Clinical trials: Stroke
Post-stroke Depression
ATtention Test and Executive Functions After STroke to Predict Depression.
The purpose of this study is to determine whether cognitive function evaluation (sustained attention, executive functions, working memory) during acute post-stroke is predictive of a 3 months post-stroke depression.
- Trial name
- ATTEST-Depress (NCT04008719)
- Testing
- Thymic history, Evaluation of the psychiatric disorders, Cognitive evaluation
- Where
- France
- Volunteers
- 74 people
- Sponsor
- Centre Hospitalier St Anne
Stroke, Acute
Imaging Collaterals in Acute Stroke (iCAS)
Stroke is caused by a sudden blockage of a blood vessel that delivers blood to the brain. Unblocking the blood vessel with a blood clot removal device restores blood flow and if done quickly may prevent the disability that can be…
- Trial name
- iCAS (NCT02225730)
- Where
- 4 sites in United States
- Volunteers
- 187 people
- Sponsor
- Stanford University
Covid19, Stroke, Acute
COVID-19 Stroke Apical Lung Examination Study
Multi-centre prospective study evaluating computed tomography angiography studies performed for stroke patients as a diagnostic and prognostic imaging biomarker.
- Conditions
- Covid19, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- NCT04640428
- Where
- 12 sites in United Kingdom
- Volunteers
- 2,000 people
- Sponsor
- King's College Hospital NHS Trust
Stroke, Psychosocial Problems
A Nurse-led Program for Stroke Patients
The aim of this study is to examine the effectiveness of nurse- led program on psychosocial problems and quality of life in stroke patients.
- Trial name
- NCT05242536
- Testing
- Nurse- led program
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Istanbul University - Cerrahpasa
Stroke
Remote Ischemic Conditioning for Acute Moderate Ischemic Stroke
The current treatment based on evidence-based medicine for acute ischemic stroke mainly includes reperfusion (intravenous thrombolysis, mechanical thrombolysis), anti-platelet and stroke units.
- Trial name
- RICAMIS (NCT03740971)
- Testing
- Remote Ischemic Conditioning treatment, Guideline-based therapy
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- General Hospital of Shenyang Military Region
Stroke
Multi-session Anodal Cerebellar Transcranial Direct Current Stimulation (tDCS) vs Anodal Cerebral tDCS
To investigate which one of the two cerebellar and cerebral stimulation in comparison to sham stimulation is more effective in enhancing balance and postural stability in stroke patients
- Trial name
- NCT06525129
- Testing
- Cerebellar stimulation group (CbSG), Cerebral (M1) Stimulation group (MSG)
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Caregiver Burden, Stroke
Evaluation of Musculoskeletal System in Caregivers of Rehabilitation Patients
In this study, musculoskeletal-related pain, posture, spine function, the condition of the low back and neck regions, musculoskeletal system disorders, fatigue, and quality of life will be examined in caregivers of rehabilitation…
- Conditions
- Caregiver Burden, Stroke, Cerebral Palsy, Neurologic Disorder
- Trial name
- NCT05839795
- Testing
- Assessment study
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Stroke
The Relationship Between Mood and Insomnia Severity and Caregiver Burden in Caregivers of Stroke
This study will include stroke patients aged 18-80 years and their caregivers. Demographic data such as age, height, weight, and comorbidities will be recorded, along with stroke-specific characteristics including duration of…
- Trial name
- NCT07253519
- Testing
- no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Traumatic Brain Injury, Acquired Brain Injury
Venous and Cerebral Glucose Microdialysis in Neurocritical Care: Validation & Correlation
This study evaluates the validity of an intravascular continuous glucose monitoring microdialysis probe, and compares the values to routinely inserted cerebral glucose microdialysis to evaluate the hypothesised relationship…
- Conditions
- Traumatic Brain Injury, Acquired Brain Injury, Intracerebral Hemorrhage, Subarachnoid Hemorrhage
- Trial name
- NCT03246607
- Testing
- MicroEye & ContinuMon
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Dr Andrew Stevens
Acute Stroke
The CLOQS Trial - Countdown Lights to Optimize Quality in Stroke
To reduce door-to-needle times in acute stroke treatment. Using an organizational behaviour intervention (a large stopwatch), we will post a visual cue to remind all parties that "time is brain".
- Trial name
- CLOQS (NCT01148602)
- Testing
- LED stopwatch-clock timers
- Where
- 3 sites in Canada
- Volunteers
- 3,452 people
- Sponsor
- Sunnybrook Health Sciences Centre
Hemianopia, Visual Field Defect Following Cerebrovascular Accident
Screening and Rehabilitation of Visual Field Defects in Post-Stroke Patients
In this study, the investigators will use a wearable device capable of performing this bedside assessment to evaluate the incidence of visual field loss in post-stroke patients.
- Trial name
- SCRiCaViPS (NCT07317739)
- Testing
- Early multisensory audio-visual stimulation training, Early visual field test
- Volunteers
- 300 people
- Sponsor
- Fondazione David Chiossone - Impresa Sociale
Stroke
Effects of PlayStation®VR on the HRQOL in Stroke Patients Undergoing Inpatient Rehabilitation
Compared to conventional rehabilitation therapy, the full-immersive commercial game (CG) system, in the form of available video game, could safely provide more positive effect on health-related quality of life (HRQOL) and motor…
- Trial name
- NCT04441177
- Testing
- PlayStation®VR training
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Chang Gung Memorial Hospital
Stroke Rehabilitation and Caregivers
Caregiver Burden in Stroke: Robot-Assisted Therapy vs Conventional Rehabilitation
Caregiver's burden in rehabilitation is important for both patients physical and mental health. Therefore researching caregivers burden and treatment of any depression or associated any psychological disorders of caregiver is…
- Trial name
- NCT03535467
- Testing
- Caregiver's Burden Inventory
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Post-stroke Spasticity, Spasticity Post-Traumatic Brain Injury
Dysport® Adult Lower Limb Spasticity Follow-on Study
The purpose of this research study is to assess the long term safety of Dysport® in hemiparetic subjects with lower limb spasticity due to stroke or traumatic brain injury over repeated treatment cycles.
- Trial name
- NCT01251367
- Testing
- Botulinum toxin type A
- Where
- 50 sites in United States, Australia and 9 more
- Volunteers
- 352 people
- Sponsor
- Ipsen
Stroke
Matão Preventing Stroke (MaPS): a Stroke Register Study
Stroke is one of the most important cause of mortality and disability in Brazil. The city of Matão, located in São Paulo state, with a population around 80.000 inhabitants, has conditions to develop a community-based stroke…
- Trial name
- MaPS (NCT03391102)
- Testing
- Observational study
- Where
- Brazil
- Volunteers
- 840 people
- Sponsor
- Centro Neurológico de Pesquisa e Reabiitação, Brazil
Ischemic Stroke
Albumin in Acute Ischemic Stroke Trial
The goal of the trial is to determine whether human albumin, administered within 5 hours of symptom onset, improves the 3-month outcome of subjects with acute ischemic stroke.
- Trial name
- ALIAS (NCT00235495)
- Testing
- Albumin, Saline
- Where
- 89 sites in United States, Canada and 2 more
- Volunteers
- 841 people
- Sponsor
- University of Miami
Atrial Fibrillation, T2DM (Type 2 Diabetes Mellitus)
RE-ELECT. Dabigatran vs Warfarin in AF Patients With T2DM and CKD
Kidney function in patients with atrial fibrillation (AF) is tending to decline over a time which is clearly demonstrated in clinical studies.
- Conditions
- Atrial Fibrillation, T2DM (Type 2 Diabetes Mellitus), Chronic Kidney Diseases
- Trial name
- RE-ELECT (NCT03789695)
- Testing
- Dabigatran Etexilate
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- Irina Ermolaeva
Acute Ischemic Stroke
A Safety and Dose Finding Study of Plasmin (Human) Administered Into the Middle Cerebral Artery of Stroke Patients
This study tests the drug, Plasmin (Human), in patients with a stroke due to a clot in the middle cerebral artery (MCA). Plasmin is an enzyme that causes clot lysis by cleaving a clot component, fibrin.
- Trial name
- NCT01014975
- Testing
- Plasmin (Human)
- Where
- 23 sites in Australia, Austria and 4 more
- Volunteers
- 40 people
- Sponsor
- Grifols Therapeutics LLC
D020521
fNIRS in the Evaluation of Cognitive-motor Interference in Post-stroke Patients
This study evaluates cognitive-motor interference in stroke patients who is responsible an alteration of spatio-temporal gait parameters.
- Trial name
- ICM-AVC (NCT03559283)
- Testing
- Walking and Record Cortical Activity
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Limoges
Stroke
Temporal Trends of Thrombolysis Treatment in Chinese Acute Ischemic Stroke (AIS) Patients From 2007-2017: Analysis of China National Stroke Registry (CNSR) I, II, and III; CTP-Draft Review Performed;
The present study is to be conducted based on the AIS patient data collected from CNSR I, II, and III. The primary objectives are: To investigate the temporal changes in the proportion of intravenous recombinant plasminogen…
- Trial name
- NCT04290494
- Testing
- IV rtPA (intravenous recombinant plasminogen activator)
- Where
- China
- Volunteers
- 42,188 people
- Sponsor
- Boehringer Ingelheim