Clinical trials: Spinal Pain
Low Back Pain, Mechanical, Recreational Physical Activity
The Effects of Spinal Mobilization Added to an Exercise Program in Recreational Tennis Players With Mechanical Low Back Pain
This prospective, single-blind, randomized controlled trial investigates whether the addition of spinal mobilization to a structured home exercise program improves pain, flexibility, lower-extremity strength, dynamic balance, and…
- Conditions
- Low Back Pain, Mechanical, Recreational Physical Activity, Tennis, Manual Therapy
- Trial name
- NCT07573254
- Testing
- Home Exercise Program, Spinal Mobilization (Maitland-Graded Manual Therapy)
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Istinye University
Anesthesia
Oral Duloxetine as a Premedication for Postoperative Pain Control
The purpose of the study is to use duloxetine as premedication in Anterior cruciate ligament repair under spinal anesthesia and evaluate the effect on onset and duration of spinal anesthesia and postoperative pain control.
- Trial name
- NCT05050656
- Testing
- Duloxetine 60mg
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Analgesia, Arthropathy of Knee
Comparison of Two Different Regional Analgesia Techniques for Patients Undergoing Total Knee Arthroplasty
The objective of this clinical trial is to compare two regional analgesia techniques in patients undergoing total knee arthroplasty: IPACK (Infiltration of local anesthetic between the Popliteal Artery and Capsule of the Knee) vs…
- Conditions
- Analgesia, Arthropathy of Knee, Postoperative Pain
- Trial name
- PIPACK (NCT06179641)
- Testing
- Selective tibial nerve block, IPACK block
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Manipulation, Osteopathic, Pilates Exercise
The Effects of Manipulation on Pain, Quality of Life, and Functional Activity in People Who Practice Pilates.
Participants were randomly divided into two groups: a Pilates group (n=20) and a Pilates and spine-total body manipulation group (n=20).
- Conditions
- Manipulation, Osteopathic, Pilates Exercise, Non-specific Spinal Problems
- Trial name
- NCT07466368
- Testing
- manuel therapy, pilates
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Istanbul Rumeli University
Neuralgia, Spinal Cord Stimulation
Examining Carryover Effect in Patients Treated witH Spinal cOrd Stimulation (ECHO)
Spinal cord stimulation is a minimally invasive surgical treatment for severe, chronic, neuropathic pain that is refractory to conventional treatment.
- Trial name
- ECHO (NCT03386058)
- Testing
- Temporary device deactivation
- Where
- 10 sites in Belgium, Canada and 4 more
- Volunteers
- 200 people
- Sponsor
- University of Aarhus
Spinal Cord Injuries
Influence of Spinal Stimulation Frequency on Spasticity, Motor Control, and Pain After Spinal Cord Injury
The goal of this study is to identify the effect of different types of noninvasive spinal stimulation on spasticity (involuntary muscle activity), muscle strength, and pain in people with spinal cord injury.
- Trial name
- NCT06214208
- Testing
- Transcutaneous Spinal Stimulation
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Shepherd Center, Atlanta GA
Lower Back Pain
A Clinical Study of the GO-LIF® Approach for Lumbar Spinal Fixation
The purpose of this study is to collect data regarding the safety and feasibility of the GO-LIF procedure for spinal fixation and stabilization, in conjunction with conventional approaches for interbody lumbar fusion.
- Trial name
- NCT00810433
- Testing
- GO-LIF - Guided Oblique Lumbar Interbody Fusion
- Where
- 10 sites in Germany, Israel
- Volunteers
- 10 people
- Sponsor
- Mazor Robotics
Cancer, Shoulder Pain
Effectiveness of Oncological Physiotherapy on Painful Shoulder Cervical Ganglion in Head and Neck Cancer
Objective: To estimate whether oncological physiotherapy treatment with neurodynamic and kinesitherapy (passive and active) in patients with "painful shoulder due to accessory spinal nerve dissection" operated on for head and…
- Conditions
- Cancer, Shoulder Pain, Rehabilitation
- Trial name
- NCT05604235
- Testing
- Therapeutic upper limb strength exercise treatment, Treatment with passive and active mobilization of the upper limb.
- Where
- 3 sites in Spain
- Volunteers
- 20 people
- Sponsor
- University of Alcala
Vertebral Fracture, Multiple Myeloma
Examination of Vertebroplasty in Addition to Regular Treatment of Patients With Multiple Myeloma.
Patients with newly diagnosed or known multiple myeloma with newly diagnosed vertebral lesion(s) will be invited to participate in a cross-sectoral randomized controlled trial.
- Trial name
- NCT04533217
- Testing
- Vertebroplasty
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Spine Centre of Southern Denmark
Spinal Stenosis Lumbar
Coflex PS3 Actual Conditions for Use Study
A 2 and 5 year evaluation of clinical outcomes in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with additional stabilization using the coflex® Interlaminar Technology for FDA…
- Trial name
- PAS003 (NCT02555280)
- Testing
- coflex® Interlaminar Technology, Decompression
- Where
- 14 sites in United States
- Volunteers
- 40 people
- Sponsor
- Companion Spine, LLC
Post Operative Pain, Bradycardia
Comparison of EOSP Between Usg Guided S-FICB vs USG Guided PENG Block in Pts Undergoing Femur Fracture Surgery
To compare the immediate and postoperative analgesic efficacy of S-FICB and PENG block will be the objective. The use of ultrasonography in anesthesia has helped the anesthetist to see the nerve, needle and the distribution of…
- Conditions
- Post Operative Pain, Bradycardia, Hypotension, Femur Fracture
- Trial name
- NCT06568770
- Testing
- USG GUIDED SUPRA-INGUINAL FASCIA ILIACA BLOCK, PERICAPSULAR NERVE BLOCK
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Sahiwal medical college sahiwal
Pain, Pain Postoperative
The Effects of Body Mass Index on Erector Spinae Plane Block Analgesia
In recent years, obesity has become one of the leading health problems worldwide. It is known that obesity can cause various diseases and negatively impact the quality of life.
- Conditions
- Pain, Pain Postoperative, Pain Acute, Erector Spinae Plane Block
- Trial name
- NCT06257953
- Testing
- Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Neck Pain, Cervical Spondylosis
Radiofrequency Plus Superficial Cervical Plexus Block in Treatment of Cervical Spondylosis Pain
The goal of this clinical trial is to compare the effectiveness in the pain relief between doing radiofrequency ablation for the medial branch of the cervical facet pain alone vs using it combined with superficial cervical plexus…
- Trial name
- NCT06480175
- Testing
- cervical plexus block
- Where
- Egypt
- Volunteers
- 53 people
- Sponsor
- Ain Shams University
Low Back Pain
Clinical, Morphological and Functional Success Predictors Following Lumbar Spinal Surgery in Patients With Chronic Low Back Pain and Degenerative Disorders.
The long term goal of this project is dual fold. First, the investigators wish to derive, validate and then test the impact of a clinical prediction rule to determine which patients who suffer from CLBP with degenerative changes…
- Trial name
- NCT02444702
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Meir Medical Center
Failed Back Surgery Syndrome
Effectiveness and Cost Management of Multicolumn Spinal Cord Stimulation in Neuropathic Pain Patients With Failed Back Surgery Syndrome
Failed back surgery syndrome (FBSS) constitutes a frequent pathology, generates a severe handicap for patients and represents a considerable expense for healthcare system.
- Trial name
- ESTIMET (NCT01628237)
- Testing
- comparison of spinal cord stimulation
- Where
- France
- Volunteers
- 115 people
- Sponsor
- Poitiers University Hospital
Radiating Pain, Myelopathy
Interbody Fusion Devices in the Treatment of Cervicobrachial Syndrome
This study randomizes neck and arm pain patients being treated with discectomy and anterior interbody fusion into two groups: one to receive a new ceramic implant and a control group with a more traditional plastic implant.
- Conditions
- Radiating Pain, Myelopathy, Cervicobrachial Syndrome
- Trial name
- CASCADE (NCT01511445)
- Testing
- Anterior cervical discectomy and fusion (ACDF) with PEEK Cage, Anterior cervical discectomy and fusion (ACDF) with a Valeo CSC Cage
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Amedica Corporation
Low Back Pain
Effect of Two Osteopathic Techniques on Thickness of Paravertebral Muscles of the Lumbar Spine
The objective of this randomized controlled trial is to describe the effect of two osteopathic techniques - "high velocity, low amplitude" (HVLA) and muscle energy (ME) - on thickness, activation, strength, pressure pain…
- Trial name
- NCT01971983
- Testing
- High-velocity, low-amplitude (HVLA), Muscle energy (ME)
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Federal University of Health Science of Porto Alegre
Spinal Cord Injury
Evaluation of a Specialized Yoga Program for Persons With Spinal Cord Injury (SCI)
The purpose of this randomized controlled study is to evaluate psychological variables, mindfulness, and pain in the context of a specialized yoga program for individuals with SCI.
- Trial name
- SCI (NCT02656927)
- Testing
- Yoga Condition
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto
Spinal Fusion, Hyperglycemia
Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery
This study is a randomized controlled trial that will evaluate the effect of non-invasive auricular vagal nerve stimulation on inflammatory markers, glycemic control, postoperative pain, and inflammation-related clinical outcomes…
- Conditions
- Spinal Fusion, Hyperglycemia, Postoperative Pain Management, Postoperative Care
- Trial name
- TAPIS (NCT07218133)
- Testing
- Auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Alexander T. Yahanda
Pain, Chronic, Failed Back Surgery Syndrome
Burst Spinal Cord Stimulation (Burst-SCS) Study
Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain.
- Trial name
- NCT03718325
- Testing
- Burst-SCS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan