Clinical trials: Spine
Hyperkyphosis, Adolescent, Muscle Activation
Schroth and Scapular Muscle Activation in Hyperkyphosis
This randomized controlled trial aims to investigate the effects of Schroth exercises on scapular muscle activation in children with thoracic hyperkyphosis.
- Conditions
- Hyperkyphosis, Adolescent, Muscle Activation, Scapula; Deformity, Acquired, Exercise Therapy
- Trial name
- NCT06907914
- Testing
- Schroth
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Istanbul University - Cerrahpasa
Obesity, Lumbar Spine Surgery
WoundVac in Obese Patients Undergoing Lumbar Surgery
This is an open label, randomized clinical trial of Closed-Incision Negative-Pressure Therapy to decrease post-operative wound complications in patients with BMI ≥35kg/m2 after posterior lumbar spine surgery.
- Trial name
- NCT03688438
- Testing
- Closed-Incision Negative-Pressure Therapy
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Norton Leatherman Spine Center
Pain
Efficacy of "Tailored Physical Activity" in Health Care Workers
The purpose of this study is to test the effect of "Tailored Physical Activity" on the number of sick-days. The hypothesis is that "Tailored Physical Activity" is superior in efficacy on sick-days.
- Trial name
- NCT01543984
- Testing
- Tailored Physical Activity, Health Counselling
- Where
- Denmark
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Thoracolumbar Scoliosis
A Trial Comparing Single Intra-op Dose of Methadone Versus Placebo in Patients Undergoing Spine Surgery
Scoliosis is a disease that involves lateral and/or rotational deformity of the spine and can affect up to 4% of the population.
- Trial name
- NCT02206685
- Testing
- Methadone, Normal Saline
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Whiplash Injury of Cervical Spine
Rehabilitation for Whiplash Associated Disorders
Individuals (n=180) with subacute (<1 month, >3 months) WAD grade I and II with medium to high-risk symptoms of working age will be randomized into three groups with block randomization in a prospective, assessor-blinded…
- Trial name
- NCT05319808
- Testing
- Manual therapy, Telehealth exercises, Non-computer based exercises
- Where
- 4 sites in Iceland
- Volunteers
- 180 people
- Sponsor
- University of Iceland
Pain
Ultrasound-Guided Technique for Thoracic Epidural Insertion
Thoracic epidural analgesia and anesthesia are effective in improving the quality of intraoperative and postoperative pain relief during thoracic and abdominal surgical procedures.
- Trial name
- NCT01449214
- Testing
- Ultrasound, Landmarking
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Spine Injuries and Disorders
Evaluation Of Intra-Operative Neuro-Monitoring Alarm During Complex Spine Surgery
Iatrogenic spinal cord injury is the most feared complication of complex spine surgery. The incidence of neurological complications for spinal deformity surgery has been estimated by the Scoliosis Research Society as 1%, except…
- Trial name
- NCT05710016
- Volunteers
- 64 people
- Sponsor
- Assiut University
Pain, Back
Implementation of the ACP Guideline for Low Back Pain (IMPACt-LBP)
The purpose of this study is to assess whether the primary spine practitioner (PSP) model of care will lead to improvements in patient outcomes, as compared to usual care, based on change in patient-reported PROMIS Pain…
- Trial name
- IMPACt-LBP (NCT05626049)
- Testing
- Primary Spine Provider Model, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 1,800 people
- Sponsor
- Duke University
Spine Surgery
Pregabalin Effects on Hypotensive Anesthesia During Spine Surgery.
Elective lumbar spine surgical procedures are commonly performed under controlled hypotension during general anesthesia. That is beneficial to limit the intraoperative blood loss and transfusions and improves surgical field.
- Trial name
- NCT03301025
- Testing
- Pregabalin
- Where
- 2 sites in Egypt
- Volunteers
- 106 people
- Sponsor
- Mansoura University
Lumbar Spine Disease, Lumbar Spondylolisthesis
OSTEOAMP Lumbar Fusion Intra-Patient Controlled Study
The objective of this clinical study is to compare OSTEOAMP SELECT Fibers to Infuse Bone Graft, in terms of effectiveness and safety, when used as a bone graft substitute in in skeletally mature patients qualified for 2-lumbar…
- Conditions
- Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis
- Trial name
- SELECT (NCT05405374)
- Testing
- OSTEOAMP, Infuse
- Where
- 9 sites in United States
- Volunteers
- 101 people
- Sponsor
- Bioventus LLC
Septicaemia, Deformity of Spine
The Paediatric Refill Study (PRefill)
2 recent national reports 'Why Children Die' and 'Are we there yet?'identified deficiencies in recognising and managing sick children.
- Conditions
- Septicaemia, Deformity of Spine, Trauma
- Trial name
- PRefill (NCT02208817)
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University of Nottingham
Whiplash Injury of Cervical Spine, Osteopathia
The Effectiveness of Osteopathic Treatment in Cervical Whiplash.
Introduction. Whiplash is common after road traffic accidents and affects millions of people worldwide; 50% develop chronic symptoms and 15% have their ability to work compromised.
- Conditions
- Whiplash Injury of Cervical Spine, Osteopathia, Quality of Life, Chronic Pain Syndrome
- Trial name
- NCT06334978
- Testing
- Osteopathic intervention
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Hospital San Juan de Dios del Aljarafe de Sevilla
Spine Fusion
Pedicle Screw Placement With XVS
Open label, prospective, single arm, multi-center study. Pedicle screws placement in sacral/lumbar vertebrae will be performed via open procedural technique, by at least two (2) different surgeons, using the XVISION SPINE system.
- Trial name
- NCT04682418
- Testing
- xvision Spine sytem
- Where
- 3 sites in Israel
- Volunteers
- 19 people
- Sponsor
- Augmedics
Arthritis of Knee, Arthritis of Hip
Comparison of the Diagnosis Time of VET and SCL in Patients With Intraoperative Coagulopathy
The present study is a prospective, multi-center observational trial comparing the times taken to diagnose coagulopathies using point-of-care (POC) viscoelastic tests or standard central laboratory tests (SCL tests) in patients…
- Conditions
- Arthritis of Knee, Arthritis of Hip, Spine, Prostate Cancer
- Trial name
- NCT06637943
- Testing
- SCL tests, POC viscoelastic tests
- Where
- 4 sites in South Korea
- Volunteers
- 210 people
- Sponsor
- Konkuk University Medical Center
Central Nervous System Diseases
Efficacy and Safety Study to Evaluate Gadavist (Gadobutrol) as Contrast Agent in Magnetic Resonance Imaging (MRI) of Brain or Spine Diseases in Chinese Patients
The purpose of this study is to determine if the contrast agent is effective and safe in the Magnetic Resonance Imaging (MRI) of brain or spine diseases in patients of Chinese origin.
- Trial name
- NCT00395460
- Testing
- Gadobutrol (Gadavist, Gadovist, BAY86-4875), Magnevist
- Where
- 4 sites in China
- Volunteers
- 147 people
- Sponsor
- Bayer
Sciatic Radiculopathy
Contralateral Leg Neuro-dynamic and Spine Mobilization With Leg Movement in Patients With Sciatica
The aim of this randomized clinical trial is to find the comparison of CLNDT and SMWLM technique in diabetic and non-diabetic sciatica patients on reducing back pain and improving range of motion of knee
- Trial name
- NCT06556823
- Testing
- CLNDT+ Conventional PT in Diabetic Population):, CLNDT+ Conventional PT in non Diabetic Population):, SMWLM+ Conventional PT in Diabetic Population)
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Riphah International University
Lumbar Disc Disease, Lumbar Spine Degeneration
The Six-Minute Walking Test (6WT) and Timed-Up-and-Go (TUG) Test as Measures of Objective Functional Impairment in Patients Undergoing Interlaminar or Transforaminal Epidural Steroid Injection for Lumbar Degenerative Disc Disease (DDD)
The primary objective is to determine the validity of the Six-Minute-Walking Test (6WT) and Timed-Up and Go (TUG) test to measure objective functional impairment (OFI) in patients undergoing either interlaminar epidural steroid…
- Conditions
- Lumbar Disc Disease, Lumbar Spine Degeneration, Lumbar Spinal Stenosis
- Trial name
- NCT04062942
- Where
- 2 sites in Switzerland
- Volunteers
- 50 people
- Sponsor
- Cantonal Hospital of St. Gallen
Spine Surgery
Safety of Tranexamic Acid in Reducing Bleeding in Adults Undergoing Spinal Surgery
Spinal fusion surgery can be associated with significant blood loss requiring allogeneic blood transfusion. Tranexamic acid is a synthetic amino acid with antifibrinolytic action that has been shown to reduce perioperative blood…
- Trial name
- NCT00444470
- Testing
- Tranexamic acid
- Where
- 3 sites in Canada
- Volunteers
- 151 people
- Sponsor
- University Health Network, Toronto
Neck Pain, Cervical Spine Disease
Indirect Approach of C0-1 and C2-3 Segments in Flexion-rotation Test
Restrictions on upper cervical spine are associated with cervical pain. The vast majority of upper cervical spine rotation occurs at the C1-2 segment.
- Conditions
- Neck Pain, Cervical Spine Disease, Rotation
- Trial name
- NCT04406753
- Testing
- Manual therapy techniques in C0-1 and C2-3 with cervical exercise, Cervical Exercise
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Universidad de Zaragoza
Spine Fracture, Osteoporosis
Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series
Retrospective observational
- Conditions
- Spine Fracture, Osteoporosis, Spondylitis, Ankylosing
- Trial name
- NCT07847320
- Volunteers
- 23 people
- Sponsor
- Diakonie-Klinikum Stuttgart
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