Clinical trials: Suicide, Attempted, open to volunteers
PTSD, Suicidal Ideation
Enhancing the Effectiveness of Prolonged Exposure Among Suicidal Individuals With PTSD
The long-term goal of this study is to reduce suicidal thoughts and behaviors among treatment-seeking individuals who also have posttraumatic stress disorder (PTSD).
- Conditions
- PTSD, Suicidal Ideation, Suicide, Attempted, Trauma, Psychological
- Trial name
- NCT06285708
- Testing
- Prolonged exposure
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Ohio State University
Depression, Suicide
Youth Depression and Suicide Research Network
The objective of this study is to build the Texas Youth Depression and Suicide Research Network to support the development of a Network Participant Registry and characterization of systems and interventions to examine statewide…
- Conditions
- Depression, Suicide, Suicidal Ideation, Suicide, Attempted
- Trial name
- YDSRN (NCT04572321)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- University of Texas Southwestern Medical Center
Inhibitory Control, Locus of Control
Neuropsychological Patterns of Suicide Ideators and Suicide Attempters
The present study consists of 3 projects in total and aims to investigate the (neuro-) psychological patterns from suicidal ideation to suicidal behavior as well as the effects and feasibility of ASSIP Home Treatment.
- Conditions
- Inhibitory Control, Locus of Control, Self Efficacy, Suicide, Attempted
- Trial name
- NePsyAssip HT (NCT06248268)
- Testing
- (Neuro-)psychological assessment
- Where
- Switzerland
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Bern
Suicide, Attempted, Functioning, Psychosocial
iFD-SuRvivE funCtiONal effiCacy and bIologicaL corrElates (RECONCILE Study)
The goal of this clinical trial is to assess the effectiveness of an original intervention 'Functional Recovery in Depression and Suicide Risk Prevention Based on Emotion Regulation and Values: A Group Program' (from the original…
- Conditions
- Suicide, Attempted, Functioning, Psychosocial, Cognition, Neuroimaging
- Trial name
- RECONCILE (NCT05655390)
- Testing
- 'Functional Recovery in Depression and Suicide Risk Prevention Based on Emotion Regulation and Values: A Group Program'
- Where
- 4 sites in Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Iria Grande
Suicide Attempt
Preventing Suicide With Digital Phenotyping and Pharmacogenetics-Based Interventions
The goal of this protocol for an observational retrospective multi-site cohort study is to develop a predictive algorithm for suicidal behavior integrating genetic risk markers, digital phenotypes, and exposomic data in people…
- Trial name
- SMARTomicS-R (NCT07422090)
- Testing
- No Intervention: Observational Cohort
- Where
- Spain
- Volunteers
- 5,000 people
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Suicide, Attempted
A Randomized Clinical Study of "Attempted Suicide Short Intervention Program" in Swedish Healthcare - ASSIP
This is a randomized study of ASSIP as a treatment for patients who have recently made a suicide attempt. Six psychiatric clinics from four regions in Sweden are included. Together 460 patients will be recruited.
- Trial name
- NCT04746261
- Testing
- ASSIP + treatment as usual, Treatment as usual and patient safety
- Where
- 2 sites in Sweden
- Volunteers
- 460 people
- Sponsor
- Region Skane
Suicide, Attempted, Suicide Ideation
Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings
This multisite randomized controlled trial will compare two brief interventions for youth and young adults ages 12-24 following an acute care visit for suicide risk: the Stanley-Brown Safety Planning Intervention with follow-up…
- Conditions
- Suicide, Attempted, Suicide Ideation, Suicide, Suicide Prevention
- Trial name
- Project HOPE (NCT06151158)
- Testing
- Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI)
- Where
- 6 sites in United States
- Volunteers
- 484 people
- Sponsor
- Johns Hopkins University
Suicide Prevention
Suicide Prevention After Community Care Discharge
The study is of high importance to Veterans' health because it will study a suicide prevention intervention in a Veteran population that is at high risk of suicide but has not been a specific focus of the Veteran Affairs' (VA's)…
- Trial name
- NCT06596044
- Testing
- VA BIC, Standard Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- VA Office of Research and Development
Suicide
THRIVE: A Recovery-Focused Suicide Prevention Intervention in Crisis Stabilization Centers
Suicide is a major public health concern in the United States, with more than 1.4 million adults attempting suicide and nearly 50,000 adults dying by suicide each year.
- Trial name
- THRIVE (NCT07784634)
- Testing
- Toward Hope, Recovery, Interpersonal Growth, Values, and Engagement (THRIVE), Center Care as Usual
- Where
- 3 sites in United States
- Volunteers
- 552 people
- Sponsor
- University of Alabama at Birmingham
Suicide, Suicide Attempt
Nudging Parental Actions for Youth Suicide Prevention
The goal of the study is to determine effectiveness of a behaviorally informed text messaging intervention to help parents increase safety practices and reduce their teens' access to lethal means following a suicide-related…
- Trial name
- NCT07383714
- Testing
- Text-messaging for safety reminders, Text-messaging with safety reminders and risk framing
- Where
- United States
- Volunteers
- 129 people
- Sponsor
- University of Texas Southwestern Medical Center
Violent Suicide Attempts in Adolescents
Mentalization and Social Cognition in Adolescents After Suicide Attempt
This study investigates the risk of violent suicide attempts in adolescents, with a particular focus on social cognition and sleep disturbances, to better understand the cognitive and behavioral mechanisms involved and to inform…
- Trial name
- MENTACOG-TS (NCT07688798)
- Testing
- Test, Questionnaires
- Where
- France
- Volunteers
- 82 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Major Depressive Disorder, Suicidal Ideas
Neural-Derived Plasma Exosomal MicroRNAs As Promising Novel Biomarkers for Suicidality and Treatment Outcome in Adolescents
This study is dedicated to help identify biomarkers for depression and suicide. The purpose of the study is to better understand these links to improve medical and psychiatric care in the future.
- Conditions
- Major Depressive Disorder, Suicidal Ideas, Suicide, Attempted, MDD
- Trial name
- NCT05437588
- Testing
- Genetic testing
- Where
- 2 sites in United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Suicide, Suicide Attempt
Lock and Protect: Reducing Adolescent Access to Lethal Means of Suicide
The primary goal is to determine the acceptability and feasibility of implementing the Lock and Protect decision aid. The secondary goals are to identify the potential short-term impact of Lock and Protect on home firearm and…
- Conditions
- Suicide, Suicide Attempt, Adolescent Suicidality, Suicide Ideation
- Trial name
- NCT07111052
- Testing
- Lock and Protect is a self-administered, web-based decision aid for caregivers of adolescents at risk for suicide.
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Columbia University
Suicide Ideation, Suicide Attempt
Plan and Protect: Safety Planning for Teens in Rural Emergency Departments
The goal of this observational study is to determine whether implementing a culturally sensitive, tablet-based safety planning program called Plan \& Protect (P\&P) within rural emergency departments can improve home safety and…
- Trial name
- NCT07325474
- Testing
- Plan & Protect safety planning intervention, Care as usual
- Where
- 6 sites in United States
- Volunteers
- 550 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Suicidal Ideation, Suicide Attempt
Neural Correlates of Suicidal Behavior in Youth
This study, titled "Neural Correlates of Suicidal Behavior in Youth: a Pre and Post CAMS Therapy Neuroimaging Study," aims to better understand the brain mechanisms underlying suicidal thoughts and behaviors in adolescents and…
- Conditions
- Suicidal Ideation, Suicide Attempt, Suicidal Behavior, Depression / Major Depressive Disorder
- Trial name
- NCT07568054
- Testing
- CAMS
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Major Depressive Episode (MDE), Major Depressive Disorder (MDD)
LHC-CIDI-5 in Hong Kong
The World Health Organization Composite International Diagnostic Interview-5th (CIDI-5) is a standardized diagnostic tool used to assess the prevalence of mental and substance use disorders over varying time frames (30 days, 12…
- Conditions
- Major Depressive Episode (MDE), Major Depressive Disorder (MDD), Persistent Depressive Disorder (PDD), Suicidal Ideation
- Trial name
- NCT06804525
- Testing
- CIDI-5, LHC-CIDI-5
- Where
- Hong Kong
- Volunteers
- 2,500 people
- Sponsor
- The University of Hong Kong
Suicide, Suicide Prevention
Caring Connections Youth Suicide Detection and Intervention Study
The goal of this pilot randomized control trial (RCT) is to test the feasibility of Caring Connections, a Culturally Adapted Linking Individuals Needing Care (CA-LINC) suicide prevention care coordination intervention for…
- Conditions
- Suicide, Suicide Prevention, Suicide Ideation, Suicide Attempt
- Trial name
- CA-LINC (NCT06353711)
- Testing
- Caring Connections, Treatment as Usual
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of North Carolina, Chapel Hill
Suicidal Ideation, Suicide Attempt
A Randomized Controlled Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior
This study aims to evaluate the acceptability, safety, and efficacy of a smartphone-delivered intervention called Therapeutic Evaluative Conditioning for Suicide (TEC-S) in reducing suicidal thoughts and behaviors (STB) among…
- Trial name
- NCT06686901
- Testing
- Smartphone-delivered Therapeutic Evaluative Conditioning for Suicide (TEC-S), Smartphone-delivered inactive Therapeutic Evaluative Conditioning
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Suicide Ideation, Suicide Attempts
Brief Cognitive Behavioral Therapy for Suicide Prevention in a Brazilian Sample: a Study Protocol of a Randomized Clinical Trial
The vast majority of suicides occur in low-and middle-income countries (LMICs), and evidence on effective psychotherapeutic interventions to prevent suicide that are culturally adapted to these contexts is limited.
- Trial name
- NCT07574658
- Testing
- Brief Cognitive-Behavioral Therapy (BCBT) for Suicide Prevention, Supportive Therapy
- Volunteers
- 150 people
- Sponsor
- University of Sao Paulo
Suicidal Ideation, Self-Injurious Behavior
Youth Suicide and Self-Harm Intervention: Clinical and Biological Outcomes Study
The goal of this clinical trial is to develop and evaluate youth-focused intervention programs for suicide and self-harm that are tailored to the psychological, developmental, and cultural characteristics of Korean adolescents…
- Conditions
- Suicidal Ideation, Self-Injurious Behavior, Suicide, Attempted
- Trial name
- SHIELD (NCT07395752)
- Testing
- Self-Harm Intervention and Education for Long-term Development (SHIELD) Program, General Mental Health Education
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Ajou University School of Medicine