Clinical trials: Suicide Risk
Depression, Suicidal Ideation
BRITEPath, Component 3 of iCHART (Integrated Care to Help At-Risk Teens)
BRITEPath (BP) aims to support co-located mental health clinicians in the development of a high quality, effective, and personalized safety plan for referred patients who screen positive for depression and/or suicidal ideation.
- Trial name
- NCT04000399
- Testing
- BRITEPath
- Where
- 6 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Pittsburgh
Sleep Disturbance, Sleep
Sleep and Circadian Interventions for College Students at High Risk of Suicide
The purpose of this study is to examine the extent to which delivering sleep and circadian focused interventions in addition to evidenced based psychiatric care for depression and suicide risk may contribute to decreasing suicide…
- Conditions
- Sleep Disturbance, Sleep, Depression, Suicide
- Trial name
- REST-UP (NCT07346014)
- Testing
- Sleep Feedback + Psychoeducation, Transdiagnostic Sleep and Circadian Intervention + Bright Light (TSC+), Triple Chronotherapy (TCT+)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Pittsburgh
Self-Injurious Behavior, Suicidal Ideation
Brief Admission Skane: Replacing General Admission for Individuals With Self-harm and Acute Risk of Suicide
The purpose of the study is to test a standardized version of brief admission (BA) through randomized controlled trial (RCT). The main objective is to evaluate if BA can serve as a crisis management model for individuals with…
- Conditions
- Self-Injurious Behavior, Suicidal Ideation, Suicide, Attempted, Borderline Personality Disorder
- Trial name
- BAS (NCT02985047)
- Testing
- Brief Admission
- Where
- Sweden
- Volunteers
- 125 people
- Sponsor
- Region Skane
Sleep Disorder, Mental Health Issue
Improving Sleep in a Psychiatric Hospital
The purpose of this study is to examine effects of sleep promotion versus treatment as usual (TAU) on subjective, self-reported sleep while in inpatient psychiatric treatment, to examine effects of sleep promotion vs.
- Trial name
- NCT07010718
- Testing
- Scented Oil, Ear Plugs, Eye Mask
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suicidal Ideation
The Impact of Routine Follow-up Contacts After a Pediatric ED Visit for Youth With Suicide Risk
The goal of this clinical trial is to learn if a social work led follow up program helps caregivers of youths with suicide risk access mental health resources. Primary aims include: 1.
- Trial name
- NCT06616701
- Testing
- Follow up call
- Where
- United States
- Volunteers
- 401 people
- Sponsor
- Johns Hopkins University
Military Service Members at Elevated Suicide Risk
Increasing Help-Seeking in Military Service Members
There is sufficient evidence that military service members markedly underutilize behavioral health care services, in part, due to stigma.
- Trial name
- NCT04043936
- Testing
- Cognitive Bias Modification Intervention for Help-Seeking Stigma, Self-Directed Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Florida State University
Child Behavior Disorders, Suicide and Self-harm
iKinnect2.0 for Juvenile Justice Involved Youth at Risk for Suicide
This study is a 16-week intent-to-treat randomized controlled trial (RCT) with 120 suicidal juvenile justice (JJ)-involved transition-age (TA) youth (age 15-21 years) and a primary caregiver (dyads).
- Trial name
- NCT04909203
- Testing
- iKinnect2.0, Active Control App
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- Evidence-Based Practice Institute, Seattle, WA
Suicide Prevention
Increasing Help-Seeking Behavior Among Transitioning Veterans at Risk for Suicide With Online Gatekeeper Training
The purpose of this study is to evaluate the feasibility and acceptability of a gatekeeper training called VA S.A.V.E. which was developed through a partnership between the VA and the PsychArmor Training Institute.
- Trial name
- NCT04565951
- Testing
- VA S.A.V.E.
- Where
- United States
- Volunteers
- 281 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Self-Harm, Deliberate, Suicide, Attempted
Brief Admission for Adolescents Who Self-harm
There is still no consensus on how to manage suicidal behavior in youth with recurrent self-harm at times when the risk for suicide is imminent (1).
- Conditions
- Self-Harm, Deliberate, Suicide, Attempted, Suicidal, Non-Suicidal Self Injury
- Trial name
- NCT04962373
- Testing
- Semi-structured interviews
- Where
- Sweden
- Volunteers
- 59 people
- Sponsor
- Region Skane
Substance-related Disorders, Depression
Primary Care iSBIRT to Reduce Serious Teen Health Risks
The goal of the project is to develop and test an internet/intranet-based Screening, Brief Intervention, and Referral to Treatment (iSBIRT) system for adolescents that targets a broad range of serious health-risks and problem…
- Conditions
- Substance-related Disorders, Depression, High-risk Sex
- Trial name
- NCT00891631
- Testing
- iSBIRT, iSBIRT/TE
- Where
- United States
- Sponsor
- Boston Children's Hospital
Suicide
Suicide Risk Interventions
The suicide rate among active duty service members and Veterans increased substantially following the onset of post-9/11 conflicts in Iraq and Afghanistan.
- Trial name
- NCT05931289
- Testing
- Enhanced Crisis Response Planning (ECRP), Brief Cognitive Behavioral Therapy for Suicide Prevention (BCBT)
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- VA Office of Research and Development
Suicide Risk, Major Depressive Disorder (MDD)
Orexin Antagonism for Suicide Risk: A Proof-of-Concept Clinical Trial
The goal of this proof-of-concept clinical trial is to evaluate the initial safety, feasibility, and tolerability of the orexin mixed antagonist suvorexant in a sample of veteran adults with Major Depressive Disorder and elevated…
- Trial name
- NCT06854224
- Testing
- Suvorexant (dual orexin receptor antagonist)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Marianne Goodman
Major Depressive Disorder
Long-Term Maintenance With Ketamine and Esketamine for Reduction of Suicide in High-Risk Patients With Depression
The study will consist of a 24-week-long trial examining outcomes in patients with Major Depressive Disorder and suicidal ideation who will receive intravenous (IV) ketamine and intranasal (IN) esketamine, compared to a large…
- Trial name
- NCT05450432
- Testing
- Ketamine, Esketamine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Suicide, Attempted
Inpatient Cognitive-Behavioral Therapy to Reduce Suicide Risk Post-Discharge
The goal of this randomized-controlled trial is to determine whether adding brief cognitive-behavioral therapy for suicide prevention (BCBT) to inpatient treatment improves suicide-related outcomes after the person leaves the…
- Trial name
- NCT04168645
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- Hartford Hospital
Reintegration Difficulties, Suicidal Ideation and Behaviors
Expanding Veteran Sponsorship Initiative+ to Support High-Risk Transitioning Servicemembers and Veterans: A Precision Medicine Approach
Background Young Veterans in the U.S. face a heightened risk of suicide, particularly during the first year after leaving military service-a period often referred to as the "deadly gap." Suicide rates among Veterans aged 18 to 34…
- Conditions
- Reintegration Difficulties, Suicidal Ideation and Behaviors, Health, Connectedness
- Trial name
- NCT07356492
- Testing
- Onward Ops- receive peer sponsor and community support, VA stepped care services
- Where
- United States
- Volunteers
- 2,700 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Suicidal Ideation, Suicide Attempt
Efficacy, Effectiveness, and Implementation of Jaspr Health in Emergency Department- Part A
This Study will comprehensively evaluate a multi-component suicide prevention technology (Jaspr Health) that facilitates delivery of suicided-related evidence-based practices (EBPs) while replacing wasted waiting time with…
- Conditions
- Suicidal Ideation, Suicide Attempt, Self Harm
- Trial name
- Jaspr-PartA (NCT06223867)
- Testing
- Jaspr App + JAH, ETAU
- Where
- United States
- Volunteers
- 670 people
- Sponsor
- University of Massachusetts, Worcester
Suicide, Suicide Prevention
Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial
Pragmatic randomized controlled trial to compare the effectiveness of two-way Caring Contacts text messages vs. one-way Caring Contacts text messages vs. enhanced usual care for suicide prevention in adults and adolescents.
- Conditions
- Suicide, Suicide Prevention, Suicide and Self-harm
- Trial name
- SPRING (NCT06128239)
- Testing
- Caring Contacts
- Where
- United States
- Volunteers
- 854 people
- Sponsor
- St. Luke's Health System, Boise, Idaho
Suicidal Ideas, Suicidal Ideation
Couple-Based Crisis Safety Planning
Suicide is a leading cause of death in Veterans. Suicide rates among Veterans have increased approximately 36% from 2001 to 2020.
- Conditions
- Suicidal Ideas, Suicidal Ideation, Crisis; Emotional, Suicide Attempts
- Trial name
- CRP-C (NCT07012824)
- Testing
- Crisis Response Planning, Couples-based Crisis Response Planning
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Georgia
Suicide
Gun Locks in Firearm Suicide Intervention
This study compares the effectiveness of two interventions for suicide over the course of a month. The experimental intervention includes the provision of a gun lock with video instructions, in addition to standard suicide risk…
- Trial name
- NCT03835585
- Testing
- Gun lock, Suicide Risk Assessment, Safety Planning
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Florida State University
Mechanistic Self-Dehumanization Condition, Control Condition
Inducing Self-Dehumanization to Examine Oxytocin and Suicide Risk
The goal of this experiment is to further determine if self-dehumanization is a novel risk factor for suicide. This study will induce self-dehumanization using a novel experimental self-dehumanized future condition (i.e., a…
- Trial name
- NCT06710964
- Testing
- The Ten Item Personality Inventory, Mechanistic Self-Dehumanization Condition, Debrief
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florida State University