Clinical trials: Stillbirth
Maternal Health, Neonatal Health
Improving Maternal and Neonatal Care-seeking Through a Video-informed Training Session During the Third Trimester of Pregnancy
This study is a randomized controlled trial evaluating the impact of a video-informed training session on maternal and newborn health care seeking in rural Côte d'Ivoire.
- Conditions
- Maternal Health, Neonatal Health, Pregnancy, Postpartum Care
- Trial name
- Taabo T3 (NCT07819201)
- Testing
- Information video and planning session
- Where
- Côte d’Ivoire
- Volunteers
- 800 people
- Sponsor
- Swiss Tropical & Public Health Institute
Assessment of Fetal Movement, Pregnancy
Feasibility Trial of the Womb Watch Smartphone App To Assess Fetal Movements
The surveillance of pregnancies at risk for fetal loss secondary to high-risk maternal or fetal conditions remains a mainstay of perinatal care.
- Conditions
- Assessment of Fetal Movement, Pregnancy, Pregnancy Complications, Pregnancy Complications Affecting Fetus (Diagnosis)
- Trial name
- WWA (NCT07626112)
- Testing
- Smartphone Application
- Where
- 3 sites in United States
- Volunteers
- 60 people
- Sponsor
- Kenneth Moise MD
Stillbirth and Fetal Death, Miscarriages
Parents' Experience of Child Loss During Pregnancy or Birth
The investigators are conducting a participatory study with and for parents after child loss during pregnancy or birth. Their aim is to develop treatment recommendations for healthcare professional.
- Conditions
- Stillbirth and Fetal Death, Miscarriages, Experience
- Trial name
- NCT06771661
- Testing
- Workshops, Focus group interviews, Narrative interviews
- Where
- Germany
- Volunteers
- 46 people
- Sponsor
- Fritz Sterr
Preeclampsia
Comparison of High- Versus Low-Dose Aspirin for Pregnancy Outcomes in Women at High Risk of Preeclampsia
The goal of this randomized clinical trial is to compare the effects of two doses of aspirin, 75 mg and 150 mg, in pregnant women who are at high risk of developing preeclampsia. The main question the study aims to answer is: 1.
- Trial name
- NCT07779057
- Testing
- Aspirin
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Medicare Hospital (Pvt) Limited
Small for Gestational Age at Delivery, Gestational Weight Gain
BEP Targeting Strategies in Ethiopia
The goal of this randomized effectiveness study is to evaluate the different targeting strategies for the delivery of balanced energy and protein (BEP) supplements among pregnant women in Addis Ababa, Ethiopia.
- Conditions
- Small for Gestational Age at Delivery, Gestational Weight Gain, Stillbirth, Preterm Birth
- Trial name
- BEP (NCT06125860)
- Testing
- Targeted BEP based on baseline nutritional status, Targeted BEP based on baseline nutritional status and monthly GWG monitoring, Universal BEP
- Where
- Ethiopia
- Volunteers
- 7,851 people
- Sponsor
- Harvard School of Public Health (HSPH)
Perinatal Death, Hypertension, Pregnancy-Induced
Pregnancy in the Context of Urbanicity and Climate Change. The Overall Aim of the Project is to Co-create, Implement, and Test New Clinical Guidelines in Order to Improve the Quality of Care in Antenatal Clinics in the Context of Urbanisation and Climate Change in Dar es Salaam, Tanzania.
Tanzania's population is growing quickly, and Dar es Salaam is one of the fastest-growing cities in the world. At the same time, the city is increasingly affected by very hot weather, flooding, and air pollution.
- Conditions
- Perinatal Death, Hypertension, Pregnancy-Induced, Abortion, Spontaneous, Stillbirth
- Trial name
- NCT07751432
- Testing
- CC-ANC intervention group.
- Where
- Tanzania
- Volunteers
- 1,060 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Stillbirths and Infant Mortality
Oral Azithromycin to Prevent Stillbirths and Infant Mortality in Mali
The double blind randomized controlled trial will assess the efficacy of oral azithromycin administered to pregnant women and/or infants during routine care in preventing stillbirths and mortality through 6-12 months of age in…
- Trial name
- SANTE (NCT03909737)
- Testing
- Azithromycin to pregnant women, Azithromycin to infants, No intervention to pregnant women
- Where
- Mali
- Volunteers
- 99,700 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Stillbirth
Research On Advanced Diagnostics and Management of All Pregnancies to Prevent Stillbirth (ROADMAPS)
The primary objective of the Stillbirth Research Consortium (SBRC) longitudinal cohort study is to develop and evaluate a robust multivariable prediction model to identify pregnancies at <14 weeks gestation that are at increased…
- Trial name
- ROADMAPS (NCT07745101)
- Where
- 5 sites in United States
- Volunteers
- 7,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Adverse Pregnancy Outcome
Using Placental Pathology to Prevent Recurrent Adverse Pregnancy Outcomes: A Pilot Project
The goal of this randomized clinical trial is to evaluate if we can use placental pathology in a prior pregnancy which had an adverse outcome, such as early delivery, stillbirth, a baby born smaller than expected, or severe forms…
- Trial name
- NCT06004674
- Testing
- Lovenox 40mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Endeavor Health
Abortion, Stillbirth
Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation
People seeking second-trimester dilation and evacuation (D\&E) procedures are often facing profoundly challenging circumstances, including desired pregnancies complicated by fetal anomalies or demise, serious maternal health…
- Conditions
- Abortion, Stillbirth, PTSD (Childbirth-Related), Grief (Traumatic Grief and Existential Grief)
- Trial name
- NCT07537894
- Testing
- Dexmedetomidine (IV) 0.5 mcg/kg
- Where
- United States
- Sponsor
- Stanford University
Grief, Post Traumatic Stress Disorder
Walk With Me (WWM) for Perinatal Grief
The goal of this clinical trial is to learn if the Along With Me web-based intervention works to decrease posttraumatic stress symptoms and suicidal ideation among bereaved parents following pregnancy and early infant loss.
- Conditions
- Grief, Post Traumatic Stress Disorder, Suicidal Ideation, Miscarriage
- Trial name
- PeriGrief-II (NCT07011940)
- Testing
- Along With Me, Peer Guide
- Where
- 2 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Oregon Research Behavioral Intervention Strategies, Inc.
Cardiovascular Diseases
Continuation of the nuMoM2b Heart Health Study
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in U.S. women at all ages, and large knowledge gaps exist in CVD predictive and preventative strategies for women.
- Trial name
- nuMoM2b-HHS2 (NCT05472597)
- Where
- 14 sites in United States
- Volunteers
- 4,048 people, healthy volunteers welcome
- Sponsor
- RTI International
Stillbirth and Neonatal Mortality, Perinatal Mortality
Perinatal Mortality Outcomes Through Household Infection Pathways
The goal of this trial is to learn if replacing household soil floors with concrete floors can prevent deaths of infants around the time of birth, including stillbirths and deaths in the first month of life in rural Bangladesh.
- Conditions
- Stillbirth and Neonatal Mortality, Perinatal Mortality, Infant Mortality, Child Mortality
- Trial name
- POTH (NCT07620613)
- Testing
- Concrete household floor
- Where
- Bangladesh
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Stanford University
Caesarean Section;Stillbirth
Neonatal Evaluation of Norepinephrine Infusion in Spinal Anesthesia for Cesarean Section
This retrospective study aims to evaluate the fate of children born by cesarean section under spinal anesthesia with or without norepinephrine as vasopressor support for anesthesia.
- Trial name
- NECS (NCT04245891)
- Where
- France
- Volunteers
- 265 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Fetal Growth Restriction (FGR), Placental Insufficiency
Placental Imaging Techniques
The goal of this proof-of-concept, case-control, clinical trial is to evaluate the efficacy of using two newer ultrasound technologies, quantitative ultrasound (QUS) and ultrafast power Doppler imaging (uPDI), to evaluate the…
- Conditions
- Fetal Growth Restriction (FGR), Placental Insufficiency, Preeclampsia, Still Births
- Trial name
- NCT06861309
- Testing
- ultrafast power Doppler imaging (uPDI) / quantitative ultrasound (QUS)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Carilion Clinic
Malaria,Falciparum, Malaria in Pregnancy
Improving Neonatal Health Through Rapid Malaria Testing in Early Pregnancy With High-Sensitivity Diagnostics
The purpose of the INTREPiD study is to compare 1st trimester screening for malaria parasites with a high-sensitivity malaria rapid diagnostic test followed by treatment of test-positive women with artemether-lumefantrine (AL)…
- Conditions
- Malaria,Falciparum, Malaria in Pregnancy, Malaria in Childbirth, Pregnancy
- Trial name
- INTREPiD (NCT05757167)
- Testing
- Malaria High-Sensitivity Rapid Diagnostic Test (HS-RDT), Artemether-lumefantrine (AL)
- Where
- 2 sites in Democratic Republic of the Congo, Kenya
- Volunteers
- 2,174 people
- Sponsor
- Duke University
Preeclampsia (PE), Fetal Growth Restriction
The Combined First Trimester Screening
The project is a national, prospective, multicenter pilot project. The project is focus on setting up the combined first trimester screening in the Czech Republic.
- Conditions
- Preeclampsia (PE), Fetal Growth Restriction, Congenital Abnormalities, Preterm Labor
- Trial name
- NCT07015203
- Where
- 3 sites in Czechia
- Volunteers
- 2,000 people
- Sponsor
- Institute of Health Information and Statistics of the Czech Republic
Preterm Delivery, Obstetrical Complications
Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial
This is a phase-III multi-center double-blind randomized clinical trial of 1,800 individuals with a history of prior preterm birth at less than 35 weeks gestation who are randomized to either 162 mg aspirin or 81 mg aspirin…
- Trial name
- ADEPT (NCT06980025)
- Testing
- 162mg Aspirin, 81mg Aspirin
- Where
- 14 sites in United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Stillbirth, Perinatal Death
A Feasibility Randomised Control Trial to Evaluate Early Perinatal Bereavement Counselling for Parents Who Have Experienced a Perinatal Death
The goal of this feasibility randomised control trial is to determine if a trial to evaluate perinatal bereavement counselling for parents who have experienced a perinatal death is feasible.
- Conditions
- Stillbirth, Perinatal Death, Psychological, Grief
- Trial name
- PEARL-C (NCT07494760)
- Testing
- Bereavement Counselling, Usual bereavement care
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Stillbirth
The Tommy's National Rainbow Clinic Study
The death of a baby before or shortly after birth affects approximately 1 in every 250 pregnancies in the UK meaning that over 4,000 parents experience the death of a baby each year in the UK.
- Trial name
- NCT04393259
- Testing
- Rainbow Clinic Model of Antenatal Care
- Where
- United Kingdom
- Volunteers
- 500 people
- Sponsor
- University of Manchester