Clinical trials: Surgery, Laparoscopic
Dexmedetomidine, Total Intravenous Anesthesia
The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption
Opioids analgesic are the gold standard for intraoperative pain management. Their short- and long-term adverse effect motivate anesthesiologists to explore opioid sparing strategies.
- Conditions
- Dexmedetomidine, Total Intravenous Anesthesia, Remifentanil Consumption, Remifentanil
- Trial name
- DEXREM (NCT06684197)
- Testing
- Dexmedetomidine
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Laparoscopic Surgery, Visceral Pain, Postoperative
Anrikefon-based Patient-controlled Intravenous Analgesia Following Laparoscopic Surgery
Visceral pain following laparoscopic surgery is frequently underestimated, yet it is associated with a range of adverse outcomes.
- Conditions
- Laparoscopic Surgery, Visceral Pain, Postoperative, Anrikefon, Patient-controlled Intravenous Analgesia
- Trial name
- NCT07525986
- Testing
- High-dose anrikefon, Medium-dose anrikefon, Low-dose anrikefon
- Where
- 4 sites in China
- Volunteers
- 140 people
- Sponsor
- Peking University First Hospital
Recovery, Analgesia And Delirium Profiles At Laparoscopic Abdominal and Gynecologic Surgeries With Processed EEG Monitoring
Recovery, Analgesia And Delirium Profiles At Laparoscopic Abdominal and Gynecologic Surgeries With Processed EEG Monitoring
The aim of this study is to evaluate the effects of processed electroencephalogram (pEEG) monitoring on recovery and extubation times, length of stay in the post-anesthesia care unit (PACU), postoperative pain, patient comfort…
- Trial name
- TandRT (NCT07670689)
- Testing
- Bispectral index monitoring
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Cukurova University
Laparoscopic Cholecystectomy Surgery
Effects of the 4-7-8 Breathing Technique on Postoperative Pain Scores, Anxiety, and Sleep Quality in Patients
This study aims to evaluate the effects of teaching the 4-7-8 breathing technique, one of the deep breathing techniques, to patients undergoing laparoscopic cholecystectomy surgery and applying it during the preoperative and…
- Trial name
- NCT07303634
- Testing
- 4-7-8 Breathing Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Konya Beyhekim Training and Research Hospital
Intravenous Lidocaine, Laparoscopic Surgery
Intravenous Lidocaine Plus Port-Site Ropivacaine for Recovery After Laparoscopic Surgery
This randomized controlled trial evaluates whether perioperative intravenous lidocaine infusion, combined with port-site ropivacaine infiltration, improves postoperative recovery after laparoscopic abdominal surgery.
- Conditions
- Intravenous Lidocaine, Laparoscopic Surgery, Post Operative Recovery, Local Anaesthetic Systemic Toxicity
- Trial name
- LivQor (NCT07414706)
- Testing
- Procedure/Standard care, ropivacaine, Lidocaine (intravenous infusion, perioperative)
- Where
- France
- Volunteers
- 182 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Appendectomy, Laparoscopic, Acute Appendicitis
Feasibility and Safety of a Pediatric ERAS Protocol for Laparoscopic Appendectomy
Acute appendicitis is the most common surgical emergency in children. Despite the widespread adoption of laparoscopic appendectomy, postoperative care still varies widely between institutions, with prolonged fasting, opioid-based…
- Conditions
- Appendectomy, Laparoscopic, Acute Appendicitis, Pediatric Surgery, ERAS
- Trial name
- NCT07643285
- Testing
- Comprehensive 20-Item Pediatric ERAS Protocol
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ahmet Burak Doğan, MD
Postoperative Pain, Laparoscopic Cholecystectomy Surgery
Impact of Video-Based Patient Education on Physician Trust, Pain, and Anxiety in Laparoscopic Cholecystectomy
This prospective, randomized, single-center, single-blind study aims to evaluate the effects of video-based preoperative education on physician trust, postoperative pain, anxiety, and opioid consumption in patients undergoing…
- Conditions
- Postoperative Pain, Laparoscopic Cholecystectomy Surgery, Preoperative Anxiety, Trust in Healthcare System
- Trial name
- VITAP (NCT07767344)
- Testing
- Video-Based Preoperative Block Education, Standard Verbal Preoperative Block Education
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people
- Sponsor
- Sanliurfa Education and Research Hospital
Abdominal Laparoscopic Surgery
Application of the Maestro Surgical System for Surgical Assistance in Laparoscopic Abdominal Surgery
This study is designed to evaluate the application of the Maestro Robotic Platform for surgical assistance in laparoscopic abdominal surgery.
- Trial name
- MAESTRO (NCT07858929)
- Testing
- Any abdominal laparoscopic surgery with the usage of the Maestro Platform.
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Portsmouth Hospitals NHS Trust
Laparoscopic Cholecystectomy Surgery, Perioperative Analgesia
Comparison of M-TAPA and External Oblique Intercostal Block for Intraoperative Opioid Consumption in Laparoscopic Cholecystectomy
This prospective, randomized, interventional study compares the effects of modified thoracoabdominal nerve block through perichondrial approach (M-TAPA) and external oblique intercostal plane block (EOI) on intraoperative…
- Trial name
- MTAPA-EOI (NCT07595679)
- Testing
- Modified Thoracoabdominal Nerve Block Through Perichondrial Approach (M-TAPA), External Oblique Intercostal Plane Block (EOI)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ankara Etlik City Hospital
Retrolaminar Block, TAP Block
Ultrasound Guided Retrolaminar Block Versus Transverse Abdominis Plane Block in Laparoscopic Upper Abdominal Surgeries
This study aims to compare and evaluate the safety and efficacy of ultrasound guided retrolaminar block versus transverse abdominis plane block in laparoscopic upper abdominal surgeries.
- Conditions
- Retrolaminar Block, TAP Block, Laparoscopic Abdominal Surgeries
- Trial name
- NCT07720817
- Testing
- Ultrasound-guided Retrolaminar Block group, Transverses Abdominis Plane (TAP) Block Group
- Where
- Egypt
- Volunteers
- 164 people
- Sponsor
- Mansoura University
Laparoscopic Surgery
Laparoscopic Skills Acquisition Using an AI-enhanced Game-based Simulation Tool Compared With a Laparoscopic Simulator Box Trainer
The goal of this clinical trial is to learn whether an AI-enhanced, game-based laparoscopic simulation tool can improve laparoscopic skills training and help increase surgical capacity in surgical trainees and other healthcare…
- Trial name
- CAMELs-RCT (NCT07276022)
- Testing
- AI-enhanced game-based simulation tool (Laptitude), Laparoscopic simulator box trainer (SurgTrac)
- Where
- 3 sites in Guatemala, India and 1 more
- Volunteers
- 157 people
- Sponsor
- University of Edinburgh
Laparoscopic Surgery, Post Operative Pain, Acute
Maneuvers to Reduce Laparoscopic Pain
Laparoscopic surgery has revolutionized surgical care by reducing morbidity and improving post operative recovery. Laparoscopic surgery involves the use of carbon dioxide for insufflation to achieve optimal visualization.
- Conditions
- Laparoscopic Surgery, Post Operative Pain, Acute, Pneumoperitoneum
- Trial name
- NCT07583433
- Testing
- Smoke Evacuation Group, Recruitment Breath Group, Control Group
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Hemodynamics Instability, Pain After Surgery
Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients
The goal of this triple blinded randomized control trial is to compare the effect of magnesium sulphate on the hemodynamic response during pneumoperitoneum creation, along with its impact on postoperative pain, opioid…
- Conditions
- Hemodynamics Instability, Pain After Surgery, PONV in Laparoscopic Cholocystectomies
- Trial name
- NCT07079514
- Testing
- Magnesium
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziauddin University
Patients Undergoing Major Laparoscopic Abdominal Surgery
Intrathecal Morphine for Postoperative Analgesia in Major Laparoscopic Abdominal Surgery, a IMPACT-Scope Trial
The goal of this clinical trial is to learn the clinical and cost effectiveness of intrathecal morphine (ITM) in addition to usual care as a postoperative pain relief strategy following major laparoscopic abdominal surgery…
- Trial name
- IMPACT-Scope (NCT06666985)
- Testing
- ITM + Usual Care
- Where
- China
- Volunteers
- 700 people
- Sponsor
- First Affiliated Hospital, Sun Yat-Sen University
Hysterectomy, Laparoscopic Surgery
Ureterolysis in Laparoscopic Total Hysterectomy: Routine Approach
This randomized controlled trial will compare routine bilateral ureterolysis with selective ureterolysis during total laparoscopic hysterectomy for benign gynecological conditions.
- Trial name
- ULTRA (NCT07774858)
- Testing
- Routine Ureterolysis, Selective Ureterolysis
- Where
- Egypt
- Volunteers
- 35,000 people
- Sponsor
- ClinAmygate
Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Increase
Assessment of Optic Sheat Diameter (ONSD) and Eyeball Transverse Diameter (ETD) Ratio Measurement From Ocular Ultrasound
The aim of this study is to evaluate the effects of different carbon dioxide gas insufflation pressures on the ultrasound-guided optic nerve sheath diameter in patients undergoing laparoscopic cholecystectomy and to determine the…
- Conditions
- Optic Nerve Sheath Diameter Measurement, Intracranial Pressure Increase, Laparoscopic Cholecystectomy Surgery
- Trial name
- ONSD ETD (NCT07784361)
- Testing
- Low Pressure Group, High Pressure Group
- Volunteers
- 68 people
- Sponsor
- Gaziantep City Hospital
Abdominal Laparoscopic and/or Robotic Surgery, Local Anasthesia
Intraperitoneal Lidocaine and Bupivacaine for Postoperative Pain After Laparoscopic Surgery
The goal of this clinical trial is to determine the safety and efficacy of combined intraperitoneal local anesthetic instillation and port-site infiltration using lidocaine and bupivacaine in adults aged 18 to 60 undergoing…
- Conditions
- Abdominal Laparoscopic and/or Robotic Surgery, Local Anasthesia, Post Operative Pain, Acute, Lidocaine
- Trial name
- IPLA (NCT07775599)
- Testing
- Lidocaine, Bupivacaine
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Misr University for Science and Technology
Laparoscopic Colorectal Surgery
Oxygen Reserve Index in Laparoscopic Colorectal Surgery
During laparoscopic procedures, certain physiological changes occur due to the creation of pneumoperitoneum. One such change is the reduction in portal venous blood flow, which can lead to decreased liver perfusion and acute…
- Trial name
- NCT07445698
- Testing
- Oxygen Administration During Extubation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Intracranial Pressure, Laparoscopic Surgery
Comparison of the Effects of Sevoflurane and Desflurane on Optic Nerve Sheath Diameter During Laparoscopic Surgery
Laparoscopic surgeries require pneumoperitoneum and Trendelenburg position, which may lead to increased intracranial pressure (ICP).
- Conditions
- Intracranial Pressure, Laparoscopic Surgery, Optic Nerve Sheath Diameter
- Trial name
- NCT07525648
- Testing
- Sevoflurane, Desflurane
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Medipol University
Laparoscopic Surgery Simulation, Mental Workload
Impact of Preferred Music on Laparoscopic Task Performance and Mental Workload in Novice Surgeons
This single-blinded, three-arm randomized controlled trial evaluated the effects of different auditory environments on laparoscopic task performance and mental workload among novice surgeons in a simulated setting.
- Conditions
- Laparoscopic Surgery Simulation, Mental Workload, Stress, Psychomotor Performance
- Trial name
- NCT07738848
- Testing
- Behavioral: Preferred Music, White Noise, SIlent Control
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Universiti Sains Malaysia