Clinical trials: Sub-fertility
Metabolic Syndrome X, Infertility
Female Subfertility: a Metabolic and Vascular Profile
Introduction: Overall, 10 - 15% of couples seek specialist help once in their lives when a spontaneous pregnancy does not occur.
- Trial name
- NCT02136472
- Where
- Netherlands
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Ovarian Failure, Thyroid Diseases
Thyroid Function and Autoimmunity in Subfertility Women and Assisted Reproductive Therapy
The assessment of ovarian reserve is well established based on the dosage of anti-Mullerian hormone (AMH). The clinical applicability of detecting thyroid autoantibodies levels has been discussed as a potential marker of…
- Trial name
- NCT06394466
- Testing
- Non Applicable
- Where
- Brazil
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Subfertility
Hormonal Stimulation in IUI Treatment: Is Clomifen Combined With Ethinyl Estradiol Better, Worse or Equal to Menopur
What is the best medication for hormonal stimulation in cycles with high intra-uterine insemination: tablets of Clomifen (5 days) followed by tablets of Ethinyl Estradiol (5 days) or daily injections with Human Menopausal…
- Trial name
- NCT01569945
- Testing
- Clomifen, Ethinyl Estradiol, Menotropins
- Where
- Belgium
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Subfertility
BMI Effect on the Response to Ovulation Induction in Letrozole vs Clomid
There is an increased prevalence of high Body mass index (BMI) all over the world.High BMI is shown to have an impact on the female reproductive system.It can contribute to both ovulatory and anovulatory subfertility.
- Trial name
- NCT04331197
- Testing
- Clomiphene Citrate 50mg, Letrozole 2.5mg
- Volunteers
- 160 people
- Sponsor
- Cairo University
Male Subfertility
Role of Immunoglobulin in Male Infertility
to investigate the role of IVIG in male infertility and to determine its benefits in term of semen parameters and assisted reproduction outcome
- Trial name
- NCT06423989
- Testing
- IVIG
- Where
- Pakistan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Dr Salma kafeel Qureshi
Subfertility
Preimplantation Genetic Testing for Aneuploidy of Polar Bodies
This study intends to randomly group the patients with advanced maternal age and poor ovarian response, and the study group will undergo polar body biopsy, and the next-generation sequencing(NGS) technology will be used to…
- Trial name
- NCT04538560
- Testing
- polar body biopsy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Subfertility, Female
OCP Pretreatment in PCOS Patients Undergoing ICSI Using Antagonist Protocol
373 women with PCOS undergoing a trial of IVF/ICSI will receive OCP from day 2 of the preceding cycle for 21 days followed by GnRH antagonist COH.
- Trial name
- NCT03881904
- Testing
- 0.075mg gestodene/0.03mg ethinylestradiol
- Where
- Egypt
- Volunteers
- 740 people
- Sponsor
- Ain Shams University
Subfertility
Comparative Effect of Theipoental and Propofol in IVF Outcome
In this study the aim is to compare the effect of the type of anaesthetic drug used during oocyte retrieval on fertilization rates of oocytes retrieved after ovarian stimulation for in-vitro fertilization.
- Trial name
- NCT02377778
- Testing
- Propofol, Thiopental
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- Aristotle University Of Thessaloniki
Infertility, Reproductive Sterility
Post Market Surveillance & Post Market Clinical Follow up, International, Medical Registry to Confirm the Safety and the Performance of the Anecova Intra Uterine Culture Device
This study is designed to generate a comprehensive survey of the use on the market of the Anecova device within its intended indications according to the Instructions For Use.
- Trial name
- NCT03191890
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Anecova SA
Infertility, Female
Immediate Ambulation Versus Short-time Bed Rest in Sub-fertile Women Undergoing Embryo Transfer
Bed rest after embryo transfer (ET) has been clinically advised without robust scientific evidence. In investigators' unit, post ET instructions are given immediately after ET to sub-fertile women while lying in bed.
- Trial name
- NCT05148624
- Testing
- embryo transfer
- Where
- United Arab Emirates
- Volunteers
- 156 people
- Sponsor
- Dubai Fertility Center
Subfertility
Assessment of Intralipid Efficacy in Women With Unexplained Recurrent Implantation Failure
The study will include 100 women with unexplained recurrent implantation failure undergoing IVF/ICSI cycle. Patients fulfilling the inclusion criteria will be randomised into two groups.
- Trial name
- NCT02487940
- Testing
- Intralipid 20%, Normal saline
- Volunteers
- 100 people
- Sponsor
- Dar El Teb Institute
Male Infertility
Supplementation for Male Subfertility
Old age, obesity, physical inactivity, environmental factors and genetics may contribute negatively to fertility in both males and females.
- Trial name
- FertEnhancer (NCT06091969)
- Testing
- Active multi-ingredient supplement (Fertility Enhancer, FE)
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Subfertility
Oral Dydrogesterone as Luteal Phase Support in Natural Cycle FET
This randomised double-blinded controlled trial aims to compare the live birth rate in natural FET cycles with and without oral dydrogesterone as luteal phase support.
- Trial name
- NCT03859921
- Testing
- Dydrogesterone
- Where
- China
- Volunteers
- 716 people
- Sponsor
- The University of Hong Kong
Subfertility
Endometrial Scratching in Couples With Unexplained Subfertility
Endometrial scratching in luteal phase of a spontaneous menstrual cycle may increase pregnancy rate in women with unexplained infertility.
- Trial name
- ESUS (NCT01412606)
- Testing
- scratching
- Where
- Egypt
- Volunteers
- 105 people
- Sponsor
- Mansoura University
Subfertility
LH/HCG Receptor Expression and Retrieval Rates
The purpose of this study is to evaluate if there is an association between the serum LH receptor expression on the day of hCG administration or the day of oocyte retrieval and the retrieval rates at oocyte pick up
- Trial name
- NCT00438373
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Subfertility
GnRH Agonist for Dual Trigger in IVF and for Luteal Phase Support in FET
The objectives of this study are to compare the efficacy of the dual trigger group vs the hCG trigger group on the live birth rate in women undergoing IVF and the efficacy of the agonist in LP group vs the placebo group on the…
- Trial name
- NCT04064840
- Testing
- IVF: Decapeptyl and hCG, FET: Decapeptyl, IVF: hCG and normal saline
- Where
- China
- Volunteers
- 784 people
- Sponsor
- The University of Hong Kong
Subfertility
Day 3 Fresh Transfer Followed by Day 3 or Day 5 Vitrification of Supernumerary Embryos
This monocenter academic study aims to evaluate the effectiveness and cost effectiveness of two different strategies: fresh Embryo Transfer (ET) on day 3 followed by cryopreservation of cleavage-stage (Day 3) embryos versus…
- Trial name
- NCT04196036
- Testing
- Day of vitrification
- Where
- Belgium
- Volunteers
- 150 people
- Sponsor
- Sophie Debrock
Subfertility
Combined Dehydropeiandrosterone and Growth Hormone in Women With Expected Poor Ovarian Response Undergoing ICSI
Two hundred and thirty women with expected poor ovarian response undergoing IVF/ICSI will be randomly divided into 2 equal groups using computer generated random numbers.
- Trial name
- NCT02766764
- Testing
- DHEA, Growth hormone
- Where
- 2 sites in Egypt
- Volunteers
- 230 people
- Sponsor
- Cairo University
Periodontitis, Sub-fertility
Association Study Between Periodontal Disease and Male Infertility
The aim of the present study is to examine the association between fertility parameters and the periodontal status of men attending fertility and in vitro fertilization clinic.
- Trial name
- NCT01140945
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Subfertility
Clinical Effectiveness of Frozen Thawed Embryo Transfer Compared to Fresh Embryo Transfer
The objective of the present randomized controlled study is to compare clinical effectiveness and safety of freezing all embryos followed by frozen-thawed embryo transfer (FET) compared to fresh embryo transfer, in women…
- Trial name
- NCT02570386
- Testing
- Fresh embryo transfer, Frozen embryo transfer
- Where
- China
- Volunteers
- 138 people
- Sponsor
- The University of Hong Kong