Clinical trials: Stability
Mechanical Low Back Pain, Respiratory Functions
Core Stability Exercise Versus Diaphragmatic Release on Respiratory Functions on Physical Therapists With Low Back Pain
To compare between core stability exercise and diaphragmatic release on respiratory functions on physical therapists with low back pain.
- Trial name
- NCT05860283
- Testing
- Core stabilization exercise using pressure biofeedback unit, Diaphragmatic release technique
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Myocardial Infarction, Heart Failure, Systolic
MCNAIR Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation
Cardiac rehabilitation is a medically recommended program for patients with certain heart conditions. It includes exercise training, health education, and counseling.
- Conditions
- Myocardial Infarction, Heart Failure, Systolic, Heart Valve Diseases, Angina, Stable
- Trial name
- NCT05933083
- Testing
- In-person cardiac rehabilitation, Telehealth cardiac rehabilitation
- Where
- 5 sites in United States
- Volunteers
- 516 people
- Sponsor
- University of California, San Francisco
Chronic Non-Specific Low Back Pain
Dynamic Versus Traditional Core Strengthening Exercises in Patients With Chronic Non-specific Low Back Pain
This research investigated the effectiveness of two different types of core strengthening exercises: dynamic versus traditional exercises.
- Trial name
- CNLBP (NCT07884396)
- Testing
- Routine Physiotherapy, Dynamic Core Strengthening Exercises, Traditional Core Strengthening Exercises
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- University of Lahore
Pulmonary Arterial Hypertension
Tezosentan in Pulmonary Arterial Hypertension
Multicenter, Open-label, Non-comparative, Proof-of-concept, Phase 2a Study to Evaluate the Effect of a Single Infusion of Tezosentan on Pulmonary Vascular Resistance in Patients With Stable, Chronic Pulmonary Arterial…
- Trial name
- NCT01077297
- Testing
- Tezosentan
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 3 people
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Dry Eye
I-DROP MGD Symptomatic Relief and Tear Film Stability
The objective of the study is to compare the difference in tear film stability and symptomatic relief between I-DROP MGD and another commercially available drop in the Canadian market.
- Trial name
- NCT05011708
- Testing
- I-DROP MGD, Thealoz Duo
- Where
- 2 sites in Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- I-MED Pharma
HIV Infections
A Phase II Study of Low-Dose Interleukin-2 by Subcutaneous Injection in Combination With Antiretroviral Therapy Versus Antiretroviral Therapy Alone in Patients With HIV-1 Infection and at Least 3 Months Stable Antiretroviral Therapy
PRIMARY: To examine the effect of aldesleukin ( IL-2 ) on viral activity in the blood. To determine the safety of low-dose IL-2 in combination with antiretroviral therapy versus antiretroviral therapy alone.
- Trial name
- NCT00000820
- Testing
- Aldesleukin
- Where
- 10 sites in United States
- Volunteers
- 104 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
PAH
PRIMEx - A Study of 2 Doses of Oral CXA-10 in Pulmonary Arterial Hypertension (PAH)
This is a multicenter double-blind, placebo-controlled study to evaluate the safety, efficacy and pharmacokinetics of 2 doses of CXA-10 on stable background therapy in 96 subjects 18 to 80 years of age with PAH.
- Trial name
- PAH (NCT03449524)
- Testing
- 75mg CXA-10, 150mg CXA-10
- Where
- 46 sites in United States, United Kingdom
- Volunteers
- 69 people
- Sponsor
- Complexa, Inc.
Autoimmune Diseases
Withdraw Drug in Stable IgG4-Related Disease
Evaluation and prediction of relapse risk after glucocorticoid or immunosuppressant withdrawal in patients with stable IgG4 related disease: a prospective cohort study from china.
- Trial name
- NCT04124861
- Testing
- Drug free, IS monotherapy and GC combined with IS
- Where
- China
- Volunteers
- 138 people
- Sponsor
- Peking Union Medical College Hospital
Iron Deficiency (ID), Iron Absorption
Iron Absorption From Plant Heme Iron
Heme, an iron protoporphyin IX complex, consists of a ferrous ion captured in a porphyrin ring acting as a tetradentate ligand. The unique features of heme iron -its unusually high absorption in foods and its resistance to…
- Trial name
- PHIA (NCT07143890)
- Testing
- Iron chlorophyllin + no-matrix, SoyHb + no-matrix, FeSO4 + no-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Jaw, Edentulous, Partially
Study on OsseoSpeed™ Implants in Patients Missing 2-5 Teeth in the Posterior Lower Jaw, Restored With Permanent Teeth Attached 6-7 Weeks Later
The purpose of the study is to evaluate Astra Tech Dental Implant System, Fixture Osseospeed™, in patients with tooth loss in the posterior mandible in an early loading protocol.
- Trial name
- NCT00711425
- Testing
- OsseoSpeed™
- Where
- 3 sites in United States, Germany
- Volunteers
- 45 people
- Sponsor
- Dentsply Sirona Implants and Consumables
Metastatic Colorectal Cancer, Microsatellite Stable Colorectal Carcinoma
Cadonilimab in Combination With Bevacizumab and FOLFOX Regimen for the First-Line Treatment of Advanced Unresectable MSS-Type, RAS-Mutated Metastatic Colorectal Cancer
The dual immunotherapy regimen significantly outperformed previous chemotherapy or immunomonotherapy for MSS type advanced CRC in two key efficacy indicators, ORR and PFS.
- Conditions
- Metastatic Colorectal Cancer, Microsatellite Stable Colorectal Carcinoma, RAS Mutation, Cadonilimab
- Trial name
- NCT06218810
- Testing
- Cadonilimab + bevacizumab + FOLFOX
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Fudan University
Chronic Heart Failure
Clinical Outcome of Electrical Transcutaneous Auricular Vagal Stimulation in Patients With Stable Symptomatic Chronic Heart Failure
This study aims to investigate whether electrical vagus nerve stimulation in the auricle has an impact on the clinical presentation of heart failure.
- Trial name
- COETAV (NCT06950320)
- Testing
- P-STIM (Biegler, Mauerbach, Austria) is a battery-operated micro-stimulation appliance
- Where
- Austria
- Volunteers
- 13 people
- Sponsor
- Medical University of Vienna
Stable Angina
Fractional FLow Reserve And IVUS for Clinical OUtcomes in Patients With InteRmediate Stenosis
To compare the safety and efficacy of FFR (fractional flow reserve)-guided percutaneous coronary intervention (PCI) strategy with IVUS (intravascular ultrasound [IVUS])-guided PCI in patients with intermediate coronary stenosis.
- Trial name
- FLAVOUR (NCT02673424)
- Testing
- FFR-guided stenting, IVUS-guided stenting
- Where
- 5 sites in China, South Korea
- Volunteers
- 1,700 people
- Sponsor
- Seoul National University Hospital
Spacing of Anterior Teeth
Color Stability of Sectional and Full Glass Ceramic Laminate Veneer
The aim of the study is to evaluate the color stability of full and sectional glass ceramic laminate veneer as esthetic failure is reported to be common failure in laminate following clinical service.
- Trial name
- NCT06470945
- Testing
- Glass ceramic sectional veneer, Glass ceramic laminate veneer
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Dislocated Clavicular Fracture Treated With Elastic Stable Intramedullary Nailing
Elastic Stable Intramedullary Nailing of Dislocated Clavicle Fractures in Children
Most Clavicular Fractures in Children can be Treated Conservatively. Our Own Study showed a Benefit towards Much Lower Pain and Better Cosmesis in Adolescents when Treated with Elastic Stable Intramedullary Nailing.
- Trial name
- ESIN clavicle (NCT01325129)
- Where
- Germany
- Volunteers
- 20 people
- Sponsor
- University of Luebeck
Health Adult Subjects, Adults
Musical Stimulation Intensity and Postural Control (MUSIC-POST)
This study aims to investigate the effects of musical stimulation intensity on postural control in athletes using a virtual reality-based (VR) static posturography system.
- Conditions
- Health Adult Subjects, Adults, Athlete
- Trial name
- MUSIC-POST (NCT07260331)
- Testing
- Virtual Reality-Based Auditory Stimulation
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hanifi Korkmaz
Orthodontic Appliance Complication
Miniscrews Primary Stability
Orthodontic Miniscrew primary stability is essential for success and long term results. The aim of the present study is to evaluate Bone Properties and Torque insertion values and how they could be related to primary stability…
- Trial name
- NCT03696511
- Testing
- Orthodontic miniscrew insertion
- Where
- 3 sites in Italy, Spain
- Volunteers
- 30 people
- Sponsor
- University of Genova
Elderly Subjects 65 Years and Older, Healthy or With a Stable Disease and Treatment.
A Study to Assess Safety and Tolerability as Well as Absorption and Excretion of TC-5214 in Medically Stable Elderly Subjects
The purpose of the study is to assess safety, tolerability and pharmacokinetics of TC-5214 in medically stable elderly subjects following multiple oral doses.
- Trial name
- NCT01239771
- Testing
- TC-5214
- Where
- Sweden
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
HIV-1-infection
Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen (ARTISTRY-1)
The goal of this clinical study is to learn more about the effects of switching to the study drugs, bictegravir (BIC) plus lenacapavir (LEN), versus current therapy (Phase 2) and BIC/LEN fixed-dose combination (FDC) versus…
- Trial name
- ARTISTRY-1 (NCT05502341)
- Testing
- Bictegravir, Lenacapavir, BIC/LEN FDC
- Where
- 94 sites in United States, Argentina and 13 more
- Volunteers
- 689 people
- Sponsor
- Gilead Sciences
Volunteers on Chronic, Stable Antipsychotic Regimens
Staccato Loxapine Multidose PK
The objectives of this trial are to assess the safety, tolerability, and pharmacokinetics of multiple inhaled doses of Staccato Loxapine.
- Trial name
- NCT00555412
- Testing
- A - 10 mg loxapine q 4 h x 3 (30 mg total), B - 10 mg x 1, 5 mg x 2 loxapine q 4 h (20 mg total), C - 5 mg loxapine q 4 h x 3 (15 mg total)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Alexza Pharmaceuticals, Inc.