364427)
- Testing
- Arterial stiffness - Vicorder to measure pulse wave velocity
- Where
- United Kingdom
- Volunteers
- 180 people
- Sponsor
- King's College Hospital NHS Trust
Renal Injury, Anesthesia
Cardiac and Renal Biomarkers in Arthroplasty Surgery
The investigators will compare the effect of spinal anesthesia to general anesthesia on the level of high sensitivity cardiac biomarkers in patients undergoing hip or knee arthroplasty.
- Conditions
- Renal Injury, Anesthesia, Myocardial Injury, Arthropathy of Knee
- Trial name
- NCT03940651
- Testing
- Spinal Anesthesia, General Anesthetics
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Washington University School of Medicine
Postoperative Airway Complications, Postoperative Sore Throat
Continuous Endotracheal Tube Cuff Pressure Monitoring and Postoperative Airway Complications in Laparoscopic Surgery
This prospective randomized controlled study evaluated the effects of different endotracheal tube cuff pressure monitoring strategies on postoperative airway complications in patients undergoing elective laparoscopic abdominal…
- Conditions
- Postoperative Airway Complications, Postoperative Sore Throat, Endotracheal Tube Cuff Pressure
- Trial name
- NCT07485972
- Testing
- Intermittent cuff pressure monitoring, Continuous cuff pressure monitoring, Cuff-leak technique
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Cukurova University
Mandible; Deformity, Surgical Healing
LLLT Effects on Inferior Alveolar Nerve (IAN) Recovery Post-orthognathic Surgery
Low-level laser therapy (LLLT) is a well-studied technique that has been shown to improve recovery time and reduce pain and swelling in patients undergoing surgery, including orthognathic surgery, and has no known negative…
- Conditions
- Mandible; Deformity, Surgical Healing, Orthognathic Surgery, Nerve Injury
- Trial name
- NCT04910074
- Testing
- Low-level laser therapy, Dummy LLLT
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Recurrent Patellar Dislocation, Patellar Instability
The Comprehensive Assessment in Children After Surgical Treatment of Patellar Recurrent Dislocation.
The aim of this prospective study is to assess extension apparatus function of the knee based on clinical, radiological, isokinetic and gait analysis data in patients after surgical treatment.
- Trial name
- NCT03983213
- Testing
- mpfl reconstruction
- Where
- Poland
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Polish Mother Memorial Hospital Research Institute
Post Operative Pain
Comparison of Analgesic Efficacy of Suprainguinal Fascia Iliaca and Quadro-iliac Blocks in Hip Fracture Surgery
This prospective, randomized, double-masked trial compared two ultrasound-guided regional analgesic techniques, suprainguinal fascia iliaca block (SIFI) and quadro-iliac plane block (QIPB), in adults undergoing surgery for hip…
- Trial name
- NCT07546903
- Testing
- Suprainguinal Fascia Iliaca Block, Quadro-Iliac Plane Block
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people
- Sponsor
- Hitit University
Surgical Wound Infection, Cesarean Wound; Dehiscence
Sucrose as a Standard in Cesarean Section Surgical Wound Healing to Reduce Hospital Time
It is a randomized, single-blind clinical trial, whose population to be studied will be randomized patients with a diagnosis of dehiscence and infection of a cesarean surgical wound who meet the inclusion and exclusion criteria.
- Trial name
- SAGRA (NCT06477770)
- Testing
- Clorhexidine soap, Sucrose
- Where
- Honduras
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
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