Clinical trials: Sun Damaged Skin
Sun Damaged Skin
Photoprotective Effects of a SPF50+ Sunscreen on Skin Genotoxicity Induced by Repeated Chronic Outdoor Sun Exposure
Between 2 and 3 million non-melanoma skin cancers and 132,000 melanoma skin cancers occur globally each year. Sun protection continues to be a major public health issue and has always been a priority research area for Pierre…
- Trial name
- NCT05926791
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Photoaging
Photoaging Treatment With Imiquimod
Recently it was demonstrated that imiquimod in addition to exerting a repairing effect in pre malignant and malignant lesions caused by UV radiation it reverses histopathological changes associated with the photoaging skin.
- Trial name
- NCT01935310
- Testing
- Imiquimod
- Where
- Colombia
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- CES University
Wrinkle, Photoaging
Comparison of the Cosmetic Effects of Bakuchiol and Retinol
Subjects will be assigned to a retinoid cream or bakuchiol to compare the cosmetic effects. This will take place over a 12 week period.
- Trial name
- NCT03112863
- Testing
- Bakuchiol, Retinol
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Aging, Skin Abnormalities
Efficacy of Polypodium Leucotomos Extract Decreasing UVA Premutagenic and Photoaging Markers
With this study, the investigators will like to determine if taking a dose of the study medication, called Polypodium leucotomos (PL), prevents some of the changes in the skin caused by the adverse effects of UVA, a type of…
- Trial name
- NCT00520910
- Testing
- Polypodium leucotomos
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Miami
Photoaging
The Effects of a Longevity Supplement on Aging and Photoaging
This study evaluates the use of an oral supplement to see if it can shift the function of the skin and the appearance of fine lines and wrinkles, its impact on biomarkers associated with aging, and its impact on mental health.
- Trial name
- NCT05262036
- Testing
- Anti-aging Supplement
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Skin Photoaging
Efficacy and Tolerance Evaluation of an Amino Acid Food Supplement
Skin moisturizing and elasticizing efficacy of an amino acid food supplement
- Trial name
- NCT03801343
- Testing
- Nutrakos®
- Where
- Italy
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Wrinkle, Photoaging
An Exploratory Investigation of a Novel Skincare Regimen
This trial will assess the effectiveness of the Aria Trio Complete Facial system in being able to reduce blemishes, lines, and wrinkles.
- Conditions
- Wrinkle, Photoaging, Acne, Skin Inflammation
- Trial name
- NCT05517720
- Testing
- Aria Trio complete Facial System
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Trophy Skin
Skin Aging, Skin Rejuvenation
Comparative Study of a 1064-nm Fractional Picosecond Laser Versus IPL in Facial Rejuvenation
This is a single-center, prospective, randomized controlled trial conducted at Huashan Hospital, Fudan University. The purpose of this study is to compare the effectiveness and safety of two non-invasive treatment options-1064-nm…
- Conditions
- Skin Aging, Skin Rejuvenation, Photoaging
- Trial name
- NCT07122310
- Testing
- 1064-nm Fractional Picosecond Laser (PicoWay), Intense Pulsed Light Therapy (M22 IPL System)
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Huashan Hospital
Aging Skin, Body Mass Index
Clinical Profile of Skin Aging Based on Dermoscopy Photoaging Scale and Glogau Scale - Study of Leucocyte Telomere Length, Biomarker P16, and Body Mass Index
To determine the relationship between clinical appearance, dermoscopic examination results of photoaging profiles based on clinical examination, DPAS score and leucocyte telomere length, to analyze the relationship between BMI…
- Conditions
- Aging Skin, Body Mass Index, Cellular Senescence, Triglycerides
- Trial name
- LTLP16 (NCT06779032)
- Testing
- blood draw
- Where
- Indonesia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Skin Aging, Photoaging of Skin
Clinical Evaluation of Day and Night Skin Care Creams Supplemented With MediCell Technology (MCT)'s Composition of Defensins and Supportive Molecules
This is a placebo-controlled blinded clinical evaluation of day and night skin care creams supplemented by Medicell Technology's composition of defensins and supportive molecules determine the skin hydration and anti-aging…
- Trial name
- NCT02765763
- Testing
- 2-Minute Reveal Masque, 24/7 Barrier Repair Cream, 8-in-1 BioSerum
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Advanced Dermatology
Face Skin Photoaging
Face Photoaging: Efficacy and Tolerance Evaluation of an Intradermal Injective Treatment
Efficacy and tolerance evaluation of an intradermal injective treatment
- Trial name
- NCT03274232
- Testing
- SUNEKOS ® 200
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Sun Damaged Skin
Efficacy Evaluation of Products Against Long Wavelength Ultraviolet A1 and Visible Light Induced Biological Effects
The purpose of this study is to evaluate the efficacy of topical products in providing protection against the visible light and ultraviolet A1 (UVA1) part of sunlight.
- Trial name
- NCT04181476
- Testing
- Sunscreening Agents
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Skin Diseases, Photoaging
Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida.
- Conditions
- Skin Diseases, Photoaging, Skin Hydration
- Trial name
- DCHA-FL-25-65 (NCT07764809)
- Testing
- BT-Analyze bioimpedance skin hydration measurement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care
Photoaged Skin, Normal Skin
Immunologic Profile of Chronically Photodamaged Skin
Chronically photodamaged skin is visually characterized by dryness, wrinkles, brown spots, leathery appearance, etc. This happens as a result of excessive exposure to UV light from the sun.
- Trial name
- NCT02889159
- Testing
- Candida albicans antigen, histamine phosphate, imiquimod 5% cream
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Photoaging
Evaluation of Hexyresorcinol vs Hydroquinone for Photoaging
Photoaging is a common concern within the cosmeceutical industry with many products that are available. One frequently used product is hydroquinone that is used to even skin tone. However, hydroquinone has several shortcomings.
- Trial name
- NCT04345094
- Testing
- Hexylresourcinol, Hydroquinone
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Sytheon Ltd.
Tobacco Addiction, Smoking Related Diseases
A Photoaging Mobile App Promoting Poster Campaign for Preventing Smoking in Secondary Schools
The purpose of this study is to determine whether photoaging mobile app promoting poster campaigns are effective to reduce smoking prevalence among adolescents in Germany. This is measured via questionnaire.
- Conditions
- Tobacco Addiction, Smoking Related Diseases, Adolescent Smoking
- Trial name
- Smokerface (NCT02544360)
- Testing
- Photoaging mobile app promoting poster campaign.
- Where
- Germany
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Photoaging
Double-Blind Study Determining the Efficacy of CannaXR in Decreasing UVA Premutagenic and Photoaging Markers
Ultraviolet light A (UVA) causes oxidization of guanine to mutagenic 8-Oxoguanine (8-OxoG) and the most frequent and best characterized mutation in mitochondrial DNA (mtDNA), a deletion of 4,977 base pairs, called the "common…
- Trial name
- CNXR-001D (NCT05279495)
- Testing
- In a double-blinded fashion, 250 mg CANNAXR cream, Topical VEHICLE cream
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- MINO Labs, LLC
Photodamage, Photoaging
Efficacy and Safety of Oral Isotretinoin for Cutaneous Photodamage
This is a randomized, comparative, single evaluator-blinded trial to evaluate clinical, histological and immunohistochemical effects of oral isotretinoin plus moisturizer sunscreen as compared to the use of 0,05% tretinoin cream…
- Trial name
- NCT00842907
- Testing
- oral isotretinoin, Tretinoin
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
Skin Quality, Skin Wrinkles
Evaluation of Effects on Skin Quality of a Centella Asiatica Extracellular Vesicle-based Skin Care Formulation.
The study evaluates the effects of a skin care formulation containing Centella asiatica extracellular vesicles as the main active ingredient on facial appearance and skin quality in healthy participants.
- Conditions
- Skin Quality, Skin Wrinkles, Melanin Hyperpigmentation, Skin Hydration
- Trial name
- NCT06850935
- Testing
- Centella asiatica extracellular vesicle formulation
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hungkuang University
Cutaneous Photoaging
Efficacy and Safety of Kinetin 0.1% for Treatment of Skin Photoaging
The purpose of the study is to evaluate the change in the severity and clinical signs of skin photoaging among Filipino patients using Kinerase cream (Kinetin 0.1%).
- Trial name
- NCT01898182
- Testing
- Kinetin, N6-furfuryladenine, 0.1%
- Where
- 2 sites in Philippines
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Makati Medical Center