Clinical trials: Stone, Urinary
Urinary Calculi
Use of Alfuzosin in Stone Treatment With ESWL
Urinary tract stones may form in the kidneys or along the ureteric tracts and when left untreated, may result in complications such as pain, bleeding, infection and obstruction.
- Trial name
- NCT00388271
- Testing
- Alfuzosin (Xatral), standard treatment
- Where
- Singapore
- Sponsor
- Singapore General Hospital
Kidney Stone
Robotic-assisted Percutaneous Access
This is a first-in-man (FIM) study to show feasibility and safety profile of the newly developed robotic device for percutaneous access in PCNL surgery.
- Trial name
- NCT04435132
- Testing
- PCL under fluoroscopy with the aid of the robotic device
- Where
- Malaysia
- Volunteers
- 5 people
- Sponsor
- NDR Medical Technology Pte Ltd
Cystinuria
TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study
The goal of this research project is to establish that in short-term use, tolvaptan is a safe and potentially effective new therapy for cystinuria, by conducting a short-term pilot study of the safety and tolerability of this…
- Trial name
- TCUPS (NCT02538016)
- Testing
- Tolvaptan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Caleb Nelson
Renal Calculi
Diagnostic Accuracy of x Ray Kub in Diagnosing Renal Calculi Keeping CT Scan as Gold Standard
In clinical practice both Xray and CT Scan KUB are reliable,however, Ctscan is superior to X ray KUB in detecting renal and ureteric calculi,the reson being stone that are missed by xray KUB are usually small and sould pass…
- Trial name
- NCT06767384
- Testing
- X-ray
- Where
- Pakistan
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- Superior University
Calcium Phosphate Kidney Stones
Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones
This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.
- Trial name
- NCT06003348
- Testing
- OHCit- standard dose, Potassium Citrate, OHCit- low dose
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Calculi, Postoperative Pain
Is it Really Necessary to Insert a Nephrostomy Tube or Double J Stent in Percutaneous Nephrolithotomy?
In this study, investigators aimed to compare the postoperative pain status and comfort situations depending on instruments used in the percutaneous nephrolithotomy operation
- Trial name
- NCT06062849
- Testing
- nephrostomy tube, double J stent, totally tubless
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Bursa City Hospital
Ureteral Calculi, Kidney Stones
Study of Silodosin to Facilitate Passage of Urinary Stones
The purpose of this study is to assess if patients treated with silodosin will have a higher spontaneous passage rate of their ureteral stone than those treated with placebo.
- Conditions
- Ureteral Calculi, Kidney Stones, Urolithiasis
- Trial name
- NCT01144949
- Testing
- silodosin
- Where
- 27 sites in United States
- Volunteers
- 239 people
- Sponsor
- Watson Pharmaceuticals
Kidney Stone, Nephrolithiasis
Pediatric KIDney Stone (PKIDS) Care Improvement Network
The goals of this study are to improve the ability of pediatric patients and their caregivers to select surgical treatment options for kidney stones and to enable urologists to use techniques that result in the best outcomes for…
- Trial name
- PKIDS (NCT04285658)
- Testing
- Ureteroscopy, Percutaneous Nephrolithotomy, Shock Wave Lithotripsy
- Where
- 31 sites in United States, Canada
- Volunteers
- 1,290 people
- Sponsor
- Children's Hospital of Philadelphia
Urinary Stones, Ureteral Calculus
The Usefulness of Flexible Cystoscopy for Preventing Double-J Stent Malposition After Laparoscopic Ureterolithotomy
The aim of this study was to evaluate the role of flexible cystoscopy in preventing malpositioning of the ureteral stent after laparoscopic ureterolithotomy in male patients.
- Trial name
- FC-DM (NCT03150446)
- Testing
- flexible cystoscopy
- Where
- South Korea
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sung Gu Kang
Kidney Calculi
Are There Protective Effects of Antioxidants, Calcium Channel Blocker and Angiotensin Receptor Blocker Against Extracorporeal Shockwaves Lithotripsy Induced Renal Injury?
This study will be conducted to evaluate the protective effects and mechanisms of antioxidants (vitamins A, C, E and Selenium), calcium channel blocker (Verapamil) and angiotensin receptor blocker (Lozartan) against shock wave…
- Trial name
- SWL (NCT01675362)
- Testing
- Antioxidant group, Calcium Channel Blockers, Angiotensin receptor blocker group
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura University
Urinary Stones
Management of Fragments During Ureteroscopy
The purpose of this study is to study the outcome of patients after ureteroscopy in which all fragments remaining after holmium laser lithotripsy were retrieved compared to those where small, insignificant fragments were left for…
- Trial name
- NCT00637650
- Testing
- Ureteroscopy, Holmium Laser lithotripsy and active retrieval of fragments, Ureteroscopy, Holmium laser lithotripsy, no intent to retrieve any remaining fragment
- Where
- Israel
- Sponsor
- The Chaim Sheba Medical Center
Kidney Stone, Retrograde Intrarenal Surgery (RIRS)
Multimodal Opioid-Free Anesthesia in RIRS
The goal of this clinical trial is to evaluate whether a dexmedetomidine-ketamine based opioid-free anesthesia (OFA) protocol can provide effective analgesia compared to conventional fentanyl-based anesthesia in adult patients…
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery (RIRS), Postoperative Pain
- Trial name
- NCT07636070
- Testing
- Dexmedetomidine-Ketamine Opioid-Free Anesthesia, Fentanyl-Based Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- murat sahin
Ureteral Stent-Related Symptoms, Ureteral Calculi
ComfiJ Versus Conventional Double-J Stent for Ureteral Stent Symptoms
This prospective multicenter randomized controlled trial will compare stent-related symptoms after placement of a ComfiJ ureteral stent versus a conventional double-J ureteral stent in adult patients undergoing unilateral…
- Conditions
- Ureteral Stent-Related Symptoms, Ureteral Calculi, Urolithiasis
- Trial name
- COMFIJ-DJS (NCT07627828)
- Testing
- ComfiJ Ureteral Stent, Conventional Double-J Ureteral Stent
- Where
- 3 sites in Egypt
- Volunteers
- 150 people
- Sponsor
- Beni-Suef University
Urolithiasis, Stones, Kidney
Trial of Ureteroscopy vs Steerable Continuous Flow Aspiration Technology
The goal of this clinical trial is to compare Steerable Ureteroscopic Renal Evacuation (SURE) using the CVAC System and standard ureteroscopy (URS) with laser lithotripsy for the treatment of urolithiasis.
- Conditions
- Urolithiasis, Stones, Kidney, Renal Stones, Kidney Stones
- Trial name
- TRUST (NCT07101809)
- Testing
- Steerable Ureteroscopic Renal Evacuation (SURE) using the CVAC System, Standard Ureteroscopy (URS)
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- Calyxo, Inc.
Kidney Stone
Potassium Citrate Supplementation vs. Dietary Counseling
The purpose of this study is to compare the role of potassium citrate supplementation with dietary education versus dietary education alone in the reduction of stone risks and events in patients with predominantly calcium…
- Trial name
- NCT01980004
- Testing
- Potassium Citrate Supplementation, Dietary Education
- Where
- United States
- Sponsor
- University of North Carolina, Chapel Hill
Urinary Bladder Calculi, Bladder Calculi
Transurethral Versus Percutaneous Cystolithotripsy for Bladder Stones in Adults
This study evaluates and compares two minimally invasive surgical approaches for treating bladder stones in adult patients: transurethral cystolithotripsy (TUCL) and percutaneous cystolithotripsy (PCCL).
- Conditions
- Urinary Bladder Calculi, Bladder Calculi, Urolithiasis
- Trial name
- NCT07810582
- Testing
- Transurethral Cystolithotripsy, Percutaneous Cystolithotripsy
- Volunteers
- 50 people
- Sponsor
- Assiut University
Kidney Calculi, Ureteral Calculi
Impact of Humid-Heat on Gut-Tryptophan-Stone Pathway
Investigating the differences in gut microbiota composition and tryptophan metabolite levels between kidney stone patients and healthy individuals, with special focus on: 1.
- Trial name
- NCT07043374
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Renal Calculi, Renal Anomaly
RIRS for Treatment of Stones in Congenital Anomalous Kidneys
The anatomic renal abnormalities like altered spatial relations with adjacent organs, abnormal calyceal orientation, and anomalous vascular patterns make the active treatment of stones in the congenitally malformed kidney a great…
- Trial name
- NCT05240170
- Testing
- RIRS, SWL
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Al-Azhar University
Renal Calculi, Postoperative Pain
Efficacy of Liposomal Bupivacaine for Pain Control After Percutaneous Nephrostolithotomy
Percutaneous nephrostolithotomy (PCNL) is a common endoscopic procedure performed for upper urinary tract calculus disease. Despite being minimally invasive, it is associated with significant postoperative pain, often…
- Trial name
- NCT03043027
- Testing
- liposomal bupivicaine, Bupivacaine, Saline Solution
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Renal Calculi
Role of Pre-stenting Before Retrograde Intrarenal Surgery With Miniaturized Flexible Ureteroscopes
This prospective randomized controlled trial will compare retrograde intrarenal surgery performed after routine preoperative ureteral stenting with direct retrograde intrarenal surgery without planned preoperative stenting in…
- Trial name
- NCT07773090
- Testing
- Preoperative double-J ureteral stenting followed by retrograde intrarenal surgery, Direct retrograde intrarenal surgery without planned preoperative ureteral stenting
- Where
- Egypt
- Volunteers
- 270 people
- Sponsor
- Al-Azhar University