Clinical trials: Surgical Emergencies, active
Difficult Airway Management
Prediction of Difficult Mask Ventilation in Obese Population Undergoing Emergency Surgery
The current study is an observational, prospective study. It will be conducted in the emergency operative theatre, Alfayoum University, Alfayoum, Egypt.
- Trial name
- NCT07887503
- Volunteers
- 550 people
- Sponsor
- Minia University
Large Bowel Obstruction
International Multi-center Profile of Emergency Large-Bowel Obstruction Management and Outcomes
Mechanical large-bowel obstruction is a common and high-risk emergency surgical condition with substantial variation in diagnostic evaluation, operative timing, and management strategies across institutions and healthcare…
- Trial name
- IMPEL (NCT07458867)
- Volunteers
- 500 people
- Sponsor
- European Society for Trauma and Emergency Surgery
Paracetamol, Hypotension Drug-Induced
Hemodynamic Effects of Intravenous Paracetamol in Patients Undergoing Emergency Laparotomy
Emergency laparotomy is a high-risk procedure often performed in patients with severe physiological derangements due to sepsis, making perioperative management challenging.
- Conditions
- Paracetamol, Hypotension Drug-Induced, Emergency Surgery
- Trial name
- NCT07466108
- Testing
- Paracetamol (acetaminophen)
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Pulmonary Aspiration, Emergency Surgery
Aspiration Risk Assessment by Gastric Ultrasound in eMErgency Surgery and ANesThetic Decision-making: The ARGUMENT Study
Pulmonary aspiration of gastric contents is a serious patient safety problem accounting for 50% of anesthesia-related mortality.
- Trial name
- NCT06303492
- Testing
- GUS
- Where
- Canada
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Quality of Life (QOL), Decision Making
Peri-Operative Surgical Care Optimisation for Patients Requiring Emergency Surgery
Emergency General Surgery (EGS) is an umbrella term which describes all patients presenting to hospital with an acute abdominal problem. Patients can have various conditions requiring emergency operations.
- Conditions
- Quality of Life (QOL), Decision Making, Emergency General Surgery
- Trial name
- PERI-SCOPES (NCT06972017)
- Volunteers
- 112 people
- Sponsor
- NHS Greater Glasgow and Clyde
Linea Alba Hernia, Evisceration; Operation Wound
Influence of Suture Type on Emergency Midline Laparotomy Closure
There is no clear recommendation in international guidelines regarding the type of suture to be used for closing emergency midline laparotomies.
- Conditions
- Linea Alba Hernia, Evisceration; Operation Wound, Suture; Complications, Mechanical
- Trial name
- NCT06865807
- Testing
- PDS 2/0 vs Monomax 2/0
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Hospital San Juan de Dios Tenerife
Surgical Site Infection (SSI), Emergency Laparotomies
The Spotlight Study: Early Identification of Post-Surgical Infections Using Bedside Ultrasound.
Introduction: The goal of this observational study is to learn whether point-of-care ultrasound (POCUS) can help detect early fluid build-up under the skin after open abdominal surgery (laparotomy) and whether these findings can…
- Conditions
- Surgical Site Infection (SSI), Emergency Laparotomies, Point of Care Ultrasound (POCUS)
- Trial name
- SPOTLIGHT (NCT07549880)
- Testing
- Point-of-Care Ultrasound (POCUS), Microbiological Wound Swab, ASEPSIS Wound Assessment
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Slagelse Hospital
Emergency General Surgery
Robotic Emergency General Surgery Program
Background Abdominal surgical emergencies account for 20-30% of visceral surgery procedures. However, these emergencies are responsible for more than half of the morbidity in our discipline, with a surgical site infection rate…
- Trial name
- NCT07202442
- Testing
- Emergency General surgery patients with robotic approach for the surgery
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Emergence Delirium, Anesthesia
Effect of Different Drugs on Emergency Delirium in Preschool Age Patient
Emergence delirium (ED) was first described by Eckenhoff and colleagues in the 1960s and is defined in pediatric anesthesia as 'dissociated state of consciousness in which child is irritable, uncompromising, uncooperative…
- Trial name
- NCT07057193
- Testing
- Dexmedetomidine group (D group), Ketamine group (K group), Midazolam group (M group)
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cholecystitis, Acute, Cholecystectomy, Laparoscopic
Implementation of RICA (ERAS) Guidelines in Grade II Acute Cholecystitis Undergoing Early Laparoscopic Cholecystectomy
Background Acute cholecystitis (sudden gallbladder inflammation, usually due to gallstones) is a highly frequent surgical emergency.
- Conditions
- Cholecystitis, Acute, Cholecystectomy, Laparoscopic, Enhanced Recovery After Surgery
- Trial name
- COLERICA II (NCT07695922)
- Testing
- RICA Perioperative Care Pathway
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- Hospital d'Igualada
Acute Kidney Injury, Intra-Abdominal Hypertension
Cumulative Intra-Abdominal Pressure Burden and Acute Kidney Injury After Emergency Abdominal Surgery
The goal of this observational study is to learn whether increased pressure inside the abdomen over time is associated with acute kidney injury in adults receiving intensive care after emergency abdominal surgery.
- Trial name
- IAP-AKI (NCT07891026)
- Testing
- Serial Intra-Abdominal Pressure Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people
- Sponsor
- Ugur Duman
Abdomen, Acute
Clinical Outcomes and Equality in Healthcare for Emergency General Surgery Patients Undergoing Emergency Laparotomy
The goal of this observational cohort study is to evaluate the standard of care for general surgerical patients undergoing emergency laparotomy and assess factors affecting clinical outcomes, as well as evaluating the quality of…
- Trial name
- LAPTOP (NCT05623176)
- Testing
- Standardised laparotomy care
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Stockholm
Postoperative Complication, Respiratory Complications
Real-time Evaluation and Continuous Observation of Vital Signs for Enhanced Recovery: a Study for the Early Identification of Complications in the Surgical Ward Following Surgery in Patients Not Eligible for Intensive Care Admission.
This study aims to evaluate whether continuous vital sign monitoring with wearable devices can help detect postoperative complications in surgical ward earlier than standard hospital monitoring.
- Conditions
- Postoperative Complication, Respiratory Complications, Cardiac Complications
- Trial name
- RECOVER (NCT07729891)
- Testing
- Continuous vital sign monitoring with Portrait Mobile in surgical ward
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Ospedaliero-Universitaria di Parma
Suture Techniques, Wound Closure Techniques
Small Bites Vs Large Bites Abdominal Midline Incisional Closure
The goal of this trial is to compare the effectiveness of small bite versus large bite abdominal incision closure in emergency settings. It will also evaluate the safety and outcomes of each technique.
- Conditions
- Suture Techniques, Wound Closure Techniques, Laparotomy/Standerds, Surgical Wound Dehiscence
- Trial name
- NCT07154277
- Testing
- Small bite closure, Large bite closure
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Dow University of Health Sciences
Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment
China Research for Severe Spontaneous Intracerebral Hemorrhage（CRISIH）
Background: Although emergency surgery may reduce mortality in patients with severe spontaneous intracerebral hemorrhage (SSICH), the effectiveness and safety of surgical treatment among SSICH patients receiving long-term oral…
- Conditions
- Severe Spontaneous Intracranial Hemorrhage, Long-term Antiplatelet Treatment, Emergency Surgery, Complications
- Trial name
- NCT05975398
- Testing
- Emergency neurosurgery, Conservative treatment
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Beijing Tiantan Hospital
Emergency Abdominal Surgery
Physiotherapy After Emergency Laparotomy in the Elderly
Emergency laparotomy is associated with high postoperative morbidity and mortality. This risk is particularly high among elderly patients, who often present with reduced physiological reserve, frailty, and multimorbidity.
- Trial name
- NCT07504185
- Testing
- Experimental (Structured postoperative physiotherapy), Standard postoperative care
- Where
- Cyprus
- Volunteers
- 250 people
- Sponsor
- University of Cyprus
Emergencies
Nomogram for Predicting Difficult Laparoscopic Appendectomy
No prior studies have stratified the difficulty of laparoscopic appendectomy (LA). The investigators aimed to investigate preoperative factors as indicators of difficult LAs based on the experience of surgical trainees and to…
- Trial name
- NCT06818942
- Testing
- Observations on preoperative and intraoperative factors influencing the difficulty of surgery
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Shanghai 6th People's Hospital
Arteriovenous Malformation, Bleeding
Clinical Study on Emergency Treatment of Cerebral Arteriovenous Malformation Bleeding
Cerebral arteriovenous malformation (AVM) is the leading cause of brain hemorrhage in young adults, characterized by sudden onset and rapid progression.
- Trial name
- NCT07118631
- Where
- China
- Volunteers
- 162 people
- Sponsor
- Beijing Tiantan Hospital
Acute Appendicitis, Acute Cholecystitis
Web-based International Register of Emergency Surgery and Trauma
The WIRES-T project (Web-based International Registry of Emergency General Surgery and Trauma) has been set up to allow to all the EGS (Emergency General Surgery) and Trauma surgeons to register their activity and to obtain a…
- Conditions
- Acute Appendicitis, Acute Cholecystitis, Acute Diverticulitis, Post-operative Complications
- Trial name
- WIRES-T (NCT03643718)
- Testing
- Emergency General Surgery
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Digestive Emergency, New Pathway
Effectiveness of the RAUC Pathway in Reducing Unscheduled Hospitalizations After Emergency Digestive Surgery
The number of emergencies's visits (22 million visits in 2019 in France), the organization of emergencies and the sustainability of the current health system are threatened.
- Conditions
- Digestive Emergency, New Pathway, Connected Health
- Trial name
- RAUCAMIENS (NCT06769438)
- Testing
- ERAS, DEEPSEN, RDS
- Where
- 6 sites in France
- Volunteers
- 3,048 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens