Clinical trials: Sugar Intake
Fat; Liver, NAFLD
The Effect of a High-fat vs. High-sugar Diet on Liver Fat Accumulation and Metabolism
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent liver disease in the world. It is currently unclear why fat starts to accumulate in the liver, although both the amount and type of food consumed have been…
- Trial name
- NCT03145350
- Testing
- High-fat, low-carbohydrate, Low-fat, high-carbohydrate
- Where
- United Kingdom
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Healthy Diet, Healthy Aging
Acute Effects of Added Sugar Intake on Cerebrovascular Function and Brain Integrity
This study will focus on acute effects of added sugars on brain health in a specific age group (30-64 years old). We will provide participants two meals (one meal containing 16 g of added sugars and the other containing 61 g of…
- Trial name
- NCT05408338
- Testing
- Low Added Sugar Meal, High Added Sugar Meal
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Diabetes Prevention
Diabetes Prevention Program Pilot Study
This pilot study is intended to demonstrate that we can actually deliver the Diabetes Prevention Program intervention well and to show that it is likely effective.
- Trial name
- DPP (NCT00729079)
- Testing
- DPP
- Where
- 2 sites in United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Nutritional Deficiency
Effects of Metabolic Testing Data and Education on Attitudes and Beliefs Related to Carbohydrate Intake in Adolescent Female Athletes
Many studies have consistently shown that females across sports under consume carbohydrate. Registered dietitians working with athletes have also reported female athletes chronically under consume carbohydrate.
- Trial name
- NCT06837376
- Testing
- Education, Metabolic Testing (Exercise) with shared interpreted results
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Dyslipidemia, Obesity, Abdominal
Effects of Almond Intake on Atherogenic Lipoprotein Particles
Increased abdominal adiposity is a key feature of metabolic syndrome, which describes a cluster of cardiovascular disease (CVD) risk factors that also includes insulin resistance, high blood pressure and an atherogenic…
- Trial name
- NCT01792648
- Testing
- Standard reference diet, Almond supplemented diet, Low carbohydrate reference diet
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- UCSF Benioff Children's Hospital Oakland
Healthy
Food Matrices Based on Fruit Pastes as Vectors of Carbohydrates for the Prevention and Management of Protein-energy Undernutrition in the Elderly (Fruisenior)
To develop more natural fruit pastes matrices that can effectively act as carbohydrate vectors in the elderly population and that are part of a normal diet while maintaining the pleasure of eating.
- Trial name
- Fruisenior (NCT04482530)
- Testing
- fruit paste matrice
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Childhood Obesity
Sugars-containing Beverage and Food Intake in Children
The purpose is to determine the effect of sugars in solution on food intake and subjective appetite in 9- to 14-year-old normal weight boys.
- Trial name
- NCT01717716
- Testing
- water with Sucralose, water with HFCS, water with glucose
- Where
- Canada
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Toronto Metropolitan University
Metabolic Health
Changes in Sugar-sweetened Beverage Intake and Metabolic Health: Improving Metabolic Profile Very Effortlessly
Sugar-sweetened beverages (SSBs) have been epidemiologically linked to serious health problems including heart disease, liver disease, and diabetes.
- Trial name
- IMPROVE (NCT02585336)
- Testing
- Brief intervention
- Where
- United States
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Validation Studies
d13C Added Sugar Intake Biomarker: Determining Validity in Children
Added sugars (AS) constitute a significant source (~ 16%) of the total daily calories consumed by youth. The role of AS in health is contentious, and the reliance on self-reported dietary data is an often-cited flaw in existing…
- Trial name
- NCT02455388
- Testing
- High added sugar diet, Low added sugar diet
- Where
- United States
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Virginia Polytechnic Institute and State University
Obesity, Diabetes
The Effects of Carbohydrate Source on Food Intake, Blood Glucose and Gut Hormone Response in Healthy Children
This study will compare the effects of commonly consumed carbohydrate sources such as potatoes, pasta and rice along with a fixed portion of meat on blood glucose, satiety and insulin levels among healthy body weight children.
- Trial name
- NCT02499107
- Testing
- Rice treatment, Pasta treatment, Boiled and mashed potato treatment
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Lactose Intolerance
Effect of B.Bifidum 900791 Intake in Adult With Hypolactasia and Lactose Intolerance
Lactase is high in the newborn intestine, allowing him to digest the high amounts of lactose present in breastmilk. From weaning, lactase is genetically programmed to decrease, reaching residual levels in the adult.
- Trial name
- NCT03952988
- Testing
- Probiotic ice cream
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chile
Obesity Prevention, Diabetes Prevention
Types of Starch and Their Effect on Blood Glucose, Appetite and Food Intake
The investigators hypothesize that different types of starch vary in their effects on appetite, blood sugar and food intake. In this study, subjects consumed five soups containing 50 g of whole grain, high amylose corn, regular…
- Trial name
- NCT00980941
- Testing
- soup with or without starch
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Obesity
Carbohydrate Intake and Gut Hormone Release During Exercise
It is well known that following a single session of moderate-to-high intensity exercise individuals experience a temporary suppression of hunger and a delay in the commencement of eating.
- Trial name
- NCT04019418
- Testing
- Maltodextrin (carbohydrate), Exercise, Rest
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Dietary Recommendations
Dietary Recommendations for Reducing Free Sugar Intakes
This randomised controlled trial aims to assess the impacts of the current recommendations by Public Health England for reducing free sugar intakes, on total energy intakes of free sugar in a sample of the UK population.
- Trial name
- NCT04816955
- Testing
- Dietary recommendations
- Where
- United Kingdom
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Bournemouth University
Sports Performance, Sports Nutritional Sciences
Effect of Infusion of Yerba Mate on Oxidative Stress, Physiology, and Performance of Trained Cyclists
This project comes forward with investigations regarding the use of yerba mate infusion in sports performance, providing new knowledge about the effects of its consumption on the performance of trained individuals, thus…
- Conditions
- Sports Performance, Sports Nutritional Sciences, Endurance Performance
- Trial name
- NCT04642144
- Testing
- Yerba mate infusion, Carbohydrate meal
- Where
- Brazil
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Santa Catarina
Dehydration
Fluid Balance During Exercise in the Heat With Water, Flavored Placebo, or a Carbohydrate-electrolyte Beverage Intake (The APEX Study)
The purpose of the APEX study is to determine whether carbohydrate-electrolyte beverage intake promotes fluid balance during exercise in the heat compared with water or placebo intake.
- Trial name
- APEX (NCT01893853)
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Obesity
What is the Maximum Amount of Carbohydrates That is Still Able to Induce Ketosis and Suppress Appetite?
Two dietary approaches, very low energy diets (VLEDs) and ketogenic low carbohydrate diets (KLCDs), have the ability to suppress appetite.
- Trial name
- NCT02944253
- Testing
- Low energy diet 70 gram carbohydrates, Low energy diet 100 gram carbohydrates, Low energy diet 130 gram carbohydrates
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
High Whole Grain and Low Sugar, Medium Whole Grain and Low Sugar
Health Effects of Grain Foods in Adults
This study will assess the effects of eating whole grain foods versus refined grain foods with different amounts of added sugar.
- Conditions
- High Whole Grain and Low Sugar, Medium Whole Grain and Low Sugar, Low Whole Grain and Low Sugar, Low Whole Grain and High Sugar
- Trial name
- NCT06339879
- Testing
- High Whole Grain, Low Sugar, Low Whole Grain, Low Sugar, High Whole Grain, High Sugar
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Purdue University
Development, Child
Snacks, Smiles and Taste Preferences
The research study is designed is to determine whether children's acceptance of low sugar snacks, most preferred level of sweet and salty taste, and dietary intake of added sugars changes after repeated exposure to snacks lower…
- Trial name
- NCT03631992
- Testing
- Low Sweet, Regular Sweet
- Where
- 2 sites in United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Temple University
Choroid
Effects of Acute Sugar Intake on Choroidal Thickness
This study aims to bridge that gap by investigating how acute sugar intake influences choroidal thickness.
- Trial name
- NCT07376005
- Testing
- Oral glucose
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry