Clinical trials: Stillbirth and Fetal Death
Assessment of Fetal Movement, Pregnancy
Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements
The surveillance of pregnancies at risk for fetal loss secondary to high-risk maternal or fetal conditions remains a mainstay of perinatal care.
- Conditions
- Assessment of Fetal Movement, Pregnancy, Pregnancy Complications, Pregnancy Complications Affecting Fetus (Diagnosis)
- Trial name
- WWA (NCT07626112)
- Testing
- Smartphone Application
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Kenneth Moise MD
Stillbirth and Fetal Death, Miscarriages
Parents' Experience of Child Loss During Pregnancy or Birth
The investigators are conducting a participatory study with and for parents after child loss during pregnancy or birth. Their aim is to develop treatment recommendations for healthcare professional.
- Conditions
- Stillbirth and Fetal Death, Miscarriages, Experience
- Trial name
- NCT06771661
- Testing
- Workshops, Focus group interviews, Narrative interviews
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Fritz Sterr
Abortion, Stillbirth
Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation
People seeking second-trimester dilation and evacuation (D\&E) procedures are often facing profoundly challenging circumstances, including desired pregnancies complicated by fetal anomalies or demise, serious maternal health…
- Conditions
- Abortion, Stillbirth, PTSD (Childbirth-Related), Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT07537894
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg
- Where
- United States
- Sponsor
- Stanford University
High Risk Pregnancy, Congenital Heart Disease
Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise
Each year world-wide, 2.5 million fetuses die unexpectedly in the last half of pregnancy, 25,000 in the United States, making fetal demise ten-times more common than Sudden Infant Death Syndrome.
- Conditions
- High Risk Pregnancy, Congenital Heart Disease, Fetal Hydrops, Twin Monochorionic Monoamniotic Placenta
- Trial name
- NCT03775954
- Testing
- Fetal Magnetocardiogram and Neonatal Electrocardiogram, Substudy only: Maternal/Infant Pharmacogenomic assessment postnatally
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Medical College of Wisconsin
Stillbirth and Fetal Death, Perinatal Death
Mothers Working to Prevent Early Stillbirth Study 20-28
This project aims to identify factors linked to pregnancy losses occurring between 20 and 28 weeks of pregnancy that can be modified by changing mother's behaviour or healthcare provision.
- Trial name
- MiNESS20-28 (NCT06005272)
- Testing
- Questionnaire
- Where
- United Kingdom
- Volunteers
- 948 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Stillbirth, Fetal Death
Investigating the Structured Use of Ultrasound Scanning for Fetal Growth
Fetal growth restriction during pregnancy represents one of the biggest risk factors for stillbirth (Gardosi et al, 2013), with 'about one in three term, normally formed antepartum stillbirths are related to abnormalities of…
- Conditions
- Stillbirth, Fetal Death, Fetal Growth Retardation, Small for Gestational Age
- Trial name
- OxGRIP (NCT03662178)
- Where
- United Kingdom
- Volunteers
- 56,000 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
Pregnancy, Pregnancy Complications
AI-POCUS for Maternal and Neonatal Health in Ethiopia
Maternal and neonatal health remains one of the most pressing global health challenges, particularly in low- and middle-income countries (LMICs).
- Conditions
- Pregnancy, Pregnancy Complications, Preterm Birth, Fetal Growth Restriction
- Trial name
- AIM-ETH (NCT07171086)
- Testing
- AI-POCUS (BabyChecker, Delft Imaging), AI-POCUS (Edan, China)
- Where
- Ethiopia
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Tsinghua University
Fetal Growth Retardation, Stillbirth and Fetal Death
Antenatal Melatonin Supplementation for Neuroprotection in Fetal Growth Restriction
Fetal growth restriction (FGR) is a significant health care issue, affecting 20,000 Australian pregnancies every year. Undetected FGR is one of the key risk factors for stillbirth, but FGR can also cause significant impairments…
- Conditions
- Fetal Growth Retardation, Stillbirth and Fetal Death, Pregnancy Preterm
- Trial name
- PROTECTMe (NCT05651347)
- Testing
- Melatonin 10 MG
- Where
- 12 sites in Australia, New Zealand
- Volunteers
- 336 people, healthy volunteers welcome
- Sponsor
- Monash University
Intrauterine Fetal Death
Uterine Doppler As StillbirthPredictor
The goal of this observational study is to define the predictive value of intrauterine fetal death for different longitudinal patterns of uterine artery Doppler indices (UtA-PI, UtA-RI and notch) from the second and third…
- Trial name
- NCT06825481
- Where
- Italy
- Volunteers
- 4,863 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Chronic Histiocytic Intervillositis, Intrauterine Growth Retardation
Exploration of Allograft Humoral Rejection in Chronic Histiocytic Intervillositis
Chronic histiocytic intervillositis (CHI) is a rare condition with an incidence of 5 in 10,000 pregnancies. This rare condition is associated with placental inflammatory lesions leading to severe and recurrent obstetrical…
- Conditions
- Chronic Histiocytic Intervillositis, Intrauterine Growth Retardation, Fetal Death in Utero, Miscarriage
- Trial name
- RH-PL (NCT05936333)
- Testing
- Biological collection
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Stillbirth and Fetal Death
Intervention to Prevent Mental Health Disorders of Women and Their Partners Who Experienced Pregnancy Loss
The goal of this clinical trial is to test impact of a multiprofessional intervention in mothers and partners who suffer a pregnancy loss.
- Trial name
- Enzo (NCT06340555)
- Testing
- GUIA ATENCION MULTIDISCIPLINAR SANT BOI, USUAL CARE
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Fundació Sant Joan de Déu
Pregnancy Complications, Pregnancy Outcome
BioThrax® (Anthrax) Vaccine in Pregnancy Registry
The purpose of this study is to determine if inadvertent receipt of the BioThrax vaccine during pregnancy is independently associated with adverse maternal, pregnancy, or infant health outcomes.
- Conditions
- Pregnancy Complications, Pregnancy Outcome, Congenital Abnormalities
- Trial name
- NCT01653392
- Testing
- Observational Intervention
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Emergent BioSolutions
Fetal Death in Utero
Fetal Death in Utero in the Internship Experience of Midwifery Students : an Unavoidable Experience?
Fetal death in utero and the psychological and professional impact it could have on the midwifery student in training. Fetal death in utero corresponds to the spontaneous cessation of cardiac activity, from 14 weeks of…
- Trial name
- MFU (NCT06202508)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
COVID-19, COVID-19 Pneumonia
Effect of Covid 19 Infection on Fetomaternal Outcome
The novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was discovered for the first time in December 2019 in Wuhan (China) and the disease it causes is called coronavirus disease 2019…
- Conditions
- COVID-19, COVID-19 Pneumonia, Fetal Growth Retardation
- Trial name
- NCT05160649
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Fayoum University
Intrauterine Fetal Demise, Fetal Death
Mifepristone Induction for Fetal Demise
Methods: Double blinded, randomized controlled trial with 1:1 allocation of mifepristone or placebo at initiation of induction of labor for fetal demise 20 weeks estimated gestational age or greater.
- Trial name
- MIFD (NCT02620904)
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Fetal Growth Retardation, Stillbirth
Prediction of Late Fetal Growth Restriction Using Cerebroplacental Ratio
To investigate the screening performance of CPR and biophysical profile score for the prediction of composite of adverse neonatal morbidity and mortality and operative delivery (CS or instrumental) for intrapartum fetal distress…
- Conditions
- Fetal Growth Retardation, Stillbirth, Neonatal Respiratory Failure, Neonatal Death
- Trial name
- NCT04640467
- Testing
- Biophsical profile, Cerebroplacental ratio
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Stillbirth and Fetal Death, Termination of Pregnancy
A Feasibility Study of Virtopsy With Tissue Sampling in Besancon University Hospital
The aim of this project is to assess the feasibility of a new local post mortem procedure at Besançon University Hospital : Virtopsy+, magnetic resonance (MR) imaging with tissue sampling of the fetus and newborns.
- Conditions
- Stillbirth and Fetal Death, Termination of Pregnancy, Neonatal Death
- Trial name
- VIRTOPSY+ (NCT03877900)
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Intrauterine Fetal Death
Causes of Fetal Death: Comparison of Diagnostic Accuracy Between Extensive and Selective Protocol Testing
Intrauterine fetal death (IUFD) is defined as the occurrence of fetal death at >20 weeks' gestation. IUFD affects about 1 in 160 pregnancies (6-7 per 1000 births).
- Trial name
- EMIBICI (NCT03214328)
- Testing
- Determination of causes of fetal death
- Where
- France
- Volunteers
- 602 people
- Sponsor
- University Hospital, Rouen
Spontaneous Abortion, Fetal Death
Environmental Factors and Embryonic Development Project
The Environmental Factors and Embryonic Development Project was set up to investigate environmental exposures and behavioral factors responsible for embryonic dysplasia and gestational complications in pregnant women.
- Conditions
- Spontaneous Abortion, Fetal Death, Stillbirth, Birth Defects
- Trial name
- EFED (NCT04182503)
- Testing
- No intervention
- Where
- 19 sites in China
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Jinling Hospital, China
Advanced Maternal Age Pregnancy, High Risk Pregnancy
University Hospital Advanced Age Pregnant Cohort
The University Hospital Advanced Age Pregnant (UNIHOPE) Cohort is the major part of the National Key Research and Development Program on Reproductive Health \& Major Birth Defects Control and Prevention Project, which is funded…
- Conditions
- Advanced Maternal Age Pregnancy, High Risk Pregnancy, Perinatal Death, Maternal Death
- Trial name
- UNIHOPE (NCT03220750)
- Where
- 9 sites in China
- Volunteers
- 22,000 people, healthy volunteers welcome
- Sponsor
- Peking University