Clinical trials: Strongyloides Stercoralis Infection
Strongyloides Stercoralis Infection, Device Performance
Evaluation of the Rapid Diagnostic Test SsRT+ for Strongyloides Stercoralis
The goal of this performance study is to determine if the diagnostic accuracy of the SsRT+ for the diagnosis of S. stercoralis infection meets the minimum requirements defined in the WHO target product profile.
- Conditions
- Strongyloides Stercoralis Infection, Device Performance, Diagnostic
- Trial name
- NCT07876622
- Testing
- Analysis of serum samples using two in vitro diagnostic devices (SsRT+ and Ss Rapid)
- Where
- Italy
- Volunteers
- 780 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Dengue, Chikungunya
Risk Assessment of Community Spread of Multiple Endemic Infectious Diseases in a One Health Perspective
RACSMEI addresses the high burden of infectious diseases in low- and middle-income countries, including Cambodia, where limited surveillance and laboratory capacity often obscure etiologies and transmission dynamics.
- Conditions
- Dengue, Chikungunya, Zika Virus Infection, Japanese Encephalitis
- Trial name
- RACSMEI (NCT07358910)
- Where
- Cambodia
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur du Cambodge
Strongyloides Stercoralis Infection, Strongyloides
Strongyloides Stercoralis Public Health Control in Rwanda
The World Health Organization (WHO) recently issued guideline for the public health control of Strongyloides stercoralis in endemic areas.
- Trial name
- SCAN (NCT07009613)
- Testing
- Parasitological tests, Questionnaire
- Where
- Rwanda
- Volunteers
- 1,415 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Strongyloides Stercoralis Infection
Efficacy, Safety, and PK of Ascending Dosages of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis
This study is a phase 2, blinded and randomized clinical trial. The phase 2a trial is single blinded and conducted in Lao, while the phase 2b trial is double-blinded and conducted in Lao and Cambodia.
- Trial name
- StrongMoxi (NCT04056325)
- Testing
- Moxidectin, Ivermectin
- Where
- Laos
- Volunteers
- 617 people
- Sponsor
- Jennifer Keiser
Strongyloides Stercoralis Infection, Strongyloidiasis
Efficacy and Safety of Emodepside in Adults Infected With Strongyloidiasis Stercoralis
Efficacy, safety and pharmacokinetics of ascending dosages of emodepside and in comparison to ivermectin against Strongyloidiasis stercoralis in adults: randomized stage II seamless adaptive controlled trials
- Trial name
- NCT06373835
- Testing
- Emodepside
- Where
- Laos
- Volunteers
- 202 people
- Sponsor
- Swiss Tropical & Public Health Institute
Strongyloides Stercoralis Infection
Preliminary Evaluation of Two Rapid Diagnostic Test Prototypes for Strongyloides Stercoralis Infection
Single center, no profit experimental study on sera available in the Tropica Biobank.
- Trial name
- PROTOSS (NCT06368609)
- Testing
- IgG RDT, IgG4 RDT
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Strongyloides Stercoralis Infection
The SsRI/NIE Recombinant Antigen ELISA for the Follow up of Patients Infected by Strongyloides Stercoralis
This is a single-center interventional study with an IVD medical device. The main objective of this study is to evaluate the ELISA SsIR/NIE test for the post-treatment follow-up of patients suffering from strongyloidosis, using…
- Trial name
- NCT06308705
- Testing
- InBios Strongy Detect TM IgG ELISA
- Where
- Italy
- Volunteers
- 38 people
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Strongyloides Stercoralis Infection
Efficacy and Safety of Moxidectin Versus Ivermectin Against Strongyloides Stercoralis
The study is an extension to the study StrongMoxi NCT04056325 and entails modifications based on the outcome of NCT04056325 part A. The study is a phase 3, double-blinded and randomized clinical trial conducted in Cambodia.
- Trial name
- StrongMoxi_KH (NCT04848688)
- Testing
- Moxidectin 2 mg, Ivermectin 3 mg
- Where
- Cambodia
- Volunteers
- 332 people
- Sponsor
- Jennifer Keiser
Strongyloides Stercoralis Infection, Strongyloidiasis
Treatment of Strongyloides Infection
The aim of this study is to evaluate the serologic response in patients with S. stercoralis infection after treatment with a regimen of two single doses of 200 µg/kg of ivermectin given 2 weeks apart versus a regimen of two…
- Trial name
- TSSI (NCT03605758)
- Testing
- Ivermectin
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Albert Einstein College of Medicine
Strongyloidiasis, Strongyloides Stercoralis Infection
Evaluation of Strongyloidiasis in Ecuador: a fieLd Laboratory Accuracy Study
the World Health Organization (WHO) has recently committed to promote the control of strongyloidiasis within 2030 targets for STH control programmes.
- Trial name
- ESTRELLA (NCT04999774)
- Testing
- Different diagnostic tests
- Where
- Ecuador
- Volunteers
- 781 people, healthy volunteers welcome
- Sponsor
- IRCCS Sacro Cuore Don Calabria di Negrar
Helminthiasis, Strongyloides Stercoralis Infection
Management of Soil-transmitted Helminthiasis and Strongyloidiasis
The general purpose of the project is to analyse soil-transmitted helminthiases (STH) in a highly endemic area in northern Argentina with a multidisciplinary approach.
- Trial name
- NCT01308268
- Testing
- Ivermectin + Albendazole
- Where
- Argentina
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Salta