Clinical trials: Subthreshold Depression
Depression
Collaborative Stepped-care Intervention for Adults With Subthreshold Depressive Symptoms in the Primary Care Setting
To ensure accessibility and availability of mental health services in the community and to reduce the burden associated with depression and related conditions, the study aim to evaluate the effectiveness of a collaborative…
- Trial name
- NCT06658041
- Testing
- Cognitive behavioural therapy (CBT)-based intervention with stepped-care, Care-as-usual
- Where
- Hong Kong
- Volunteers
- 352 people
- Sponsor
- The University of Hong Kong
Depression
Transcranial Magnetic Stimulation in Depression
The study examines efficacy of repetitive transcranial magnetic stimulation in treating severely depressed patients who are medicated.
- Trial name
- NCT00018746
- Testing
- repetitive transcranial magnetic stimulation
- Where
- United States
- Sponsor
- US Department of Veterans Affairs
Depression
Treatment of Mild and Subthreshold Depressive Disorders
The purpose of this study is to determine the efficacy of a SSRI, cognitive-bahavioral-therapy and a free choice between SSRI and CBT in a sample of primary care patients suffering from mild to moderate depression.
- Trial name
- NCT00226642
- Testing
- Sertralin, Cognitive-behavioral therapy, Non-specific supporting group therapy
- Where
- Germany
- Volunteers
- 369 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Subthreshold Depression, Depressive Symptoms
Evaluation of Efficacy of Lycium Barbarum Polysaccharide in People With Subthreshold Depression
Lycium barbarum, a traditional Chinese herbal medicine, is a commonly used herb in the traditional Chinese pharmacopoeia . Its main active ingredient, lycium barbarum polysaccharide (LBP), is reported to have neuroprotective…
- Conditions
- Subthreshold Depression, Depressive Symptoms, Anxious Symptoms
- Trial name
- NCT04032795
- Testing
- Lycium barbarum polysaccharide
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Guangzhou Psychiatric Hospital
Subthreshold Depression
tDCS in People With Subthreshold Depression
This study evaluates the effects of multi-session transcranial direct current stimulation on loneliness, mood and depressiveness in people with subthreshold depression.
- Trial name
- NCT06517121
- Testing
- Personalized Experimental Transcranial Direct Current Stimulation (tDCS), Conventional Experimental Transcranial Direct Current Stimulation (tDCS)
- Where
- Hong Kong
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Education University of Hong Kong
Subthreshold Depression, Exercise
The Effect of Exercise on Cognition and Preventing Depression in Young People
It is estimated that approximately 30% of child and adolescents manifest subthreshold depression (including other specified depressive disorder and unspecified depressive disorder), which can further develop into major depression…
- Conditions
- Subthreshold Depression, Exercise, Clinically-well, Cognitive Change
- Trial name
- NCT04816617
- Testing
- Aerobic exercise intervention, Psycho-education
- Where
- China
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Anxiety, Depressive Symptoms
Group Program vs Single-Session Depathologizing Intervention for Subthreshold Anxiety-Depression in Primary Care (Spain)
This study evaluated two psychological interventions for adults with mild to moderate subthreshold anxious-depressive symptoms in primary care in Spain.
- Conditions
- Anxiety, Depressive Symptoms, Anxiety Symptoms, Subthreshold Depression
- Trial name
- NCT07363915
- Testing
- PADAP transdiagnostic CBT-based group program, Active Single-Session Depathologizing Intervention (SSDI)
- Where
- Spain
- Volunteers
- 136 people
- Sponsor
- University of Alcala
Subthreshold Depression
Effects of Virtual Reality-Based Horticultural Intervention for Older Adults With Subthreshold Depression in Nursing Homes
Subthreshold depression represents a state of psychological sub-health between normal individuals and clinical depression. It constitutes a high-risk stage for developing clinical depression and a critical phase for alleviating…
- Trial name
- NCT07275034
- Testing
- Virtual Reality-Based Horticultural Intervention System, routine health management
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Subthreshold Depression
Study Protocol for a Smartphone Application-based Intervention for Subthreshold Depression
The investigators plan to conduct a randomized controlled trial to examine whether a Smartphone-based Intervention improves subthreshold depression symptoms compared to no intervention.
- Trial name
- NCT04136041
- Testing
- Smartphone Application
- Where
- Japan
- Volunteers
- 32 people
- Sponsor
- Kibi International University
Subthreshold Depression, Positive Emotions
The Effect of Transcranial Direct Current Stimulation (tDCS) in Improving Emotion Health
The goal of this clinical trial is to investigate how transcranial direct current stimulation (tDCS) affects emotion functions in young adults aged 18-35 from the local community, including both male and female participants.
- Conditions
- Subthreshold Depression, Positive Emotions, Negative Emotions, Anhedonia
- Trial name
- NCT07319143
- Testing
- Transcranial Direct Current Stimulation
- Where
- Hong Kong
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Mild Cognitive Impairment, Subthreshold Depression
A One-year Trajectory of Depression Status Changes in Older Adults With MCI and SD: a Longitudinal Cohort Study
The purpose of this study is to investigate the one-year trajectory of changes in depression status in older adults with mild cognitive impairment and subthreshold depression, and to explore relevant risk factors for predicting…
- Conditions
- Mild Cognitive Impairment, Subthreshold Depression, Older Adults
- Trial name
- NCT06308627
- Where
- China
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Subthreshold Depression
Emotion-Belief Intervention for Subthreshold Depression in College Students
This study was a randomized controlled trial examining the long-term efficacy of an emotion-belief intervention on depressive symptoms in college students with subthreshold depression.
- Trial name
- NCT07869810
- Testing
- Single-session emotion-belief intervention, Continuous emotion-belief intervention, Sport-belief control
- Where
- China
- Volunteers
- 86 people
- Sponsor
- Huazhong University of Science and Technology
Subthreshold Depression
Needle-embedding Therapy Alleviates Depressive Symptoms and Resets the Function of Executive Control System in Subthreshold Depression People
The main objective of this trial is to evaluate the effectiveness of treating subthreshold depression by needle-embedding therapy.
- Trial name
- NCT04319562
- Testing
- needle-embedding therapy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Long-term Physical Health Conditions, Subthreshold Depression
Online Peer Support in Long-term Conditions
Over 15 million people in England live with a long-term physical health condition. Low mood, loneliness and worry related to chronic illness are very common.
- Trial name
- NCT06222346
- Testing
- CommonGround, NHS Mental Health
- Where
- United Kingdom
- Volunteers
- 126 people
- Sponsor
- King's College London
Post-stroke Depression, Subthreshold Depression
Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors
The overall objective of the project is to determine the effectiveness of tele-delivered behavioral activation (BA) by trained lay counselors (Tele-BA-S) to prevent Post-stroke depression (PSD) in low-income, older stroke…
- Trial name
- LIVE-WEL (NCT06864715)
- Testing
- Tele-delivered Behavioral Activation by lay counselors after Stroke (Tele-BA-S), Treatment as Usual
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- The University of Texas Health Science Center, Houston
Irritable Bowel Syndrome With Subthreshold Depression
Lactobacillus-containing Cultured Milk Drink Alleviates Depression Score Among Adults With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is frequently associated with any form of psychiatric comorbidities including subthreshold or subclinical depression.
- Trial name
- NCT05266443
- Testing
- Lactobacillus containing cultured milk drink
- Where
- Malaysia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Subthreshold Depression
A Pilot Study to Examine the Efficacy of Internet-Delivered Skills Training in Affective and Interpersonal Regulation (i-STAIR) for Individuals With Adverse Childhood Experiences and Subsyndromal Depression
The present study aims to pilot internet-delivered Skills Training in Affective and Interpersonal Regulation (i-STAIR) as a transdiagnostic emotion dysregulation intervention to prevent progression to depression in individuals…
- Trial name
- NCT07118072
- Testing
- Internet-Delivered Skills Training in Affective and Interpersonal Regulation, Online general psychoeducation
- Where
- Singapore
- Volunteers
- 150 people
- Sponsor
- Institute of Mental Health, Singapore
Mild Cognitive Impairment, Subthreshold Depression
A Trial of Combined Subthreshold Depression in Older Adults With Mild Cognitive Impairment Participating in Art Games
The presence of subthreshold depression accelerates quality of life decline and cognitive impairment in older adults with mild cognitive impairment, increasing the rate of dementia conversion, while the continuous decline in…
- Trial name
- NCT06706739
- Testing
- Online art game intervention group
- Where
- China
- Volunteers
- 87 people
- Sponsor
- Fujian Medical University
Depressive Symptoms, Diabetes Mellitus
Evaluation of a Diabetes-specific Cognitive Behavioural Treatment for Subthreshold Depression
This work is supported by the "Kompetenznetz Diabetes mellitus (Competence Network for Diabetes mellitus)" funded by the Federal Ministry of Education and Research (FKZ 01GI0809).
- Trial name
- NCT01009138
- Testing
- Diabetes-Specific CBT (DS-CBT), Standard Diabetes Education
- Where
- Germany
- Volunteers
- 214 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Depressive Symptoms, Hypomania Nos Single Episode or Unspecified
A Study of Aerobic Exercise for Adolescents With Subthreshold Mood Syndromes
This study will investigate the effects of aerobic exercise on mental states, cognition, and long-term outcomes in adolescents with subthreshold depressive and/or hypomanic syndromes and in non-clinical school children
- Trial name
- NCT03300778
- Testing
- aerobic exercise
- Where
- China
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital