Clinical trials: Stress Urinary Incontinence
Urinary Stress Incontinence
Safety and Efficacy Study on the Implantation of the Tension-Free Vaginal Tape (TVT-Secur) Under Local Anesthesia
The objective was to observe the satisfaction of local anesthesia during the implantation of the TVT-SECUR for the treatment of stress urinary incontinence, with the use of questionnaires completed by the patients, and to…
- Trial name
- NCT00904618
- Testing
- TVT-SECUR - 'Hammock' technique, TVT-SECUR - 'U-Method', Local anesthesia (30 to 40 ml of a mixture of 35 ml of lidocaine 2% and 5 ml of bicarbonate 3%).
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Université de Sherbrooke
Urinary Incontinence, Stress
Trans-obturator Mid-urethral Sling and the Single-incision Sling in Women With Stress Urinary Incontinence
Mid-urethral slings (MUS) now represent a gold standard in the treatment of female stress urinary incontinence (SUI). Second generation trans-obturator slings (TOT) have proven to be as effective as retropubic tension-free…
- Trial name
- NCT02506309
- Testing
- TOT - inside-out trans-obturator tape/sling, SIS - Innovative fixation single incision sling
- Volunteers
- 168 people
- Sponsor
- Brno University Hospital
Stress Urinary Incontinence
Autologous Cell Therapy for Female Stress Urinary Incontinence
The Autologous Cell Therapy for Female SUI study is a clinical trial to determine the safety and potential effectiveness of a single dose of 200 million Cook MyoSite Autologous Muscle Derived Cells for treatment of Stress Urinary…
- Trial name
- NCT01008943
- Testing
- Autologous Muscle Derived Cells
- Where
- 2 sites in Canada
- Volunteers
- 16 people
- Sponsor
- Cook MyoSite
Pelvic Organ Prolapse, Urinary Incontinence,Stress
Minimally Invasive Burch Colposuspension to Reduce Occult Stress Incontinence
This study evaluates the addition of a laparoscopic Burch colposuspension procedure at the time of laparoscopic sacrocolpopexy to prevent stress urinary incontinence.
- Conditions
- Pelvic Organ Prolapse, Urinary Incontinence,Stress, Urinary Incontinence, Urge, Bowel Dysfunction
- Trial name
- MICRO (NCT03841513)
- Testing
- Laparoscopic Burch Colposuspension
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Northwestern University
Urinary Incontinence, Stress, Intrinsic Sphincter Deficiency
AMS AdVance and AdVance XP Male Sling Systems for the Treatment of Stress Urinary Incontinence Following Prostatectomy: Evaluation of Safety, Efficacy, and Quality of Life Through Retrospective Chart Review and Prospective Follow-up
A single-center retrospective chart review of AdVance and AdVance XP subject data, combined with prospective follow-up of the same subjects to confirm continence, adverse event, and quality of life status.
- Trial name
- NCT01725984
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- American Medical Systems
Female Stress Incontinence
Continence Pessary Versus Disposable Intravaginal Device Trial
This is a multi-centered randomized controlled trial of women with stress urinary incontinence or stress predominant mixed urinary incontinence who desire non-surgical therapy.
- Trial name
- NCT03174431
- Testing
- Continence Pessary, Poise Impressa (Disposable Intravaginal Device)
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Ohio State University
Stress Urinary Incontinence
Bulking Agents for the Treatment of Stress Urinary Incontinence in Females
The primary purpose of this study is to demonstrate the safety and effectiveness of Bulkamid® in the treatment of stress urinary incontinence (SUI) due to intrinsic sphincter deficiency (ISD) in adult women who have SUI or stress…
- Trial name
- NCT00629083
- Testing
- Bulkamid, Contigen
- Where
- 34 sites in United States, Canada and 1 more
- Volunteers
- 345 people
- Sponsor
- Contura
Stress Urinary Incontinence
A Post-Market Study of the AMS AdVance™ Male Sling System for the Treatment of Male Stress Urinary Incontinence
A prospective, multi-center study of the AdVance Male Sling for Stress Urinary Incontinence. The purpose of this study is to obtain surgical technique data for use in physician education and training and to collect early clinical…
- Trial name
- NCT00998790
- Testing
- American Medical Systems (AMS) AdVance™ Male Sling System
- Where
- 3 sites in Belgium, France
- Volunteers
- 114 people
- Sponsor
- Boston Scientific Corporation
Stress Urinary Incontinence
Autologous Stem Cells for Urinary Incontinence: Single Patient Compassionate Use
Determine safety and effectiveness of the technique using autologous stem cells in the treatment of urinary incontinence in one male subject.
- Trial name
- NCT01648491
- Testing
- Muscle Biopsy, Injection of autologous stem cells
- Where
- 2 sites in United States
- Volunteers
- 1 people
- Sponsor
- Kenneth Peters, MD
Urinary Incontinence, Stress
A Pre-Market Study of the American Medical Systems (AMS) Transobturator Male Sling System for the Treatment of Male Stress Urinary Incontinence
The purpose of this study is to obtain surgical technique data for use in physician education and training and to collect early clinical outcomes data for future publication.
- Trial name
- AMS051 (NCT00904969)
- Testing
- The AMS Male Transobturator Sling System, AdVance Male Sling
- Where
- 11 sites in United States, Canada
- Volunteers
- 55 people
- Sponsor
- American Medical Systems
Stress Urinary Incontinence
A Randomized Controlled Trial of the Uresta Continence Pessary
Stress urinary incontinence (SUI) is defined as the involuntary loss of urine with an increase in abdominal pressure, caused either by a loss of support under the bladder neck, or intrinsic urethral sphincter deficiency.
- Trial name
- SURE (NCT01284244)
- Testing
- Uresta pessary, Silastic ring
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- Mount Sinai Hospital, Canada
Prolapse, Urinary Incontinence
Long-term Effectiveness of Abdominal Sacrocolpopexy for the Treatment of Pelvic Organ Prolapse
The Colpopexy and Urinary Reduction Effort (CARE) trial is a research study designed to evaluate whether the addition of a second surgical procedure in addition to a procedure for female pelvic organ prolapse (POP) affects the…
- Trial name
- E-CARE (NCT00099372)
- Where
- 8 sites in United States
- Volunteers
- 215 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Stress Urinary Incontinence
Preliminary Performance Study of the New TIPI Device in the Prevention of Stress Urinary Incontinence
Stress urinary incontinence (SUI) is most prevalent among women. SUI is characterized by loss of urine from increased abdominal pressures caused by coughing, laughing, sneezing, running, lifting or walking.
- Trial name
- NCT01770691
- Testing
- TIPI vaginal pessary
- Where
- Israel
- Volunteers
- 7 people
- Sponsor
- Assuta Hospital Systems
Urinary Incontinence, Stress, Urinary Incontinence, Urge
Group Learning Achieves Decreased Incidents of Lower Urinary Symptoms
This three-site randomized controlled trial compares the effectiveness and cost-effectiveness of a group-administered behavioral treatment program to no treatment.
- Trial name
- Gladiolus (NCT02001714)
- Testing
- Group Behavioral Treatment
- Where
- 4 sites in United States
- Volunteers
- 463 people
- Sponsor
- Ananias Diokno
Stress Urinary Incontinence
Pippa Pessary Study (Clinical Trial)
This is an open label, interventional, single arm, multi-clinic study where each adult female participant with stress urinary incontinence (SUI) serves as her own control (vaginal pessary use vs. no vaginal pessary).
- Trial name
- NCT05611970
- Testing
- Vaginal pessary
- Where
- 3 sites in United States
- Volunteers
- 7 people
- Sponsor
- Liv Labs Inc.
Stress Urinary Incontinence
Altis® 522 Trial - Treatment of Female Stress Urinary Incontinence
The aim of this postmarket study is to compare the safety and effectiveness of the Altis Single Incision Sling (SIS) to an FDA cleared transobturator and/or retropubic sling through 36 months.
- Trial name
- NCT02348112
- Testing
- Altis Single Incision Sling, Transobturator or Retropubic Sling
- Where
- 27 sites in United States, Canada
- Volunteers
- 416 people
- Sponsor
- Coloplast A/S
Pelvic Floor Disorders, Stress Urinary Incontinence
Educating Women About Pelvic Floor Disorders During Pregnancy
The purpose of this study is to assess the increase in knowledge of pregnant patients regarding pelvic floor disorders when comparing two educational interventions: written handouts vs interactive workshops.
- Conditions
- Pelvic Floor Disorders, Stress Urinary Incontinence, Pelvic Organ Prolapse
- Trial name
- NCT05440539
- Testing
- Written Handouts, Interactive Workshop
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Stress Urinary Incontinence
The Prefyx PPS™ System eRegistry
Registry to gather information about the long term use of the Prefyx PPS System for the treatment of Stress Urinary Incontinence (SUI).
- Trial name
- NCT00688181
- Testing
- The Prefyx PPS™ Pre-pubic Sling System
- Where
- 5 sites in United States
- Volunteers
- 44 people
- Sponsor
- Boston Scientific Corporation
Stress Urinary Incontinence
Comparing KIM to TVT Exact Sling
To assess to the non-inferiority of the retropubic Neomedic Knotless Incontinence Mesh (KIM) sling compared to the Gynecare Tension-free Vaginal Tape (TVT) Exact sling.
- Trial name
- NCT04985799
- Testing
- Gynecare TVT Exact Continence System, Neomedic KIM (Knotless Incontinence Mesh)
- Where
- 2 sites in United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Female Stress Urinary Incontinence
Clinical Evaluation of Ajust™ in Stress Urinary Incontinence
The purpose of this study is to assess the overall effectiveness of the Ajust Adjustable Single-Incision Sling in the surgical treatment of female stress urinary incontinence.
- Trial name
- CEASe (NCT01290796)
- Testing
- Ajust Adjustable Single-Incision Sling
- Where
- 6 sites in United States
- Volunteers
- 153 people
- Sponsor
- C. R. Bard