Clinical trials: Substance Abuse Problem
Disease, Mental Disorders, Severe
Multifamily Group Psychoeducation for SUD's in Turkey
The aim of this study is to investigate the effects of multi-family group psychoeducation (MFGP) on the families of people living with a diagnosis of substance abuse disorder on patients and their families.
- Conditions
- Disease, Mental Disorders, Severe, Substance-Related Disorders, Substance Use Disorders
- Trial name
- NCT05564559
- Testing
- multifamily group psychoeducation
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Ege University
Substance Abuse
Strengthening Families Program Online
This Phase II SBIR tests a newly developed web-based online parenting skills training and youth drug prevention program based on the evidenced-based "Strengthening Families Program." The study design involves a three-condition…
- Trial name
- SFPonline (NCT04214327)
- Testing
- Strengthening Families Program Online eLearning Game, SFP Home-use DVD, Wait-Listed Control
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Strengthening Families Program LLC
Schizophrenia, Substance Abuse
Screening Protocol for Research Participants
The Screening Protocol is a system devised to evaluate potential research participants for National Institute on Drug Abuse/Maryland Psychiatric Research Center (NIDA/MPRC) studies.
- Conditions
- Schizophrenia, Substance Abuse, Cocaine Abuse, Tobacco Use Disorder
- Trial name
- ScreenProt (NCT01010620)
- Testing
- Various Screening psychiatric and medical assessments
- Where
- United States
- Volunteers
- 523 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse)
Youth to Text or Telehealth for Engagement in HIV Care
Youth To Text or Telehealth for Engagement in HIV Care (Y2TEC) is a randomized control pilot to assess the feasibility and acceptability of delivering a targeted problem-solving intervention to youth ages 18-29 living with HIV…
- Conditions
- HIV/AIDS, Mental Health Issue (E.G., Depression, Psychosis, Personality Disorder, Substance Abuse), Depression, Substance Use
- Trial name
- Y2TEC (NCT03681145)
- Testing
- Counselor delivered telehealth intervention
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Alcohol Drinking, Marijuana Smoking
Motivation and Skills for Delta-9-tetrahydrocannabinol/Ethanol (THC/ETOH+) Teens in Jail
This study will focus on treating substance abusing incarcerated teens using individually administered Motivational Interviewing (MI) followed by group Cognitive Behavior Therapy (CBT).
- Trial name
- SMART (NCT00506753)
- Testing
- MI/CBT, RT/SU
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Rhode Island
Adolescent, Depression
Sequenced vs. Integrated Delivery of Treatment for Adolescent Depression and SUD
The purpose of this study is to determine whether it is more effective to treat adolescents, with diagnoses of both depression and substance use disorder, with a treatment addressing the substance use first and then treating the…
- Conditions
- Adolescent, Depression, Substance Use Disorders
- Trial name
- Sequencing (NCT00680966)
- Testing
- Adolescent Coping With Depression/Functional Family Therapy
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Oregon Research Institute
Alcohol Abuse, Substance Abuse
Project BrEAtHe: A Culturally Tailored MBSR Intervention for Young Adult Black Men
The purpose of this study is to create a program focused on mindfulness and stress reduction specifically tailored to young adult Black males.
- Conditions
- Alcohol Abuse, Substance Abuse, Post Traumatic Stress Disorder
- Trial name
- BrEAtHe (NCT07009977)
- Testing
- self-guided mHealth app only, self-guided mHealth app + 'real-time' feedback
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- UConn Health
Cocaine Dependence
Oxytocin in Cocaine Dependence
Stress is likely involved in relapse to cocaine use. This project will investigate the role oxytocin may play in the stress response in cocaine-dependent men and women and examine how oxytocin may impact brain activity in…
- Trial name
- NCT01573273
- Testing
- Oxytocin, Saline
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- Medical University of South Carolina
Diabetes Mellitus, Chronic Kidney Diseases
The Multi-Ethnic Lifestyle Study
The study design is cross-sectional using a self-completion questionnaire in an English speaking multi-ethic population within Leicester and Leicestershire.
- Conditions
- Diabetes Mellitus, Chronic Kidney Diseases, Cardiovascular Diseases, Obstructive Sleep Apnea
- Trial name
- MELS (NCT04256720)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 9,500 people, healthy volunteers welcome
- Sponsor
- University of Leicester
HIV Infection, Substance Abuse
A Self-Assessment Intervention for Young Adult Polydrug Users at Risk for HIV
The proposed study is a three-armed randomized clinical trial. A total of 750 clients will be randomly assigned (using a random number table) to the interviewer-administered intervention, the self-administered intervention, and…
- Trial name
- NCT01362634
- Testing
- Trans-theoretical Process of Change Model-self, Trans-theoretical Process of Change Model - interviewer
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Nova Southeastern University
Overdose, Opioid-related Disorders
Phone Interview to Prevent Recurring Opioid Overdoses
There has been a dramatic rise in opioid overdose (OOD) deaths in recent years. Attempts to ameliorate the problem have largely focused on increasing the accessibility of naloxone, an opioid antagonist that is effective in OOD…
- Conditions
- Overdose, Opioid-related Disorders, Drug Addiction, Drug Abuse
- Trial name
- TTIP-PRO (NCT02282306)
- Testing
- TTIP-PRO
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Cincinnati
Opioid-use Disorder, Substance Use Disorders
Exablate for LIFU Neuromodulation in Patients With Opioid Use Disorder (OUD) and/or Other Substance Use Disorders (SUDs)
The purpose of this clinical trial is to investigate Low Intensity Focused Ultrasound (LIFU) using the Exablate® Model 4000 Type 2.0/2.1 as an adjunctive neuromodulatory treatment for OUD (Opioid Use Disorder) and/or other…
- Trial name
- NCT04197921
- Testing
- Exablate Model 4000 Type 2.0/2.1
- Where
- 4 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- InSightec
Substance Abuse, Stress, Psychological
Drug Abuse During the COVID-19 Pandemic.
The pandemic we live through has put various sectors of the medical system and its tributaries to the test. The accumulation of external and internal stress has been completely correlated with the predisposition to…
- Trial name
- NCT04811352
- Where
- Mexico
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Substance Use Disorders
Effectiveness of a Brief Cognitive and Behavioral Skills Program on Stage Transitions for Chronic Ketamine Abusers
In recent years ketamine abuse becomes prevalent in youth in some Asian countries. Chronic ketamine abuse may lead to uropathology and cognitive impairments.
- Trial name
- NCT03644719
- Testing
- Cognitive behavioral skills training
- Volunteers
- 409 people, healthy volunteers welcome
- Sponsor
- National Taiwan University
Opioid-Related Disorders, Drug Addiction
Medication Treatment for Opioid Use Disorder in Expectant Mothers
The primary objective of this study is to evaluate the impact of treating opioid use disorder (OUD) in pregnant women with extended-release buprenorphine (BUP-XR), compared to sublingual buprenorphine (BUP-SL), on mother and…
- Conditions
- Opioid-Related Disorders, Drug Addiction, Pregnancy Related, Substance Abuse
- Trial name
- MOMs (NCT03918850)
- Testing
- Buprenorphine Injection, Buprenorphine Sublingual Product
- Where
- 12 sites in United States
- Volunteers
- 140 people
- Sponsor
- T. John Winhusen, PhD
Substance Use Disorders
Home-based Continuing Care for Young Adults Leaving Residential Substance Abuse Treatment
The purpose of this project is to develop and test a Home-based Continuing Care intervention that will help parents support the recovery of their Young Adult (YA) child who is leaving residential substance abuse treatment.
- Trial name
- HCC (NCT02152033)
- Testing
- Home-based Continuing Care, Services as Usual
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Treatment Research Institute
Substance Abuse
Evaluation of Web-Based Recovery Monitoring With Clinical Alerts
The specific aims of the project are to conduct a three-phase study to develop a data-driven Clinical Alert feature to the RecoveryTrack™ Concurrent Recovery Monitoring (CRM) system and test its efficacy, as follows: Phase I …
- Trial name
- NCT01465555
- Testing
- Cognitive Behavioral Intervention
- Where
- 4 sites in United States
- Volunteers
- 389 people
- Sponsor
- Treatment Research Institute
Addiction, Substance Abuse Drug Chronic
Stage III Community-based Efficacy Trial for Mothering From the Inside Out
This is a Stage III community-based randomized clinical efficacy trial testing Mothering from the Inside Out (MIO), the first evidence-based parenting intervention designed to be delivered by addiction counselors in addiction…
- Conditions
- Addiction, Substance Abuse Drug Chronic, Child Neglect, Child Neglect Emotional
- Trial name
- NCT02955199
- Testing
- Mothering From the Inside Out (MIO), Parent Education
- Where
- United States
- Volunteers
- 97 people
- Sponsor
- Yale University
Substance Use, Delinquency
Family-based and Adolescent Residential Drug Treatment
The fundamental objective of this study is to compare the effectiveness of an intensive in-home family-based treatment, Multidimensional Family Therapy, with a multifaceted residential treatment, Adolescent Residential Treatment…
- Trial name
- ART (NCT01737632)
- Testing
- Multidimensional Family Therapy (MDFT), Adolescent Residential Treatment
- Where
- 2 sites in United States
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Miami
Substance Abuse, Offenders
Effects of Manualized Treatment in a Seamless System
The specific aims of this project are: 1. To conduct a randomized block experiment to test the effectiveness of different models of the seamless supervision/treatment system and traditional criminal justice supervision on…
- Conditions
- Substance Abuse, Offenders, Criminal Thinking, HIV Risk Behaviors
- Trial name
- Man Tx (NCT01372033)
- Testing
- Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 251 people
- Sponsor
- George Mason University