Clinical trials: Startle Response, active
Anxiety
Effect of cTBS on Startle and TMS-evoked BOLD
The right dorsolateral prefrontal cortex (dlPFC) is increasingly being targeted with transcranial magnetic stimulation (TMS) to reduce anxiety expression; however, there is little mechanistic evidence supporting an optimized…
- Trial name
- NCT07415772
- Testing
- Active TMS
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Depression, Anxiety, Fear
Processes and Circuitry Underlying Threat Sensitivity as a Treatment Target for Co-morbid Anxiety and Depression
This mechanistic study uses an anti anxiety drug and brain imaging to study the threat processing system and associated brain circuits in people with depression, anxiety disorders and comorbid depression and anxiety disorders.
- Conditions
- Depression, Anxiety, Fear, Depression, Anxiety and Fear
- Trial name
- NCT06004115
- Testing
- Lorazepam
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Laureate Institute for Brain Research, Inc.