Clinical trials: Sun Damaged Skin
Aging, Skin Abnormalities
Efficacy of Polypodium Leucotomos Extract Decreasing UVA Premutagenic and Photoaging Markers
With this study, the investigators will like to determine if taking a dose of the study medication, called Polypodium leucotomos (PL), prevents some of the changes in the skin caused by the adverse effects of UVA, a type of…
- Trial name
- NCT00520910
- Testing
- Polypodium leucotomos
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Tobacco Use Cessation, Smoking Cessation
Evaluating the Impact of a Photoaging App Versus School-Based Educational Intervention on Adolescents' Knowledge, and Attitudes Towards Tobacco Use
Tobacco use is a leading cause of preventable morbidity and mortality worldwide. It has been estimated that by 2030, tobacco use will cause approximately 10 million deaths per year worldwide, with 70% of those occurring in low…
- Conditions
- Tobacco Use Cessation, Smoking Cessation, Smoking Prevention
- Trial name
- NCT06483763
- Testing
- SmokerFace App from the Education Against Tobacco (EAT) program, The use of standardized school-based educational module
- Where
- Oman
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Sultan Qaboos University
Photoaging
Efficacy of Fractional Microneedle Radiofrequency and Fractional Erbium-Doped Glass 1,565-nm for Baggy Lower Eyelids
The purpose of this study was to compare the efficacy and safety of FMR and NAFL in the treatment of baggy lower eyelids(BLEs)
- Trial name
- NCT04237324
- Testing
- Treatment one side BLE by NAFL, Treatment another side BLE by FMR
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Xijing Hospital
Skin Health
To Determine the Activity and Mechanisms of Cranberries to Attenuate Skin Photoaging and Improve Skin Health in Women
Previous studies have shown that cranberry phytochemicals scavenge reactive carbonyls. Cranberry polyphenols have been reported to attenuate collagen degradation and inhibit oxidative stress in human cells.
- Trial name
- NCT04183920
- Testing
- Cranberry juice
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Florida
Sun-Damaged Skin, Retinoid Intolerance
The Effect Of A Controlled Daily Skin Care Regimen On Retinoic Acid Tolerance
Sun-damaged skin, caused by chronic exposure to ultraviolet (UV) light, is characterized by features such as wrinkling, uneven skin color, roughness and brown spots.
- Trial name
- NCT00440024
- Testing
- Tazorac, Dove Mild Cleanser, Dove Facial Moisturizer
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Facial Photoaging, Deepening of Facial Wrinkles
Regenmedic Cream 2.0 12-week Long-term Clinical Test
The goal of this study is to evaluate the anti-wrinkle, firming, moisturizing and repairing efficacy of a test facial cream after single use and 12 weeks of continuous use via clinical evaluation, instrumental measurement, image…
- Conditions
- Facial Photoaging, Deepening of Facial Wrinkles, Skin Laxity, Decreased Skin Elasticity
- Trial name
- NCT07874113
- Testing
- Test facial cream (topical skin care product)
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Skin Aging, Photoaging of Skin
Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules
This is a placebo-controlled blinded clinical evaluation of day and night skin care creams supplemented by Medicell Technology's composition of defensins and supportive molecules determine the skin hydration and anti-aging…
- Trial name
- NCT02765763
- Testing
- 2-Minute Reveal Masque, 24/7 Barrier Repair Cream, 8-in-1 BioSerum
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Advanced Dermatology
Photodamage, Photoaging
Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage
This is a randomized, comparative, single evaluator-blinded trial to evaluate clinical, histological and immunohistochemical effects of oral isotretinoin plus moisturizer sunscreen as compared to the use of 0,05% tretinoin cream…
- Trial name
- NCT00842907
- Testing
- oral isotretinoin, Tretinoin
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Vascular Lesions, Photoaging
VELOS for the Treatment of Vascular Lesions and Skin Rejuvenation
This is a multi-center, multi-cohort, prospective, open-label study of VELOS for treatment of vascular skin disorders. The plan is to enroll up to 60 subjects from up to 3 centers in the US and worldwide.
- Trial name
- NCT02468453
- Testing
- velos
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Moderate-severe Skin Aging/Photoaging
Efficacy and Tolerance Evaluation of an Anti-age Food Supplement
Efficacy and Tolerance Evaluation of an Anti-age Food Supplement: a Randomized, Controlled Clinical Study Versus Untreated Group
- Trial name
- NCT03274154
- Testing
- Pre-Hyaluron 465 Innēov
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-Fractional Laser for Facial Rejuvenation
This randomized, multi-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after hybrid-fractional…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06436261
- Testing
- Hybrid Fractional Laser, Facial Cleanser, Facial Moisturizer
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photoaging
Platelet Rich Fibrin Versus Platelet Rich Plasma for Microneedling Treatment of Facial Photoaging
The present study was conducted for analyzing the efficacy and safety of platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) in photoaging therapy. Specific arms: 1.
- Trial name
- NCT06452667
- Testing
- platelet-rich fibin, platelet-rich palsma
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Skin, Skin Ageing
Clinical Trial to Assess the Efficacy and Safety of a Cosmetic Product in Individuals Showing Signs of Cutaneous Aging.
This clinical study investigates the effects and safety of a topical cosmetic product containing postbiotics (Bifida ferment extract and Pediococcus ferment extract) in women aged 35-60 with visible signs of skin aging.
- Conditions
- Skin, Skin Ageing, Fine Lines, Face Aging/Photo Aging of Moderate Grade
- Trial name
- SkinMeter (NCT07343544)
- Testing
- Active cream
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Skin Photoaging
Efficacy and Tolerance Evaluation of an Amino Acid Food Supplement
Skin moisturizing and elasticizing efficacy of an amino acid food supplement
- Trial name
- NCT03801343
- Testing
- Nutrakos®
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Photoaging, Epidermal p53 Expression
Oral Isotretinoin for Photoaging: Results of a Randomized Controlled Phase II Trial
A clinical and histological randomized controlled phase II trial to evaluate the efficacy and safety of oral isotretinoin for treating photoaging was performed with 32 menopausal or sterilized women aged 40-55y.
- Trial name
- NCT00701740
- Testing
- oral isotretinoin and Mexoryl SX / XL, Mexoryl XL / SX
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Federal University of São Paulo
Wrinkles, Photoaging
Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and…
- Conditions
- Wrinkles, Photoaging, Fine Lines
- Trial name
- NCT05089851
- Testing
- Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Actinic Keratosis, Photoaging
Photodynamic Therapy (PDT) Effect on Large Surface Photodamaged Skin
In this study, 26 patients were selected and included for full-face photodynamic therapy sessions. All patients presented signs of photoaging skin and multiple actinic keratosis.
- Conditions
- Actinic Keratosis, Photoaging, Solar Elastosis
- Trial name
- PDT (NCT00843323)
- Testing
- Methylaminolevulinate - photodynamic therapy
- Volunteers
- 26 people
- Sponsor
- University of Sao Paulo
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation
This randomized, single-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after fractional ablative…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06366503
- Testing
- Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Aging, Skin Rejuvenation
Comparative Study of a 1064-nm Fractional Picosecond Laser Versus IPL in Facial Rejuvenation
This is a single-center, prospective, randomized controlled trial conducted at Huashan Hospital, Fudan University. The purpose of this study is to compare the effectiveness and safety of two non-invasive treatment options-1064-nm…
- Conditions
- Skin Aging, Skin Rejuvenation, Photoaging
- Trial name
- NCT07122310
- Testing
- 1064-nm Fractional Picosecond Laser (PicoWay), Intense Pulsed Light Therapy (M22 IPL System)
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Sun Damaged Skin
Photoprotective Effects of a SPF50+ Sunscreen on Skin Genotoxicity Induced by Repeated Chronic Outdoor Sun Exposure
Between 2 and 3 million non-melanoma skin cancers and 132,000 melanoma skin cancers occur globally each year. Sun protection continues to be a major public health issue and has always been a priority research area for Pierre…
- Trial name
- NCT05926791
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique