Clinical trials: Spine Injury
Trauma
Evaluation of Usefulness of Contrast Enhanced MRI in Evaluation of Spine Trauma: Prospective Study
Non-contrast MRI with T2 fat suppression has been a useful imaging modality in evaluation spinal trauma. However, the role of contrast enhancement has not investigated in patients with spinal trauma.
- Trial name
- NCT01880944
- Testing
- NC-MRI, CE-MRI
- Where
- 2 sites in South Korea
- Volunteers
- 300 people
- Sponsor
- Seoul National University Bundang Hospital
Spinal Injuries
Telemonitored Exercise to Attenuate Metabolic Dysregulation in Spinal Cord Injury
The purpose of this research is to test the health benefits of using functional electrical stimulation for lower extremity exercise at home.
- Trial name
- TEAM-SCI (NCT05597176)
- Testing
- Spinal Cord Injury Exercise Group
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Miami
Injuries, Spinal Cord
Diaphragm Pacing After Spinal Cord Injury
Respiratory dysfunction is the leading cause of death in individuals with spinal cord injuries (SCIs). Nearly one quarter of all SCI cases involve injury to the upper spinal cord segments which impairs neural activation of the…
- Trial name
- NCT02556125
- Testing
- Diaphragm pacing
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- University of Florida
Traumatic Vertebral Fractures, Compression Fractures of the Spine
Comparison of Three Treatment Strategies for Traumatic AO Type A1 Vertebral Fractures
This retrospective study evaluates three different treatment approaches used for traumatic AO Spine Type A1 (A1) vertebral fractures: orthopedic bracing, percutaneous vertebroplasty, and spinal arthrodesis.
- Conditions
- Traumatic Vertebral Fractures, Compression Fractures of the Spine, AO Type A1 Vertebral Fracture, Spinal Trauma
- Trial name
- TRAUMA-A1 (NCT07471568)
- Where
- Spain
- Volunteers
- 146 people
- Sponsor
- University of Valencia
Osteoporosis
Addressing Vertebral Osteoporosis Incidentally Detected to Prevent Future Fractures
Osteoporosis is a common and progressive condition that leads to broken bones (fractures), which cause pain, disability, deformity, and even death.
- Trial name
- AVOID Fracture (NCT00388908)
- Testing
- Reminders and opinion leader generated guidelines +/- leaflets and counselling, Usual Care
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- University of Alberta
Low Back Pain, Cervical Pain
Prospective Study of Post Surgical Continued Spinal Pain Patients
Continued spinal pain following spine surgery is reported in up to 50% of patients. Disability and pain following spine surgery occurs.
- Conditions
- Low Back Pain, Cervical Pain, Neck Disorder, Low Back Disorder
- Trial name
- NCT05401682
- Testing
- Cox chiropractic care
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Keiser University College of Chiropractic Medicine
Spinal Injuries
Comparison by Neuromonitoring of Two Techniques of Tracheal Intubation in Patients With Unstable Cervical Spine
Patients who present with an unstable cervical spine following an accident need a general anesthesia for the necessary surgery. Commonly, the management of the tracheal intubation is performed by a fiberoptic technique.
- Trial name
- NCT02382887
- Testing
- tracheal intubation, Airtraq, fiberscope
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Lausanne Hospitals
Cancer of Thyroid, Vertebral Fracture
Study of the Prevalence of Osteo-metabolic Complications in Patients With Thyroid Cancer
This is a multicenter retrospective observational study aimed to evaluate the prevalence of osteo-metabolic complications in patients with thyroid cancer.
- Conditions
- Cancer of Thyroid, Vertebral Fracture, Osteoporosis
- Trial name
- NCT06627998
- Testing
- Diagnostic (chest x-ray /DXA)and clinical data collected for clinical practice
- Where
- Italy
- Volunteers
- 82 people
- Sponsor
- IRCCS San Raffaele
Spine Fracture
Comparison of Short Segment Mono-axial and Poly-axial Pedicle Screw Fixation for Thoracolumbar Fractures
Comparison of short segment mono axial and poly axial pedicle screw fixation in thoracolumbar fractures regarding the best correction of the fracture and deformity and the maintenance of the correction.
- Trial name
- NCT04032054
- Testing
- mono-axial and poly-axial screws
- Volunteers
- 50 people
- Sponsor
- Assiut University
Melanoma, Metastatic Malignant Neoplasm in the Spine
Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by Surgery
This pilot clinical trial studies adaptive staged stereotactic body radiation therapy (SBRT) in treating patients with spinal metastases that cannot be removed by surgery.
- Conditions
- Melanoma, Metastatic Malignant Neoplasm in the Spine, Renal Cell Carcinoma, Soft Tissue Sarcoma
- Trial name
- NCT02527304
- Testing
- Image-Guided Adaptive Radiation Therapy, Quality-of-Life Assessment, Questionnaire Administration
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Albert Einstein College of Medicine
Traumatic Burst Fractures of the Thoracic or Lumbar Spine., Normal Neurological Function
Thoracic And Lumbar Burst Fracture: Correlation Between Structural Changes And Clinical Outcome Of Treatment
Evaluate the correlation between the structural changes of fractures of the thoracic and lumbar spine burst type with clinical outcome of the treatment.
- Trial name
- NCT02076607
- Testing
- Arthrodesis, Brace
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- Hospital Ortopedico de Passo Fundo
Spondylolisthesis
Posterior Lateral Fusion (PLF) With Dynesys
The primary purpose of this study is to track and document the clinical outcomes of patients with radicular pathology following posterior lateral fusion with the Dynesys Spinal System.
- Trial name
- NCT00791180
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Zimmer Biomet
Hip-surgery, Knee-surgery
Prospective, Randomized Study of 2 Different Wound Dressings
The primary objective of this investigation is to evaluate the performance of a self-adhesive absorbent post-operative dressing coated with a soft silicone layer in minimize the risk of the development of blistering in subjects…
- Conditions
- Hip-surgery, Knee-surgery, Spinal-surgery
- Trial name
- Close (NCT01988818)
- Testing
- Mepilex® Border Post-Op, standard wound dressing
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Cologne
Exercise Addiction, Vertebral Fracture
Osteoporotic Vertebral Fractures and Exercise
Physiotherapy has an important place in the treatment of osteoporotic vertebral fractures. Therapeutic exercise is often recommended for patients with vertebral fractures to reduce pain and restore functional movement.
- Trial name
- NCT05521724
- Testing
- exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Hasan Kalyoncu University
Postmenopausal Osteoporosis, Vertebral Fracture
How Vertebral Fractures Effect Balance In Postmenopausal Women
Osteoporosis is defined as low bone mineral density caused by altered bone microstructure, ultimately predisposing patients to fragility fractures.
- Conditions
- Postmenopausal Osteoporosis, Vertebral Fracture, Fracture of Vertebra, Fall
- Trial name
- NCT06502301
- Testing
- Cross-sectional study
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people
- Sponsor
- Istanbul University - Cerrahpasa
Spinal Fractures, Fractures, Compression
The Kiva® System as a Vertebral Augmentation Treatment
The purpose of this study is to evaluate the safety and effectiveness of the Kiva VCF Treatment system in comparison to balloon kyphoplasty for the treatment of osteoporotic vertebral compression fractures of the thoracic or…
- Conditions
- Spinal Fractures, Fractures, Compression, Back Injuries
- Trial name
- KAST (NCT01123512)
- Testing
- Vertebral augmentation
- Where
- 21 sites in United States, Belgium and 3 more
- Volunteers
- 300 people
- Sponsor
- Benvenue Medical, Inc.
Spinal Cord Injuries
Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with…
- Trial name
- NCT02323945
- Testing
- AIH, Walk, Strength
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Adult Spinal Cord Neoplasm, Spinal Bone Metastases
Beta-Tricalcium Phosphate Bone Graft in Treating Patients Undergoing Surgery For Metastatic Spine Cancer
This pilot clinical trial studies beta-tricalcium phosphate bone graft in treating patients undergoing surgery for metastatic spine cancer.
- Conditions
- Adult Spinal Cord Neoplasm, Spinal Bone Metastases, Spinal Cord Compression
- Trial name
- NCT01407341
- Testing
- musculoskeletal complications management/prevention, bone graft, quality-of-life assessment
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Southern California
Osteoporosis, Vertebral Fracture
A Trial of Vertebroplasty for Painful Acute Osteoporotic Vertebral Fractures
The standard care in patients with a painful osteoporotic vertebral compression fracture (VCF) is conservative therapy. Percutaneous vertebroplasty (PV), is a new minimally invasive technique for pain treatment in which bone…
- Trial name
- VertosIV (NCT01200277)
- Testing
- percutaneous vertebroplasty
- Where
- 4 sites in Netherlands
- Volunteers
- 80 people
- Sponsor
- Elisabeth-TweeSteden Ziekenhuis
Osteoporosis, Multiple Myeloma
Investigation of Bone Defects and Microcirculation With Computed Tomography and Magnetic Resonance Imaging
Subject of the proposed study is the non-invasive in vivo imaging of bone, bone marrow and localized microcirculation in test animals with osteoporosis, fractures and after placement of bone substitute material with volume…
- Conditions
- Osteoporosis, Multiple Myeloma, Vertebral Fracture
- Trial name
- NCT01374412
- Where
- Germany
- Volunteers
- 144 people
- Sponsor
- German Cancer Research Center