Clinical trials: Splenectomy
Overwhelming Post-Splenectomy Infection
Splenic Function After Spleen-Preserving Distal Pancreatectomy With Excision of Splenic Artery and Vein
The spleen may be removed due to benign hematologic disorders, such as idiopathic thrombocytopenic purpura and hereditary spherocytosis, or malignancies, such as lymphomas and leukemias.
- Trial name
- NCT00778362
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Grade III Traumatic Splenic Injury in Hemodynamically Stable Patients
Traumatic Injury of Spleen:Laparoscopic Splenectomy Vs Splenic Artery Embolization
The goal of this clinical trial is selection of the best method in management of grade 3 traumatic Splenic Injury in Hemodynamically Stable Patients thus improving the quality of life and clinical outcome.
- Trial name
- NCT07274007
- Testing
- Laparoscopic Splenectomy vs splenic Artery Embolization
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Pancreatic Fistula, Distal Pancreatectomy Complications
An Evaluation of a New Technique Utilizing a Biologic Glue and Tissue Patch to Seal the Cut Edge of the Pancreas Following Removal of the Tail of the Pancreas
The purpose of this trial is to determine whether the use of an autologous falciform ligament patch combined with fibrin glue will reduce the rate of pancreatic fistula in patients completing distal pancreatectomy.
- Conditions
- Pancreatic Fistula, Distal Pancreatectomy Complications, Falciform Patch Pancreatic Closure, Fibrin Glue Pancreatic Closure
- Trial name
- NCT00889213
- Testing
- Falciform patch and fibrin glue application, standard pancreatic closure
- Where
- 2 sites in United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Thrombocytopenia, Splenectomy
Evaluation of Immune Status Before and After Splenectomy in Immune Thrombocytopenia Patients
Evaluation of immune status before and after splenectomy in immune thrombocytopenia patients.
- Trial name
- NCT03998059
- Testing
- splenectomy
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Splenectomy; Status
Meningococcal B Vaccine in Patients with Asplenia
Patients without a spleen (asplenia) experience an increased risk for septicaemia from encapsulated bacteria, which is associated with a high mortality rate.
- Trial name
- NCT06025487
- Testing
- Bexsero
- Where
- Austria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Splenectomy; Status, Asplenia
Development of an Italian Questionnaire for Splenectomized Patients Using a Delphi Consensus Method
This study aims to develop an Italian-language questionnaire assessing awareness, knowledge of infectious risk prevention strategies, and vaccination attitudes among splenectomized individuals.
- Conditions
- Splenectomy; Status, Asplenia, Splenectomized Patients
- Trial name
- NCT07428005
- Testing
- Delphi Consensus Process
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Gut Microbiota, Spleen Injury
Microbiota is Related With Increasing Infection Rates After Splenectomy
Studies has shown an increasingly infection rate after splenectomy, and there is a potential correlation between microbiota and immune system.
- Conditions
- Gut Microbiota, Spleen Injury, Infection
- Trial name
- NCT03420599
- Testing
- splenectomy
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Harbin Medical University
Splenectomy; Status
A Nationwide Italian Survey on Asplenia
Spleen is involved in several functions, such as the production of protective antibodies, the removal of unwanted particulate matter from the blood (eg bacteria) and also the storing of blood cells, especially white cells and…
- Trial name
- NCT03571399
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Società Italiana Talassemie ed Emoglobinopatie
Portal Hypertension, Liver Cirrhosis
Laparoscopic Versus Open Devascularization for Portal Hypertension, a Randomized Controlled Trial
Many patients with portal hypertension require surgical treatment each year,and Hassab's operation, or esophagogastric devascularization and splenectomy, is an elective procedure.
- Trial name
- NCT02178319
- Testing
- open surgical procedure, laparoscopic surgical procedure
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University